-
2
-
-
0023786551
-
Age-dependent expression of familial risk in Alzheimer's disease
-
Breitner JC, Murphy EA, Silverman JM, et al. Age-dependent expression of familial risk in Alzheimer's disease. Am J Epidemiol 1988;128:536-548
-
(1988)
Am J Epidemiol
, vol.128
, pp. 536-548
-
-
Breitner, J.C.1
Murphy, E.A.2
Silverman, J.M.3
-
3
-
-
0024347981
-
Assessment of genetic risk for Alzheimer's disease among first-degree relatives
-
Farrer LA, O'Sullivan DM, Cupples LA, et al. Assessment of genetic risk for Alzheimer's disease among first-degree relatives. Ann Neurol 1989; 25:485-493
-
(1989)
Ann Neurol
, vol.25
, pp. 485-493
-
-
Farrer, L.A.1
O'Sullivan, D.M.2
Cupples, L.A.3
-
4
-
-
0027497511
-
Clinical, neuroimaging, and environmental risk differences in monozygotic female twins appearing discordant for dementia of the Alzheimer type
-
Small GW, Leuchter A, Mandelkern MA, et al. Clinical, neuroimaging, and environmental risk differences in monozygotic female twins appearing discordant for dementia of the Alzheimer type. Arch Neurol 1993;50:209-219
-
(1993)
Arch Neurol
, vol.50
, pp. 209-219
-
-
Small, G.W.1
Leuchter, A.2
Mandelkern, M.A.3
-
5
-
-
0020692622
-
A family with histologically confirmed Alzheimer's disease
-
Nee LE, Polinsky RJ, Eldridge R, et al. A family with histologically confirmed Alzheimer's disease. Arch Neurol 1983;40:203-208
-
(1983)
Arch Neurol
, vol.40
, pp. 203-208
-
-
Nee, L.E.1
Polinsky, R.J.2
Eldridge, R.3
-
6
-
-
0023103748
-
The genetic defect causing familial Alzheimer's disease maps on chromosome 21
-
St. George-Hyslop PH, Tanzi RE, Polinsky RJ, et al. The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science 1987;235:885-890
-
(1987)
Science
, vol.235
, pp. 885-890
-
-
St. George-Hyslop, P.H.1
Tanzi, R.E.2
Polinsky, R.J.3
-
7
-
-
0025179972
-
Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder
-
St. George-Hyslop PH, Haines JL, Farrer LA, et al. Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature 1990;347:194-197
-
(1990)
Nature
, vol.347
, pp. 194-197
-
-
St. George-Hyslop, P.H.1
Haines, J.L.2
Farrer, L.A.3
-
8
-
-
0024203266
-
Genetic linkage studies in Alzheimer's disease families
-
Pericak-Vance MA, Yamaoka LH, Haynes CS, et al. Genetic linkage studies in Alzheimer's disease families. Exp Neurol 1988;102:271-279
-
(1988)
Exp Neurol
, vol.102
, pp. 271-279
-
-
Pericak-Vance, M.A.1
Yamaoka, L.H.2
Haynes, C.S.3
-
9
-
-
0023722957
-
Absence of linkage of chromosome 21q21 markers to familial Alzheimer's disease
-
Schellenberg GD, Bird TD, Wijsman EM, et al. Absence of linkage of chromosome 21q21 markers to familial Alzheimer's disease. Science 1988; 241:1507-1510
-
(1988)
Science
, vol.241
, pp. 1507-1510
-
-
Schellenberg, G.D.1
Bird, T.D.2
Wijsman, E.M.3
-
10
-
-
0023132387
-
Characterization and chromosomal localization of cDNA encoding brain amyloid of Alzheimer's disease
-
Goldgaber D, Lerman MI, McBride OW, et al. Characterization and chromosomal localization of cDNA encoding brain amyloid of Alzheimer's disease. Science 1987;235:877-880
-
(1987)
Science
, vol.235
, pp. 877-880
-
-
Goldgaber, D.1
Lerman, M.I.2
McBride, O.W.3
-
11
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E, Wasco W, Poorkaj P, et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 1995;269:973-977
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
-
12
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev EI, Sherrington R, Rogaeva EA, et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 1995:376:775-778
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
-
13
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R, Rogaev EI, Liang Y, et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 1995; 375:754-760
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
-
14
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A, Chartier-Harlin M-C, Mullan M, et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991;349:704-706
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
-
15
-
-
0025735884
-
Linkage studies in familial Alzheimer's disease: Evidence for chromosome 19 linkage
-
Pericak-Vance MA, Bebout JL, Gaskell PC Jr, et al. Linkage studies in familial Alzheimer's disease: evidence for chromosome 19 linkage. Am J Hum Genet 1991;48:1034-1050
-
(1991)
Am J Hum Genet
, vol.48
, pp. 1034-1050
-
-
Pericak-Vance, M.A.1
Bebout, J.L.2
Gaskell Jr., P.C.3
-
16
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 1993; 90:1977-1981
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
-
17
-
-
0027327267
-
Association of apolipoprotein e allele ε4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993;43:1467-1472
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
-
19
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993;261:921-923
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
-
20
-
-
0028305380
-
Protective effect of apolipoprotein e type 2 allele for the late onset Alzheimer disease
-
Corder EH, Saunders AM, Risch NJ, et al. Protective effect of apolipoprotein E type 2 allele for the late onset Alzheimer disease. Nature Genetics 1994;7:180-184
-
(1994)
Nature Genetics
, vol.7
, pp. 180-184
-
-
Corder, E.H.1
Saunders, A.M.2
Risch, N.J.3
-
21
-
-
0001777764
-
Alzheimer's disease as a model of molecular gerontology
-
Roses AD. Alzheimer's disease as a model of molecular gerontology. Journal of NIH Research 1995;7:51-57
-
(1995)
Journal of NIH Research
, vol.7
, pp. 51-57
-
-
Roses, A.D.1
-
22
-
-
0028238408
-
Emerging drugs for Alzheimer's disease: Mechanisms of action and prospects for cognitive enhancing medications
-
Schneider LS, Tariot PN. Emerging drugs for Alzheimer's disease: mechanisms of action and prospects for cognitive enhancing medications. Med Clin North Am 1994;78:911-934
-
(1994)
Med Clin North Am
, vol.78
, pp. 911-934
-
-
Schneider, L.S.1
Tariot, P.N.2
-
23
-
-
0027365822
-
Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein e genotype in late-onset Alzheimer's disease
-
Schmechel DE, Saunders AM, Strittmatter WJ, et al. Increased amyloid β-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer's disease. Proc Natl Acad Sci USA 1993;90:9649-9653
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
-
24
-
-
15844421384
-
Use of genetically engineered mice as models for understanding human neurodegenerative disease
-
Andersen JK, Jurma OP. Use of genetically engineered mice as models for understanding human neurodegenerative disease. J Am Geriatr Soc 1996; 44:717-722
-
(1996)
J Am Geriatr Soc
, vol.44
, pp. 717-722
-
-
Andersen, J.K.1
Jurma, O.P.2
-
25
-
-
0029949755
-
APP transgenesis: Approaches toward the development of animal models for Alzheimer disease neuropathology
-
Greenberg BD, Savage MJ, Howland DS, et al. APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology. Neurobiol Aging 1996;17:153-171
-
(1996)
Neurobiol Aging
, vol.17
, pp. 153-171
-
-
Greenberg, B.D.1
Savage, M.J.2
Howland, D.S.3
-
26
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of department of health and human services task force on Alzheimer's disease
-
McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of department of health and human services task force on Alzheimer's disease. Neurology 1984;34:939-944
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
-
27
-
-
0028784189
-
Predictors of cognitive change in middle-aged and older adults with memory loss
-
Small GW, La Rue A, Komo S, et al. Predictors of cognitive change in middle-aged and older adults with memory loss. Am J Psychiatry 1995; 152:1757-1764
-
(1995)
Am J Psychiatry
, vol.152
, pp. 1757-1764
-
-
Small, G.W.1
La Rue, A.2
Komo, S.3
-
28
-
-
12644257180
-
Early detection of Alzheimer's disease by combining apolipoprotein e and neuroimaging
-
Small GW, Komo S, La Rue A, et al. Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging. Ann N Y Acad Sci. In press
-
Ann N Y Acad Sci. in Press
-
-
Small, G.W.1
Komo, S.2
La Rue, A.3
-
29
-
-
0000706869
-
Positron emission tomography studies of the brain
-
Phelps ME, Mazziotta JC, Schelbert HR, eds. New York, NY: Raven Press
-
Mazziotta JC, Phelps ME. Positron emission tomography studies of the brain. In: Phelps ME, Mazziotta JC, Schelbert HR, eds. Positron Emission Tomography and Autoradiography: Principles and Applications for the Brain and Heart. New York, NY: Raven Press; 1986:493-579
-
(1986)
Positron Emission Tomography and Autoradiography: Principles and Applications for the Brain and Heart
, pp. 493-579
-
-
Mazziotta, J.C.1
Phelps, M.E.2
-
30
-
-
0026939084
-
The use of positron emission tomography in the clinical assessment of dementia
-
Mazziotta JC, Frackowiak RSJ, Phelps ME. The use of positron emission tomography in the clinical assessment of dementia. Semin Nucl Med 1992; 22:233-246
-
(1992)
Semin Nucl Med
, vol.22
, pp. 233-246
-
-
Mazziotta, J.C.1
Frackowiak, R.S.J.2
Phelps, M.E.3
-
31
-
-
0022619098
-
Positron emission tomography in Alzheimer's disease
-
Duara R, Grady C, Haxby J, et al. Positron emission tomography in Alzheimer's disease. Neurology 1986;36:879-887
-
(1986)
Neurology
, vol.36
, pp. 879-887
-
-
Duara, R.1
Grady, C.2
Haxby, J.3
-
32
-
-
0026680856
-
Evaluation of a neural-network classifier for PET scans of normal and Alzheimer's disease subjects
-
Kippenhan SJ, Barker WW, Pascal S, et al. Evaluation of a neural-network classifier for PET scans of normal and Alzheimer's disease subjects. J Nucl Med 1992;33:1459-1467
-
(1992)
J Nucl Med
, vol.33
, pp. 1459-1467
-
-
Kippenhan, S.J.1
Barker, W.W.2
Pascal, S.3
-
33
-
-
0026609568
-
Blinded clinical evaluation of positron emission tomography for diagnosis of probable Alzheimer's disease
-
Powers WJ, Perlmutter JS, VideenTO, et al. Blinded clinical evaluation of positron emission tomography for diagnosis of probable Alzheimer's disease. Neurology 1992;42:765-770
-
(1992)
Neurology
, vol.42
, pp. 765-770
-
-
Powers, W.J.1
Perlmutter, J.S.2
Videen, T.O.3
-
34
-
-
0025015699
-
Criteria for the diagnosis of Alzheimer's disease with positron emission tomography
-
Herholz K, Adams R, Kessler J, et al. Criteria for the diagnosis of Alzheimer's disease with positron emission tomography. Dementia 1990;1: 156-164
-
(1990)
Dementia
, vol.1
, pp. 156-164
-
-
Herholz, K.1
Adams, R.2
Kessler, J.3
-
35
-
-
0028950856
-
Apolipoprotein e type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease
-
Small GW, Mazziotta JC, Collins MT, et al. Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease. JAMA 1995;273:942-947
-
(1995)
JAMA
, vol.273
, pp. 942-947
-
-
Small, G.W.1
Mazziotta, J.C.2
Collins, M.T.3
-
36
-
-
0028821049
-
Decreased hippocampal volume asymmetry on MRIs in nondemented elderly subjects carrying the apolipoprotein e ε4 allele
-
Soininen H, Partanen K, Pitkänen A, et al. Decreased hippocampal volume asymmetry on MRIs in nondemented elderly subjects carrying the apolipoprotein E ε4 allele. Neurology 1995;45:391-392
-
(1995)
Neurology
, vol.45
, pp. 391-392
-
-
Soininen, H.1
Partanen, K.2
Pitkänen, A.3
-
37
-
-
0029970342
-
Preclinical evidence of Alzheimer's disease in persons homozygous for the ε4 allele for apolipoprotein e
-
Reiman EM, Caselli RJ, Yun LS, et al. Preclinical evidence of Alzheimer's disease in persons homozygous for the ε4 allele for apolipoprotein E. N Engl J Med 1996:334:752-758
-
(1996)
N Engl J Med
, vol.334
, pp. 752-758
-
-
Reiman, E.M.1
Caselli, R.J.2
Yun, L.S.3
-
38
-
-
12644296589
-
Neuroimaging, neuropsychological, and genetic assessments for early detection of Alzheimer disease
-
Fitten LJ, ed. New York, NY: Springer-Verlag. In press
-
Small OW, Mazziotta JC, Baxter LR, et al. Neuroimaging, neuropsychological, and genetic assessments for early detection of Alzheimer disease. In: Fitten LJ, ed. Facts and Research in Gerontology: Alzheimer Disease. New York, NY: Springer-Verlag. In press
-
Facts and Research in Gerontology: Alzheimer Disease
-
-
Small, O.W.1
Mazziotta, J.C.2
Baxter, L.R.3
-
40
-
-
0029031466
-
Age-specific incidence of Alzheimer's disease in a community population
-
Hebert LE, Scherr PA, Beckett LA, et al. Age-specific incidence of Alzheimer's disease in a community population. JAMA 1995;273:1354-1359
-
(1995)
JAMA
, vol.273
, pp. 1354-1359
-
-
Hebert, L.E.1
Scherr, P.A.2
Beckett, L.A.3
-
41
-
-
0029944411
-
Apolipoprotein e genotyping in Alzheimer's disease
-
National Institute on Aging/Alzheimer's Association Working Group. Apolipoprotein E genotyping in Alzheimer's disease. Lancet 1996;347: 1091-1095
-
(1996)
Lancet
, vol.347
, pp. 1091-1095
-
-
|