DNA repair and colorectal cancer

Gastroenterology Clinics of North America

Volumn 25, Issue 4, 1996, Pages 755-772

  Marra, G ^a   Boland, C R ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA;

COLORECTAL CANCER; DNA REPAIR; GENE MUTATION; REVIEW;

EID: 0030462320     PISSN: 08898553     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-8553(05)70273-9     Document Type: Article

References (95)

1. L.A. Aaltonen P. Peltomaki F.S. Leach Clues to the pathogenesis of familial colorectal cancer Science 260 1993 812
2. L.A. Aaltonen P. Peltomaki Mecklin J.-P. Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients Cancer Res 54 1994 1645
3. E. Alani Chi N.-W. R. Kolodner The Saccharomyces cerevisiae MSH2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertion Genes Dev 9 1995 234
4. S.M. Baker C.E. Bronner L. Zhang Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis Cell 82 1995 309
5. 2-microglobulin gene mutations: A study of established colorectal cell lines and fresh tumors Proc Natl Acad Sci USA 91 1994 4751
6. D.K. Bishop M.S. Williamson S. Fogel The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiae Nature 328 1987 362
7. Borresen A.-L. R.A. Lothe G.I. Meling Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas Hum Molec Genet 4 1995 2065
8. P. Branch G. Aquilina M. Bignami Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage Nature 362 1993 652
9. P. Branch R. Hampson P. Karran DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines Cancer Res 55 1995 2304
10. C.E. Bronner S.M. Baker P.T. Morrison Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer Nature 368 1994 258
11. Buerstedde J.-M. P. Alday J. Torhorst Detection of new mutations in six out of 10 Swiss HNPCC families in genomic sequencing of the hMSH2 and hMSH1 genes J Med Genet 32 1995 909
12. N. Burns B. Grimwade P.B. Ross-Macdonald Large-scale analysis of gene expression, protein localization and gene disruption in Saccharomyces cerevisiae. Genes Dev 8 1994 1087
13. S. Casares Y. Ionov Ge H.-Y. The microsatellite mutator phenotype of colon cancer cells is often recessive Oncogene 11 1995 2303
14. F. Charbonnier C. Martin M. Scotte Alternative splicing of hMLH1 messenger RNA in human normal cells Cancer Res 55 1995 1839
15. Claverys J.-P. S.A. Lacks Heteroduplex deoxyribonucleic acid base mismatch repair in bacteria Microbiol Rev 50 1986 133
16. D.L. Cooper R.S. Lahue P. Modrich Methyl-directed mismatch repair is bidirectional J Biol Chem 268 1993 11823
17. A. Datta A. Adjiri L. New Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccharomyces cerevisiae Molec Cell Biol 16 1996 1085
18. de Wind N. M. Dekker A. Berns Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer Cell 82 1995 321
19. J.T. Drummond Li G.-M. M.J. Longley Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells Science 268 1995 1909
20. J.R. Eshleman S.D. Markowitz Microsatellite instability in inherited and sporadic neoplasms Curr Opin Oncol 7 1995 83
21. E.R. Fearon B. Vogelstein A genetic model for colorectal tumorigenesis Cell 61 1990 759
22. R. Fishel A. Ewel S. Lee Binding of mismatched microsatellite DNA sequences by the human MSH2 protein Science 266 1994 1403
23. R. Fishel M.K. Lescoe M.R.S. Rao The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer Cell 75 1993 1027
24. N. Froggatt J.A. Joyce R. Davies A frequenct hMSH2 mutation in hereditary nonpolyposis colon cancer syndrome Lancet 345 1995 727
25. V.S. Goldmacher Cuzick R.A. Jr W.G. Thilly Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N -Methyl- N′ -nitro- N -nitrosoguanidine J Biol Chem 261 1986 12462
26. M. Grilley J. Griffith P. Modrich Bidirectional excision in methyl-directed mismatch repair J Biol Chem 268 1993 11830
27. S.R. Hamilton B. Liu R.E. Parsons The molecular basis of Turcot's syndrome N Engl J Med 332 1995 839
28. Han H.-J. M. Maruyama S. Baba Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC) Hum Molec Genet 4 1995 237
29. J.T. Hare J.H. Taylor One role for DNA methylation in vertebrate cells is strand discrimination in mismatch repair Proc Natl Acad Sci USA 82 1985 7350
30. M.T. Hawn A. Umar J.M. Carethers Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint Cancer Res 55 1995 3721
31. N.M. Hollingsworth L. Ponte C. Halsey MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair Genes Dev 9 1995 1728
32. J. Holmes S. Clark P. Modrich Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines Proc Natl Acad Sci USA 87 1990 5837
33. Y. Ionov M.A. Peinado S. Malkhosyan Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis Nature 363 1993 558
34. J. Jiricny Colon cancer and DNA repair: Have mismatches met their match? Trends Genet 10 1994 164
35. P. Karran M. Bignami Self-destruction and tolerance in resistance of mammalian cells to alkylation damage Nucl Acids Res 20 1992 2933
36. 6-methylguanine residues in E. coli DNA Nature 296 1982 868
37. A. Kat W.G. Thilly Fang W.-H. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair Proc Natl Acad Sci USA 90 1993 6424
38. H. Katabuchi van Rees B. A.R. Lambers Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas Cancer Res 55 1995 5556
39. Knudson A.G. Jr Hereditary cancer, oncogenes, and antioncogenes Cancer Res 45 1985 1437
40. M. Koi A. Umar D.P. Chauhan Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation Cancer Res 54 1994 4308
41. R.D. Kolodner N.R. Hall J. Lipford Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations Genomics 24 1994 516
42. R.D. Kolodner N.R. Hall J. Lipford Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations Cancer Res 55 1995 242
43. W. Kramer B. Kramer M.S. Williamson Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: Homology of PMS1 to prokaryotic MutL and HexB J Bacteriol 171 1989 5339
44. T.A. Kunkel Misalignment-mediated DNA synthesis errors Biochemistry 29 1990 8003
45. R.S. Lahue K.G. Au P. Modrich DNA mismatch correction in a defined system Science 245 1989 160
46. F. Langle-Rouault M.G. Maenhaut M. Radman GATC sequences, DNA nicks and the MutH function in Escherichia coli mismatch repair EMBO J 6 1987 1121
47. V. Lazar S. Grandjouan C. Bognel Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patients Hum Molec Genet 3 1994 2257
48. F.S. Leach N.C. Nicolaides N. Papadopoulos Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer Cell 75 1993 1215
49. G. Levinson G.A. Gutman High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 in Escherichia coli K-12 Nucl Acids Res 15 1987 5323
50. G.-M. Li P. Modrich Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs Proc Natl Acad Sci USA 92 1995 1950
51. A. Lindblom P. Tannergard B. Werelius Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer Nature Genet 5 1993 279
52. B. Liu S.M. Farrington G.M. Petersen Genetic instability occurs in the majority of young patients with colorectal cancer Nature Med 1 1995 348
53. B. Liu N.C. Nicolaides S. Markowitz Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability Nature Genet 9 1995 48
54. B. Liu R.E. Parsons S.R. Hamilton hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds Cancer Res 54 1994 4590
55. B. Liu R. Parsons N. Papadopoulos Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer Nature Med 2 1996 169
56. L.A. Loeb Mutator phenotype may be required for multistage carcinogenesis Cancer Res 51 1991 3075
57. M.C. Luce G. Marra D.P. Chauhan In vitro transcription/translation assay for the screening of hMLH1 and hMSH2 mutations in familial colon cancer Gastroenterology 109 1995 1368
58. Y.K. Maliaka A.P. Chudina N.F. Belev CpG dinucleotides in the hMSH2 and hMLH1 genes are hotspots for HNPCC mutations Hum Genet 97 1996 251
59. S. Markowitz J. Wang L. Myeroff Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability Science 268 1995 1336
60. G. Marra C.R. Boland Hereditary nonpolyposis colorectal cancer: The syndrome, the genes, and historical perspectives J Natl Cancer Inst 87 1995 1114
61. G.T. Marsischky N. Filosi M.F. Kane Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair Genes Dev 10 1996 407
62. Mary J.-L. T. Bishop R. Kolodner Mutational analysis of the hMSH2 gene reveals a three base pair deletion in a family predisposed to colorectal cancer development Hum Molec Genet 3 1994 2067
63. P. Modrich Mismatch repair, genetic stability and tumour avoidance Phil Trans R Soc Lond B 347 1995 89
64. L. New K. Liu G.F. Crouse The yeast gene MSH3 defines a new class of eukaryotic MutS homologues Molec Gen Genet 239 1993 97
65. N.C. Nicolaides N. Papadopoulos B. Liu Mutations of two PMS homologues in hereditary nonpolyposis colon cancer Nature 371 1994 75
66. M. Nystrom-Lahti P. Kristo N.C. Nicolaides Founding mutations and Alu-mediated recombination in hereditary colon cancer Nature Med 1 1995 1203
67. F. Palombo P. Gallinari I. Iaccarino GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells Science 268 1995 1912
68. N. Papadopoulos F.S. Leach K.W. Kinzler Monoallelic mutation analysis (MAMA) for identifying germline mutations Nature Genet 11 1995 99
69. N. Papadopoulos N.C. Nicolaides B. Liu Mutations in GTBP in genetically unstable tumors Science 268 1995 1915
70. N. Papadopoulos N.C. Nicolaides Y.F. Wei Mutation of a mutL homolog in hereditary colon cancer Science 263 1994 1625
71. R. Parsons Li G.-M. M. Longley Mismatch repair deficiency in phenotypically normal human cells Science 268 1995 738
72. M.A. Peinado S. Malkhosyan Velazquez Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction Proc Natl Acad Sci USA 89 1992 10065
73. P. Peltomaki L.A. Aaltonen P. Sistonen Genetic mapping of a locus predisposing to human colorectal cancer Science 260 1993 810
74. TA Prolla, A requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of bacterial MutL. Ph.D. thesis. New Haven, Yale University
75. T.A. Prolla D.M. Christie R.M. Liskay Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene Molec Cell Biol 14 1994 407
76. T.A. Prolla Q. Pang E. Alani MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast Science 265 1994 1091
77. C. Rayssiguier D.S. Thaler M. Radman The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants Nature 342 1989 396
78. R.A.G. Reenan R.D. Kolodner Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins Genetics 132 1992 963
79. J.I. Risinger A. Berchuck M.F. Kohler Genetic instability of microsatellites in endometrial carcinoma Cancer Res 53 1993 5100
80. R. Sankila L.A. Aaltonen H.J. Jarvinen Better survival rates in patients with MLH1-associated hereditary colorectal cancer Gastroenterology 110 1996 682
81. 6-methylguanine in DNA to inactivation by alkylating agents including chloronitrosoureas Cancer Res 44 1984 2467
82. E.M. Selva L. New G.F. Crouse Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae. Genetics 139 1995 1175
83. D. Shibata M.A. Peinado Y. Ionov Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation Nature Genet 6 1994 273
84. M. Strand M.C. Earley G.F. Crouse Mutations in the MSH3 gene preferentially lead to deletions within tracts of single repetitive DNA in Saccharomyces cerevisiae Proc Natl Acad Sci USA 92 1995 10418
85. M. Strand T.A. Prolla R.M. Liskay Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair Nature 365 1993 274
86. P. Tannergard J.R. Lipford R. Kolodner Mutation screening in the hMLH1 gene in Swedish hereditary nonpolyposis colon cancer families Cancer Res 55 1995 6092
87. S.N. Thibodeau G. Bren D. Schaid Microsatellite instability in cancer of the proximal colon Science 260 1993 816
88. D.C. Thomas J.D. Roberts T.A. Kunkel Heteroduplex repair in extracts of human HeLa cells J Biol Chem 266 1991 3744
89. A. Umar J.C. Boyer T.A. Kunkel DNA loop repair by human cell extracts Science 266 1994 814
90. H.F.A. Vasen J.-P. Mecklin Meera Khan P. The International Collaborative Group on Hereditary Non-polyposis Colorectal Cancer Dis Colon Rect 34 1991 424
91. B. Vogelstein E.R. Fearon S.E. Kern Allelotype of colorectal carcinomas Science 244 1989 207
92. G.C. Walker Mutagenesis and inducible responses to deoxynucleotide damage in Escherichia coli Microbiol Rev 48 1984 60
93. J. Wijnen Meera Khan P. H. Vasen Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16 Am J Hum Genet 58 1996 300
94. J. Wijnen H. Vasen Meera Khan P. Seven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresis Am J Hum Genet 56 1995 1060
95. L. Xia W. Shen F. Ritacca A truncated hMSH2 transcript occurs as a common variant in the population: Implications for genetic diagnosis Cancer Res 56 1996 2289