Evidence of a butterfly-like configuration of structurally diverse allosteric inhibitors of the HIV-1 reverse transcriptase

Drug Design and Discovery

Volumn 14, Issue 3, 1996, Pages 241-257

  Mager, Peter P ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Allosteric receptor sites; Butterfly like shape; Canonical correlation; HIV 1 reverse transcriptase; Molecular modelling; Nonsubstrate (nonnucleoside) reverse transcriptase inhibitors (NNRTIs)

Indexed keywords

RNA DIRECTED DNA POLYMERASE INHIBITOR;

ARTICLE; BINDING AFFINITY; DRUG CONFORMATION; DRUG RESISTANCE; DRUG STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR MODEL; PHYSICAL CHEMISTRY;

ANTIVIRAL AGENTS; CHEMISTRY, PHYSICAL; HIV-1 REVERSE TRANSCRIPTASE; KINETICS; MOLECULAR CONFORMATION; NUCLEOSIDES; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030459744     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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