Transition-State Stabilization by Adenosine Deaminase: 1,6-Addition of Water to Purine Ribonucleoside, the Enzyme's Affinity for 6-Hydroxy-1,6-dihydropurine Ribonucleoside, and the Effective Concentration of Substrate Water at the Active Sitet

Biochemistry

Volumn 28, Issue 3, 1989, Pages 1242-1247

  Jones, Walda ^a,b   Kurz, Linda C ^a,b   Wolfenden, Richard ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; NEBULARINE;

ENZYME ACTIVE SITE; ENZYME INHIBITION; INHIBITION KINETICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

ADENOSINE DEAMINASE; BINDING SITES; ENZYME STABILITY; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOSIDE DEAMINASES; PURINE NUCLEOSIDES; RIBONUCLEOSIDES; SPECTROPHOTOMETRY, ULTRAVIOLET; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; WATER;

EID: 0024508458     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00429a043     Document Type: Article

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