Ultrastructural localization of carcinoembryonic antigen (CEA) glycoproteins and epithelial membrane antigen (EMA) in normal and neoplastic sweat glands

Journal of Cutaneous Pathology

Volumn 23, Issue 6, 1996, Pages 518-529

  Metze, D ^a   Luger, T A ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; EPITHELIAL MEMBRANE ANTIGEN; GLYCOPROTEIN;

ARTICLE; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL ULTRASTRUCTURE; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; IMMUNOGOLD STAINING; IMMUNOREACTIVITY; MICROVILLUS; MUCOUS CELL; PAGET SKIN DISEASE; SKIN METASTASIS; SWEAT GLAND TUMOR;

ADULT; CA-15-3 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CELL DIFFERENTIATION; HUMANS; PAGET'S DISEASE, EXTRAMAMMARY; SKIN NEOPLASMS; SWEAT GLAND NEOPLASMS; SWEAT GLANDS;

EID: 0030451480     PISSN: 03036987     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0560.1996.tb01444.x     Document Type: Article

References (51)

1. Thomas P, Toth CA, Saini KS, Jessup M, Steele G. The structure, metabolism and function of the carcinoembryonic antigen gene family. Biochim Biophys Acta 1990: 1032: 177.
2. Thompson JA, Grunert F, Zimmermann W. Carcinoembryonic antigen gene family: molecular biology and clinical perspectives. J Clin Lab Anal 1991: 5: 344.
3. Heyderman E, Steele K, Ormerod MG. A new antigen on the epithelial membrane: its immunoperoxidase localisation in normal and neoplastic tissue. J Clin Pathol 1979: 32: 35.
4. Sloane JP, Ormerod MG. Distribution of epithelial membrane antigen in normal and neoplastic tissues and its value in diagnostic tumor pathology. Cancer 1981: 47: 1786.
5. Pinkus GS, Kurtin PJ. Epithelia membrane antigen-a diagnostic discrimination in surgical pathology. Hum Pathol 1985: 16: 929.
6. Penneys NS. Immunohistochemistry of adnexal neoplasms. J Cutan Pathol 1984: 11: 357.
7. Eto H, Nishiyama S. Sweat gland cells. In: Hiroaki U, Hideo Y, eds. A colour atlas of dermato-immunohistocytology. Wolfe Medical Publications Ltd., 1989: 40.
8. Metze D, Bhardwaj R, Amann U, et al. Glycoproteins of the carcinoembryonic antigen (CEA) family are expressed in sweat and sebaceous glands of human fetal and adult skin. J Invest Dermatol 1996: 106: 64.
9. Metze D, Grunert F, Neumaier M, et al. Neoplasms with sweat gland differentiation express various glycoproteins of the carcinoembryonic antigen (CEA) family. J Cutan Pathol 1996: 23: 1.
10. Heyderman E, Strudley I, Powell G, et al. A new monoclonal antibody to epithelial membrane antigen (EMA) - E29. A comparison of its immunocytochemical reactivity with polyclonal anti-EMA antibodies and with another monoclonal antibody, HMFG-2. Br J Cancer 1985: 52: 355.
11. Cordel J, Richardson TC, Pulford KAF, et al. Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry. Br J Cancer 1985: 52: 347.
12. Heyderman E, Graham RM, Chapman DV, et al. Epithelial markers in primary skin cancer: an immunoperoxidase study of the distribution of epithelial membrane antigen (EMA) and carcinoembryonic antigen (CEA) in 65 primary skin carcinomas. Histopathology 1984: 8: 423.
13. Cotton DWK. Immunohistochemical staining of normal sweat glands. Br J Dermatol 1986: 114: 441.
14. Graham RM, McKee PH, Chapman DV, et al. Intercellular canaliculi in eccrine sweat glands: an immunoperoxidase study. Br J Dermatol 1985: 112: 397.
15. Noda Y, Horike H, Watanabe Y, Mori M, Tsujimura T. Immunohistochemical identification of epithelial membrane antigen in sweat gland tumors by the use of a monoclonal antibody. Pathol Res Pract 1987: 182: 797.
16. Kariniemi AL, Forsman LM, Wahlström T, et al. Expression of differentiation antigens in benign sweat gland tumours. Br J Dermatol 1984: 111: 175.
17. Swanson PE, Cherwitz DL, Neumann MP, Wick MR. Eccrine sweat gland carcinoma: an histologic and immunohistochemical study of 32 cases. J Cutan Pathol 1987: 14: 65.
18. Lever WT, Schaumburg-Lever G. Histopathology of the skin. 7th edn. Philadelphia: J.B. Lippincott Company, 1989.
19. Weedon D. Tumours of cutaneous appendages. In: Symmers WSC, ed. Systemic Pathology, vol 9, The skin. Edingburgh, London: Churchill Livingstone, 1992: 817.
20. Abenoza P, Ackerman AB. Neoplasms with eccrine differentiation. Philadelphia, New York: Lea & Febiger, 1990.
21. Warkel RL. Selected apocrine neoplasms. J Cutan Pathol 1984: 11: 437.
22. Grunert F, AbuHarfeil N, Schwarz K, et al. Two CEA and three NCA species, although distinguishable by monoclonal antibodies, have nearly identical peplide patterns. Int J Cancer 1985: 36: 357.
23. Nap M, ten Hoor KA, Fleuren GJ. Cross-reactivity with normal antigens in commercial anti-CEA sera, used for immunohistology. The need for tissue controls and absorption. Am J Clin Pathol 1983: 79: 25.
24. Metze D, Soyer H-P, Zeiger B, et al. Expression of a glycoprotein of the carcinoembryonic antigen (CEA) family in normal and neoplastic sebaceous glands - limited role of CEA as a sweat gland marker. J Am Acad Dermatol, 1996: 34: 735.
25. Romano EL, Romano M. Staphylococcal protein A bound to colloidal gold: a useful reagent to label antigen-antibody sites in electron microscopy. Immunohistochemistry 1977: 14: 711.
26. Kurosumi K, Shibasaka S, Ito T. Cytology of the secretion in mammalian sweat glands. Int Rev Cytol 1984: 87: 253.
27. Maiorana A, Nigrisoli E, Papotti M. Immunohistochemical markers of sweat gland tumors. J Cutan Pathol 1986: 13: 87.
28. Hassab-El-Naby HM, Tam S, White WL, Ackerman AB. Mixed tumors of the skin. Am J Dermatopathol 1989: 11: 413.
29. Metzler G, Schaumburg-Lever G, Liebig K. Ultrastructural localization of keratin and alpha-L-fucose in human eccrine sweat glands. Arch Dermatol Res 1990: 282: 12.
30. Schaumburg-Lever G, Metzler G, Tronnier M. Ultrastructural localization of lectin-binding sites in normal human eccrine and apocrine glands. J Dermatol Science 1991: 2: 55.
31. Sato K, Kang WH, Saga K, Sato KT. Biology of sweat glands and their disorders. I. Normal sweat gland function. J Am Acad Dermatol 1989: 20: 537.
32. Benchimol S, Fuks A, Jothy S, Beauchemin N, Shirota K, Stanners CP. Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule. Cell 1989: 57: 327.
33. Hashimoto K, Gross BG, Lever WF. Electron microscopic study of apocrine secretion. J Invest Dermatol 1966: 46: 378.
34. Thompson J, Zimmermann W. The carcinoembryonic antigen gene family: structure, expression and evolution. Tumor Biol 1988: 9: 63.
35. Baranov V, Yeung MMW, Hammarström S. Expression of carcinoembryonic antigen and nonspecific cross-reacting 50-kDa antigen in human normal and cancerous colon mucosa: Comparative ultrastructural study with monoclonal antibodies.Cancer Res 1994: 54: 3305.
36. Hashimoto K, Gross BG, Lever WT. The ultrastructure of the skin of human embryos. I. The intraepidermal eccrine sweat duct. J Invest Dermatol 1965: 45:139.
37. Hashimoto K, Gross BG, Lever WF. The ultrastructure of the skin of human embryos. II. The formation of intradermal portion of the eccrine sweat duct and of the secretory segment during the first half of embryonic life. J Invest Dermatol 1966: 46: 513.
38. Holbrook KA. Structure and function of the developing human skin. In: Goldsmith LA, ed. Physiology, biochemistry, and molecular biology of the skin. Oxford: Oxford University Press, 1991: 63.
39. Hashimolo K, Kanzaki T. Appendage tumors of the skin: histogenesis and ultrastructure. J Cutan Pathol 1984: 11: 365.
40. Sloane JP, Ormerod MG, Carter RL, Gusterson BA, Foster CS. An immunocytochemical study of the distribution of epithelial memebrane antigen in normal and disordered squamous epithelium. Diagn Histopathol 1982: 5: 11.
41. Metze D, Bhardwaj R, Amann U, Artuc M, Grunert F, Luger T. Carcinoembryonic antigen (CEA): an adhesion molecule of the skin? In: Ishibashi Y, Nakagawa H, Suzuki H, eds. Electron microscopy in dermatology - basic and clinical research. Amsterdam: Elsevier Science B.V., 1994: 249.
42. Caputo R, Califano A. Ultrastructural features of extramammary Paget's disease. Arch Clin Exp Dermatol 1970: 236: 121.
43. Furukawa F, Kashihara M, Miyauchi H, Yamabe H, Hamashima Y, Imamura S. Evaluation of carcinoembryonic antigen in extramammary Paget's disease. J Cutan Pathol 1984: 11: 558.
44. Sitakalin C, Ackerman AB. Mammary and extramammary Paget's disease. Am J Dermatopathol 1985: 7: 335.
45. Jones RE, Austin C, Ackerman AB. Extramammary Paget's disease. Am J Dermatopathol 19979: 1: 101.
46. Ebner H. Zur Ultrastruktur der Morbus Paget mamillae. Zschr Haut-Geschl-Krkh 1969: 44: 297.
47. Guarner S, Cohen C, DeRose PB. Histogenesis of extramammary and mammary Paget cells. Am J Dermatopathol 1989: 11: 313.
48. Helm KF, Goellner JR, Peters MS. Immunohistochemical stains in extramammary Paget's disease. Am J Dermatopathol 1992: 14: 402.
49. Imam A, Yoshida SO, Taylor CR. Distinguishing tumour cells of mammary from extramammary Paget's disease using antibodies to two different glycoproteins from human milk-fat-globule membrane. Br J Cancer 1988: 58: 373.
50. Vanstapel MJ, Gatter KC, De Wolf-Peeters C, Millard PR, Desmet VJ, Mason DY. Immunohistochemical study of mammary and extramammary Paget's disease. Histopathology 1984: 8: 1013.
51. Ahnen D, Nakane PK, Brown WR. Ultrastructural localization of carcinoembryonic antigen in normal and colon cancer. Cancer 1982: 49: 2077.