Expression of a glycoprotein of the carcinoembryonic antigen family in normal and neoplastic sebaceous glands: Limited role of carcinoembryonic antigen as a sweat gland marker

Journal of the American Academy of Dermatology

Volumn 34, Issue 5 I, 1996, Pages 735-744

  Metze, Dieter ^a   Soyer, H Peter ^b   Zelger, Bernhard ^c   Neumaier, Michael ^e   Grunert, Fritz ^f   Hartig, Christine ^d   Amann, Udo ^a   Bhardwaj, Ranjit ^a   Wagener, Christoph ^e   Luger, Thomas A ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF GRAZ   (Austria)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d KLINIKUM MINDEN   (Germany)

^e UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^f UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CROSS REACTING ANTIGEN; EPITHELIAL MEMBRANE ANTIGEN; GLYCOPROTEIN; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; FETUS; HAMARTOMA; HUMAN; HUMAN TISSUE; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; SEBACEOUS CARCINOMA; SEBACEOUS GLAND TUMOR;

EID: 15844393660     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0190-9622(96)90005-5     Document Type: Article

References (46)

1. Thompson J, Zimmermann W. The carcinoembryonic antigen gene family:structure, expression and evolution. Tumour Biol 1988;9:63-83.
2. Thomas P, Toth CA, Saini KS, et al. The structure, metabolism, and function of the carcinoembryonic antigen gene family. Biochem Biophys Acta 1990;1032:177-89.
3. Thompson JA, Grunert F, Zimmermann W. Carcinoembryonic antigen gene family: molecular biology and clinical perspectives. J Clin Lab Anal 1991;5:344-66.
4. Beauchemin N, Turbide C, Afar D, et al. A mouse analogue of the human carcinoembryonic antigen. Cancer Res 1989; 49:2017-21.
5. Katz AM, Rosenthal D, Sauder DN. Cell adhesion molecules: structure, function, and implication in a variety of cutaneous and other pathologic conditions. Int J Dermatol 1991;30:153-60.
6. Eto H, Nishiyama S. Sweat gland cells. In: Hiroaki U, Hideo Y, eds. A colour atlas of dermato-immunohistocytology. Tokyo: Wolfe Medical Publications, 1989:40-1.
7. Penneys NS, Nadji M, McKinney EC. Carcinoembryonic antigen present in human eccrine sweat. J AM ACAD DERMATOL 1981;4:401-3.
8. Cotton DWK. Immunohistochemical staining of normal sweat glands. Br J Dermatol 1986;114:441-9.
9. Graham RM, McKee PH, Chapman DV, et al. Intercellular canaliculi in eccrine sweat glands: an immunoperoxidase study. Br J Dermatol 1985;112:397-403.
10. Penneys NS. Immunohistochemistry of adnexal neoplasms. J Cutan Pathol 1984;11:357-64.
11. Kariniemi AL, Forsman LM, Wahlström T, et al. Expression of differentiation antigens in benign sweat gland tumours. Br J Dermatol 1984;111:175-82.
12. Penneys NS, Nadji M, Morales A. Carcinoembryonic antigen in benign sweat gland tumors. Arch Dermatol 1982; 118:225-7.
13. Penneys NS, Nadji M, Ziegels-Weissmann J, et al. Carcinoembryonic antigen in sweat gland carcinomas. Cancer 1982;50:1608-11.
14. Maiorana A, Nigrisoli E, Papotti M. Immunohistochemical markers of sweat gland tumors. J Cutan Pathol 1986; 13:187-96.
15. Metze D, Bhardwaj R, Amann U, et al. Glycoproteins of the carcinoembryonic antigen (CEA) family are expressed in sweat and sebaceous glands of human fetal and adult skin. J Invest Dermatol 1996;106:64-9.
16. 15a. Metze D, Grunert F, Neumaier M, et al. Neoplasms with sweat gland differentiation express various glycoproteins of the carcinoembryonic antigen (CEA) family. J Cutan Pathol 1996;23:1-11.
17. Heyderman E, Graham RM, Chapman DV, et al. Epithelial markers in primary skin cancer: an immunoperoxidase study of the distribution of epithelial membrane antigen (EMA) and carcinoembryonic antigen (CEA) in 65 primary skin carcinomas. Histopathology 1984;8:423-34.
18. Friedman KJ, Boudreau S, Farmer ER. Superficial epithelioma with sebaceous differentiation. J Cutan Pathol 1987;14:193-7.
19. Sloane JP, Ormerod MG. Distribution of epithelial membrane antigen in normal and neoplastic tissues and its value in diagnostic tumor pathology. Cancer 1981;47:1786-95.
20. Steffen CH, Ackerman AB, eds. Neoplasms with sebaceous differentiation. Philadelphia: Lea & Febiger, 1994.
21. Ackerman AB, de Viragh PA, Chongchitnant N, eds. Neoplasms with follicular differentiation. Philadelphia: Lea & Febiger, 1993.
22. Weedon D. Tumours of cutaneous appendages. In: Symmers WSC, ed. Systemic pathology: the skin; vol 9. Edinburgh: Churchill-Livingstone, 1992:817-72.
23. Brownstein MH, Shapiro L. The pilosebaceous tumors. Int J Dermatol 1977;16:340-52.
24. Prioleau PG, Santa Cruz DJ. Sebaceous gland neoplasia. J Cutan Pathol 1984;11:396-414.
25. Troy JL, Ackerman AB. Sebaceoma: a distinctive benign neoplasm of adnexal epithelium differentiating towards sebaceous cells. Am J Dermatopathol 1984;6:7-13.
26. Wick MR, Goellner JR, Wolfe JT, et al. Adnexal carcinomas of the skin: II. extraocular sebaceous carcinomas. Cancer 1985;56:1163-72.
27. Nelson BR, Hamlet KR, Gillard M, et al. Sebaceous carcinoma. J AM ACAD DERMATOL 1995;33:1-15.
28. Grunert F, Abu Harfeil N, Schwarz K, et al. Two CEA and three NCA species, although distinguishable by monoclonal antibodies, have nearly identical peptide patterns. Int J Cancer 1985;36:357-62.
29. Daniel S, Nagel G, Johnson JB, et al. Determination of the specificities of monoclonal antibodies recognizing members of the CEA family using a panel of transfectants. Int J Cancer 1993;55:303-10.
30. Drzeniek Z, Lamerz R, Fenger U, et al. Identification of membrane antigens in granulocytes and colonic carcinoma cells by a monoclonal antibody specific for biliary glycoprotein, a member of the carcinoembryonic antigen family. Cancer Lett 1991;56:173-6.
31. Nap M, ten Hoor KA, Fleuren GJ. Cross-reactivity with normal antigens in commercial anti-CEA sera, used for immunohistology: the need for tissue controls and absorption. Am J Clin Pathol 1983;79:25-31.
32. Hammarstrom S, Shively JE, Paxton RJ, et al. Antigenic sites in carcinoembryonic antigen. Cancer Res 1989;49: 4852-8.
33. Grunert F, Soubt M, Jantscheff P, et al. Specificity and epitope localization of CD 66/67 monoclonal antibodies. In: Schlossmann Sf, Boumsell L, Gilks W, et al, eds. Leukocyte typing V. White cell differentiation antigens. Oxford: Oxford Press. (in press)
34. Heyderman E, Strudley I, Powell G, et al. A new monoclonal antibody to epithelial membrane antigen (EMA)-E29: a comparison of its immunocytochemical reactivity with polyclonal anti-EMA antibodies and with another monoclonal antibody, HMFG-2. Br J Cancer 1985;52:355-61.
35. Lucocq JM, Roth J. Colloidal gold and colloidal silver-metallic markers for light microscopic histochemistry. In: Bullock GR, Petrusz P, eds. Techniques in immunocytochemistry; vol 3. New York: Academic Press, 1985:203-36.
36. Romano EL, Romano M. Staphylococcal protein A bound to colloidal gold: a useful reagent to label antigen-antibody sites in electron microscopy. Immunohistochemistry 1977;14:711-5.
37. Heyderman E, Steele K, Ormerod MG. A new antigen on the epithelial membrane: its immunoperoxidase localisation in normal and neoplastic tissue. J Clin Pathol 1979; 32:35-9.
38. Thompson J, Mössinger S, Reichardt V, et al. A polymerase-chain-reaction assay for the specific identification of transcripts encoded by individual CEA gene family members. Int J Cancer 1993;55:311-9.
39. Steffen CH. Mantleoma. Am J Dermatopathol 1993; 15:306-10.
40. Ormerod MG, Steele K, Westwood JH, et al. Epithelial membrane antigen:partial purification assay and properties. Br J Cancer 1983;48:533-41.
41. Strauss JS, Downing DT, Ebling FJ, et al. Sebaceous glands. In: Goldsmith LA, ed. Physiology, biochemistry, and molecular biology of the skin. Oxford: Oxford University Press, 1991:712-40.
42. Bell M. A comparative study of the ultrastructure of the sebaceous glands of man and other primates. J Invest Dermatol 1974;62:132-43.
43. Rothenberg J, Lambert WC, Vail JT Jr, et al. The Muir-Torre (Torre's) syndrome: the significance of a solitary sebaceous tumor. J AM ACAD DERMATOL 1990;23: 638-40.
44. Banse-Kupin L, Morales A, Barlow M. Torre's syndrome: report of two cases and review of the literature. J AM ACAD DERMATOL 1984;10:803-17.
45. Cohen PR, Kohn SR, Kurzrock R. Association of sebaceous gland tumors and internal malignancy: the Muir-Torre syndrome. Am J Med 1990;90:606-13.
46. Schwartz RA, Torre DP. The Muir-Torre syndrome: a 25-year retrospect. J AM ACAD DERMATOL 1995;33:90-104.