Selective enhancement of antagonist ligand binding at muscarinic M2 receptors by heparin due to receptor uncoupling

European Journal of Pharmacology

Volumn 296, Issue 1, 1996, Pages 113-118

  Wang, Shou Zhen ^a   Edmundson, Randee ^a   Zhu, Sheng Zu ^a   El Fakahany, Esam E ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Allosteric interaction; Heparin; Muscarinic receptor; Receptor coupling; Receptor subtype; Transfected cell

Indexed keywords

ATROPINE; GUANINE NUCLEOTIDE BINDING PROTEIN; HEPARIN; METHYLSCOPOLAMINE; MUSCARINIC M2 RECEPTOR; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PERTUSSIS TOXIN; RADIOLIGAND; RECEPTOR SUBTYPE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; DRUG SELECTIVITY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 0030033967     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00674-5     Document Type: Article

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