Avian and human homologues of the P2Y1 receptor: Pharmacological, signaling, and molecular properties

Drug Development Research

Volumn 39, Issue 3-4, 1996, Pages 253-261

  Boyer, José L ^a   Schachter, Joel B ^a   Sromek, Susan M ^a   Kyle Palmer, R ^a   Jacobson, Kenneth A ^b   Nicholas, Robert A ^a   Harden, T Kendall ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

P2 receptor antagonist; P2Y; P2Y receptors; Phospholipase C; Receptor

Indexed keywords

ADENINE NUCLEOTIDE DERIVATIVE; INOSITOL PHOSPHATE; MEMBRANE RECEPTOR; PHOSPHOLIPASE C; PURINE P2 RECEPTOR;

ANIMAL CELL; CHICKEN; CONFERENCE PAPER; CONTROLLED STUDY; DRUG SCREENING; ERYTHROCYTE MEMBRANE; MOLECULAR CLONING; NONHUMAN; RECEPTOR BINDING; SEQUENCE HOMOLOGY; TURKEY (BIRD);

EID: 0030428129     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199611/12)39:3/4<253::AID-DDR4>3.0.CO;2-Q     Document Type: Article

References (34)

1. 2Y-purinoceptors. Mol Pharmacol 35:526-532.
2. 2-purinergie receptor agonists and guanine nucleotides. J Biol Chem 264:884-890.
3. 32P]3′-0-4-benzoyl)henzoyl ATP. J Biol Chem 265:13515-13520.
4. 2Y-purinergic receptor that inhibits adenylyl cyclase but does not activate phospholipase C. J Pharmacol Exp Ther 267:1140-1146.
5. 2Y-purinergic receptors. Br J Pharmacol 116:2611-2616.
6. 1-purinergic receptor. Mol Pharmacol 50:1323-1329.
7. 2Y-purinergic receptor agonists. Br J Pharmacol 118:1959-1964.
8. 2y-purinergic receptors. Br J Pharmacol 113:614-620.
9. 2Y subtypes. Drug Dev Res 31:206-219.
10. 2-purinoceptors? Gen Pharmacol 16:433-440.
11. 2 nucleotide receptor. J Biol Chem 270:26152-26158.
12. Communi D, Pirotton S, Parmentier M, Boeynaems JM (1995): Cloning and functional expression of a human uridine nucleotide receptor. J Biol Chem 270:30849-30852.
13. 2-purinergic receptor. J Biol Chem 264:6202-6206.
14. 2Y-purinergic receptor that couples to phospholipase C. Mol Pharmacol 46:8-14.
15. Fischer B, Boyer JL, Hoyle CHV, Ziganshin AU, Brizzolara AL, Knight CE, Zimmet J, Burnstock C, Harden TK, Jacobson KA (1993): Identification of potent, selective Pay-purinoceptor agonists: structure activity relationships (or 2-thioether derivatives of adenosine-5′-triphosphate. J Med Chem 36:3937-3946.
16. Harden TK, Hawkins FT, Stephens L, Boyer JL, Downes CP (1988): Phosphoinositide hydrolysis by guanosine 5′-0-(3-thiotriphosphate)-activated phospholipase C of turkey erythrocyte membranes. Biochem J 252:583-593.
17. 2-Puriuergic Receptors, ed by CA Weisman, J Turner, and J Fedan, Humana Press, in press.
18. Harden TK, Stephens L, Hawkins PT, Downes CP (1987): Turkey erythrocyte membranes as a model for regulation of phospholipase C by guanine nucleotides. J Biol Chem 262:9057-9061.
19. Lustig KO, Shiau AK, Brake AJ, Julius D (1993): Expression cloning of an ATP receptor from mouse neuroblastoma cells. Proc Natl Acad Sci USA 90:5113-5117.
20. 11 as the phospholipase C-activating G-protein of turkey erythrocytes. Biochem J 290:765-770.
21. 2Y-purinergic receptor and C-protein-mediated regulation of the purified enzyme. J Biol Chem 265:13508-13514.
22. Nguyen T, Erb L, Weismann CA, Marchese A, Heng HHQ, Garrad RC, George SR, Turner JT, O'Dowd BF (1995): Cloning, expression, and chromosomal localization of the human uridine micleotide receptor gene. J Biol Chem 270:30845-30848.
23. 2 receptors: Identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor. Mol Pharmacol 50:224-229.
24. North RA (1996): P2X purinoceptor plethora. Sem in Neurosci (In Press).
25. 16 couple a wide variety of receptors to phospholipase C. J Biol Chem 270:15175-15180.
26. Rooney TA, Hager R, Thomas AP (1991): β-adrenergic receptor-mediated phospholipase C activation independent of cAMP formation in turkey erythrocyte membranes. J Biol Chem 266:15068-15074.
27. 2Y-purinergic receptor. Br J Pharmacol 118:167-173.
28. 2Y purinoceptor. Eur J Pharmacol 291:281-289.
29. 2X receptors bring new structure to liquid-gated ion channels. TINS 18:224-229.
30. 2Y-purinergic receptors. Biochem J 284:917-922.
31. 4 and G-protein βγ-subunit-regulated phospholipase C-activating protein. J Biol Chem 261:14217-14225.
32. Waldo CL, Nicholas RA, Harden TK (1996): Molecular cloning and expression of a phospholipase β isoenzyme from avian erythrocytes. Biochem J 316:559-568.
33. 5. Biochem Biophys Res Commun 219:105-110.
34. Webb TE, Simon J, Krishek BJ, Bateson AN, Smart TG, King BF, Burnstock G, Barnard EA (1993): Cloning and functional expression of a brain G-protein-conpled ATP receptor. FEBS Lett 324:219-225.