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Volumn 365, Issue 1-3, 1996, Pages 161-173

Application of in vitro cell transformation assays to predict the carcinogenic potential of chemicals

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN;

EID: 0030250780     PISSN: 01651110     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1110(96)90019-6     Document Type: Article
Times cited : (31)

References (84)
  • 1
    • 0030596898 scopus 로고    scopus 로고
    • The low pH Syrian hamster embryo (SHE) cell transformation assay: A revitalized role in carcinogen prediction
    • in press
    • Aardema M.J., Isfort R.J., Thompson E.D., LeBoeuf R.A. The low pH Syrian hamster embryo (SHE) cell transformation assay: a revitalized role in carcinogen prediction. Mutation Res. 1996;. in press.
    • (1996) Mutation Res.
    • Aardema, M.J.1    Isfort, R.J.2    Thompson, E.D.3    LeBoeuf, R.A.4
  • 2
    • 0014348011 scopus 로고
    • Development of 3T3-like lines from BALB / c mouse embryo cultures: Transformation susceptibility to SV40
    • Aaronson S.A., Todaro G.J. Development of 3T3-like lines from BALB / c mouse embryo cultures: transformation susceptibility to SV40. J. Cell Physiol. 72:1968;141-148.
    • (1968) J. Cell Physiol. , vol.72 , pp. 141-148
    • Aaronson, S.A.1    Todaro, G.J.2
  • 3
    • 0014434443 scopus 로고
    • Basis for the acquisition of malignant potential by mouse cells cultivated in vitro
    • Aaronson S.A., Todaro G.J. Basis for the acquisition of malignant potential by mouse cells cultivated in vitro. Science. 162:1968a;1024-1026.
    • (1968) Science , vol.162 , pp. 1024-1026
    • Aaronson, S.A.1    Todaro, G.J.2
  • 4
    • 0000973407 scopus 로고
    • Definitive relationship among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP
    • Ashby J., Tennant R.W. Definitive relationship among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP. Mutation Res. 257:1991;229-306.
    • (1991) Mutation Res. , vol.257 , pp. 229-306
    • Ashby, J.1    Tennant, R.W.2
  • 5
    • 0021265381 scopus 로고
    • Use of cell transformation systems for carcinogenicity testing and mechanistic studies of carcinogens
    • Barrett J.C., Hesterberg T.W., Thomassen D.G. Use of cell transformation systems for carcinogenicity testing and mechanistic studies of carcinogens. Pharm. Rev. 36:1984;53S-70S.
    • (1984) Pharm. Rev. , vol.36
    • Barrett, J.C.1    Hesterberg, T.W.2    Thomassen, D.G.3
  • 7
    • 0000866282 scopus 로고
    • Cellular and molecular mechanisms of multistep carcinogenesis in cell culture models
    • Barrett J.C. Boca Raton, FL: CRC Press, Inc.
    • Barrett J.C. Cellular and molecular mechanisms of multistep carcinogenesis in cell culture models. Barrett J.C. Mechanisms of Environmental Carcinogenesis: Multistep Models of Carcinogenesis. Vol. 1:1987;129-142 CRC Press, Inc. Boca Raton, FL.
    • (1987) Mechanisms of Environmental Carcinogenesis: Multistep Models of Carcinogenesis , vol.1 , pp. 129-142
    • Barrett, J.C.1
  • 8
    • 0000866282 scopus 로고
    • Cellular and molecular mechanisms of multi-step carcinogenesis in cell culture models
    • Barrett J.C. Boca Raton, FL: CRC Press, Inc.
    • Barrett J.C., Fletcher W.F. Cellular and molecular mechanisms of multi-step carcinogenesis in cell culture models. Barrett J.C. Mechanisms of Environmental Carcinogenesis: Multistep Models of Carcinogenesis. Vol. 2:1987;73-116 CRC Press, Inc. Boca Raton, FL.
    • (1987) Mechanisms of Environmental Carcinogenesis: Multistep Models of Carcinogenesis , vol.2 , pp. 73-116
    • Barrett, J.C.1    Fletcher, W.F.2
  • 9
    • 0001283359 scopus 로고
    • In vitro transformation with chemical carcinogens
    • Berwald Y., Sachs L. In vitro transformation with chemical carcinogens. Nature. 200:1963;1182-1184.
    • (1963) Nature , vol.200 , pp. 1182-1184
    • Berwald, Y.1    Sachs, L.2
  • 10
    • 0026010995 scopus 로고
    • Molecular themes in oncogenesis
    • Bishop J.M. Molecular themes in oncogenesis. Cell. 64:1991;235-284.
    • (1991) Cell , vol.64 , pp. 235-284
    • Bishop, J.M.1
  • 11
    • 0025303739 scopus 로고
    • Genetic and cellular basis of multistep carcinogenesis
    • Boyd J.A., Barrett J.C. Genetic and cellular basis of multistep carcinogenesis. Pharmacol. Ther. 46:1990;469-486.
    • (1990) Pharmacol. Ther. , vol.46 , pp. 469-486
    • Boyd, J.A.1    Barrett, J.C.2
  • 12
    • 0024993136 scopus 로고
    • Consideration of both genotoxic and nongenotoxic mechanisms in predicting carcinogenic potential
    • Butterworth B.E. Consideration of both genotoxic and nongenotoxic mechanisms in predicting carcinogenic potential. Mutation Res. 239:1990;117-132.
    • (1990) Mutation Res. , vol.239 , pp. 117-132
    • Butterworth, B.E.1
  • 13
    • 0028287098 scopus 로고
    • N-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hrasl gene mutations
    • Cha R.S., Thilly W.G., Zarbl H. N-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hrasl gene mutations. Proc. Natl. Acad. Sci. USA. 91:1994;3749-3753.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3749-3753
    • Cha, R.S.1    Thilly, W.G.2    Zarbl, H.3
  • 14
    • 0025168534 scopus 로고
    • Cell proliferation in carcinogenesis
    • Cohen S.M., Ellwein L.B. Cell proliferation in carcinogenesis. Science. 249:1990;1007-1011.
    • (1990) Science , vol.249 , pp. 1007-1011
    • Cohen, S.M.1    Ellwein, L.B.2
  • 15
    • 0026025755 scopus 로고
    • Growth factors in development, transformation and tumorigenesis
    • Cross M., Dexter T.M. Growth factors in development, transformation and tumorigenesis. Cell. 64:1991;271-280.
    • (1991) Cell , vol.64 , pp. 271-280
    • Cross, M.1    Dexter, T.M.2
  • 16
    • 0015458712 scopus 로고
    • Quantitation of chemically-induced neoplastic transformation of BALB/3T3 cloned cell lines
    • DiPaolo J.A., Takano K., Popescu N.C. Quantitation of chemically-induced neoplastic transformation of BALB/3T3 cloned cell lines. Cancer Res. 32:1972;2686-2695.
    • (1972) Cancer Res. , vol.32 , pp. 2686-2695
    • DiPaolo, J.A.1    Takano, K.2    Popescu, N.C.3
  • 17
    • 0025978025 scopus 로고
    • Recommended protocols based on a survey of current practice in genotoxicity testing laboratories: III. Cell transformation in the C3H 10T1/2 mouse embryo cells, BALB/c 3T3 mouse fibroblasts and Syrian hamster embryo cell cultures
    • Dunkel V.C., Swiernga S.H.H., Brillinger R.L., Gilman J.P.W., Nestman E.R. Recommended protocols based on a survey of current practice in genotoxicity testing laboratories: III. Cell transformation in the C3H 10T1/2 mouse embryo cells, BALB/c 3T3 mouse fibroblasts and Syrian hamster embryo cell cultures. Mutation Res. 246:1991;285-300.
    • (1991) Mutation Res. , vol.246 , pp. 285-300
    • Dunkel, V.C.1    Swiernga, S.H.H.2    Brillinger, R.L.3    Gilman, J.P.W.4    Nestman, E.R.5
  • 18
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 61:1990;759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 19
    • 0028032651 scopus 로고
    • Clonal variation of tumorigenic potential in v-Ha-ras transformed human bronchial epithelial cells: Relationship to ras oncogene expression and CAD gene amplification
    • Forrester K., Kispert J., Sanchez J.H., Gerwin B.I., Tisty T.D., Harris C.C. Clonal variation of tumorigenic potential in v-Ha-ras transformed human bronchial epithelial cells: relationship to ras oncogene expression and CAD gene amplification. Mol. Carcinogen. 11:1994;34-41.
    • (1994) Mol. Carcinogen. , vol.11 , pp. 34-41
    • Forrester, K.1    Kispert, J.2    Sanchez, J.H.3    Gerwin, B.I.4    Tisty, T.D.5    Harris, C.C.6
  • 20
    • 0028922325 scopus 로고
    • Detection of aneuploidy-inducing carcinogens in the Syrian hamster embryo (SHE) cell transformation assay
    • Gibson D.P., Aardema M.J., Kerckaert G.A., Carr G.J., Brauninger R.M., LeBoeuf R.A. Detection of aneuploidy-inducing carcinogens in the Syrian hamster embryo (SHE) cell transformation assay. Mutation Res. 343:1995;7-24.
    • (1995) Mutation Res. , vol.343 , pp. 7-24
    • Gibson, D.P.1    Aardema, M.J.2    Kerckaert, G.A.3    Carr, G.J.4    Brauninger, R.M.5    LeBoeuf, R.A.6
  • 22
    • 0000496773 scopus 로고
    • Predicting rodent carcinogenicity from four in vitro genetic toxicity assays: An evaluation of 114 chemicals studied by the National Toxicology Program
    • Haseman J.K., Zeiger E., Shelby M.D., Margolin B.H., Tennant R.W. Predicting rodent carcinogenicity from four in vitro genetic toxicity assays: an evaluation of 114 chemicals studied by the National Toxicology Program. J. Am. Stat. Assoc. 85:1990;964-971.
    • (1990) J. Am. Stat. Assoc. , vol.85 , pp. 964-971
    • Haseman, J.K.1    Zeiger, E.2    Shelby, M.D.3    Margolin, B.H.4    Tennant, R.W.5
  • 23
    • 0028181684 scopus 로고
    • Malignant transformation of human bronchial epithelial cells by radon-simulated alpha particles
    • Hei T.K., Piao C.Q., Willey J.C., Thomas S., Hall E.J. Malignant transformation of human bronchial epithelial cells by radon-simulated alpha particles. Carcinogenesis. 15:1994;431-437.
    • (1994) Carcinogenesis , vol.15 , pp. 431-437
    • Hei, T.K.1    Piao, C.Q.2    Willey, J.C.3    Thomas, S.4    Hall, E.J.5
  • 26
    • 0021910240 scopus 로고
    • Induction by asbestos fibers of anaphase abnormalities: Mechanisms for aneuploidy induction and possibly carcinogenesis
    • Hesterberg T.W., Barrett J.C. Induction by asbestos fibers of anaphase abnormalities: mechanisms for aneuploidy induction and possibly carcinogenesis. Carcinogenesis. 6:1985;473-475.
    • (1985) Carcinogenesis , vol.6 , pp. 473-475
    • Hesterberg, T.W.1    Barrett, J.C.2
  • 28
    • 0029446471 scopus 로고    scopus 로고
    • The Syrian hamster embryo (SHE) cell transformation system: A biologically relevant in vitro model - with carcinogen predicting capabilities - of in vivo multistage neoplastic transformation
    • in press
    • Isfort R.J., LeBoeuf R.A. The Syrian hamster embryo (SHE) cell transformation system: a biologically relevant in vitro model - with carcinogen predicting capabilities - of in vivo multistage neoplastic transformation. Crit. Rev. Oncogen. 1996;. in press.
    • (1996) Crit. Rev. Oncogen.
    • Isfort, R.J.1    LeBoeuf, R.A.2
  • 29
    • 0026685689 scopus 로고
    • Two-dimensional gel electrophoresis analysis of Syrian hamster embryo cells: Morphological transformation is not cell type specific
    • Isfort R.J., Kerckaert G., Anderson N.L., LeBoeuf R.A. Two-dimensional gel electrophoresis analysis of Syrian hamster embryo cells: morphological transformation is not cell type specific. Electrophoresis. 13:1992;855-861.
    • (1992) Electrophoresis , vol.13 , pp. 855-861
    • Isfort, R.J.1    Kerckaert, G.2    Anderson, N.L.3    LeBoeuf, R.A.4
  • 30
    • 0027098906 scopus 로고
    • Phenotypic differences between Syrian hamster embryo cells cultured at pH 6.7 or 7.3
    • Isfort R.J., Cody D.B., Asquith T.N., LeBoeuf R.A. Phenotypic differences between Syrian hamster embryo cells cultured at pH 6.7 or 7.3. In vitro Cell. Dev. Biol. 28A:1992a;635-642.
    • (1992) In vitro Cell. Dev. Biol. , vol.28 , pp. 635-642
    • Isfort, R.J.1    Cody, D.B.2    Asquith, T.N.3    LeBoeuf, R.A.4
  • 31
    • 0027479225 scopus 로고
    • Induction of protein phosphorylation, protein synthesis, immediate early gene expression and cellular proliferation by intracellular pH modulation
    • Isfort R.J., Cody D.B., Asquith T.N., Ridder G.M., Stuard S.B., LeBoeuf R.A. Induction of protein phosphorylation, protein synthesis, immediate early gene expression and cellular proliferation by intracellular pH modulation. Eur. J. Biochem. 213:1993;349-357.
    • (1993) Eur. J. Biochem. , vol.213 , pp. 349-357
    • Isfort, R.J.1    Cody, D.B.2    Asquith, T.N.3    Ridder, G.M.4    Stuard, S.B.5    LeBoeuf, R.A.6
  • 32
    • 0028302758 scopus 로고
    • Growth factor responsiveness and alterations in growth factor homeostasis in Syrian hamster embryo cells during in vitro transformation
    • Isfort R.J., Cody D.B., Kerckaert G.A., LeBoeuf R.A. Growth factor responsiveness and alterations in growth factor homeostasis in Syrian hamster embryo cells during in vitro transformation. Carcinogenesis. 15:1994;1203-1209.
    • (1994) Carcinogenesis , vol.15 , pp. 1203-1209
    • Isfort, R.J.1    Cody, D.B.2    Kerckaert, G.A.3    LeBoeuf, R.A.4
  • 33
    • 0028137272 scopus 로고
    • Alterations in cellular differentiation, mitogenesis, cytoskeleton and growth characteristics during Syrian hamster embryo cell multistep in vitro transformation
    • Isfort R.J., Cody D.B., Doersen C.-J., Kerckaert G.A., LeBoeuf R.A. Alterations in cellular differentiation, mitogenesis, cytoskeleton and growth characteristics during Syrian hamster embryo cell multistep in vitro transformation. Int. J. Cancer. 59:1994a;114-125.
    • (1994) Int. J. Cancer , vol.59 , pp. 114-125
    • Isfort, R.J.1    Cody, D.B.2    Doersen, C.-J.3    Kerckaert, G.A.4    LeBoeuf, R.A.5
  • 34
    • 0030596895 scopus 로고    scopus 로고
    • Comparison of the standard and reduced pH Syrian hamster embryo (SHE) cell in vitro transformation assays to predict the carcinogenic potential of chemicals
    • in press
    • Isfort R.J., Kerckaert G.A., LeBoeuf R.A. Comparison of the standard and reduced pH Syrian hamster embryo (SHE) cell in vitro transformation assays to predict the carcinogenic potential of chemicals. Mutation Res. 1996a;. in press.
    • (1996) Mutation Res.
    • Isfort, R.J.1    Kerckaert, G.A.2    LeBoeuf, R.A.3
  • 35
    • 0029951999 scopus 로고    scopus 로고
    • Isolation and biological characterization of morphological transformation sensitive Syrian hamster embryo cells
    • in press
    • Isfort R.J., Kerckaert G.A., Cody D.B., Carter J., Driscoll K.E., LeBoeuf R.A. Isolation and biological characterization of morphological transformation sensitive Syrian hamster embryo cells. Carcinogenesis. 1996b;. in press.
    • (1996) Carcinogenesis
    • Isfort, R.J.1    Kerckaert, G.A.2    Cody, D.B.3    Carter, J.4    Driscoll, K.E.5    LeBoeuf, R.A.6
  • 36
    • 0029616002 scopus 로고    scopus 로고
    • Modulation of the platelet-derived growth factor induced calcium signal by extracellular/intracellular pH in Syrian hamster embryo cells
    • Isfort R.J., Stuard S.B., Cody D.B., Ridder G.M., LeBoeuf R.A. Modulation of the platelet-derived growth factor induced calcium signal by extracellular/intracellular pH in Syrian hamster embryo cells. Eur. J. Biochem. 234:1996c;801-810.
    • (1996) Eur. J. Biochem. , vol.234 , pp. 801-810
    • Isfort, R.J.1    Stuard, S.B.2    Cody, D.B.3    Ridder, G.M.4    LeBoeuf, R.A.5
  • 37
    • 85030267357 scopus 로고    scopus 로고
    • Morphological transformation in Syrian hamster embryo (SHE) cells results from a block in cellular differentiation mediated by the tumor suppressor gene H19
    • submitted
    • Isfort R.J., Cody D.B., Kerckaert G.A., Stuard S.B., Tycko B., Ridder G.M., LeBoeuf R.A. Morphological transformation in Syrian hamster embryo (SHE) cells results from a block in cellular differentiation mediated by the tumor suppressor gene H19. Proc. Natl. Acad. Sci. USA. 1996d;. submitted.
    • (1996) Proc. Natl. Acad. Sci. USA
    • Isfort, R.J.1    Cody, D.B.2    Kerckaert, G.A.3    Stuard, S.B.4    Tycko, B.5    Ridder, G.M.6    LeBoeuf, R.A.7
  • 39
    • 0015861335 scopus 로고
    • A quantitative system for assay of malignant transformation by chemical carcinogens using a clone derived from BALB/3T3
    • Kakunaga T. A quantitative system for assay of malignant transformation by chemical carcinogens using a clone derived from BALB/3T3. Int. J. Cancer. 12:1973;463-473.
    • (1973) Int. J. Cancer , vol.12 , pp. 463-473
    • Kakunaga, T.1
  • 40
    • 0028906079 scopus 로고
    • Human fibroblast (KMST-6/RAS cell line) transformed with 60Co gamma-rays and c-Ha-ras oncogene produce a large amount of granulocyte colony-stimulating factor (G-CSF); Production is enhanced by cAMC, theophylline, and butyrate
    • Kawashima K., Jahan I., Fushimi K., Mihara K., Namba M. Human fibroblast (KMST-6/RAS cell line) transformed with 60Co gamma-rays and c-Ha-ras oncogene produce a large amount of granulocyte colony-stimulating factor (G-CSF); production is enhanced by cAMC, theophylline, and butyrate. Cell Struct. Funct. 20:1995;41-45.
    • (1995) Cell Struct. Funct. , vol.20 , pp. 41-45
    • Kawashima, K.1    Jahan, I.2    Fushimi, K.3    Mihara, K.4    Namba, M.5
  • 41
    • 0028172581 scopus 로고
    • Effects of retinoids, beta-carotene, and canthaxanthin on UV and X-ray-induced transformation of C3H10T1/2 cells in vitro
    • Kennedy A.R., Krinsky N.I. Effects of retinoids, beta-carotene, and canthaxanthin on UV and X-ray-induced transformation of C3H10T1/2 cells in vitro. Nutr. Cancer. 22:1994;219-232.
    • (1994) Nutr. Cancer , vol.22 , pp. 219-232
    • Kennedy, A.R.1    Krinsky, N.I.2
  • 42
    • 0030596896 scopus 로고    scopus 로고
    • A comprehensive protocol for conducting the Syrian hamster embryo cell transformation assay at pH 6.70
    • in press
    • Kerckaert G.A., Isfort R.J., Carr G.J., Aardema M.J., LeBoeuf R.A. A comprehensive protocol for conducting the Syrian hamster embryo cell transformation assay at pH 6.70. Mutation Res. 1996;. in press.
    • (1996) Mutation Res.
    • Kerckaert, G.A.1    Isfort, R.J.2    Carr, G.J.3    Aardema, M.J.4    LeBoeuf, R.A.5
  • 43
    • 0029841726 scopus 로고    scopus 로고
    • Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays
    • in press
    • Kerckaert G.A., Brauninger R., LeBoeuf R.A., Isfort R.J. Use of the Syrian hamster embryo cell transformation assay for carcinogenicity prediction of chemicals currently being tested by the National Toxicology Program in rodent bioassays. Environ. Health Perspect. 1996a;. in press.
    • (1996) Environ. Health Perspect.
    • Kerckaert, G.A.1    Brauninger, R.2    LeBoeuf, R.A.3    Isfort, R.J.4
  • 44
    • 0029791458 scopus 로고    scopus 로고
    • PH effects on the lifespan and transformation frequency of Syrian hamster embryo (SHE) cells
    • submitted
    • Kerckaert G.A., LeBoeuf R.A., Isfort R.J. pH effects on the lifespan and transformation frequency of Syrian hamster embryo (SHE) cells. Carcinogenesis. 1996b;. submitted.
    • (1996) Carcinogenesis
    • Kerckaert, G.A.1    LeBoeuf, R.A.2    Isfort, R.J.3
  • 45
    • 0022777449 scopus 로고
    • The induction of transformed-like morphology and enhanced growth in Syrian hamster embryo cells grown at acidic pH
    • LeBoeuf R.A., Kerckaert G.A. The induction of transformed-like morphology and enhanced growth in Syrian hamster embryo cells grown at acidic pH. Carcinogenesis. 7:1986;1431-1440.
    • (1986) Carcinogenesis , vol.7 , pp. 1431-1440
    • LeBoeuf, R.A.1    Kerckaert, G.A.2
  • 46
    • 0023182776 scopus 로고
    • Enhanced morphological transformation of early passage Syrian hamster embryo cells cultured in medium with a reduced bicarbonate concentration and pH
    • LeBoeuf R.A., Kerckaert G.A. Enhanced morphological transformation of early passage Syrian hamster embryo cells cultured in medium with a reduced bicarbonate concentration and pH. Carcinogenesis. 8:1987;689-697.
    • (1987) Carcinogenesis , vol.8 , pp. 689-697
    • LeBoeuf, R.A.1    Kerckaert, G.A.2
  • 47
    • 0025302535 scopus 로고
    • Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.7
    • LeBoeuf R.A., Kerckaert G.A., Aardema M.J., Gibson D.P. Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.7. Cancer Res. 50:1990;3722-3729.
    • (1990) Cancer Res. , vol.50 , pp. 3722-3729
    • LeBoeuf, R.A.1    Kerckaert, G.A.2    Aardema, M.J.3    Gibson, D.P.4
  • 48
    • 0026503308 scopus 로고
    • Intracellular acidification is associated with enhanced morphological transformation in Syrian hamster embryo cells
    • LeBoeuf R.A., Lin P., Gruenstein E. Intracellular acidification is associated with enhanced morphological transformation in Syrian hamster embryo cells. Cancer Res. 52:1992;144-148.
    • (1992) Cancer Res. , vol.52 , pp. 144-148
    • LeBoeuf, R.A.1    Lin, P.2    Gruenstein, E.3
  • 49
    • 0030596897 scopus 로고    scopus 로고
    • The pH 6.7 Syrian hamster embryo cell transformation assay for assessing the carcinogenic potential of chemicals
    • in press
    • LeBoeuf R.A., Kerckaert G.A., Aardema M.J., Gibson D.P., Brauninger R., Isfort R.J. The pH 6.7 Syrian hamster embryo cell transformation assay for assessing the carcinogenic potential of chemicals. Mutation Res. 1996;. in press.
    • (1996) Mutation Res.
    • LeBoeuf, R.A.1    Kerckaert, G.A.2    Aardema, M.J.3    Gibson, D.P.4    Brauninger, R.5    Isfort, R.J.6
  • 50
    • 0022341366 scopus 로고
    • Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture
    • Lee T.C., Oshimura M., Barrett J.C. Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture. Carcinogenesis. 6:1985;1421-1426.
    • (1985) Carcinogenesis , vol.6 , pp. 1421-1426
    • Lee, T.C.1    Oshimura, M.2    Barrett, J.C.3
  • 51
    • 0026059515 scopus 로고
    • Tumor suppressor genes
    • Marshall C.J. Tumor suppressor genes. Cell. 64:1991;313-326.
    • (1991) Cell , vol.64 , pp. 313-326
    • Marshall, C.J.1
  • 52
    • 0027485609 scopus 로고
    • Transformation of BALB/c-3T3 cells: V. Transformation responses of 168 chemicals compared with mutagenicity in Salmonella and carcinogenicity in rodent bioassays
    • Matthews E.J., Spalding J.W., Tennant R.W. Transformation of BALB/c-3T3 cells: V. Transformation responses of 168 chemicals compared with mutagenicity in Salmonella and carcinogenicity in rodent bioassays. Environ. Health Perspect. 101:(Suppl. 2):1993;347-482.
    • (1993) Environ. Health Perspect. , vol.101 , Issue.SUPPL. 2 , pp. 347-482
    • Matthews, E.J.1    Spalding, J.W.2    Tennant, R.W.3
  • 53
    • 0027493090 scopus 로고
    • Transformation of BALB/c-3T3 cells: I. investigation of experimental parameters that influence detection of spontaneous transformation
    • Matthews E.J. Transformation of BALB/c-3T3 cells: I. investigation of experimental parameters that influence detection of spontaneous transformation. Environ. Health Perspect. 101:(Suppl. 2):1993a;277-291.
    • (1993) Environ. Health Perspect. , vol.101 , Issue.SUPPL. 2 , pp. 277-291
    • Matthews, E.J.1
  • 54
    • 0027422242 scopus 로고
    • Transformation of BALB/c-3T3 cells: II. Investigation of experimental parameters that influence detection of benzo[a]pyrene-induced transformation
    • Matthews E.J. Transformation of BALB/c-3T3 cells: II. Investigation of experimental parameters that influence detection of benzo[a]pyrene-induced transformation. Environ. Health Perspect. 101:(Suppl. 2):1993b;293-310.
    • (1993) Environ. Health Perspect. , vol.101 , Issue.SUPPL. 2 , pp. 293-310
    • Matthews, E.J.1
  • 55
    • 0027442571 scopus 로고
    • Transformation of BALB/c-3T3 cells: III. Development of a co-culture clonal survival assay for quantification of chemical cytotoxicity in high-density cell cultures
    • Matthews E.J. Transformation of BALB/c-3T3 cells: III. Development of a co-culture clonal survival assay for quantification of chemical cytotoxicity in high-density cell cultures. Environ. Health Perspect. 101:(Suppl. 2):1993c;311-318.
    • (1993) Environ. Health Perspect. , vol.101 , Issue.SUPPL. 2 , pp. 311-318
    • Matthews, E.J.1
  • 56
    • 0027521723 scopus 로고
    • Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure
    • Matthews E.J. Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure. Environ. Health Perspect. 101:(Suppl. 2):1993d;319-345.
    • (1993) Environ. Health Perspect. , vol.101 , Issue.SUPPL. 2 , pp. 319-345
    • Matthews, E.J.1
  • 57
    • 0024342568 scopus 로고
    • Malignant transformation of mammalian cells in culture including human cells
    • McCormick J.J., Maher V.M. Malignant transformation of mammalian cells in culture including human cells. Environ. Mol. Mutagenesis. 14:1989;105-113.
    • (1989) Environ. Mol. Mutagenesis , vol.14 , pp. 105-113
    • McCormick, J.J.1    Maher, V.M.2
  • 58
    • 0028319087 scopus 로고
    • Analysis of the multistep process of carcinogenesis using human fibroblasts
    • McCormick J.J., Maher V.M. Analysis of the multistep process of carcinogenesis using human fibroblasts. Risk Anal. 14:1994;257-263.
    • (1994) Risk Anal. , vol.14 , pp. 257-263
    • McCormick, J.J.1    Maher, V.M.2
  • 59
    • 0025134071 scopus 로고
    • Effects of hepatic peroxisome proliferators and 12-O-tetradecanoylphorbol 13-acetate on catalase and other enzyme activities of embryonic cells in vitro
    • Mikalsen S.O., Ruyter B., Sanner T. Effects of hepatic peroxisome proliferators and 12-O-tetradecanoylphorbol 13-acetate on catalase and other enzyme activities of embryonic cells in vitro. Biochem. Pharmacol. 39:1990;527-535.
    • (1990) Biochem. Pharmacol. , vol.39 , pp. 527-535
    • Mikalsen, S.O.1    Ruyter, B.2    Sanner, T.3
  • 60
    • 0029003860 scopus 로고
    • Malignant transformation of HPV-immortalized human oral keratinocytes by chemical carcinogens
    • Min B.-M., Woo K.M., Baek J.-H., Lee G., Park N.-H. Malignant transformation of HPV-immortalized human oral keratinocytes by chemical carcinogens. Int. J. Oncol. 7:1995;249-256.
    • (1995) Int. J. Oncol. , vol.7 , pp. 249-256
    • Min, B.-M.1    Woo, K.M.2    Baek, J.-H.3    Lee, G.4    Park, N.-H.5
  • 61
    • 0025006115 scopus 로고
    • Relationship between chemically induced Ha-ras mutation and transformation of BALB/c 3T3 cells: Evidence for chemical-specific activation and cell type specific recruitment of oncogene in transformation
    • Nakazawa H., Aguelon A.M., Yamasaki H. Relationship between chemically induced Ha-ras mutation and transformation of BALB/c 3T3 cells: evidence for chemical-specific activation and cell type specific recruitment of oncogene in transformation. Mol. Carcinogen. 3:1990;202-209.
    • (1990) Mol. Carcinogen , vol.3 , pp. 202-209
    • Nakazawa, H.1    Aguelon, A.M.2    Yamasaki, H.3
  • 62
    • 0026465655 scopus 로고
    • Identification and quantification of a carcinogen-induced molecular initiation event in cell transformation
    • Nakazawa H., Aguelon A.M., Yamasaki H. Identification and quantification of a carcinogen-induced molecular initiation event in cell transformation. Oncogene. 7:1992;2295-2301.
    • (1992) Oncogene , vol.7 , pp. 2295-2301
    • Nakazawa, H.1    Aguelon, A.M.2    Yamasaki, H.3
  • 63
    • 0002593311 scopus 로고
    • Extrapolation of results from animal inhalation studies with particles to humans
    • D.L. Dungworth, J.L. Muderly, & G. Oberdorster. Washington, DC: ILSI Press
    • Oberdorster G. Extrapolation of results from animal inhalation studies with particles to humans. Dungworth D.L., Muderly J.L., Oberdorster G. Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract. 1994;335-354 ILSI Press, Washington, DC.
    • (1994) Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract , pp. 335-354
    • Oberdorster, G.1
  • 64
    • 0027179604 scopus 로고
    • Identification and characterization of multiple mdm2 proteins and mdm-2-p53 protein complexes
    • Olson D.C., Marechal V., Momand J., Chen J., Romocki C., Levine A.J. Identification and characterization of multiple mdm2 proteins and mdm-2-p53 protein complexes. Oncogene. 8:1993;2353-2360.
    • (1993) Oncogene , vol.8 , pp. 2353-2360
    • Olson, D.C.1    Marechal, V.2    Momand, J.3    Chen, J.4    Romocki, C.5    Levine, A.J.6
  • 66
    • 0025013484 scopus 로고
    • Colorectal carcinogenesis: Sequential steps in the in vitro immortalization and transformation of human colonic epithelial cells
    • Paraskeva C., Corfield A.P., Harper S., Hague A., Audcent K., Williams A.C. Colorectal carcinogenesis: sequential steps in the in vitro immortalization and transformation of human colonic epithelial cells. Anticancer Res. 10:1990;1189-1200.
    • (1990) Anticancer Res. , vol.10 , pp. 1189-1200
    • Paraskeva, C.1    Corfield, A.P.2    Harper, S.3    Hague, A.4    Audcent, K.5    Williams, A.C.6
  • 67
    • 0029033493 scopus 로고
    • Cumulative gene and chromosome alterations associated with in vitro neoplastic transformation of human cervical cells
    • Popescu N.C., Zimonjic D.B., Simpson S., DiPaolo J.A. Cumulative gene and chromosome alterations associated with in vitro neoplastic transformation of human cervical cells. Int. J. Oncology. 7:1995;279-285.
    • (1995) Int. J. Oncology , vol.7 , pp. 279-285
    • Popescu, N.C.1    Zimonjic, D.B.2    Simpson, S.3    DiPaolo, J.A.4
  • 68
    • 0028295736 scopus 로고
    • Inhibition of gap junctional intercellular communication in Syrian hamster embryo cells by TPA, retinoic acid and DDT
    • Rivedal E., Yamasaki H., Sanner T. Inhibition of gap junctional intercellular communication in Syrian hamster embryo cells by TPA, retinoic acid and DDT. Carcinogenesis. 15:1994;689-694.
    • (1994) Carcinogenesis , vol.15 , pp. 689-694
    • Rivedal, E.1    Yamasaki, H.2    Sanner, T.3
  • 69
    • 0019409895 scopus 로고
    • Metal salts as promoters of in vitro morphological transformation of hamster embryo cells initiated by benzo[a]pyrene
    • Rivedal E., Sanner T. Metal salts as promoters of in vitro morphological transformation of hamster embryo cells initiated by benzo[a]pyrene . Cancer Res. 41:1981;2950-2953.
    • (1981) Cancer Res. , vol.41 , pp. 2950-2953
    • Rivedal, E.1    Sanner, T.2
  • 70
    • 0025362129 scopus 로고
    • Modification of gap junctional intracellular communication by changes in extracellular pH in Syrian hamster embryo cells
    • Ruch R.J., Klaunig J.E., Kerckaert G.A., LeBoeuf R.A. Modification of gap junctional intracellular communication by changes in extracellular pH in Syrian hamster embryo cells. Carcinogenesis. 11:1990;909-913.
    • (1990) Carcinogenesis , vol.11 , pp. 909-913
    • Ruch, R.J.1    Klaunig, J.E.2    Kerckaert, G.A.3    LeBoeuf, R.A.4
  • 71
    • 0027357967 scopus 로고
    • A critical approach to the malignant transformation of human breast epithelial cells with chemical carcinogens
    • Russo J., Calaf G., Russo I.H. A critical approach to the malignant transformation of human breast epithelial cells with chemical carcinogens. Crit. Rev. Oncogen. 4:1993;403-417.
    • (1993) Crit. Rev. Oncogen. , vol.4 , pp. 403-417
    • Russo, J.1    Calaf, G.2    Russo, I.H.3
  • 72
    • 0028294877 scopus 로고
    • Biology of disease - maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancer
    • Sell S., Pierce G.B. Biology of disease - maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancer. Lab. Invest. 70:1994;6-22.
    • (1994) Lab. Invest. , vol.70 , pp. 6-22
    • Sell, S.1    Pierce, G.B.2
  • 73
    • 0028360110 scopus 로고
    • Growth suppression of transformed BALB/c 3T3 cells by transforming growth factor beta-1 occurs only in the presence of their normal counterparts
    • Silingardi P., Klein J.L., Mesnil M., Yamasaki H. Growth suppression of transformed BALB/c 3T3 cells by transforming growth factor beta-1 occurs only in the presence of their normal counterparts. Carcinogenesis. 15:1994;1181-1185.
    • (1994) Carcinogenesis , vol.15 , pp. 1181-1185
    • Silingardi, P.1    Klein, J.L.2    Mesnil, M.3    Yamasaki, H.4
  • 75
    • 0000973407 scopus 로고
    • Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP
    • Tennant R.W., Ashby J. Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP. Mutation Res. 257:1991;229-306.
    • (1991) Mutation Res. , vol.257 , pp. 229-306
    • Tennant, R.W.1    Ashby, J.2
  • 76
    • 0028225421 scopus 로고
    • Immortalization of BALB/c mouse embryo fibroblasts alters SV40 large T-antigen interactions with the tumor suppressor p53 and results in a reduced SV40 transformation efficiency
    • Tiemann F., Deppert W. Immortalization of BALB/c mouse embryo fibroblasts alters SV40 large T-antigen interactions with the tumor suppressor p53 and results in a reduced SV40 transformation efficiency. Oncogene. 9:1994;1907-1915.
    • (1994) Oncogene , vol.9 , pp. 1907-1915
    • Tiemann, F.1    Deppert, W.2
  • 77
    • 0002024908 scopus 로고
    • Detection of non-mutagenic carcinogens using cultured Syrian hamster embryo cells
    • Tsutsui T., Barrett J.C. Detection of non-mutagenic carcinogens using cultured Syrian hamster embryo cells. Altern. Anim. Test. Exp. 1:1991;65-73.
    • (1991) Altern. Anim. Test. Exp. , vol.1 , pp. 65-73
    • Tsutsui, T.1    Barrett, J.C.2
  • 78
    • 0027276531 scopus 로고
    • Ability of peroxisome proliferators to induce cell transformation, chromosome aberrations and peroxisome proliferation in cultured Syrian hamster embryo cells
    • Tsutsui T., Watanabe E., Barrett J.C. Ability of peroxisome proliferators to induce cell transformation, chromosome aberrations and peroxisome proliferation in cultured Syrian hamster embryo cells. Carcinogenesis. 14:1993;611-618.
    • (1993) Carcinogenesis , vol.14 , pp. 611-618
    • Tsutsui, T.1    Watanabe, E.2    Barrett, J.C.3
  • 79
    • 0022706238 scopus 로고
    • Decreased numbers of spindle and cytoplasmic microtubules in hamster embryo cells treated with a carcinogen, diethylstilbestrol
    • Tucker R.W., Barrett J.C. Decreased numbers of spindle and cytoplasmic microtubules in hamster embryo cells treated with a carcinogen, diethylstilbestrol. Cancer Res. 46:1986;2088-2095.
    • (1986) Cancer Res. , vol.46 , pp. 2088-2095
    • Tucker, R.W.1    Barrett, J.C.2
  • 80
    • 0028817664 scopus 로고
    • Repression of platelet-derived growth factor beta-receptor expression by mitogenic growth factors and transforming oncogenes in murine 3T3 fibroblasts
    • Vaziri C., Faller D.V. Repression of platelet-derived growth factor beta-receptor expression by mitogenic growth factors and transforming oncogenes in murine 3T3 fibroblasts. Mol. Cell. Biol. 15:1995;1244-1253.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1244-1253
    • Vaziri, C.1    Faller, D.V.2
  • 81
    • 0023585254 scopus 로고
    • Marked synergism of dimethylnitrosamine carcinogenesis in rats exposed to cadmium
    • Wade G.G., Mandel R., Ryser H.J. Marked synergism of dimethylnitrosamine carcinogenesis in rats exposed to cadmium. Cancer Res. 47:1987;6606-6613.
    • (1987) Cancer Res. , vol.47 , pp. 6606-6613
    • Wade, G.G.1    Mandel, R.2    Ryser, H.J.3
  • 82
    • 0023940766 scopus 로고
    • Further evidence for the involvement of gap-junctional intercellular communication in induction and maintenance of transformed foci in BALB/c 3T3 cells
    • Yamasaki H., Katoh F. Further evidence for the involvement of gap-junctional intercellular communication in induction and maintenance of transformed foci in BALB/c 3T3 cells. Cancer Res. 48:1988;3490-3495.
    • (1988) Cancer Res. , vol.48 , pp. 3490-3495
    • Yamasaki, H.1    Katoh, F.2
  • 83
    • 0026604284 scopus 로고
    • Malignant transformation of human fibroblast cell strain MSU-1.1 by (+/-)-7β,8α- dihydroxy-9α,10α-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene
    • Yang D., Louden C., Reinhold D.S., Kohler S.K., Maher V.M., McCormick J.J. Malignant transformation of human fibroblast cell strain MSU-1.1 by (+/-)-7β,8α- dihydroxy-9α,10α-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene , Proc. Natl. Acad. Sci. USA. 89:1992;2237-2241.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2237-2241
    • Yang, D.1    Louden, C.2    Reinhold, D.S.3    Kohler, S.K.4    Maher, V.M.5    McCormick, J.J.6
  • 84
    • 0026703557 scopus 로고
    • Correlation between the conformational phenotype of p53 and its subcellular location
    • Zerrahn J., Deppert W., Weidemann D., Patschinsky T., Richards F., Milner J. Correlation between the conformational phenotype of p53 and its subcellular location. Oncogene. 7:1992;1371-1381.
    • (1992) Oncogene , vol.7 , pp. 1371-1381
    • Zerrahn, J.1    Deppert, W.2    Weidemann, D.3    Patschinsky, T.4    Richards, F.5    Milner, J.6


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