pH effects on the lifespan and transformation frequency of Syrian hamster embryo (SHE) cells

Carcinogenesis

Volumn 17, Issue 9, 1996, Pages 1819-1824

  Kerckaert, Gary A ^a   LeBoeuf, Robert A ^a   Isfort, Robert J ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; TUMOR PROMOTER;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL POPULATION; CELL SURVIVAL; CELL TRANSFORMATION; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; NONHUMAN; PH; PRIORITY JOURNAL; SENESCENCE; SYRIAN HAMSTER;

EID: 0029791458     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.9.1819     Document Type: Article

References (45)

1. Berwald, Y. and Sachs, L. (1965) In vitro transformation of normal cells to tumor cells by carcinogenic hydrocarbons, J. Natl Cancer Inst., 35, 641-661.
2. Barrett, J.C. and Ts'o, P.O.P. (1978) Evidence for the progressive nature of neoplastic transformation in vitro. Proc. Natl Acad. Sci. USA. 75, 3761-3765.
3. LeBoeuf, R.A. and Kerckaert, G.A. (1986) The induction of transformed-like morphology and enhanced growth in Syrian hamster embryo cells grown at acidic pH. Carcinogenesis, 7, 1431-1440.
4. LeBoeuf, R.A. and Kerckaert, G.A. (1987) Enhanced morphological transformation of early passage Syrian hamster embryo cell cultures in medium with a reduced bicarbonate concentration and pH. Carcinogenesis, 8, 689-697.
5. LeBoeuf, R.A., Kerckaert, G.A., Poiley, J.A. and Raineri, R. (1989) An interlaboratory comparison of enhanced morphological transformation of Syrian hamster embryo cells cultured under conditions of reduced bicarbonate concentration and pH. Mutation Res., 222, 205-218.
6. LeBoeuf, R.A., Kerckaert, G.A., Aardema, M.J. and Gibson, D.P. (1990) Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.70. Cancer Res., 50, 3722-3729.
7. LeBoeuf, R.A., Kerckaert, G.A., Aardema, M.J., Gibson, D.P., Brauninger, R. and Isfort, R.J. (1995) The pH 6.7 Syrian hamster embryo cell transformation assay for assessing the carcinogenic potential of chemicals. Mutat. Res., in press.
8. Isfort, R.J., Kerckaert, G.A. and LeBoeuf, R.A. (1995) Comparison of the standard and reduced pH Syrian hamster embryo (SHE) cell in vitro transformation assays abilities to predict the carcinogenic potential of chemicals. Mutat. Res., in press.
9. Isfort, R.J., Cody, D.B., Doersen, C. Kerckaert, G.A. and LeBoeuf, R.A. (1994) Alterations in cellular differentiation, mitogenesis, cytoskeleton and growth characteristics during Syrian hamster embryo cell multistep in vitro transformation. Int. J. Cancer, 59, 114-125.
10. Pienta, R.J., Poiley, J.A. and Lebhertz III, W.B. (1977) Morphological Iransformation of early passage golden Syrian hamster embryo cells derived from cryopreserved cultures as a reliable in vitro bioassay for identifying diverse carcinogens. Int. J. Cancer, 19, 642-655.
11. DiPaolo, J.A. (1980) Quantitative in vitro transformation of golden Syrian hamster embryo cells with the use of frozen stored cells. J. Natl Cancer Inst., 64, 1485-1489.
12. Inuoe, K., Sunawaka, T. and Takayama, S. (1980) Studies of in vitro cell transformation and mutagenicity by surfactants and other compounds. Food Cosmet. Toxicol. 18, 289-296.
13. Kerckaert, G.A., Isfort, R.J., Carr, G.J., Aardema, M.J. and LeBoeuf, R.A. (1995) A comprehensive protocol for conducting the Syrian hamster embryo cell transformation assay at pH 6.70. Mutation Res., in press.
14. Schuman, R.K., Pienta, R.J., Poiley, J.A. and Lebhertz III, W.B. (1979) Effect of fetal bovine serum on 3-methylcholanthrene-induced transformation of hamster cells in vitro. In Vitro, 15, 7330-735.
15. Tu, A., Hallowell, S., Sivak, A. et al. (1986) An interlaboratory comparison of transformation in Syrian hamster embryo cells with model and coded compounds. Environ. Mutagen., 8, 77-98.
16. Barrett, J.C. and Lamb, P.W. (1985) Tests with the Syrian hamster embryo cell transformation assay. In Ashby, J., deSerres, F.J., Draper, M., Ishidate, M., Margolin, B.H. and Shelby, M.D. (eds), Progress in mutation research-evaluation of short term tests for carcinogens. Elsevier Science, NY, pp. 623-628.
17. Jones, C., Huberman, E., Callahan, M.F. et at. (1988) An interlaboratory evaluation of the Syrian hamster embryo cell transformation assay using eighteen coded chemicals. Toxicol. In Vitro, 2, 103-116.
18. LeBoeuf, R.A., Lin, P., Kerckaert, G.A. and Gruenstein, E. (1992) Intracellular acidification is associated with enhanced morphological transformation in Syrian hamster embryo cells. Cancer Res., 52, 144-148.
19. Isfort, R.J., Cody, D.B., Asquith, T.N., Ridder, G.M., Stuard, S.B. and LeBoeuf, R.A. (1993) Induction of protein phosphorylation, protein synthesis, immediate-early-gene expression and cellular proliferation by intracellular pH modulation. Eur. J. Biochem., 213, 349-357.
20. Isfort, R.J., Cody, D.B., Asquith, T.N. and LeBoeuf, R.A. (1992) Phenotypic differences between Syrian hamster embryo cells cultured at pH 6.7 or 7.3. In Vitro Cell. Dei: Biol., 28A, 635-642.
21. Hayflick, L. (1976) The cell biology of human aging. N. Engl. J. Med., 295, 1302-1308.
22. Greider, C.W. (1994) Mammalian telomere dynamics: healing, fragmentation, shortening and stabilization. Curr. Opinions. Genetic. Dev., 4, 203-211.
23. Bols, B.L.M.C., Gillis, K.C.P.M. Naaktgeboren, J.M., Lohman, P.H.M., Niericker, M. and Simons, J.W.I.M. (1993) Immortalization of Syrian hamster embryo cells: probabilistic event or deterministic process. Cancer Res., 53, 4797-4802.
24. Sasaki, M., Honda, T., Yamada, H., Wake, N., Barrett, J.C. and Oshimura, M. (1994) Evidence for multiple pathways to cellular senescence. Cancer Res., 54, 6090-6093.
25. Laderoute, M.P. (1994) A new perspective on the nature of the cancer problem: anti-cellular senescence. Mol. Carcinogen., 10, 125-133.
26. Bols, B.L.M.C., Naaktgeboren, J.M. and Simons, J.W.I.M. (1991) Immortalization of Syrian hamster embryo cells is in itself a multistep event. Cancer Res., 51, 1177-1184.
27. Bols, B.L.M.C., Naaktgeboren, J.M., Lohman, P.H.M. and Simons, J.W.I.M. (1992) Immortalization of carcinogen-treated Syrian hamster embryo cells occurs indirectly via an induced process. Cancer Res., 52, 2253-2256.
28. Isfort, R.J., Kerckaert, G.A., Cody, D.B., Carter, J., Driscoll, K.E. and LeBoeuf, R.A. (1996) Isolation and biological characterization of morphological transformation sensitive Syrian hamster embryo cells. Carcinogenesis, 17, 997-1005.
29. Armitage, P. (1971) Statistical methods in medical research. Blackwell Scientific Publications, Oxford, pp. 135-138.
30. Ueo, H., Nakano, S., Ts'o, P.O.P. and Bruce, S. (1990) Tumor promoters retard the loss of a transient subpopulation of cells in low passage Syrian hamster cell cultures. J. Cell Physiol., 142, 505-513.
31. Koi, M., Afshari, C.A., Annab, L.A. and Barrett, J.C. (1989) Role of a tumor-suppressor gene in the negative control of anchorage-independent growth of Syrian hamster cells. Proc. Natl Acad. Sci. USA, 86, 8773-8777.
32. Sugawara, O., Oshimura, M., Koi, M., Annab, L.A. and Barrett, J.C. (1990) Induction of cellular senescence in immortalized cells by human chromosome I. Science, 247, 707-710.
33. Wadhwa, R., Pereira-Smith, O.M., Reddel, R.R., Sugimoto, Y., Mitsui, Y. and Kaul, S.C. (1995) Correlation between complementation group for immortality and the cellular distribution of mortalin. Exp. Cell Res., 216, 101-106.
34. Liu, X.T., Stewart, C.A., King, R.L., Danner, D.A., Dell'Orco, R.T. and McClung, J.K. (1994) Prohibitin expression during cellular senescence of human diploid fibroblasts. Biochem. Biophys. Res. Commun., 201, 409-414.
35. Tollefsbol, T.O. and Andrews, L.G. (1993) Mechanisms for methylation-mediated gene silencing and aging. Med. Hypotheses, 41, 83-92.
36. Nakanishi, M., Robetorye, R.S., Adami, G.R., Pereira-Smith, O.M. and Smith, J.R. (1995) Identification of the active region of the DNA synthesis inhibitory gene 21Sdi1/CIP1/WAF1. EMBO J., 14, 555-563.
37. Venable, M.E., Blobe, G.C. and Obeid, L.M. (1994) Identification of a defect in the phospholipase D/diacylglycerol pathway in cellular senescence. J. Biol. Chem., 269, 26040-26044.
38. Affarwal, B.B., Totpal, K., LaPushin, R., Chaturvedi, M.M., Pereira-Smith, O.M. and Smith, J.R. (1995) Diminished responsiveness of senescent normal human fibroblasts to TNF-dependent proliferation and interleukin production is not due to its effect on the receptors or on the activation of a nuclear factor NF-kappa B. Exp. Cell Res., 218, 381-388.
39. Isfort, R.J., Stuard, S.B., Cody, D.B., Ridder, G.M. and LeBoeuf, R.A. (1995) Modulation of the mitogen induced calcium signal by extracellular/intracellular pH in Syrian hamster embryo (SHE) cells - implications for the role of calcium in mitogenic signalling. Eur. J. Biochem., 234, 801-810.
40. Isfort, R.J., Cody, D.B., Stuard, S.B., Ridder, G.M. and LeBoeuf, R.A. (1995) Calcium functions as a transcriptional and mitogenic repressor in Syrian hamster embryo cells: roles of pH and calcium in controlling embryonic cell differentiation and proliferation. Exp. Cell Res., in press.
41. Nakano, S. and Ts'o, P.O.P. (1981) Cellular differentiation and neoplasia: characterization of subpopulations of cells that have neoplasia-related growth properties in Syrian hamster embryo cell cultures. Proc. Natl Acad. Sci. USA, 78, 4995-4999.
42. Isfort, R.J., Cody, D.B., Kerckaert, G.A., Stuard, S.B., Tycko, B., Ridder, G.M. and LeBoeuf, R.A. (1995) Morphological transformation in Syrian hamster embryo (SHE) cells results from a block in cellular differentiation mediated by the tumor suppressor gene H19. Proc. Natl Acad. Sci. USA, in press.
43. Sell, S. and Pierce, G.B. (1994) Biology of disease - maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancer. Lab. Invest., 70, 6-22.
44. Williams, R.L., Hilton, D.J., Pease, S. et al. (1988) Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature, 336, 684-687.
45. Piquet-Pellorce, C., Grey, L., Mereau, A. and Heath, J.K. (1994) Are LIF and related cytokines functionally equivalent? Exp. Cell Res., 213, 340-347.