Isolation and biological characterization of morphological transformation-sensitive Syrian hamster embryo cells

Carcinogenesis

Volumn 17, Issue 5, 1996, Pages 997-1005

  Isfort, Robert J ^a   Kerckaert, Gary A ^a   Cody, David B ^a   Carter, Janet ^a   Driscoll, Kevin E ^a   LeBoeuf, Robert A ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN; GROWTH FACTOR; STEM CELL FACTOR; VIMENTIN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL SUBPOPULATION; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO CELL; EPITHELIUM CELL; MESENCHYME; NONHUMAN; PRIORITY JOURNAL; STEM CELL; SYRIAN HAMSTER;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CRICETINAE; EMBRYO; FEMALE; GROWTH SUBSTANCES; KERATINS; MESOCRICETUS; PREGNANCY; VIMENTIN;

EID: 0029951999     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.5.997     Document Type: Article

References (46)

1. Sell,S. and Pierce,G.B. (1994) Biology of disease - maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancer. Lab. Invest., 70, 6-22.
2. Sumi,T., Nishina,Y., Kosaka,M., Sukuda,M., and Nishimune,Y. (1993) Suppression of tumorigenicity in temperature-sensitive mutants of embryonal carcinoma cells by induction of cell differentiation at nonpermissive temperature. Int. J. Cancer. 54, 333-337.
3. Park,S., Bemard,A., Bove,K.E., Sens,D.A., Hazen-Martin,D.J., Garvin,A.J. and Haber,D.A. (1993) Inactivation of WT1 in nephrogenic rest, genetic precursors to Wilms tumor. Nature Gener., 5, 363-367.
4. Bisgaard,H.C., Ton,P.T., Nagy,P. and Thorgeirsson,S.S. (1994) Phenotypic modulation of keratins, vimentin, and alpha-fetoprotein in cultured rat liver epithelial cells after chemical, oncogene, and spontaneous transformation. J. Cell. Physiol., 159, 485-494.
5. Sun,G.X., Wormsley,S., Sparkes,R.S., Naeim,F. and Gale,R.P. (1991) Where does transformation occur in acute leukemia? Leukemia Res., 15, 1183-1189.
6. Williams,E.D., Lowes,A.P., Williams,D. and Williams,G.T. (1992) A stem cell niche theory of intestinal crypt maintenance based on a study of somatic mutation in colonic mucosa. Am. J. Pathol., 141, 773-776.
7. Rubin,H. (1993) Spontaneous transformation as aberrant epigenesis. Differentiation. 53, 123-137.
8. Isfort,R.J., Cody,D.B., Kerckaert,G.A., Stuart,S.B., Tycko,B., Ridder,G.M. and LeBoeuf,R.A. (1996) Morphological transformation in Syrian hamster embryo (SHE) cells results from a block in cellular differentiation mediated by the tumor suppressor gene H19. Proc. Natl Acad. Sci. USA, submitted for publication.
9. Nakano,S. and Ts'o,P.O.P. (1981) Cellular differentiation and neoplasia: characterization of subpopulations of cells that have neoplasia-related growth properties in Syrian hamster embryo cell cultures. Proc. Natl Acad. Sci. USĀ, 78, 4995-4999.
10. Nakano,S., Ueo,H., Bruce,S.A. and Ts'o,P.O.P. (1985) A contact-insensitive subpopulation in Syrian hamster cell cultures with a greater susceptibility to chemically induced neoplastic transformation. Proc. Natl Acad. Sci. USA. 82, 5005-5009.
11. Nakano,S., Bruce,S.A., Ueo,H. and Ts'o,P.O.P. (1982) A qualitative and quantitative assay for cells lacking postconfluence inhibition of cell division: characterization of this phenotype in carcinogen-treated Syrian hamster embryo cells in culture. Cancer Res., 42, 3132-3137.
12. Isfort,R.J., Cody,D.B., Doersen,C.J., Kerckaert,G.A. and LeBoeuf,R.A. (1994) Alterations in cellular differentiation, mitogenesis. cytoskeleton and growth characteristics during Syrian hamster embryo cell multistep in vitro transformation. Int. J. Cancer, 59, 114-125.
13. Bols,B.L.M.C., Naaktgeboren,J.M. and Simons,J.W.I.M. (1991) Immortalization of Syrian hamster embryo cells is in itself a multistep event. Cancer Res., 51, 1177-1184.
14. Bols,B.L.M.C., Naaktgeboren,J.M., Lohman,P.H.M. and Simons,J.W.I.M. (1992) Immortalization of carcinogen-treated Syrian hamster embryo cells occurs indirectly via an induced process. Cancer Res., 52, 2253-2256.
15. Isfort,R.J., Kerckaert,G.A. and LeBoeuf,R.A. (1996) Comparison of the standard and reduced pH Syrian hamster embryo (SHE) cell in vitro transformation assays to predict the carcinogenic potential of chemicals. Mutat. Res., in press.
16. LeBoeuf,R.A., Kerckaert,G.A., Aardema,M.J., Gibson,D.P., Brauninger,R. and Isfort,R.J. (1996) The pH 6.7 Syrian hamster embryo cell transformation assay for assessing the carcinogenic potential of chemicals. Mutat. Res., in press.
17. Watanabe,M. and Suzuki,K. (1991) Expression dynamics of transforming phenotypes in X-irradiated Syrian golden hamster embryo cells. Mutat. Res., 249, 71-80.
18. LeBoeuf,R.A. and Kerckaert,G.A. (1987) Enhanced morphological transformation of early passage Syrian hamster embryo cells cultured in medium with a reduced bicarbonate concentration and pH. Carcinogenesis. 8, 689-697.
19. LeBoeuf,R.A., Kerckaert,G.A., Aardema,M.J. and Gibson,D.P. (1990) Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.7. Cancer Res.. 50, 3722-3729.
20. Isfort,R.J., Cody,D.B., Asquith,T.N., Ridder,G.M., Stuard,S.B. and LeBoeuf,R.A. (1993) Induction of protein phosphorylation. protein synthesis, immediate early gene expression and cellular proliferation by intracellular pH modulation. Eur. J. Biochem., 213, 349-357.
21. Isfort,R.J., Cody,D.B., Asquith,T.N. and LeBoeuf,R.A. (1992) Phenotype differences between Syrian hamster embryo cells cultured at pH 6.7 or pH 7.3. In Vitro Cell Dev. Biol., 28A, 635-642.
22. Isfort,R.J., Cody,D.B., Kerckaert,G.A. and LeBoeuf,R.A. (1994) Growth factor responsiveness and alterations in growth factor homeostasis in Syrian hamster embryo cells during in vitro transformation. Carcinogenesis. 15, 1203-1209.
23. Sun,T.T., Tseng,S.C.G., Huang,A.J.W., Cooper,D., Schermer,A., Lynch,M.H., Weiss,R. and Eichner,R. (1985) Monoclonal antibody studies of mammalian epithelial keratins: a review. Ann. NY Acad. Sci., 455, 307-329.
24. Ben-Ze'ev,A. (1984) Differential control of cytokeratins and vimentin synthesis by cell-cell contact and cells spreadins in cultured epithelial cells. J. Cell Biol., 99, 1424-1433.
25. Ben-Ze'ev,A. (1985) Cell density and cell shape-related regulation of vimentin and cytokeratin synthesis. Exp. Cell Res., 157, 520-532.
26. Pagan,R., Llobera,M and Vilaro,S. (1995) Epithelial-mesenchymal transition in cultured neonatal hepatocytes. Hepatology, 21, 820-831.
27. Ben-Ze'ev,A. (1990) Application of two-dimensional gel electrophoresis in the study of cytoskeletal protein regulation during growth activation and differentiation. Electrophoresis, 11, 191-200.
28. Ben-Ze'ev,A. (1987) The changes in cell shape and contacts in the regulation of cytoskeleteon expression during differentiation. J. Cell Sci., 8 (Suppl.), 293-312.
29. Engers,R., Gerharz,C.D., Moll,R., Pohl,A., Sarbia,M. and Gabbert,H.E. (1994) Interclonal heterogeneity in a human epitheloid-sarcoma cell line (GRU-1). Int. J. Cancer, 59, 548-553.
30. Moses,H.L., Yang,E.Y. and Pietenpol,J.A. (1990) TGFβ1 stimulation and inhibition of cell proliferation: new mechanistic insights. Cell, 63, 245-247.
31. Sporn,M.B. and Roberts,A.B. (1990) TGFβ: problems and prospects. Cell Regul., 1, 875-882.
32. Massague J. (1990) The transforming growth factor-β family. Annu. Rev. Cell Biol., 6, 597-641.
33. Verdi,J.M., Ip,M., Yancopoulos,G.D. and Anderson,D.J. (1994) Expression of trk in MAH cell lacking the p75 low-affinity nerve growth factor receptor is sufficient to permit nerve growth factor-induced differentiation to postmitotic neurons. Proc. Natl Acad. Sci. USA, 91, 3949-3953.
34. Di-Marco,E., Mathor,M., Bondanza,S., Cutuli,N., Marchisio,P.C., Cancedda,R. and De-Lucca,M. (1993) Nerve growth factor binds to normal human keratinocytes through high and low affinity receptors and stimulates their growth by a novel autocrine loop. J. Biol. Chem., 268, 22838-22846.
35. Tischler,A.S., Riseberg,J.C., Hardenbrook,M.A. and Cherington,V. (1993) Nerve growth factor is a potent inducer of proliferation and neuronal differentiation for adult rat chromaffin cells in vitro. J. Neurosci., 13, 1533-1542.
36. Chevalier,S., Praloran,V., Smith,C., MacGrogan,D., Ip,N.Y., Yancopoulos,G.D., Brachet,P., Pouplard,A. and Gascan,H. (1994) Expression and functionality of the trk A proto-oncogene product/NGF receptor in undifferentiated hematopoietic cells. Blood, 83, 1479-1485.
37. Gearing,D.P. et al. (1992) The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor. Science, 255, 1434-1437.
38. Grove,R.I., Eberhardt,C. Abid,S., Mazzucco,C., Liu,J., Kiener,P., Todaro,G. and Shoyab,M. (1993) Oncostatin M is a mitogen for rabbit vascular smooth muscle cells. Proc. Natl Acad. Sci. USA, 90, 823-827.
39. Rose,T.M., Weiford,D.M., Gunderson,N.L. and Bruce,A.G. (1994) Oncostatin M (OSM) inhibits the differentiation of pluripotent embryonic stem cells in vitro. Cytokine, 6, 48-54.
40. Bruce,A.G., Linsley,P.S. and Rose,T.M. (1992) Oncostatin M. Prog. Growth Factor Res., 4, 157-170.
41. Tajima,H., Matsumoto,K. and Nakamura,T. (1991) Hepatocyte growth factor has potent anti-proliferative activity in various tumor cell lines. FEBS Lett., 291, 229-232.
42. Rubin,J.S., Bottaro,D.P. and Aaronson,S.A. (1993) Hepatocyte growth factor/scatter factor and its receptor, the c-met protooncogene product, Biochim. Biophys. Acta. 1155, 357-371.
43. Wrana,J.L. (1994) H19, a tumor suppressing RNA? BioEssays, 16, 89-90.
44. Poirier,F., Chan,C.T.J., Timmons,P.M., Robertson,E.J., Evans,M.J. and Rigby,P.W.J. (1991) The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo. Development, 113, 1105-1114.
45. Pachnis,V., Brannan,C.I. and Tilghman,S.M. (1988) The structure and expression of a novel gene activated in early mouse embryogenesis. EMBO J.. 7, 673-681.
46. Rachmilewitz,J., Gileadi,O., Elda-Geva,T., Schneider,T., de-Groot,N. and Hochberg,A. (1992) Transcription of the H19 gene in differentiating cytotrophoblasts from human placenta. Mol. Reprod. Dev., 32, 196-202.