Conjugation of glutathione with a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, catalyzed by rat hepatic glutathione-S-transferases

Drug Metabolism and Disposition

Volumn 24, Issue 4, 1996, Pages 436-446

  Tang, Wei ^a   Borel, Anthony G ^a   Abbott, Frank S ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; GLUTATHIONE TRANSFERASE; VALPROIC ACID;

ARTICLE; BIOTRANSFORMATION; CATALYSIS; DRUG CONJUGATION; DRUG METABOLISM; ENZYME ACTIVITY; LIVER MICROSOME; LIVER TOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN MODIFICATION; TANDEM MASS SPECTROMETRY;

ANIMALS; BILE; CHROMATOGRAPHY, LIQUID; FATTY ACIDS, UNSATURATED; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; RATS; RATS, SPRAGUE-DAWLEY; SUBCELLULAR FRACTIONS; VALPROIC ACID;

EID: 0029922411     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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