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Volumn 12, Issue 10, 1996, Pages 859-865

Conference summary: Novel HIV therapies - From discovery to clinical proof of concept

Author keywords

[No Author keywords available]

Indexed keywords

ACYCLIC NUCLEOSIDE; ADEFOVIR; CAPSID PROTEIN; CD4 ANTIGEN; DIDANOSINE; GAG PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; INTEGRASE; INTERLEUKIN 2; NEF PROTEIN; NEVIRAPINE; NUCLEIC ACID; PIPERAZINE DERIVATIVE; PROTEINASE; REGULATOR PROTEIN; REV PROTEIN; RIBONUCLEASE H; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIF PROTEIN; VIRUS ENVELOPE PROTEIN; VPR PROTEIN; VPU PROTEIN; ZALCITABINE; ZIDOVUDINE;

EID: 0029957764     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.1996.12.859     Document Type: Conference Paper
Times cited : (5)

References (32)
  • 2
    • 0028811974 scopus 로고
    • Viral dynamics in human immunodeficiency virus type 1 infection
    • Wei X, Ghosh SK, Taylor ME, et al.: Viral dynamics in human immunodeficiency virus type 1 infection. Nature (London) 1995:373;117-122.
    • (1995) Nature (London) , vol.373 , pp. 117-122
    • Wei, X.1    Ghosh, S.K.2    Taylor, M.E.3
  • 3
    • 0028825476 scopus 로고
    • Follicular dendritic cells and human immunodeficiency virus infectivity
    • Heath SL, Tew JG, Tew JG, Szakal AK, and Burton GO: Follicular dendritic cells and human immunodeficiency virus infectivity. Nature (London) 1995;377:740-744.
    • (1995) Nature (London) , vol.377 , pp. 740-744
    • Heath, S.L.1    Tew, J.G.2    Tew, J.G.3    Szakal, A.K.4    Burton, G.O.5
  • 4
    • 0029091047 scopus 로고
    • + T cells are infectible by human immunodeficiency virus but do not release virus after activation
    • + T cells are infectible by human immunodeficiency virus but do not release virus after activation. J Virol 1995;69:5659-5665.
    • (1995) J Virol , vol.69 , pp. 5659-5665
    • Tang, S.1    Patterson, B.2    Levy, J.A.3
  • 5
    • 0025238945 scopus 로고
    • HIV-1 replication is controlled at the level of T cell activation and proviral integration
    • Stevenson M, Stanwick TL, Dempsey MP, et al.: HIV-1 replication is controlled at the level of T cell activation and proviral integration. EMBO J 1990;9:1551-1560.
    • (1990) EMBO J , vol.9 , pp. 1551-1560
    • Stevenson, M.1    Stanwick, T.L.2    Dempsey, M.P.3
  • 6
    • 0025342694 scopus 로고
    • HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure
    • Zack JA, Arrigo SJ, Weitsman SR, et al.: HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure. Cell 1990;61:213-222.
    • (1990) Cell , vol.61 , pp. 213-222
    • Zack, J.A.1    Arrigo, S.J.2    Weitsman, S.R.3
  • 7
    • 0028912032 scopus 로고
    • Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study
    • Kovacs JA, Baseler M, Dewar RJ, et al.: Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study. N Engl J Med 1995;332:567-575.
    • (1995) N Engl J Med , vol.332 , pp. 567-575
    • Kovacs, J.A.1    Baseler, M.2    Dewar, R.J.3
  • 8
    • 13344293705 scopus 로고    scopus 로고
    • Identification of levels of maternal HIV-1 RNA associated with risk of perinatal transmission: Effect of maternal zidovudine treatment on viral load
    • Dickover RE, Garratty EM, Herman SA, et al.: Identification of levels of maternal HIV-1 RNA associated with risk of perinatal transmission: Effect of maternal zidovudine treatment on viral load. JAMA 1996;275:599-605.
    • (1996) JAMA , vol.275 , pp. 599-605
    • Dickover, R.E.1    Garratty, E.M.2    Herman, S.A.3
  • 9
    • 0028003766 scopus 로고
    • Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment
    • Connor EM, Sperling RS, Gelber R, et al.: Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N Engl J Med 1994;331:1173-1180.
    • (1994) N Engl J Med , vol.331 , pp. 1173-1180
    • Connor, E.M.1    Sperling, R.S.2    Gelber, R.3
  • 11
    • 0028791836 scopus 로고
    • Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine
    • Tsai C-C, Follis KE, Sabo A, et al.: Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine. Science 1995;270:1197-1199.
    • (1995) Science , vol.270 , pp. 1197-1199
    • Tsai, C.-C.1    Follis, K.E.2    Sabo, A.3
  • 12
    • 0028875771 scopus 로고
    • Inhibitors of HIV nucleocapsid protein zinc fingers as candidates for the treatment of AIDS
    • Rice WG, Supko JG, Malspeis L, et al.: Inhibitors of HIV nucleocapsid protein zinc fingers as candidates for the treatment of AIDS. Science 1995;270:1194-1197.
    • (1995) Science , vol.270 , pp. 1194-1197
    • Rice, W.G.1    Supko, J.G.2    Malspeis, L.3
  • 13
    • 0029328562 scopus 로고
    • HIV accessory proteins: Emerging therapeutic targets
    • Miller RH and Sarver N: HIV accessory proteins: Emerging therapeutic targets. Mol Med 1995;1:479-485.
    • (1995) Mol Med , vol.1 , pp. 479-485
    • Miller, R.H.1    Sarver, N.2
  • 14
    • 0030069139 scopus 로고    scopus 로고
    • The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains
    • Schubert U, Bour S, Ferrer-Montiel AV, et al.: The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains. J Virol 1996;70:809-819.
    • (1996) J Virol , vol.70 , pp. 809-819
    • Schubert, U.1    Bour, S.2    Ferrer-Montiel, A.V.3
  • 15
    • 0029171804 scopus 로고
    • Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention
    • Dubrovsky L, Ulrich P, Nuovo GJ, Manogue KR, Cerami A, and Bukrinsky M: Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention. Mol Med 1995;1:217-230.
    • (1995) Mol Med , vol.1 , pp. 217-230
    • Dubrovsky, L.1    Ulrich, P.2    Nuovo, G.J.3    Manogue, K.R.4    Cerami, A.5    Bukrinsky, M.6
  • 16
    • 13344261952 scopus 로고    scopus 로고
    • T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients
    • Riddell SR, Elliott M, Lewinsohn DA, et al.: T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients. Nature Med 1996;2:216-223.
    • (1996) Nature Med , vol.2 , pp. 216-223
    • Riddell, S.R.1    Elliott, M.2    Lewinsohn, D.A.3
  • 17
    • 0029060189 scopus 로고
    • Ex vivo expansion of CD4 lymphocytes from human immunodeficiency virus type 1-infected persons in the presence of combination antiretroviral agents
    • Wilson CC, Wong JT, Girard DD, et al.: Ex vivo expansion of CD4 lymphocytes from human immunodeficiency virus type 1-infected persons in the presence of combination antiretroviral agents. J Infect Dis 1995;172:88-96.
    • (1995) J Infect Dis , vol.172 , pp. 88-96
    • Wilson, C.C.1    Wong, J.T.2    Girard, D.D.3
  • 18
  • 19
    • 0027997098 scopus 로고
    • Specific tolerance across a discordant xenogeneic transplantation barrier
    • Lee LA, Gritsch HA, Sergid JJ, et al.: Specific tolerance across a discordant xenogeneic transplantation barrier. Proc Natl Acad Sci USA 1994;91:10864-10867.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10864-10867
    • Lee, L.A.1    Gritsch, H.A.2    Sergid, J.J.3
  • 20
    • 0030038944 scopus 로고    scopus 로고
    • A phase I/II pilot study of the safety of the adoptive transfer of syngeneic gene-modified cytotoxic T lymphocytes in HIV-infected identical twins
    • Walker RE, Blaese RM, Davey RT, et al.: A phase I/II pilot study of the safety of the adoptive transfer of syngeneic gene-modified cytotoxic T lymphocytes in HIV-infected identical twins. Hum Gene Ther 1996;7:367-400.
    • (1996) Hum Gene Ther , vol.7 , pp. 367-400
    • Walker, R.E.1    Blaese, R.M.2    Davey, R.T.3
  • 21
    • 0028102988 scopus 로고
    • Inhibition of human immunodeficiency virus type 1 in human T cells by a potent Rev response element decoy consisting of the 13-nucleotide minimal Rev-binding domain
    • Lee S-W, Gallardo HF, Gilboa E, and Smith C: Inhibition of human immunodeficiency virus type 1 in human T cells by a potent Rev response element decoy consisting of the 13-nucleotide minimal Rev-binding domain. J Virol 1994;68:8254-8264.
    • (1994) J Virol , vol.68 , pp. 8254-8264
    • Lee, S.-W.1    Gallardo, H.F.2    Gilboa, E.3    Smith, C.4
  • 22
    • 0025363891 scopus 로고
    • Ribozymes as potential anti-HIV-1 therapeutic agents
    • Sarver N, Cantin EM, Chang PS, et al.: Ribozymes as potential anti-HIV-1 therapeutic agents. Science 1990;247:1222.
    • (1990) Science , vol.247 , pp. 1222
    • Sarver, N.1    Cantin, E.M.2    Chang, P.S.3
  • 23
    • 0028852546 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of a second functional hairpin ribozyme against HIV-1
    • Yu M, Poeschla E, Yamada P, et al.: In vitro and in vivo characterization of a second functional hairpin ribozyme against HIV-1. Virology 1996;206:381-386.
    • (1996) Virology , vol.206 , pp. 381-386
    • Yu, M.1    Poeschla, E.2    Yamada, P.3
  • 24
    • 0027973382 scopus 로고
    • Inhibition of HIV-1 in human T-lymphocytes by retrovirally transduced anti-tat and rev hammerhead ribozymes
    • Zhou C, Bahner IC, Larson G, et al.: Inhibition of HIV-1 in human T-lymphocytes by retrovirally transduced anti-tat and rev hammerhead ribozymes. Gene 1994;149:33-39.
    • (1994) Gene , vol.149 , pp. 33-39
    • Zhou, C.1    Bahner, I.C.2    Larson, G.3
  • 25
    • 0028148012 scopus 로고
    • A molecular genetic intervention for AIDS - Effects of a transdominant negative form of Rev
    • Nabel GJ, Fox BA, Post L, et al.: A molecular genetic intervention for AIDS - effects of a transdominant negative form of Rev. Hum Gene Ther 1994;5:79-92.
    • (1994) Hum Gene Ther , vol.5 , pp. 79-92
    • Nabel, G.J.1    Fox, B.A.2    Post, L.3
  • 26
    • 0030008254 scopus 로고    scopus 로고
    • Expression of a protective gene prolongs survival of T cells in HIV-infected patients
    • in press
    • Woffendin C, Ranga U, Yang Z-Y, et al.: Expression of a protective gene prolongs survival of T cells in HIV-infected patients. Proc Natl Acad Sci USA 1996 (in press).
    • (1996) Proc Natl Acad Sci USA
    • Woffendin, C.1    Ranga, U.2    Yang, Z.-Y.3
  • 27
    • 0025231388 scopus 로고
    • Direct gene transfer into mouse muscle in vivo
    • Wolff JA, Malone RW, Williams P, et al.: Direct gene transfer into mouse muscle in vivo. Science 1990;247:1465-1468.
    • (1990) Science , vol.247 , pp. 1465-1468
    • Wolff, J.A.1    Malone, R.W.2    Williams, P.3
  • 28
    • 0027284896 scopus 로고
    • Gene inoculation generates immune response against human immunodeficiency virus type 1
    • Wang B, Ugen KE, Srikantan V, et al.: Gene inoculation generates immune response against human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1993;90:4155-4160.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4155-4160
    • Wang, B.1    Ugen, K.E.2    Srikantan, V.3
  • 29
    • 0028338654 scopus 로고
    • Direct injection of a recombinant retroviral vector induces human immunodeficiency virus-specific immune responses in mice and nonhuman primates
    • Irwin MJ, Laube LS, Lee V, et al.: Direct injection of a recombinant retroviral vector induces human immunodeficiency virus-specific immune responses in mice and nonhuman primates. J Virol 1994;68:5036-5044.
    • (1994) J Virol , vol.68 , pp. 5036-5044
    • Irwin, M.J.1    Laube, L.S.2    Lee, V.3
  • 30
    • 0029131261 scopus 로고
    • Induction of humoral and cellular immune responses to the human immunodeficiency type 1 virus in nonhuman primates by in vivo DNA inoculation
    • Wang B, Boyer J, Srikantan V, et al.: Induction of humoral and cellular immune responses to the human immunodeficiency type 1 virus in nonhuman primates by in vivo DNA inoculation. Virology 1995;211:102-112.
    • (1995) Virology , vol.211 , pp. 102-112
    • Wang, B.1    Boyer, J.2    Srikantan, V.3
  • 32
    • 34447491986 scopus 로고
    • Direct administration of retroviral vectors as therapy for HIV-1 infection
    • Abstract 406
    • Jolly DJ, Merritt J, Kowal K, et al.: Direct administration of retroviral vectors as therapy for HIV-1 infection. AIDS Res Hum Retroviruses 1995;11(Suppl 1):8166. [Abstract 406]
    • (1995) AIDS Res Hum Retroviruses , vol.11 , Issue.1 SUPPL. , pp. 8166
    • Jolly, D.J.1    Merritt, J.2    Kowal, K.3


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