Loss of primitive hematopoietic progenitors in patients with human immunodeficiency virus infection

Blood

Volumn 88, Issue 12, 1996, Pages 4568-4578

  Marandin, Aliette ^b   Katz, André ^b   Oksenhendler, Eric ^b   Tulliez, Micheline ^b   Picard, Françoise ^b   Vainchenker, William ^b   Louache, Fawzia ^a  

^a INSERM   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CELL COUNT; CELL SELECTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPHENOTYPING; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ASSAY;

EID: 0029912733     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.12.4568.bloodjournal88124568     Document Type: Article

References (45)

1. Folks TM: Human immunodeficiency virus in bone marrow: Still more questions than answers. Blood 77:1625, 1991
2. Ganser A: Abnormalities of hematopoiesis in acquired immunodeficiency syndrome. Blut 56:49, 1988
3. Scadden DT, Zon LI, Groopman JE: Pathophysiology and management of HIV-associated hematologic disorders. Blood 74:1455, 1989
4. Folks TM, Kessler SW, Orenstein JM, Justment JS, Jaffe ES, Fauci AS: Infection and replication of HIV-1 in purified progenitor cells of normal human bone marrow. Science 242:919, 1988
5. Kitano K, Abboud CN, Ryan DH, Quan SG, Baldwin GC, Golde DW: Macrophage-active colony-stimulating factors enhance human immunodeficiency virus type 1 infection in bone marrow stem cells. Blood 77:1699, 1991
6. Steinberg HN, Crumpacker CS, Chatis PA: In vitro suppression of normal human bone marrow progenitor cells by human immunodeficiency virus. J Virol 65:1765, 1991
7. Donahue RE, Johnson MM, Zon LI, Clark SC, Groopman JE: Suppression of in vitro haematopoiesis following human immunodeficiency virus infection. Nature 326:200, 1987
8. Davis BR, Schwartz DH, Marx JC, Johnson C, Berry JM, Lyding J, Merigan TC, Zander A: Absent or rare human immunodeficiency virus infection of bone marrow stem/progenitor cells in vivo. J Virol 65:1985, 1991
9. + hematopoietic progenitor cells are not a major reservoir of the human immunodeficiency virus. Blood 76:1281, 1990
10. Molina J, Scadden D, Sakaguchi M, Fuller B, Woon A, Groopman J: Lack of evidence for infection of or effect on growth of hematopoietic progenitor cells after in vivo or in vitro exposure to human immunodeficiency virus. Blood 76:2476, 1990
11. Bagnara GP, Zauli G, Giovannini M, Re MC, Furlini G, La Placa M: Early loss of circulating hemopoietic progenitors in HIV-1-infected subjects. Exp Hematol 18:426, 1990
12. Louache F, Henri A, Bettaieb A, Oksenhendler E, Raguin G, Tulliez M, Vainchenker W: Role of human immunodeficiency virus replication in defective in vitro growth of hematopoietic progenitors. Blood 80:2991, 1992
13. Stella CC, Ganser A, Hoelzer D: Defective in vitro growth of the hemopoietic progenitor cells in the acquired immunodeficiency syndrome. J Clin Invest 80:286, 1987
14. + progenitor cells from asymptomatic patients are not a major reservoir for human immunodeficiency virus-1. Blood 86:1746, 1995
15. Geissler RG, Ottmann OG, Kleiner K, Mentzel U, Bickelhaupt A, Hoelzer D, Ganser A: Decreased hematopoietic colony growth in long-term bone marrow cultures of HIV-positive patients. Res Virol 144:69, 1993
16. + hematopoietic progenitors express low levels of CD4, the high-affinity receptor for human immunodeficiency virus-type 1. Blood 84:1896, 1994
17. Louache F, Debili N, Marandin A, Coulombel L, Vainchenker W: Expression of CD4 by human hematopoietic progenitors. Blood 84:3344, 1994
18. Andrews RG, Singer JW, Bernstein ID: Monoclonal antibody 12.8 recognizes a 115 Kd molecule present on both unipotent and multipotent hematopoietic differentiation antigens. Blood 67:842, 1986
19. Civin CI, Strauss LC, Brovall C, Fackler MJ, Schwartz JF, Sharper JH: Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. J Immunology 133:157, 1984
20. Watt S, Karhi K, Gatter K, Furley AJ, Katz FE, Healy LE, Altass LJ, Bradley NJ, Sutherland DR, Levinsky R, Greaves MF: Distribution and epitope analysis of cell surface membrane glycoprotein (HPCA-1) associated with human hematopoietic progenitor cells. Leukemia 1:417, 1986
21. Lansdorp PM, Dragowska W: Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow. J Exp Med 175:1501, 1992
22. + cells. Exp Hematol 20:1309, 1992
23. - progenitor cells. Blood 77:1218, 1991
24. Craig W, Kay R, Cutler RL, Lansdorp PM: Expression of Thy-1 on human hematopoietic progenitor cells. J Exp Med 177:1331, 1993
25. Sutherland HJ, Lansdorp PM, Henkelman DH, Eaves AC, Eaves CJ: Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. Proc Natl Acad Sci USA 87:3584, 1990
26. Coulombel L, Eaves AC, Eaves CJ: Enzymatic treatment of long-term human bone marrow cultures reveals the preferential location of primitive hemopoietic progenitors in the adherent layer. Blood 62:291, 1983
27. - progenitor cells in long-term cultures and semi-solid assays. Blood 81:2916, 1993
28. Siaki RK, Gelfand DH, Stoffel S, Scharf SJ, Higuchi R, Horn GT, Mullis KB, Erlich HA: Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239:487, 1988
29. Folks T, Powell D, Lightfoote M, Koenig S, Fauci A, Been S, Rabson A, Daugherty D, Gendelman H, Hoggan M, S. V, Martin M: Biological and biochemical characterization of a cloned Leu 3-cell surviving infection with the acquired immune deficiency syndrome retrovirus. J Exp Med 164:280, 1986
30. Andrews RG, Singer J, Bernstein ID: Precursors of colonyforming cells can be distinguished from colony-forming cells by expression of the CD33 and CD34 antigens and light scattering properties. J Exp Med 169:1721, 1989
31. + Thy-1+ Lin- subpopulation from mobilized peripheral blood. Blood 85:368, 1995
32. Baum CM, Weissman IM, Tsukamoto AS, Buckle AM, Peault B: Isolation of a candidate human hematopoietic stem-cell population. Proc Natl Acad Sci USA 89:2804, 1992
33. Terstappen LWMM, Hollander Z, Meiners H, Loken MR: Quantitative comparison of myeloid antigens on five lineages of mature peripheral blood cells. J Leuk Biol 48:138, 1990
34. + T cells is independent of transcription and translation. J Immunol 155:2902, 1995
35. Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA: CC CKR5: A Rantes, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272:1955, 1996
36. Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Hill CM, Davis CB, Peiper SC, Schall TJ, Littman DR, Landau NR: Identification of a major co-receptor for primary isolates of HIV-1, Nature 381:661, 1996
37. + cells is mediated by the chemokine receptor CC-CKR-5. Nature 381:667, 1996
38. Leiderman IZ, Greenberg ML, Adelsberg BR, Siegal FP: A glycoprotein inhibitor of in vitro granulopoiesis associated with AIDS. Blood 70:1267, 1987
39. Steinberg HN, Anderson J, Crumpacker CS, Chatis PA: HIV infection of the BS-1 human stromal cell line: Effect on murine hematopoiesis. Virology 193:524, 1993
40. Scadden DT, Zeira M, Woon A, Wang Z, Schieve L, Ikeuchi K, Lim B, Groopman JE: Human immunodeficiency virus infection of human bone marrow stromal fibroblasts. Blood 76:317, 1990
41. Schwartz GN, Kessler SW, Rothwell SW, Burrell LM, Reid TJ, Meltzer MS, Wright DG: Inhibitory effects of HIV-1-infected stromal cell layers on the production of myeloid progenitor cells in human long-term bone marrow cultures. Exp Hematol 22:1288, 1994
42. Marandin A, Canque B, Coulombel L, Gluckman JC, Vainchenker W, Louache F: In vitro infection of bone marrow-adherent cells by human immunodeficiency virus type 1 (HIV-1) does not alter their ability to support hematopoiesis. Virology 213:245, 1995
43. + hematopoietic progenitor cells by human immunodeficiency virus 1 or gp120 mediated by endogenous transforming growth factor β1. J Exp Med 183:99, 1996
44. Zauli G, Vitale M, Re MC, Furlini G, Zamai L, Falcieri E, Gibellini D, Visani G, Davis BR, Capitani S, La Placa M: In vitro exposure to human immunodeficiency virus type-1 (HIV-1) induces apoptotic cell death of the factor-dependent TF-1 hematopoietic cell line. Blood 83:167, 1994
45. Georgopoulos K, Bigby M, Wang J-H, Molnar A, Wu P, Winandy S, Sharpe A: The Ikaros gene is required for the development of all lymphoid lineages. Cell 79:143, 1994