Remifentanil

Drugs

Volumn 52, Issue 3, 1996, Pages 417-427

  Patel, S S ^a   Spencer, C M ^a   Glass, P S A ^a   Jones, R M ^a  

^a ADIS INTERNATIONAL LIMITED   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ALFENTANIL; MU OPIATE RECEPTOR; REMIFENTANIL;

ANALGESIA; ANALGESIC ACTIVITY; ANTINOCICEPTION; BRADYCARDIA; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG METABOLISM; DRUG POTENCY; DRUG STRUCTURE; FEVER; GENERAL ANESTHESIA; HEADACHE; HUMAN; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; LOCAL ANESTHESIA; MUSCLE RIGIDITY; NAUSEA; PAIN; POSTOPERATIVE ANALGESIA; PRURITUS; REGIONAL ANESTHESIA; RESPIRATION DEPRESSION; REVIEW; SHIVERING; VERTIGO; VISUAL DISORDER; VOMITING;

EID: 0029810464     PISSN: 00126667     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003495-199652030-00009     Document Type: Review

References (53)

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2. 2. P.S.A. Glass D. Hardman Y. Kamiyama 1993 Preliminary pharmaco-kinetics and pharmacodynamics of an ultra-short-acting opioid: remifentanil (GI87084B) Anesth Analg 77 1031 40 8105723 10.1213/00000539-199311000-00028 1:CAS:528:DyaK2cXis1Wit70%3D Glass PSA, Hardman D, Kamiyama Y, et al. Preliminary pharmacokinetics and pharmacodynamics of an ultra-short-acting opioid: remifentanil (GI87084B). Anesth Analg 1993 Nov; 77: 1031–40
3. 3. G.I. Randel R.J. Fragen E.S. Librojo 1994 Remifentanil blood concentration effect relationship at intubation and skin incision in surgical patients compared to alfentanil [abstract] Anesthesiology 81 A375 10.1097/00000542-199409001-00375 Randel GI, Fragen RJ, Librojo ES, et al. Remifentanil blood concentration effect relationship at intubation and skin incision in surgical patients compared to alfentanil [abstract]. Anesthesiology 1994 Sep; 81 Suppl.: A375
4. 4. T.G. Monk R. Batenhorst B. Jamerson 1995 Comparison of remifentanil and alfentanil concentrations with stress hormone responses during nitrous-narcotic anesthesia [abstract] Anesthesiology 83 A380 Monk TG, Batenhorst R, Jamerson B, et al. Comparison of remifentanil and alfentanil concentrations with stress hormone responses during nitrous-narcotic anesthesia [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A380
5. 5. T.D. Egan C.F. Minto D.J. Hermann 1996 Remifentanil versus alfentanil: comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers Anesthesiology 84 4 821 33 8638836 10.1097/00000542-199604000-00009 1:CAS:528:DyaK28Xis1Wntbw%3D Egan TD, Minto CF, Hermann DJ, et al. Remifentanil versus alfentanil: comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers. Anesthesiology 1996 Apr; 84(4): 821–33
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8. 8. M. Dershwitz G.I. Randel C.E. Rosow 1995 Initial clinical experience with remifentanil, a new opioid metabolized by esterases Anesth Analg 81 619 23 7653833 1:CAS:528:DyaK2MXos1Gmu78%3D Dershwitz M, Randel GI, Rosow CE, et al. Initial clinical experience with remifentanil, a new opioid metabolized by esterases. Anesth Analg 1995 Sep; 81: 619–23
9. 9. P.S. Sebel J.F. Hoke C. Westmoreland 1995 Histamine concentrations and hemodynamic responses after remifentanil Anesth Analg 80 5 990 3 7726445 1:STN:280:DyaK2M3ktlGhtg%3D%3D Sebel PS, Hoke JF, Westmoreland C, et al. Histamine concentrations and hemodynamic responses after remifentanil. Anesth Analg 1995 May; 80(5): 990–3
10. 10. M.C. Pitts M.M. Palmore M.T. Salmenpera 1992 Pilot study: hemodynamic effects of intravenous GI87084B (GI) in patients undergoing elective surgery [abstract] Anesthesiology 77 A101 10.1097/00000542-199209001-00101 Pitts MC, Palmore MM, Salmenpera MT, et al. Pilot study: hemodynamic effects of intravenous GI87084B (GI) in patients undergoing elective surgery [abstract]. Anesthesiology 1992 Sep; 77 Suppl.: A101
11. 11. D. Shlugman S. Dufore M. Dershwitz 1994 Respiratory effects of remifentanil in subjects with severe renal impairment compared to matched controls [abstract] Anesthesiology 81 A1417 10.1097/00000542-199409001-01417 Shlugman D, Dufore S, Dershwitz M, et al. Respiratory effects of remifentanil in subjects with severe renal impairment compared to matched controls [abstract]. Anesthesiology 1994 Sep; 81 Suppl.: A1417
12. 12. M. Dershwitz J.F. Hoke C.E. Rosow 1996 Pharmacokinetics and pharmacodynamics of remifentanil in volunteer subbjects with severe liver disease Anesthesiology 84 4 812 20 8638835 10.1097/00000542-199604000-00008 1:CAS:528:DyaK28Xis1Wntb8%3D Dershwitz M, Hoke JF, Rosow CE, et al. Pharmacokinetics and pharmacodynamics of remifentanil in volunteer subbjects with severe liver disease. Anesthesiology 1996 Apr; 84(4): 812–20
13. 13. H.M. Amin A.M. Sopchak B.F. Esposito 1995 Naloxone-induced and spontaneous reversal of depressed ventilatory responses to hypoxia during and after continuous infusion of remifentanil or alfentanil J Pharmacol Exp Ther 274 1 34 9 7616418 1:CAS:528:DyaK2MXntVWls7Y%3D Amin HM, Sopchak AM, Esposito BF, et al. Naloxone-induced and spontaneous reversal of depressed ventilatory responses to hypoxia during and after continuous infusion of remifentanil or alfentanil. J Pharmacol Exp Ther 1995 Jul; 274(1): 34–9
14. 14. K.Z. Baker N. Ostapkovich T. Jackson 1995 Cerebral blood flow reactivity is intact during remifentanil/N 2 O anesthesia [abstract] Anesth Analg 80 S27 Baker KZ, Ostapkovich N, Jackson T, et al. Cerebral blood flow reactivity is intact during remifentanil/N 2 O anesthesia [abstract]. Anesth Analg 1995 Feb; 80 Suppl.: S27
15. 15. J. Guy D.S. Wamer J. Kirchner 1996 ICP effects and emergence/recovery profile of neurosurgical patients following remifentanil/ N 2 O anesthesia [abstract] Anesth Analg 82 S151 Guy J, Wamer DS, Kirchner J, et al. ICP effects and emergence/recovery profile of neurosurgical patients following remifentanil/ N 2 O anesthesia [abstract]. Anesth Analg 1996 Feb; 82 Suppl.: S151
16. 16. B. Hindman D. Warner M. Todd 1994 ICP and CPP effects of remifentanil and alfentanil [abstract] J Neurosurg Anesthesiol 6 4 304 Hindman B, Warner D, Todd M, et al. ICP and CPP effects of remifentanil and alfentanil [abstract]. J Neurosurg Anesthesiol 1994; 6(4): 304
17. 17. K. Moore M.B. Howie M.W. Jopling 1995 EEG characteristics during continuous infusion of remifentanil for CABG surgery [abstract] Anesthesiology 83 A377 10.1097/00000542-199512000-00037 Moore K, Howie MB, Jopling MW, et al. EEG characteristics during continuous infusion of remifentanil for CABG surgery [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A377
18. 18. I. Crabb C. Thornton K.M. Konieczko 1996 Remifentanil reduces auditory and somatosensory evoked responses during isoflurane anaesthesia in a dose-dependent manner Br J Anaesth 76 795 801 8679352 10.1093/bja/76.6.795 1:CAS:528:DyaK28XksFeisLc%3D Crabb I, Thornton C, Konieczko KM, et al. Remifentanil reduces auditory and somatosensory evoked responses during isoflurane anaesthesia in a dose-dependent manner. Br J Anaesth 1996; 76: 795–801
19. 19. T.D. Egan H.J.M. Lemmens P. Fiset 1993 The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers Anesthesiology 79 5 881 92 7902032 10.1097/00000542-199311000-00004 1:CAS:528:DyaK2cXmvFequw%3D%3D Egan TD, Lemmens HJM, Fiset P, et al. The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers. Anesthesiology 1993 Nov; 79(5): 881–92
20. 20. C.L. Westmoreland J.F. Hoke P.S. Sebel 1993 Pharmacokinetics of remifentanil (GI87084B) and its major metabolite (GI90291) in patients undergoing elective inpatient surgery Anesthesiology 79 5 893 903 7902033 10.1097/00000542-199311000-00005 1:CAS:528:DyaK2cXmvFCjsg%3D%3D Westmoreland CL, Hoke JF, Sebel PS, et al. Pharmacokinetics of remifentanil (GI87084B) and its major metabolite (GI90291) in patients undergoing elective inpatient surgery. Anesthesiology 1993 Nov; 79(5): 893–903
21. 21. T.D. Egan V. Billard J. Barr 1995 Gender has no effect on the pharmacokinetics or pharmacodynamics of remifentanil [abstract] Anesthesiology 83 A325 10.1097/00000542-199508000-00013 Egan TD, Billard V, Barr J, et al. Gender has no effect on the pharmacokinetics or pharmacodynamics of remifentanil [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A325
22. 22. T.D. Egan S.K. Gupta R.J. Sperry 1995 The pharmacokinetics of remifentanil in obese versus lean elective surgery patients [abstract] Anesth Analg 82 S100 Egan TD, Gupta SK, Sperry RJ, et al. The pharmacokinetics of remifentanil in obese versus lean elective surgery patients [abstract]. Anesth Analg 1995; 82: S100
23. 23. L.G. Michelsen J.F. Hoke C.C. Hug 1995 Pharmacokinetics of remifentanil in cardiac surgical patients [abstract] Anesthesiology 83 A379 Michelsen LG, Hoke JF, Hug CC, et al. Pharmacokinetics of remifentanil in cardiac surgical patients [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A379
24. 24. D. Royston S. Gupta A. Haigh 1995 The pharmacokinetics of remifentanil injection during hypothermic cardiopulmonary bypass in humans [abstract] Anesthesiology 83 A384 Royston D, Gupta S, Haigh A, et al. The pharmacokinetics of remifentanil injection during hypothermic cardiopulmonary bypass in humans [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A384
25. 25. P.J. Davis A. Ross R.L. Stiller 1995 Pharmacokinetics of remifentanil in anesthetized children 2-12 years of age [abstract] Anesth Analg 80 S93 10.1213/00000539-199504001-00004 Davis PJ, Ross A, Stiller RL, et al. Pharmacokinetics of remifentanil in anesthetized children 2-12 years of age [abstract]. Anesth Analg 1995 Feb; 80 Suppl.: S93
26. 26. R.L. Stiller P.J. Davis F.X. McGowan 1995 In vitro metabolism of remifentanil: the effects of pseudocholinesterase deficiency [abstract] Anesthesiology 83 A381 Stiller RL, Davis PJ, McGowan FX, et al. In vitro metabolism of remifentanil: the effects of pseudocholinesterase deficiency [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A381
27. 27. K. Selinger R.L. Nation G.A. Smith 1995 Enzymatic and chemical hydrolysis of remifentanil [abstract] Anesthesiology 83 A385 Selinger K, Nation RL, Smith GA. Enzymatic and chemical hydrolysis of remifentanil [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A385
28. 28. F.E. Cunningham J.F. Hoke K.T. Muir 1995 Pharmacokinetic/pharmacodynamic evaluation of remifentanil, GR90291, and alfentanil [abstract] Anesthesiology 83 A376 Cunningham FE, Hoke JF, Muir KT, et al. Pharmacokinetic/pharmacodynamic evaluation of remifentanil, GR90291, and alfentanil [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A376
29. 29. T.D. Egan 1995 Remifentanil pharmacokinetics and pharmacodynamics: a preliminary appraisal Clin Pharmacokinet 29 80 94 7586903 10.2165/00003088-199529020-00003 1:CAS:528:DyaK2MXnsV2ksbk%3D Egan TD. Remifentanil pharmacokinetics and pharmacodynamics: a preliminary appraisal. Clin Pharmacokinet 1995 Aug; 29: 80–94
30. 30. J.F. Hoke K.T. Muir P.S.A. Glass 1995 Pharmacokinetics (PK) of remifentanil (R) and its metabolite (GR90291) in subjects with renal disease [abstract no. PI-55] Clin Pharmacol Ther 57 2 148 Hoke JF, Muir KT, Glass PSA, et al. Pharmacokinetics (PK) of remifentanil (R) and its metabolite (GR90291) in subjects with renal disease [abstract no. PI-55]. Clin Pharmacol Ther 1995 Feb; 57(2): 148
31. 31. V.U. Navapurkar S. Archer N.M. Frazer 1995 Pharmacokinetics of remifentanil during hepatic transplantation [abstract] Anesthesiology 83 A382 10.1097/00000542-199508000-00019 Navapurkar VU, Archer S, Frazer NM, et al. Pharmacokinetics of remifentanil during hepatic transplantation [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A382
32. 32. A. Kovac S. Azad R. Batenhorst 1995 Remifentanil versus alfentanil balanced anesthesia for total abdominal hysterectomy [abstract] Anesthesiology 83 A383 Kovac A, Azad S, Batenhorst R, et al. Remifentanil versus alfentanil balanced anesthesia for total abdominal hysterectomy [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A383
33. 33. T.G. Monk R.L. Batenhorst W.H. Folger 1994 A comparison of remifentanil and alfentanil during nitrous-narcotic anesthesia [abstract] Anesth Analg 78 S293 10.1213/00000539-199402000-00016 Monk TG, Batenhorst RL, Folger WH, et al. A comparison of remifentanil and alfentanil during nitrous-narcotic anesthesia [abstract]. Anesth Analg 1994 Feb; 78 Suppl.: S293
34. 34. S.K. Kallar T.W. Hurt V. Wetchler 1994 A single blind, comparative study of the safety and efficacy of remifentanil and alfentanil for outpatient anesthesia [abstract] Anesthesiology 81 A32 10.1097/00000542-199409001-00032 Kallar SK, Hurt TW, Wetchler V, et al. A single blind, comparative study of the safety and efficacy of remifentanil and alfentanil for outpatient anesthesia [abstract]. Anesthesiology 1994 Sep; 81 Suppl.: A32
35. 35. J. Schüttler C. Prys-Roberts H. Breivik 1996 A double-blind, randomised comparison of remifentanil and alfentanil in patients undergoing major abdominal surgery [abstract no. P619] Proceedings of the 11th World Congress of Anaesthesiologists Sydney, Australia 388 Schüttler J, Prys-Roberts C, Breivik H, et al. A double-blind, randomised comparison of remifentanil and alfentanil in patients undergoing major abdominal surgery [abstract no. P619]. Proceedings of the 11th World Congress of Anaesthesiologists; 1996 Apr 14-20; Sydney, Australia, 388.
36. 36. D.P. Cartwright J.-P. Jansen O. Kvalsvik 1996 Double-blind, randomised comparison of remifentanil and alfentanil in out-patient surgery [abstract no. P644] Proceedings of the 11th World Congress of Anaesthesiologists Sydney, Australia 397 Cartwright DP, Jansen J-P, Kvalsvik O, et al. Double-blind, randomised comparison of remifentanil and alfentanil in out-patient surgery [abstract no. P644]. Proceedings of the 11th World Congress of Anaesthesiologists; 1996 Apr 14-20; Sydney, Australia, 397
37. 37. I.T. Munday P.M. Ward S. Sorooshian 1995 Interaction between remifentanil and isoflurane in spontaneously breathing patients during ambulatory surgery [abstract] Anesthesiology 83 A23 10.1097/00000542-199507000-00004 Munday IT, Ward PM, Sorooshian S, et al. Interaction between remifentanil and isoflurane in spontaneously breathing patients during ambulatory surgery [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A23
38. 38. J. Peacock C. Reilly J. Luntley 1995 Remifentanil in combination with propofol for spontaneous ventilation anaesthesia [abstract] Anesthesiology 83 A35 Peacock J, Reilly C, Luntley J, et al. Remifentanil in combination with propofol for spontaneous ventilation anaesthesia [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A35
39. 39. T. Witkowski S.S. Azad J. Lessin 1995 Recovery following remifentanil for prolonged operations: a comparison with alfentanil [abstract] Anesthesiology 83 A378 Witkowski T, Azad SS, Lessin J, et al. Recovery following remifentanil for prolonged operations: a comparison with alfentanil [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A378
40. 40. C. Hogue E. Camporesi D. Duncalf 1995 Total intravenous anesthesia with remifentanil and propofol in patients undergoing elective inpatient surgery [abstract] Anesthesiology 83 A386 Hogue C, Camporesi E, Duncalf D, et al. Total intravenous anesthesia with remifentanil and propofol in patients undergoing elective inpatient surgery [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A386
41. 41. B.K. Philip P.E. Scuder F. Chung 1995 Comparison of remifentanil/propofol to alfentanil/propofol for laparoscopic outpatient surgery [abstract] Anesthesiology 83 3A A3 Philip BK, Scuder PE, Chung F, et al. Comparison of remifentanil/propofol to alfentanil/propofol for laparoscopic outpatient surgery [abstract]. Anesthesiology 1995 Sep; 83(3A) Suppl.: A3
42. 42. F. Chung 1993 Are discharge criteria changing? J Clin Anesth 5 6 64S 8S 8292372 10.1016/0952-8180(93)90011-3 1:STN:280:DyaK2c7itF2gsg%3D%3D Chung F. Are discharge criteria changing? J Clin Anesth 1993 Nov/Dec; 5(6) Suppl. 1: 64S–8S
43. 43. R.J. Fragen G.I. Randel E.S. Librojo 1994 The interaction of remifentanil and propofol to prevent response to tracheal intubation and the start of surgery for outpatient knee arthroscopy [abstract] Anesthesiology 81 A376 10.1097/00000542-199409001-00375 Fragen RJ, Randel GI, Librojo ES, et al. The interaction of remifentanil and propofol to prevent response to tracheal intubation and the start of surgery for outpatient knee arthroscopy [abstract]. Anesthesiology 1994 Sep; 81 Suppl.: A376
44. 44. A. Kapila E. Lang P. Glass 1994 MAC reduction of isoflurane by remifentanil [abstract] Anesthesiology 81 A378 10.1097/00000542-199409001-00378 Kapila A, Lang E, Glass P, et al. MAC reduction of isoflurane by remifentanil [abstract]. Anesthesiology 1994 Sep; 81 Suppl.: A378
45. 45. M. Mingus M. Rosenblatt D. Gainsburg 1996 Comparison of remifentanil and propofol as adjuncts to peripheral regional anesthesia for ambulatory surgery [abstract] Anesth Analg 82 S319 Mingus M, Rosenblatt M, Gainsburg D, et al. Comparison of remifentanil and propofol as adjuncts to peripheral regional anesthesia for ambulatory surgery [abstract]. Anesth Analg 1996 Feb; 82 Suppl.: S319
46. 46. T.G. Monk D.D. Pulley W.L. Jenkins 1996 Comparison of remifentanil and propofol as adjuncts to spinal anesthesia [abstract] Anesth Analg 82 S321 Monk TG, Pulley DD, Jenkins WL, et al. Comparison of remifentanil and propofol as adjuncts to spinal anesthesia [abstract]. Anesth Analg 1996; 82: S321
47. 47. I. Smith M. Avramov P.F. White 1995 Remifentanil versus propofol for monitored anesthesia care in the ambulatory setting [abstract] Anesthesiology 83 A5 Smith I, Avramov M, White PF. Remifentanil versus propofol for monitored anesthesia care in the ambulatory setting [abstract]. Anesthesiology 1995 Sep; 83 Suppl.: A5
48. 48. M. Avramov I. Smith P.F. White 1995 Use of midazolam and remifentanil during monitored anesthesia care (MAC) [abstract] Anesth Analg 80 S24 Avramov M, Smith I, White PF. Use of midazolam and remifentanil during monitored anesthesia care (MAC) [abstract]. Anesth Analg 1995 Feb; 80 Suppl.: S24
49. 49. P.R. Reese P.F. White J.T. Lee 1996 Remifentanil vs midazolam-remifentanil for monitored anesthesia care: anesthesiologist’s assessment and patient satisfaction [abstract] Anesth Analg 82 S374 Reese PR, White PF, Lee JT, et al. Remifentanil vs midazolam-remifentanil for monitored anesthesia care: anesthesiologist’s assessment and patient satisfaction [abstract]. Anesth Analg 1996; 82: S374
50. 50. T. Witkowski S.S. Azad J. Lessin 1995 Post-op analgesia with remifentanil: dosage and side effects [abstract] Anesth Analg 80 S554 Witkowski T, Azad SS, Lessin J, et al. Post-op analgesia with remifentanil: dosage and side effects [abstract]. Anesth Analg 1995 Feb; 80 Suppl.: S554
51. 51. J. Yarmush R. D’Angelo C. O’Leary 1996 Remifentanil vs morphine for acute postoperative analgesia [abstract] Anesth Analg 82 S504 Yarmush J, D’Angelo R, O’Leary C, et al. Remifentanil vs morphine for acute postoperative analgesia [abstract]. Anesth Analg 1996 Feb; 82 Suppl.: S504
52. 52. F. Camu J.R. Sneyd D. Holgersen 1996 Efficacy and safety of remifentanil to control immediate post-operative pain prior to transfer to ward analgesia [abstract no. D311] Proceedings of the 11th World Congress of Anaesthesiologists Sydney, Australia 285 Camu F, Sneyd JR, Holgersen D, et al. Efficacy and safety of remifentanil to control immediate post-operative pain prior to transfer to ward analgesia [abstract no. D311]. Proceedings of the 11th World Congress of Anaesthesiologists; 1996 Apr 14-20; Sydney, Australia, 285.
53. 53. GlaxoWellcome Inc. RTP North Carolina. Product information: Ultiva (remifentanil hydrochloride).