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Volumn 87, Issue 7, 1996, Pages 2641-2648

Extracellular truncations of hβc, the common signaling subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-5, lead to ligand-independent activation

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 5; LIGAND; VIRUS DNA;

EID: 0029925333     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.7.2641.bloodjournal8772641     Document Type: Article
Times cited : (25)

References (42)
  • 1
    • 0025162844 scopus 로고
    • Structural design and molecular evolution of a cytokine receptor superfamily
    • Bazan JF: Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA 87:6934, 1990
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6934
    • Bazan, J.F.1
  • 2
    • 0025740304 scopus 로고
    • The cytokine receptor superfamily
    • Kaczmarski RS, Mufti GJ: The cytokine receptor superfamily. Blood Rev 5:193, 1991
    • (1991) Blood Rev , vol.5 , pp. 193
    • Kaczmarski, R.S.1    Mufti, G.J.2
  • 3
    • 0026598960 scopus 로고
    • Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
    • de Vos AM, Ultsch M, Kossiakoff AA: Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex. Science 255:306, 1992
    • (1992) Science , vol.255 , pp. 306
    • De Vos, A.M.1    Ultsch, M.2    Kossiakoff, A.A.3
  • 4
    • 0028032203 scopus 로고
    • The x-ray structure of a growth hormone-prolactin receptor complex
    • Somers W, Ultsch M, de Vos AM, Kossiakoff AA: The x-ray structure of a growth hormone-prolactin receptor complex. Nature 372:478, 1994
    • (1994) Nature , vol.372 , pp. 478
    • Somers, W.1    Ultsch, M.2    De Vos, A.M.3    Kossiakoff, A.A.4
  • 6
    • 0025861158 scopus 로고
    • Functional domains of the granulocyte colony-stimulating factor receptor
    • Fukunaga R, Ishizaka-Ikeda E, Pan CX, Seto Y, Nagata S: Functional domains of the granulocyte colony-stimulating factor receptor. EMBO J 10:2855, 1991
    • (1991) EMBO J , vol.10 , pp. 2855
    • Fukunaga, R.1    Ishizaka-Ikeda, E.2    Pan, C.X.3    Seto, Y.4    Nagata, S.5
  • 7
    • 0027443453 scopus 로고
    • The proline-rich motif (PRM): A novel feature of the cytokine/hematopoietin receptor superfamily
    • O'Neal KD, Yu Lee LY: The proline-rich motif (PRM): A novel feature of the cytokine/hematopoietin receptor superfamily. Lymphokine Cytokine Res 12:309, 1993
    • (1993) Lymphokine Cytokine Res , vol.12 , pp. 309
    • O'Neal, K.D.1    Yu Lee, L.Y.2
  • 8
    • 0028277888 scopus 로고
    • Characterization of Mpl cytoplasmic domain sequences required for myeloproliferative leukemia virus pathogenicity
    • Benit L, Courtois G, Charon M, Varlet P, Dusanter Fourt I, Gisselbrecht S: Characterization of Mpl cytoplasmic domain sequences required for myeloproliferative leukemia virus pathogenicity. J Virol 68:5270, 1994
    • (1994) J Virol , vol.68 , pp. 5270
    • Benit, L.1    Courtois, G.2    Charon, M.3    Varlet, P.4    Dusanter Fourt, I.5    Gisselbrecht, S.6
  • 10
    • 0028845212 scopus 로고
    • Cytokine receptor signalling
    • Ihle J: Cytokine receptor signalling. Nature 377; 591, 1995
    • (1995) Nature , vol.377 , pp. 591
    • Ihle, J.1
  • 11
    • 0025674093 scopus 로고
    • A putative truncated cytokine receptor gene transduced by the myeloproliferative leukaemia virus immortalises hematopoietic progenitors
    • Souyri M, Vigor I, Penciolelli J-F, Heard J-M, Tambourin P, Wendling F: A putative truncated cytokine receptor gene transduced by the myeloproliferative leukaemia virus immortalises hematopoietic progenitors. Cell 63:1137, 1990
    • (1990) Cell , vol.63 , pp. 1137
    • Souyri, M.1    Vigor, I.2    Penciolelli, J.-F.3    Heard, J.-M.4    Tambourin, P.5    Wendling, F.6
  • 17
    • 0028832719 scopus 로고
    • Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity
    • Alexander WS, Metcalf D, Dunn AR: Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity. EMBO J 14:5569, 1995
    • (1995) EMBO J , vol.14 , pp. 5569
    • Alexander, W.S.1    Metcalf, D.2    Dunn, A.R.3
  • 19
    • 0026326555 scopus 로고
    • An activating mutation in the murine erythropoietin receptor induces erythroleukaemia in mice: A cytokine receptor superfamily oncogene
    • Longmore GD, Lodish HF: An activating mutation in the murine erythropoietin receptor induces erythroleukaemia in mice: A cytokine receptor superfamily oncogene. Cell 67:1089, 1991
    • (1991) Cell , vol.67 , pp. 1089
    • Longmore, G.D.1    Lodish, H.F.2
  • 20
    • 0028332086 scopus 로고
    • Activation and inhibition of erythropoietin receptor function: Role of receptor dimerization
    • Watowich SS, Hilton DJ, Lodish HF: Activation and inhibition of erythropoietin receptor function: role of receptor dimerization. Mol Cell Biol 14:3535, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 3535
    • Watowich, S.S.1    Hilton, D.J.2    Lodish, H.F.3
  • 21
    • 0029151003 scopus 로고
    • Activating point mutations in the common β subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of β subunit dimerisation and cell type specific molecules in signalling
    • Jenkins BJ, D'Andrea R, Gonda TJ: Activating point mutations in the common β subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of β subunit dimerisation and cell type specific molecules in signalling. EMBO J 14:4276, 1995
    • (1995) EMBO J , vol.14 , pp. 4276
    • Jenkins, B.J.1    D'Andrea, R.2    Gonda, T.J.3
  • 23
    • 0024505028 scopus 로고
    • A point mutation in the neu oncogene mimics ligand induction of receptor aggregation
    • Weiner DB, Liu J, Cohen JA, Williams WV, Greene MI: A point mutation in the neu oncogene mimics ligand induction of receptor aggregation. Nature 339:230, 1989
    • (1989) Nature , vol.339 , pp. 230
    • Weiner, D.B.1    Liu, J.2    Cohen, J.A.3    Williams, W.V.4    Greene, M.I.5
  • 25
    • 0028274280 scopus 로고
    • A mutation of the common receptor subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor, and IL-5 that leads to ligand independence and tumorigenicity
    • D'Andrea R, Rayner J, Moretti P, Lopez A, Goodall GJ, Gonda TJ, Vadas MA: A mutation of the common receptor subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor, and IL-5 that leads to ligand independence and tumorigenicity. Blood 83:2802, 1994
    • (1994) Blood , vol.83 , pp. 2802
    • D'Andrea, R.1    Rayner, J.2    Moretti, P.3    Lopez, A.4    Goodall, G.J.5    Gonda, T.J.6    Vadas, M.A.7
  • 26
    • 0028078578 scopus 로고
    • A simple and efficient procedure for generating stable expression libraries by cDNA cloning in a retroviral vector
    • Rayner JR, Gonda TJ: A simple and efficient procedure for generating stable expression libraries by cDNA cloning in a retroviral vector. Mol Cell Biol 14:880, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 880
    • Rayner, J.R.1    Gonda, T.J.2
  • 27
    • 0020582124 scopus 로고
    • Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus
    • Mann R, Mulligan RC, Baltimore D: Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell 33:153, 1983
    • (1983) Cell , vol.33 , pp. 153
    • Mann, R.1    Mulligan, R.C.2    Baltimore, D.3
  • 29
    • 0024836051 scopus 로고
    • A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalisation
    • Hatakeyama M, Mori H, Doi T, Taniguchi T: A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalisation. Cell 59:837, 1989
    • (1989) Cell , vol.59 , pp. 837
    • Hatakeyama, M.1    Mori, H.2    Doi, T.3    Taniguchi, T.4
  • 30
    • 0022401521 scopus 로고
    • Expression of a haemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity
    • Lang RA, Metcalf D, Gough NM, Dunn AR, Gonda TJ: Expression of a haemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity. Cell 43:531, 1985
    • (1985) Cell , vol.43 , pp. 531
    • Lang, R.A.1    Metcalf, D.2    Gough, N.M.3    Dunn, A.R.4    Gonda, T.J.5
  • 31
    • 0018698577 scopus 로고
    • Heterogeneity of genetic loci in chickens: Analysis of endogenous viral and normal genes by cleavage of DNA with restriction endonucleases
    • Hughes SH, Payvar F, Spector D, Schimke RT, Robinson HL, Payne GS, Bishop JM, Varmus HE: Heterogeneity of genetic loci in chickens: analysis of endogenous viral and normal genes by cleavage of DNA with restriction endonucleases. Cell 18:347, 1979
    • (1979) Cell , vol.18 , pp. 347
    • Hughes, S.H.1    Payvar, F.2    Spector, D.3    Schimke, R.T.4    Robinson, H.L.5    Payne, G.S.6    Bishop, J.M.7    Varmus, H.E.8
  • 32
    • 0002437098 scopus 로고
    • Amplification of genomic DNA
    • Innes MA, Gelfand DH, Sninsky JJ, White TJ (eds): San Diego, CA, Academic
    • Saiki RK: Amplification of genomic DNA, in Innes MA, Gelfand DH, Sninsky JJ, White TJ (eds): PCR Protocols: A Guide to Methods and Applications. San Diego, CA, Academic, 1990, p 13
    • (1990) PCR Protocols: A Guide to Methods and Applications , pp. 13
    • Saiki, R.K.1
  • 33
    • 0025637605 scopus 로고
    • Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): Reconstitution of a high-affinity GM-CSF receptor
    • Hayashida K, Kitamura T, Gorman DM, Arai K, Yokota T, Miyajima A: Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): Reconstitution of a high-affinity GM-CSF receptor. Proc Natl Acad Sci USA 87:9655, 1990
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9655
    • Hayashida, K.1    Kitamura, T.2    Gorman, D.M.3    Arai, K.4    Yokota, T.5    Miyajima, A.6
  • 34
    • 0025861759 scopus 로고
    • Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors
    • Kitamura T, Sato N, Arai K, Miyajima A: Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Cell 66:1165, 1991
    • (1991) Cell , vol.66 , pp. 1165
    • Kitamura, T.1    Sato, N.2    Arai, K.3    Miyajima, A.4
  • 36
    • 0025770219 scopus 로고
    • Human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF
    • Tavernier J, Devos R, Cornelis S, Tuypens T, Van der Heyden J, Fiers W, Plaetinck G: Human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF. Cell 66:1175, 1991
    • (1991) Cell , vol.66 , pp. 1175
    • Tavernier, J.1    Devos, R.2    Cornelis, S.3    Tuypens, T.4    Van Der Heyden, J.5    Fiers, W.6    Plaetinck, G.7
  • 37
    • 0024846310 scopus 로고
    • Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor
    • Gearing DP, King JA, Gough NM, Nicola NA: Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor. EMBO J 8:3667, 1989
    • (1989) EMBO J , vol.8 , pp. 3667
    • Gearing, D.P.1    King, J.A.2    Gough, N.M.3    Nicola, N.A.4
  • 39
    • 0028005446 scopus 로고
    • Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF
    • Woodcock JM, Zacharakis B, Plaetinck G, Bagley CJ, Qiyu S, Hercus TR, Tavernier J, Lopez AF: Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J 13:5176, 1995
    • (1995) EMBO J , vol.13 , pp. 5176
    • Woodcock, J.M.1    Zacharakis, B.2    Plaetinck, G.3    Bagley, C.J.4    Qiyu, S.5    Hercus, T.R.6    Tavernier, J.7    Lopez, A.F.8
  • 41
    • 0028945520 scopus 로고
    • High affinity chimeric human GM-CSF receptor carrying the cytoplasmic domain of the β subunit but not the α subunit transduces growth promoting signals in Ba/F3 cells
    • Muto A, Watanabe S, Miyajima A, Yokota T, Arai K-I: High affinity chimeric human GM-CSF receptor carrying the cytoplasmic domain of the β subunit but not the α subunit transduces growth promoting signals in Ba/F3 cells. Biochem Biophys Res Commun 208:368, 1995
    • (1995) Biochem Biophys Res Commun , vol.208 , pp. 368
    • Muto, A.1    Watanabe, S.2    Miyajima, A.3    Yokota, T.4    Arai, K.-I.5
  • 42
    • 0028097543 scopus 로고
    • A low affinity chimeric human α/β-GM-CSF receptor induces ligand dependent proliferation in a murine cell line
    • Eder M, Ernst TJ, Ganser A, Jubinsky PT, Inborn R, Hoelzer D, Griffin JD: A low affinity chimeric human α/β-GM-CSF receptor induces ligand dependent proliferation in a murine cell line. J Biol Chem 269:30173, 1994
    • (1994) J Biol Chem , vol.269 , pp. 30173
    • Eder, M.1    Ernst, T.J.2    Ganser, A.3    Jubinsky, P.T.4    Inborn, R.5    Hoelzer, D.6    Griffin, J.D.7


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