Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas- kidney transplant recipients: Dose-response effects of insulin on glucose turnover

Diabetes

Volumn 45, Issue 9, 1996, Pages 1267-1275

  Christiansen, Erik ^a,b   Vestergaard, Henrik ^b   Tibell, Annika ^a   Hother Nielsen, Ole ^c   Holst, Jens Juul ^d   Pedersen, Oluf ^c   Madsbad, Sten ^e  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b STENO DIABETES CENTER   (Denmark)

^c ODENSE UNIVERSITY HOSPITAL   (Denmark)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CALORIMETRY; CLINICAL ARTICLE; DOSE RESPONSE; ENZYME ACTIVITY; FEMALE; GLUCOSE METABOLISM; GLUCOSE OXIDATION; HUMAN; INSULIN METABOLISM; INSULIN RESISTANCE; INSULINEMIA; KIDNEY TRANSPLANTATION; MALE; PANCREAS TRANSPLANTATION; PATIENT COMPLIANCE; PRIORITY JOURNAL; STEADY STATE; TREATMENT PLANNING;

EID: 0029795430     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.9.1267     Document Type: Article

References (52)

1. Blackard WG, Nelson NC: Portal and peripheral vein immunoreactive insulin concentrations before and after glucose infusions. Diabetes 19:302-306, 1970
2. Elahi D, Clark BA, McAloon-Dyke M, Wong G, Brown R, Shapiro M, Minaker KL, Flanagan TL, Pruett T, Gingerich R, Hanks J, Andersen DK: Islet cell responses to glucose in human transplanted pancreas. Am J Physiol 261:E800-E808, 1991
3. Luzi L, Secchi A, Facchini F, Battezzali A, Staudacher C, Spotti D, Ferrari G, Di Carlo V, Pozza G: Reduction of insulin resistance by combined kidney-pancreas transplantation in type 1 (insulin-dependent) diabetic patients. Diabetologia 33:549-556, 1990
4. Diem P, Abid M, Redmon JB, Sutherland DER, Robertson RP: Systemic venous drainage of pancreas allografts as independent cause of hyperinsulinemia in type 1 diabetic recipients. Diabetes 39:534-540, 1990
5. Christiansen E, Andersen HB, Rasmussen K, Christensen NJ, Olgaard K, Kirkegaard P, Tronier T, Vølund A, Damsbo P, Burcharth F, Madsbad S: Pancreatic β-cell function and glucose metabolism in human pancreas and kidney transplantation. Am J Physiol 264:E441-E449, 1993
6. Christiansen E, Tibell A, Vølund A, Rasmussen K, Tydén G, Pedersen O, Christensen NJ, Madsbad S: Insulin secretion, insulin action and non-insulin-dependent glucose uptake in pancreas transplant recipients. J Clin Endocrinol Metab 79:15(31-1569, 1994
7. Rizza RA, Mandarino U, Gerich JE: Cortisol-induced insulin resistance in man: impaired suppression of glucose production and stimulation of glucose utilization due to a postreceptor defect of insulin action. J Clin Endocrinol Metab 54:131-138, 1982
8. Nosadini R, Del Prato S, Tiengo A, Valerio A, Muggeo M, Opocher G, Manetro F, Duner E, Marescotti C, Mollo F, Belloni F: Insulin resistance in Cushing' syndrome. J Clin Endocrinol Metab 57:529-536, 1983
9. Campbell PJ, Mandarino LJ, Gerich JE: Quantification of the relative impairments in actions of insulin on hepatic glucose production and peripheral glucose uptake in non-insulin-dependent diabetes mellitus. Metabolism 37:15-21, 1988
10. Katz H, Butler P, Homan M, Zerman A, Caumo A, Cobelli, Rizza R: Hepatic and extrahepatic insulin action in humans: measurements in the absence of non-steady-state error. Am J Physiol 264:E561-E566, 1993
11. Hother-Nielsen O, Henriksen JE, Holst JJ, Beck-Nielsen H: Effects of insulin on glucose turnover rates in vivo: isotope dilution versus constant specific activity technique. Metabolism 45:1-10, 1996
12. Turk D, Alzaid A, Dinneen S, Nair KS, Rizza R: The effects of non-insulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues. J Clin Invest 95:755-762, 1995
13. Rizza RA, Mandarino LJ, Gerich JE: Dose-response characteristics for effects of insulin on production and utilization of glucose in man. Am J Physiol 240:E630-E639, 1981
14. Rooney DP, Robertson RP: Hepatic insulin resistance after pancreas transplantation in type I diabetes. Diabetes 45:134-138, 1996
15. DeFronzo RA, Jacot E, Jequier E, Maeder E, Wahren J, Felber JP: The effect of insulin on the disposal of intravenous glucose: results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 30:1000-1007, 1981
16. Bogardus C, Lillioja S, Stone K, Mott DM: Correlation between muscle glycogen synthase activity and in vivo insulin action in man. J Clin Invest 73:1185-1190, 1984
17. Bergman RN, Hope ID, Yang YJ, Watanabe RM, Meador MA, Youn JH, Ader M: Assessment of insulin sensitivity in vivo: a critical review. Diabetes Metab Ren 5:411-429, 1989
18. Sherwin RS, Kramer KJ, Tobin JD, Insel PA, Liljenquist JE, Berman M, Andres R: A model of the kinetics of insulin in man. J Clin Invest 53:1481-1492, 1974
19. 3H]-glucose infusion and labelled or unlabelled glucose infusates. Diabetic Med 9:840-849, 1992
20. Jeng CY, Sheu WH-H, Fuh MM-T, Chen Y-DI, Reaven GM: Relationship between hepatic glucose production and fasting plasma glucose concentration in patients with NIDDM. Diabetes 43:1440-1444, 1994
21. Steele R: Influence of glucose loading and of injected insulin on the hepatic glucose output. Ann NY Acad Sci 82:420-430, 1959
22. Cowan JS, Hetenyi G: Glucoregulatory responses in normal and diabetic dogs recorded by a new tracer method. Metabolism 20:360-372, 1971
23. Insel PA, Liljenquist JE, Tobin JD, Sherwin RS, Watkins P, Andres R, Bergman M: Insulin control of glucose metabolism in man: a kinetic analysis. J Clin Invest 55:1057-1066, 1975
24. Hother-Nielsen O, Schmilz O, Bak JF, Beck-Nielsen H: Enhanced insulin sensitivity, but peripheral insulin resistance in patients with type I (insulin-dependent) diabetes. Diabetologia 30:834-840, 1987
25. De Feo, Perriello G, De Cosmo S, Ventura MM, Campbell PJ, Brunetti P, Gerich JE, Bolli GB: Comparison of glucose counterregulation during short-term and prolonged hypoglycemia in normal humans. Diabetes 35:563-569, 1986
26. Adkins-Marshall B, Pagliasotti MJ, Asher JR, Connolly CC, Neal DW, Meyers PE, Hendrik GK, Adkins RB Jr, Cherrington AD: Role of hepatic nerves in response of liver to intraportal glucose delivery in dogs. Am J Physiol 262:E679-E686, 1992
27. Frayn KN: Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 55: 628-634, 1983
28. Lukaski HC, Johnson PE, Bolonchuk WW, Lykken GI: Assessment of fat-free mass using bioelectrical impedance measurements of the human body. Am J Clin Nutr 41:810-817, 1985
29. Bak JF, Pedersen O: Exercise-enhanced activation of glycogen synthase in human skeletal muscle. Am J Physiol 258:E957-E963, 1990
30. Easterby JS, Qadri SS: Hexokinase type II from rat skeletal muscle. Methods Enzymol 90:11-15, 1977
31. Andersen L, Dinesen B, Jorgensen PN, Poulsen F, Røder ME: Enzyme immunoassay of intact insulin in serum and plasma. Clin Chem 39:578-582, 1993
32. Holst JJ: Evidence that glicentin contains the entire sequence of glucagon. Biochem J 187:337-343, 1980
33. Itaya K, Michio U: Colorimetric determination of free fatty acids in biological fluids. J Lipid Res 6:16-20, 1965
34. Passonneau JV: L-(+)-Lactate: fluorometric method. In Methods of Enzymatic Analysis. Vol. 3. Bergmeyer HV, Ed. New York, Academic, 1974, p. 1468-1472
35. Blackman JD, Polonsky KS, Jaspan JB, Sturis J, Cauter EV, Thistlethwaite RJ Jr: Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation. Diabetes 41:1346-1354, 1992
36. Osei K, Henry ML, O'Dorisio TM, Tesi RJ, Sommer BG, Ferguson RM: Physiological and pharmacological stimulation of pancreatic islet hormone secretion in type 1 diabetic pancreas allograft recipients. Diabetes 39:1235-1242, 1990
37. Katz H, Homan M, Velosa J, Robertson P, Rizza R: Effects of pancreas transplantation on postprandial glucose metabolism. N Engl J Med 325:1278-1283, 1991
38. Kahn C: Insulin resistance, insulin insensitivity, and insulin unresponsiveness: a necessary distinction. Metabolism 27:1893-1902, 1978
39. Pagano G, Cavallo-Perin P, Cassader B, Bruno A, Ozzello A, Masciola P: An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects. J Clin Invest 72:1814-1820, 1983
40. Myers SR, Diamond MP, Adkins-Marshall BA, Williams PE, Stinsen R, Cherrington AD: Effects of small changes in glucagon on glucose production during a euglycemic, hyperinsulinemic clamp. Metabolism 40:66-71, 1991
41. Rebrin K, Steil GM, Getty L, Bergman RN: Free fatty acids as a link in the regulation of hepatic glucose output by peripheral insulin. Diabetes 44:1038-1045, 1995
42. Kolterman OG, Insel LJ, Saekow M, Olefsky JM: Mechanisms of insulin resistance in human obesity: evidence for receptor and post-receptor defects. J Clin Invest 65:1272-1280, 1980
43. Weinstein SP, Paquin T, Pritsker A, Haber RS: Glucocorticoid-induced insulin resistance: dexamethasone inhibits activation of glucose transport in rat skeletal muscle by both insulin- and non-insulin-related stimuli. Diabetes 44:441-445, 1995
44. Radziuk J, Barron P, Najm H, Davies J: The effect of systemic venous drainage of the pancreas on insulin sensitivity in dogs. J Clin Invest 92:1713-1721, 1993
45. Del Prato S, Leonetti F, Simonson DC, Sheehan P, Matsuda M, DeFronzo RA: Effect of sustained physiologic hyperinsulinemia and hyperglycemia on insulin secretion and insulin sensitivity in man. Diabetologia 37:1025-1035, 1994
46. Bar R, Gordon P, Roth J, Kahn C, DeMyets P: Fluctuations in the affinity and concentrations of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding and dieting. J Clin Invest 58:1123-1135, 1976
47. Ward GM, Weber KM, Walters IM, Aitken PM, Lee B, Best JD, Boston RC, Alford FP: A modified minimal model analysis of insulin sensitivity and glucose-mediated glucose disposal in insulin dependent diabetes. Metabolism 40:4-9, 1991
48. Welch S, Gebhart SSP, Bergman RN, Phillips LS: Minimal model analysis of intravenous tolerance test-derived insulin sensitivity in diabetic subjects. J Clin Endocrinol Metab 71:1508-1518, 1990
49. Randle PJ, Hales CN, Garland PB, Newsholme EA: The glucose-fatty acid circle: its role in insulin sensitivity and the metabolic disturbances in diabetes mellitus. Lancet i:785-789, 1963
50. Boden G, Chen X, Ruiz J, Heifets M, Morris M, Badosa F: Insulin receptor down-regulation and impaired antilipolytic action of insulin in diabetic patients after pancreas/kidney transplantation. J Clin Endocrinol Metab 78:657-663, 1994
51. DeFronzo RA, Bonadonna R, Ferrannini E: Pathogenesis of NIDDM: a balanced overview. Diabetes Care 15:318-368, 1992
52. Cohen P: Muscle glycogen synthase. In The Enzymes. Boyer PD, Krebs EG, Eds. New York, Harcourt Brace Jovanovich, 1986, p. 461-497