Design, synthesis, and in vitro evaluation of cyclic nitrones as free radical traps for the treatment of stroke

Journal of Medicinal Chemistry

Volumn 39, Issue 25, 1996, Pages 4988-4996

  Fevig, Thomas L ^a   Bowen, S Marc ^a   Janowick, David A ^a,b   Jones, Bryan K ^a   Munson, H Randall ^a   Ohlweiler, David F ^a   Thomas, Craig E ^a,c  

^a SANOFI   (France)

^b ABBOTT LABORATORIES   (United States)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,3 DIMETHYL 3,4 DIHYDROISOQUINOLINE N OXIDE; 3,3,5,7 TETRAMETHYL 3,4 DIHYDROISOQUINOLIN 6 OL; ANTIOXIDANT; FREE RADICAL; N TERT BUTYL ALPHA PHENYLNITRONE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CONJUGATION; CONTROLLED STUDY; DRUG DESIGN; DRUG DETERMINATION; DRUG POTENCY; DRUG SYNTHESIS; LIPID PEROXIDATION; LIPOPHILICITY; OXIDATIVE STRESS; STROKE; X RAY CRYSTALLOGRAPHY;

CEREBROVASCULAR DISORDERS; LIPID PEROXIDATION; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; NITROGEN OXIDES;

EID: 0029731583     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960243v     Document Type: Article

References (40)

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