Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p

Molecular Biology of the Cell

Volumn 14, Issue 4, 2003, Pages 1610-1623

  Conibear, Elizabeth ^a,b   Cleck, Jessica N ^a,c   Stevens, Tom H ^a  

^a UNIVERSITY OF OREGON   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROTEIN SUBUNIT; PROTEIN VPS51P; PROTEIN VPS52; PROTEIN VPS53; PROTEIN VPS54; SNARE PROTEIN; T SNARE TLG1P; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; ENDOSOME; GOLGI COMPLEX; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEIN TRANSPORT;

BIOLOGICAL TRANSPORT, ACTIVE; CARRIER PROTEINS; CLONING, MOLECULAR; ENDOSOMES; GOLGI APPARATUS; MACROMOLECULAR SUBSTANCES; MEMBRANE FUSION; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MUTATION; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SNARE PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES; VESICULAR TRANSPORT PROTEINS;

EID: 0013468039     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-10-0654     Document Type: Article

References (32)

1. Antonin, W., Dulubova, I., Arac, D., Pabst, S., Plitzner, J., Rizo, J., and Jahn, R. (2002). The N-terminal domains of syntaxin 7 and vtilb form three-helix bundles that differ in their ability to regulate SNARE complex assembly. J. Biol. Chem. 11, 11.
2. Bonangelino, C.J., Chavez, E.M., and Bonifacino, J.S. (2002). Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol. Biol. Cell 13, 2486-2501.
3. Chen, Y.A., and Scheller, R.H. (2001). SNARE-mediated membrane fusion. Nat. Rev. Mol. Cell Biol. 2, 98-106.
4. Conibear, E., and Stevens, T.H. (1998). Multiple sorting pathways between the late Golgi and the vacuole in yeast. Biochim. Biophys. Acta. 1404, 211-230.
5. Conibear, E., and Stevens, T.H. (2000). Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi. Mol. Biol. Cell 11, 305-323.
6. Conibear, E., and Stevens, T.H. (2002). Studying yeast vacuoles. Methods Enzymol. 351,408-432.
7. Dulubova, I., Sugita, S., Hill, S., Hosaka, M., Fernandez, I., Sudhof, T.C., and Rizo, J. (1999). A conformational switch in syntaxin during exocytosis: role of munc18. EMBO J. 18, 4372-4382.
8. Dulubova, I., Yamaguchi, T., Gao, Y., Min, S.W., Huryeva, I., Sudhof, T.C., and Rizo, J. (2002). How Tlg2p/syntaxin 16 'snares' Vps45 Vp s45. EMBO J. 21, 3620-3631.
9. Dulubova, I., Yamaguchi, T., Wang, Y., Sudhof, T.C., and Rizo, J. (2001). Vam3p structure reveals conserved and divergent properties of syntaxins. Nat. Struct. Biol. 8, 258-264.
10. Fernandez, I., Ubach, J., Dulubova, I., Zhang, X., Sudhof, T.C., and Rizo, J. (1998). Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A. Cell 94, 841-849.
11. Guo, W., Roth, D., Walch-Solimena, C., and Novick, P. (1999). The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis. EMBO J. 18, 1071-1080.
12. Holthuis, J.C., Nichols, B.J., Dhruvakumar, S., and Pelham, H.R. (1998). Two syntaxin homologues in the TGN/endosomal system of yeast. EMBO J. 17, 113-126.
13. James, P., Halladay, J., and Craig, E.A. (1996). Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144, 1425-1436.
14. Lewis, M.J., Nichols, B.J., Prescianotto-Baschong, C., Riezman, H., and Pelham, H.R. (2000). Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes. Mol. Biol. Cell 11, 23-38.
15. Longtine, M.S., McKenzie, A., 3rd, Demarini, D.J., Shah, N.G., Wach, A., Brachat, A., Philippsen, P., and Pringle, J.R. (1998). Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14, 953-961.
16. Misura, K.M., Bock, J.B., Gonzalez, L.C., Jr., Scheller, R.H., and Weis, W.I. (2002). Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog. Proc. Natl. Acad. Sci. USA 99, 9184-9189.
17. Morsomme, P., and Riezman, H. (2002). The Rab GTPase Ypt1p and tethering factors couple protein sorting at the ER to vesicle targeting to the Golgi apparatus. Dev. Cell 2, 307-317.
18. Nichols, B.J., Holthuis, J.C., and Pelham, H.R. (1998). The Sec1p homologue Vps45p binds to the syntaxin Tlg2p. Eur J. Cell Biol. 77, 263-268.
19. Panek, H.R., Conibear, E., Bryan, J.D., Colvin, R.T., Goshorn, C.D., and Robinson, L.C. (2000). Identification of Rgp1p, a novel Golgi recycling factor, as a protein required for efficient localization of yeast casein kinase 1 to the plasma membrane. J. Cell Sci. 113, 4545-4555.
20. Parlati, F., Weber, T., McNew, J.A., Westermann, B., Sollner, T.H., and Rothman, J.E. (1999). Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain. Proc. Natl. Acad. Sci. USA 96, 12565-12570.
21. Paumet, F., Brugger, B., Parlati, F., McNew, J.A., Sollner, T.H., and Rothman, J.E. (2001). A t-SNARE of the endocytic pathway must be activated for fusion. J. Cell Biol. 155, 961-968.
22. Peng, R., and Gallwitz, D. (2002). Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes. J. Cell Biol. 157, 645-655.
23. Siniossoglou, S., Peak-Chew, S.Y., and Pelham, H.R. (2000). Ric1p and Rgp1p form a complex that catalyzes nucleotide exchange on Ypt6p. EMBO J. 19, 4885-4894.
24. Siniossoglou, S., and Pelham, H.R. (2001). An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes. EMBO J. 20, 5991-5998.
25. Siniossoglou, S., and Pelham, H.R. (2002). Vps51p links the VFT complex to the SNARE Tlg1p. J. Biol. Chem. 277, 48318-48324.
26. Suvorova, E.S., Duden, R., and Lupashin, V.V. (2002). The Sec34/Sec35p complex, a Ypt1p effector required for retrograde intra-Golgi trafficking, interacts with Golgi SNAREs and COPI vesicle coat proteins. J. Cell Biol. 157, 631-643.
27. Tochio, H., Tsui, M.M., Banfield, D.K., and Zhang, M. (2001). An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p. Science 293, 698-702.
28. Ungar, D., Oka, T., Brittle, E.E., Vasile, E., Lupashin, V.V., Chatterton, J.E., Heuser, J.E., Krieger, M., and Waters, M.G. (2002). Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function. J. Cell Biol. 157, 405-415.
29. Whyte, J.R., and Munro, S. (2001). The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic. Dev. Cell 1, 527-537.
30. Whyte, J.R., and Munro, S. (2002). Vesicle tethering complexes in membrane traffic. J. Cell Sci. 115, 2627-2637.
31. Yamaguchi, T., Dulubova, I., Min, S.W., Chen, X., Rizo, J., and Sudhof, T.C. (2002). Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif. Dev. Cell 2, 295-305.
32. Yeaman, C., Grindstaff, K.K., Wright, J.R., and Nelson, W.J. (2001). Sec6/8 complexes on trans-Golgi network and plasma membrane regulate late stages of exocytosis in mammalian cells. J. Cell Biol. 155, 593-604.