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Volumn 1, Issue 3, 2002, Pages 179-187

Hypercalcemia of malignancy: Pathophysiology diagnosis and treatment

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CALCITONIN; CALCIUM; CLODRONIC ACID; CYTOKINE; ESTROGEN; IBANDRONIC ACID; INTERLEUKIN 1; INTERLEUKIN 6; MITHRAMYCIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY PTHRP; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PAMIDRONIC ACID; PARATHYROID HORMONE RELATED PROTEIN; PROSTAGLANDIN DERIVATIVE; SEOCALCITOL; TAMOXIFEN; THIAZIDE DIURETIC AGENT; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VITAMIN D; ZOLEDRONIC ACID;

EID: 0013358905     PISSN: 11756357     EISSN: None     Source Type: Journal    
DOI: 10.2165/00024669-200201030-00003     Document Type: Review
Times cited : (4)

References (94)
  • 1
    • 0025908905 scopus 로고
    • Hypercalcemia of malignancy: Pathophysiology, diagnosis and treatment
    • Mosekilde L, Eriksen EF, Charles P. Hypercalcemia of malignancy: pathophysiology, diagnosis and treatment. Crit Rev Oncol Hematol 1991; 11: 1-27
    • (1991) Crit Rev Oncol Hematol , vol.11 , pp. 1-27
    • Mosekilde, L.1    Eriksen, E.F.2    Charles, P.3
  • 2
    • 0019158232 scopus 로고
    • Hypercalcemia: A hospital survey
    • Fisken RA, Heath DA, Bold AM. Hypercalcemia: a hospital survey. Q J Med 1980; 49: 405-18
    • (1980) Q J Med , vol.49 , pp. 405-418
    • Fisken, R.A.1    Heath, D.A.2    Bold, A.M.3
  • 3
    • 0019461537 scopus 로고
    • Hypercalcemia in hospital patients: Clinical and diagnostic aspects
    • Fisken RA. Heath DA, Sommers S, et al. Hypercalcemia in hospital patients: clinical and diagnostic aspects. Lancet 1981; I: 202-7
    • (1981) Lancet , vol.1 , pp. 202-207
    • Fisken, R.A.1    Heath, D.A.2    Sommers, S.3
  • 4
    • 0020419637 scopus 로고
    • The hypercalcemia of malignancy: Pathogenesis and management
    • Mundy GR, Martin TJ. The hypercalcemia of malignancy: pathogenesis and management. Metabolism 1982; 31: 1247-77
    • (1982) Metabolism , vol.31 , pp. 1247-1277
    • Mundy, G.R.1    Martin, T.J.2
  • 5
    • 0022835913 scopus 로고
    • Malignant hypercalcemia: A hospital survey
    • Blomqvist CP. Malignant hypercalcemia: a hospital survey. Acta Med Scand 1986; 220: 455-63
    • (1986) Acta Med Scand , vol.220 , pp. 455-463
    • Blomqvist, C.P.1
  • 6
    • 0031043490 scopus 로고    scopus 로고
    • Population-based health screening for primary hyperparathyroidism with serum calcium and parathyroid hormone values in menopausal women
    • Lundgren E. Population-based health screening for primary hyperparathyroidism with serum calcium and parathyroid hormone values in menopausal women. Surgery 1997; 121: 287-94
    • (1997) Surgery , vol.121 , pp. 287-294
    • Lundgren, E.1
  • 9
    • 0027765508 scopus 로고
    • Cloning and characterization of an extracellular Ca2+ sensing receptor from bovine parathyroid
    • Brown E, Gamba G, Riccardi D, et al. Cloning and characterization of an extracellular Ca2+ sensing receptor from bovine parathyroid. Nature 1993; 366: 575-80
    • (1993) Nature , vol.366 , pp. 575-580
    • Brown, E.1    Gamba, G.2    Riccardi, D.3
  • 10
    • 0029055771 scopus 로고
    • Molecular cloning and functional expression of human parathyroid calcium receptor cDNA
    • Garrett JE, Capuano IV, Hammerland LG, et al. Molecular cloning and functional expression of human parathyroid calcium receptor cDNA. J Biol Chem 1995; 270: 12919-25
    • (1995) J Biol Chem , vol.270 , pp. 12919-12925
    • Garrett, J.E.1    Capuano, I.V.2    Hammerland, L.G.3
  • 11
    • 0029150178 scopus 로고
    • Molecular cloning of a putative calcium serum of senses receptor cDNA from human kidney
    • Aida K, Koishi S, Tawata M, et al. Molecular cloning of a putative calcium serum of senses receptor cDNA from human kidney. Biochem Biophys Res Commun 1995; 214: 524-9
    • (1995) Biochem Biophys Res Commun , vol.214 , pp. 524-529
    • Aida, K.1    Koishi, S.2    Tawata, M.3
  • 12
    • 0028955536 scopus 로고
    • Calcium sensing receptor: Molecular cloning in rat and localization to nerve terminals
    • Ruat M, Molliver ME, Snowman A, et al. Calcium sensing receptor: molecular cloning in rat and localization to nerve terminals. Proc Natl Acad Sci USA 1995; 92: 3161-5
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3161-3165
    • Ruat, M.1    Molliver, M.E.2    Snowman, A.3
  • 13
    • 0028924833 scopus 로고
    • Cloning and function expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor
    • Riccardi D, Park JI, Lee WS, et al. Cloning and function expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor. Proc Natl Acad Sci USA 1995; 92: 131-5
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 131-135
    • Riccardi, D.1    Park, J.I.2    Lee, W.S.3
  • 14
    • 0028792434 scopus 로고
    • Calcitonin-secreting cells of the thyroid express an extracellular calcium receptor gene
    • Garrett JE, Tamir H, Kifor O, et al. Calcitonin-secreting cells of the thyroid express an extracellular calcium receptor gene. Endocrinology 1995; 136 (11): 5202-11
    • (1995) Endocrinology , vol.136 , Issue.11 , pp. 5202-5211
    • Garrett, J.E.1    Tamir, H.2    Kifor, O.3
  • 15
    • 0027787680 scopus 로고
    • Mutations in the human Ca2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism
    • Pollak MR, Brown EM, Chou YMH, et al. Mutations in the human Ca2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell 1993; 75: 1297-303
    • (1993) Cell , vol.75 , pp. 1297-1303
    • Pollak, M.R.1    Brown, E.M.2    Chou, Y.M.H.3
  • 16
    • 0033800097 scopus 로고    scopus 로고
    • Mutations of the calcium-sensing receptor (CASR) in familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism and autosomal dominant hypocalcemia
    • Hendy GN, D'Sousa-Li L, Yang B, et al. Mutations of the calcium-sensing receptor (CASR) in familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism and autosomal dominant hypocalcemia. Hum Mutat 2000; 16: 281-96
    • (2000) Hum Mutat , vol.16 , pp. 281-296
    • Hendy, G.N.1    D'Sousa-Li, L.2    Yang, B.3
  • 17
    • 0035138842 scopus 로고    scopus 로고
    • Extra cellular calcium sensing and extracellular calcium signaling
    • Brown EM, Macleod RJ. Extra cellular calcium sensing and extracellular calcium signaling. Physiol Rev 2001; 81: 239-97
    • (2001) Physiol Rev , vol.81 , pp. 239-297
    • Brown, E.M.1    Macleod, R.J.2
  • 18
    • 0035286349 scopus 로고    scopus 로고
    • Molecular pathology of parathyroid tumours
    • Carling T. Molecular pathology of parathyroid tumours. Trends Endocrinol Metab 2001; 12: 53-8
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 53-58
    • Carling, T.1
  • 19
    • 0032213013 scopus 로고    scopus 로고
    • Ca2+ receptor from brain to gut: Common stimulus, diverse actions
    • Chattopakhyay N, Yamaguchi T, Brown E. Ca2+ receptor from brain to gut: common stimulus, diverse actions. Trends Endocrinal Metab 1998; 9 (9): 354-9
    • (1998) Trends Endocrinal Metab , vol.9 , Issue.9 , pp. 354-359
    • Chattopakhyay, N.1    Yamaguchi, T.2    Brown, E.3
  • 20
    • 0019123019 scopus 로고
    • Biochemical evaluation of patients with cancer-associated hypercalcemia: Evidence for humoral and nonhumoral groups
    • Stewart AF, Horst R, Deftos LJ, et al. Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups. N Engl J Med 1980; 303 (24): 1377-83
    • (1980) N Engl J Med , vol.303 , Issue.24 , pp. 1377-1383
    • Stewart, A.F.1    Horst, R.2    Deftos, L.J.3
  • 21
    • 0000840985 scopus 로고
    • Case records of the Massachusetts General Hospital (case 27401)
    • Albright F. Case records of the Massachusetts General Hospital (case 27401). N Engl J Med 1941; 225: 789-91
    • (1941) N Engl J Med , vol.225 , pp. 789-791
    • Albright, F.1
  • 22
    • 0345338496 scopus 로고
    • Parathyroid hormone-related protein purified from a human lung cancer cell line
    • Moseley JM, Kubota M, Diefenback-Jagger H, et al. Parathyroid hormone-related protein purified from a human lung cancer cell line. Proc Natl Acad Sci USA 1987; 84: 5048-52
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5048-5052
    • Moseley, J.M.1    Kubota, M.2    Diefenback-Jagger, H.3
  • 23
    • 0023259132 scopus 로고
    • Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumour associated with humoral hypercalcemia of malignancy
    • Burtis WJ, Wu T, Bunch C, et al. Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumour associated with humoral hypercalcemia of malignancy. J Biol Chem 1987; 262 (15): 7151-6
    • (1987) J Biol Chem , vol.262 , Issue.15 , pp. 7151-7156
    • Burtis, W.J.1    Wu, T.2    Bunch, C.3
  • 24
    • 0023472542 scopus 로고
    • Parathyroid hormone-like protein from human renal carcinoma cells structural and function homology with parathyroid hormone
    • Strewler GJ, Stern P, Jacobs J, et al. Parathyroid hormone-like protein from human renal carcinoma cells structural and function homology with parathyroid hormone. J Clin Invest 1987; 80: 1803-7
    • (1987) J Clin Invest , vol.80 , pp. 1803-1807
    • Strewler, G.J.1    Stern, P.2    Jacobs, J.3
  • 25
    • 0023228836 scopus 로고
    • A parathyroid hormone-related protein implicated in malignant hypercalcemia: Cloning and expression
    • Suva LJ, Winslow GA, Wettenhall REH, et al. A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression. Science 1987; 237: 893-6
    • (1987) Science , vol.237 , pp. 893-896
    • Suva, L.J.1    Winslow, G.A.2    Wettenhall, R.E.H.3
  • 26
    • 0026598246 scopus 로고
    • Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: A single receptor stimulated intracellular accumulation of both cAMP and inositol triphosphate and increases intracellular free calcium
    • Abou-Samra A, Juppner H, Force T, et al. Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulated intracellular accumulation of both cAMP and inositol triphosphate and increases intracellular free calcium. Proc Natl Acad Sci USA 1992; 89: 2732-6
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2732-2736
    • Abou-Samra, A.1    Juppner, H.2    Force, T.3
  • 27
    • 0023631458 scopus 로고
    • Similarity of synthetic peptide from human tumour to parathyroid hormone in vivo and in vitro
    • Horluchi N, Caulfield M, Fisher JE, et al. Similarity of synthetic peptide from human tumour to parathyroid hormone in vivo and in vitro. Science 1987; 238: 1566-8
    • (1987) Science , vol.238 , pp. 1566-1568
    • Horluchi, N.1    Caulfield, M.2    Fisher, J.E.3
  • 28
    • 0023626201 scopus 로고
    • Parathyroid hormone-related protein of malignancy: Active synthetic fragments
    • Kemp BE, Moseley JM, Rodda CP, et al. Parathyroid hormone-related protein of malignancy: active synthetic fragments. Science 1987; 238: 1568-70
    • (1987) Science , vol.238 , pp. 1568-1570
    • Kemp, B.E.1    Moseley, J.M.2    Rodda, C.P.3
  • 29
    • 0025318826 scopus 로고
    • Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer
    • Burtis WJ, Bady TF, Orloff JJ, et al. Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. N Engl J Med 1990: 322: 1106-12
    • (1990) N Engl J Med , vol.322 , pp. 1106-1112
    • Burtis, W.J.1    Bady, T.F.2    Orloff, J.J.3
  • 31
    • 0002415989 scopus 로고
    • Parathyroid hormone-related protein: Structure, processing, and physiological actions
    • Bilezikian JP, Levine M, Marcus R, editors. New York: Raven Press
    • Broadus A, Stewart A, Bilezikian JP, et al. Parathyroid hormone-related protein: structure, processing, and physiological actions. In: Bilezikian JP, Levine M, Marcus R, editors. The parathyroids. New York: Raven Press, 1994: 259
    • (1994) The Parathyroids , pp. 259
    • Broadus, A.1    Stewart, A.2    Bilezikian, J.P.3
  • 33
    • 0025674602 scopus 로고
    • Immunohistochemical localization of parathyroid hormone-related protein in breast cancer
    • Southby J, Kissin MW, Danks JA, et al. Immunohistochemical localization of parathyroid hormone-related protein in breast cancer. Cancer Res 1990; 50: 7710-6
    • (1990) Cancer Res , vol.50 , pp. 7710-7716
    • Southby, J.1    Kissin, M.W.2    Danks, J.A.3
  • 34
    • 10144241022 scopus 로고    scopus 로고
    • Evidence for a causal role of parathyroid hormone-related protein in breast cancer-mediated osteolysis
    • Guise TA, Yin JJ, Taylor SD, et al. Evidence for a causal role of parathyroid hormone-related protein in breast cancer-mediated osteolysis. J Clin Invest 1996; 98 (7): 1544-8
    • (1996) J Clin Invest , vol.98 , Issue.7 , pp. 1544-1548
    • Guise, T.A.1    Yin, J.J.2    Taylor, S.D.3
  • 35
    • 0033305222 scopus 로고    scopus 로고
    • Breast cancer cells interact with osteoblasts to support osteoclast formation
    • Thomas RJ, Guise TA, Yin JJ, et al. Breast cancer cells interact with osteoblasts to support osteoclast formation. Endocrinology 1999; 140: 4451-8
    • (1999) Endocrinology , vol.140 , pp. 4451-4458
    • Thomas, R.J.1    Guise, T.A.2    Yin, J.J.3
  • 36
    • 0027410965 scopus 로고
    • Transforming growth factor β stimulation of parathyroid hormone-related protein (PTHrP): A paracrine regulator?
    • Kiriyama T, Gillespie MT, Glatz JA, et al. Transforming growth factor β stimulation of parathyroid hormone-related protein (PTHrP): a paracrine regulator? Mol Cell Endocrinol 1992; 92: 55-62
    • (1992) Mol Cell Endocrinol , vol.92 , pp. 55-62
    • Kiriyama, T.1    Gillespie, M.T.2    Glatz, J.A.3
  • 37
    • 0028355732 scopus 로고
    • Effects oftransforming growth factor-β on parathyroid hormone-related protein production and ribonucleic acid expression by a squamous carcinoma cell line in vitro
    • Merryman JI, DeWille JW, Werkmeister JR, et al. Effects oftransforming growth factor-β on parathyroid hormone-related protein production and ribonucleic acid expression by a squamous carcinoma cell line in vitro. Endocrinology 1994; 134: 2424-30
    • (1994) Endocrinology , vol.134 , pp. 2424-2430
    • Merryman, J.I.1    DeWille, J.W.2    Werkmeister, J.R.3
  • 38
    • 0017137603 scopus 로고
    • Mechanisms of bone destruction in the development of skeletal metastasis
    • Galasko CSB. Mechanisms of bone destruction in the development of skeletal metastasis. Nature 1976; 263: 507-8
    • (1976) Nature , vol.263 , pp. 507-508
    • Galasko, C.S.B.1
  • 39
    • 0018120428 scopus 로고
    • Direct resorption of bone by human breast cancer cells in vitro
    • Eilon G, Mundy GR. Direct resorption of bone by human breast cancer cells in vitro. Nature 1978; 276: 726-8
    • (1978) Nature , vol.276 , pp. 726-728
    • Eilon, G.1    Mundy, G.R.2
  • 40
    • 0030747949 scopus 로고    scopus 로고
    • Direct osteolysis induced by metastatic murine melanoma cells: Role of matrix metalloproteinases
    • Sanchez-Sweatman OH, Lee J, Orr FW, et al. Direct osteolysis induced by metastatic murine melanoma cells: role of matrix metalloproteinases. Eur J Cancer 1997; 33: 918-25
    • (1997) Eur J Cancer , vol.33 , pp. 918-925
    • Sanchez-Sweatman, O.H.1    Lee, J.2    Orr, F.W.3
  • 41
    • 0024419152 scopus 로고
    • Production of cytokines by bone marrow cells obtained from patients with multiple myeloma
    • Lichtenstein A, Berenson J, Norman D, et al. Production of cytokines by bone marrow cells obtained from patients with multiple myeloma. Blood 1989; 74: 1266-73
    • (1989) Blood , vol.74 , pp. 1266-1273
    • Lichtenstein, A.1    Berenson, J.2    Norman, D.3
  • 42
    • 0025098172 scopus 로고
    • Effect of glucocorticoids on the biologic activities of myeloma cells: Inhibition of interleukin-1 beta osteoclasts factor-induced bone resorption
    • Ishikawa H, Tanaka H, Iwato K, et al. Effect of glucocorticoids on the biologic activities of myeloma cells: inhibition of interleukin-1 beta osteoclasts factor-induced bone resorption. Blood 1990; 75: 715-20
    • (1990) Blood , vol.75 , pp. 715-720
    • Ishikawa, H.1    Tanaka, H.2    Iwato, K.3
  • 43
    • 0026357819 scopus 로고
    • Interleukin-6 messenger RNA expression and interleukin-6 protein secretion in cells isolated from normal human bone: Regulation by interleukin-1
    • Linkhart TA, Linkhart SG, MacCharles DC, et al. Interleukin-6 messenger RNA expression and interleukin-6 protein secretion in cells isolated from normal human bone: regulation by interleukin-1. J Bone Miner Res 1991; 6: 1285-94
    • (1991) J Bone Miner Res , vol.6 , pp. 1285-1294
    • Linkhart, T.A.1    Linkhart, S.G.2    MacCharles, D.C.3
  • 44
    • 0031862959 scopus 로고    scopus 로고
    • Severe hypercalcemia and extensive osteolytic lesions in an adult patient with T cell acute lymphoblastic leukemia
    • Antunovic P, Marisavljevic D, Kraguljac N, et al. Severe hypercalcemia and extensive osteolytic lesions in an adult patient with T cell acute lymphoblastic leukemia. Med Oncol 1998; 15: 58-60
    • (1998) Med Oncol , vol.15 , pp. 58-60
    • Antunovic, P.1    Marisavljevic, D.2    Kraguljac, N.3
  • 45
    • 0023508049 scopus 로고
    • Hypercalcaemia in a case of childhood acute lymphoblastic leukemia
    • Todo S, Imashuku S, Inoda H, et al. Hypercalcaemia in a case of childhood acute lymphoblastic leukemia. Jpn J Clin Oncol 1987; 17: 357-62
    • (1987) Jpn J Clin Oncol , vol.17 , pp. 357-362
    • Todo, S.1    Imashuku, S.2    Inoda, H.3
  • 46
    • 0022971650 scopus 로고
    • Hypercalcemia in T cell acute lymphoblastic leukemia: Report of two cases
    • Laffan MA, Talavera JG, Catovsky D. Hypercalcemia in T cell acute lymphoblastic leukemia: report of two cases. J Clin Pathol 1986; 39: 1143-6
    • (1986) J Clin Pathol , vol.39 , pp. 1143-1146
    • Laffan, M.A.1    Talavera, J.G.2    Catovsky, D.3
  • 47
    • 0034596062 scopus 로고    scopus 로고
    • Factor H binding to bone sialoprotein and osteopontin enables tumor cell invasion of complement-mediated attack
    • Fedarko NS, Fohr B, Robey PG, et al. Factor H binding to bone sialoprotein and osteopontin enables tumor cell invasion of complement-mediated attack. J Biol Chem 2000; 275: 16666-72
    • (2000) J Biol Chem , vol.275 , pp. 16666-16672
    • Fedarko, N.S.1    Fohr, B.2    Robey, P.G.3
  • 48
    • 0030976755 scopus 로고    scopus 로고
    • Cytokines expressed in multinucleated cells: Paget's disease and giant cell tumors versus normal bone
    • Mills BG, Frausto A. Cytokines expressed in multinucleated cells: Paget's disease and giant cell tumors versus normal bone. Calcif Tissue Int 1997; 61: 16-21
    • (1997) Calcif Tissue Int , vol.61 , pp. 16-21
    • Mills, B.G.1    Frausto, A.2
  • 49
    • 0035863508 scopus 로고    scopus 로고
    • Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: A pooled analysis of two randomized, controlled clinical trials
    • Major P, Lotholary A, Hon J, et al. Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials. J Clin Oncol 2001; 19: 558-67
    • (2001) J Clin Oncol , vol.19 , pp. 558-567
    • Major, P.1    Lotholary, A.2    Hon, J.3
  • 50
    • 0038390278 scopus 로고    scopus 로고
    • Immunohistochemical localization of matrix metalloproteinases in cancer metastatic to bone
    • The Second North American Symposium on Skeletal Complications of Malignancy; 1999 Oct 15-16; Montreal (PQ)
    • Frauenhoffer EE, Lipton A, Costa L, et al. Immunohistochemical localization of matrix metalloproteinases in cancer metastatic to bone. In: The Second North American Symposium on Skeletal Complications of Malignancy; 1999 Oct 15-16; Montreal (PQ). Cancer 2000; 88 (12 Suppl. 512): 3090
    • (2000) Cancer , vol.88 , Issue.12 SUPPL. 512 , pp. 3090
    • Frauenhoffer, E.E.1    Lipton, A.2    Costa, L.3
  • 51
    • 0038728482 scopus 로고    scopus 로고
    • Osteoclasts and tumour cells exhibit a different morphology of bone resorption pits and distinct MMP profiles in bone metastasis of human breast carcinoma
    • The Second North American Symposium on Skeletal Complications of Malignancy; 1999 Oct 15-16; Montreal (PQ)
    • Lhotak S, Elevathil LJ, Duivenvoorden WCM, et al. Osteoclasts and tumour cells exhibit a different morphology of bone resorption pits and distinct MMP profiles in bone metastasis of human breast carcinoma. In: The Second North American Symposium on Skeletal Complications of Malignancy; 1999 Oct 15-16; Montreal (PQ). Cancer 2000; 88 (12 Suppl. 512): 3091
    • (2000) Cancer , vol.88 , Issue.12 SUPPL. 512 , pp. 3091
    • Lhotak, S.1    Elevathil, L.J.2    Duivenvoorden, W.C.M.3
  • 52
    • 0022552717 scopus 로고
    • Resorbing bone stimulates tumour cell growth: A role for the host microenvironment in bone metastasis
    • Manishen WJ, Sivananthan K, Orr FW. Resorbing bone stimulates tumour cell growth: a role for the host microenvironment in bone metastasis. Am J Pathol 1986; 123: 39-45
    • (1986) Am J Pathol , vol.123 , pp. 39-45
    • Manishen, W.J.1    Sivananthan, K.2    Orr, F.W.3
  • 54
    • 1542792345 scopus 로고
    • Modulation of transforming growth factor β activity in bone cultures by osteotropic hormones
    • Pfeilschifter J, Mundy GR. Modulation of transforming growth factor β activity in bone cultures by osteotropic hormones. Proc Natl Acad Sci USA 1987; 84: 2024-8
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2024-2028
    • Pfeilschifter, J.1    Mundy, G.R.2
  • 55
    • 0034658725 scopus 로고    scopus 로고
    • Molecular mechanisms of osteolytic bone metastases in skeletal complications of malignancy
    • Guise TA. Molecular mechanisms of osteolytic bone metastases in skeletal complications of malignancy. Cancer 2000; 88 (12 Suppl.): 2892-8
    • (2000) Cancer , vol.88 , Issue.12 SUPPL. , pp. 2892-2898
    • Guise, T.A.1
  • 56
    • 0025317388 scopus 로고
    • Cancer-associated hypercalcemia: Morbidity and mortality, clinical experience in 126 treated patients
    • Ralston S, Gallacher S, Patel U, et al. Cancer-associated hypercalcemia: morbidity and mortality, clinical experience in 126 treated patients. Ann Intern Med 1990; 112: 499-504
    • (1990) Ann Intern Med , vol.112 , pp. 499-504
    • Ralston, S.1    Gallacher, S.2    Patel, U.3
  • 57
    • 0027533879 scopus 로고
    • Hypercalcémies néoplastiques: Facteurs prognostiques pour la survie des patients; à partir de 51 cas observés en médecine interne
    • Juchet H, Ollier S, Micouleau X, et al. Hypercalcémies néoplastiques: facteurs prognostiques pour la survie des patients; à partir de 51 cas observés en médecine interne. Rev Med Interne 1993; 14: 149-54
    • (1993) Rev Med Interne , vol.14 , pp. 149-154
    • Juchet, H.1    Ollier, S.2    Micouleau, X.3
  • 58
    • 0034659772 scopus 로고    scopus 로고
    • Parathyroid hormone-related protein as a potential target of therapy for cancer-associated morbidity
    • Ogata E. Parathyroid hormone-related protein as a potential target of therapy for cancer-associated morbidity. Cancer 2000; 88: 2909-11
    • (2000) Cancer , vol.88 , pp. 2909-2911
    • Ogata, E.1
  • 59
    • 0035725554 scopus 로고    scopus 로고
    • Hypercalcemia of malignancy: An undiagnosed and undertreated disease
    • Lamy O, Jenzer P, Burckhardt P. Hypercalcemia of malignancy: an undiagnosed and undertreated disease. J Intern Med 2001: 250: 73-9
    • (2001) J Intern Med , vol.250 , pp. 73-79
    • Lamy, O.1    Jenzer, P.2    Burckhardt, P.3
  • 60
    • 0027314436 scopus 로고
    • Pathophysiology and management of severe hypercalcemia
    • Nussbaum SR. Pathophysiology and management of severe hypercalcemia. Endocrinal Metab Clin North Am 1993; 22: 343-62
    • (1993) Endocrinal Metab Clin North Am , vol.22 , pp. 343-362
    • Nussbaum, S.R.1
  • 61
    • 0024543856 scopus 로고
    • Ectopic production of parathyroid hormone by small lung cancer in a patient with hypercalcemia
    • Yoshimoto K, Yamasaki R, Sakai H, et al. Ectopic production of parathyroid hormone by small lung cancer in a patient with hypercalcemia. J Clin Endocrinol Metab 1989; 68: 976-81
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 976-981
    • Yoshimoto, K.1    Yamasaki, R.2    Sakai, H.3
  • 62
    • 0031014236 scopus 로고    scopus 로고
    • Evaluation of a new, rapid and automated immunochemiluminometric assay for the measurement of serum intact parathyroid hormone
    • Michelangeli VP, Heyma P, Colman PG, et al. Evaluation of a new. rapid and automated immunochemiluminometric assay for the measurement of serum intact parathyroid hormone [abstract no. 9022895]. Ann Clin Biochem 1997; 34 (Pt 1): 97-103
    • (1997) Ann Clin Biochem , vol.34 , Issue.PART 1 , pp. 97-103
    • Michelangeli, V.P.1    Heyma, P.2    Colman, P.G.3
  • 63
    • 0029006051 scopus 로고    scopus 로고
    • Analysis of survival following treatment of tumour-induced hypercalcemia with intravenous pamidronate (APD)
    • Ling PJ, Hern RPA, Hardy JR. Analysis of survival following treatment of tumour-induced hypercalcemia with intravenous pamidronate (APD). Br J Cancer 1998; 72: 206-9
    • (1998) Br J Cancer , vol.72 , pp. 206-209
    • Ling, P.J.1    Hern, R.P.A.2    Hardy, J.R.3
  • 64
    • 0031814482 scopus 로고    scopus 로고
    • Survival in breast cancer patients after the first episode of hypercalcemia
    • Kristensen B, Ejlertsen B, Mouridsen HT, et al. Survival in breast cancer patients after the first episode of hypercalcemia. J Intern Med 1998; 244: 189-98
    • (1998) J Intern Med , vol.244 , pp. 189-198
    • Kristensen, B.1    Ejlertsen, B.2    Mouridsen, H.T.3
  • 67
    • 0027129189 scopus 로고
    • Management of acute hypercalcemia
    • Bilezikian JP. Management of acute hypercalcemia. N Engl J Med 1992; 326: 1196-203
    • (1992) N Engl J Med , vol.326 , pp. 1196-1203
    • Bilezikian, J.P.1
  • 69
    • 0023613966 scopus 로고
    • Rationale for diphosphonate therapy in hypercalcemia of malignancy
    • Canfield RE. Rationale for diphosphonate therapy in hypercalcemia of malignancy. Am J Med 1987; 82 Suppl. 2A: 1-5
    • (1987) Am J Med , vol.82 , Issue.SUPPL. 2A , pp. 1-5
    • Canfield, R.E.1
  • 70
    • 0014684354 scopus 로고
    • Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorbtion in tissue culture and in vivo
    • Fleisch H, Russell RGG, Francis MD. Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorbtion in tissue culture and in vivo. Science 1969; 165: 1262-4
    • (1969) Science , vol.165 , pp. 1262-1264
    • Fleisch, H.1    Russell, R.G.G.2    Francis, M.D.3
  • 71
    • 0014902988 scopus 로고
    • The influence of pyrophosphate, condensed phosphates, phosphonates and other phosphate compounds on the dissolution of hydroxyapatite in vitro and on bone resorbtion induced by parathyroid hormone in tissue culture and in thyroparathyroidectomised rats
    • Russell RGG, Muhlbauer RC, Bisaz S, et al. The influence of pyrophosphate, condensed phosphates, phosphonates and other phosphate compounds on the dissolution of hydroxyapatite in vitro and on bone resorbtion induced by parathyroid hormone in tissue culture and in thyroparathyroidectomised rats. Calcif Tissue Res 1970; 6: 183-96
    • (1970) Calcif Tissue Res , vol.6 , pp. 183-196
    • Russell, R.G.G.1    Muhlbauer, R.C.2    Bisaz, S.3
  • 72
    • 0031705391 scopus 로고    scopus 로고
    • Bone metastases: A review of their pathogenesis
    • Hirte HW, Major PP, Singh G. Bone metastases: a review of their pathogenesis. Curr Oncol Rep 1998; 5; 114-8
    • (1998) Curr Oncol Rep , vol.5 , pp. 114-118
    • Hirte, H.W.1    Major, P.P.2    Singh, G.3
  • 73
    • 0034659773 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of action of bisphosphonates
    • Rogers MJ, Gordon S, Benford HL, et al. Cellular and molecular mechanisms of action of bisphosphonates. Cancer 2000; 88: 2961-78
    • (2000) Cancer , vol.88 , pp. 2961-2978
    • Rogers, M.J.1    Gordon, S.2    Benford, H.L.3
  • 74
    • 0020696938 scopus 로고
    • Renal failure associated with I intravenous diphophonates
    • Bounameaux HM, Schifferli J, Montani JP, et al. Renal failure associated with I intravenous diphophonates [letter]. Lancet 1983; (8322): 471
    • (1983) Lancet , vol.1 , Issue.8322 , pp. 471
    • Bounameaux, H.M.1    Schifferli, J.2    Montani, J.P.3
  • 75
    • 0032758687 scopus 로고    scopus 로고
    • Comparative tolerability of drug therapies for hypercalcaemia of malignancy
    • Zojer N, Keck AV, Pecherstorfer M. Comparative tolerability of drug therapies for hypercalcaemia of malignancy. Drug Saf 1999; 21: 389-406
    • (1999) Drug Saf , vol.21 , pp. 389-406
    • Zojer, N.1    Keck, A.V.2    Pecherstorfer, M.3
  • 76
    • 0027534523 scopus 로고
    • Effective treatment of malignant hypercalcemia with a single intravenous infusion of clodronate
    • O'Rourke NP, McCloskey EV, Vasikaran S, et al. Effective treatment of malignant hypercalcemia with a single intravenous infusion of clodronate. Br J Cancer 1993; 67: 560-3
    • (1993) Br J Cancer , vol.67 , pp. 560-563
    • O'Rourke, N.P.1    McCloskey, E.V.2    Vasikaran, S.3
  • 77
    • 0031032567 scopus 로고    scopus 로고
    • Evaluation of new bone resorbtion markers in a randomized comparison of pamidronate and clodronate for hypercalcemia of malignancy
    • Vinholes J, Guo CY, Purohit OP, et al. Evaluation of new bone resorbtion markers in a randomized comparison of pamidronate and clodronate for hypercalcemia of malignancy. J Clin Oncol 1997; 15 (1): 131-8
    • (1997) J Clin Oncol , vol.15 , Issue.1 , pp. 131-138
    • Vinholes, J.1    Guo, C.Y.2    Purohit, O.P.3
  • 78
    • 0026593561 scopus 로고
    • Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia
    • Gucalp R, Ritch P, Wiernik PH, et al. Comparative study of pamidronate disodium and etidronate disodium in the treatment of cancer-related hypercalcemia. J Clin Oncol 1992; 10: 134-42
    • (1992) J Clin Oncol , vol.10 , pp. 134-142
    • Gucalp, R.1    Ritch, P.2    Wiernik, P.H.3
  • 79
    • 0025270315 scopus 로고
    • Fast (4-h) or slow (24-h) infusions of pamidronate disodium (aminohydroxypropylidene diphosphonate [APD]) as single short treatment of hypercalcemia
    • Sawyer N, Newstead C, Drummond A, et al. Fast (4-h) or slow (24-h) infusions of pamidronate disodium (aminohydroxypropylidene diphosphonate [APD]) as single short treatment of hypercalcemia. Bone Miner 1990; 9: 121-8
    • (1990) Bone Miner , vol.9 , pp. 121-128
    • Sawyer, N.1    Newstead, C.2    Drummond, A.3
  • 80
    • 0028040828 scopus 로고
    • Treatment of cancer-associated hypercalcemia: Double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone
    • Gucalp R, Theriault R, Gill I, et al. Treatment of cancer-associated hypercalcemia: double-blind comparison of rapid and slow intravenous infusion regimens of pamidronate disodium and saline alone. Arch Intern Med 1994; 154: 1935-44
    • (1994) Arch Intern Med , vol.154 , pp. 1935-1944
    • Gucalp, R.1    Theriault, R.2    Gill, I.3
  • 81
    • 0027214135 scopus 로고
    • Single-dose intravenous therapy with pamidronate for the treatment of hypercalcemia of malignancy: Comparison of 30-, 60-, and 90-mg dosages
    • Nussbaum SR, Younger J, Vandepol CJ, et al. Single-dose intravenous therapy with pamidronate for the treatment of hypercalcemia of malignancy: comparison of 30-, 60-, and 90-mg dosages. Am J Med 1993; 95: 297-304
    • (1993) Am J Med , vol.95 , pp. 297-304
    • Nussbaum, S.R.1    Younger, J.2    Vandepol, C.J.3
  • 82
    • 0027220322 scopus 로고
    • Dose-response study of alendronate sodium for the treatment of cancer-associated hypercalcemia
    • Nussbaum SR, Warrell Jr RP, Rude R, et al. Dose-response study of alendronate sodium for the treatment of cancer-associated hypercalcemia. J Clin Oncol 1993; 11: 1618-23
    • (1993) J Clin Oncol , vol.11 , pp. 1618-1623
    • Nussbaum, S.R.1    Warrell R.P., Jr.2    Rude, R.3
  • 83
    • 8044222736 scopus 로고    scopus 로고
    • Dose-response study of ibandronate in the treatment of cancer-associated hypercalcemia
    • Ralston SH, Thieband D, Herrmann Z, et al. Dose-response study of ibandronate in the treatment of cancer-associated hypercalcemia. Br J Cancer 1997; 75: 295-300
    • (1997) Br J Cancer , vol.75 , pp. 295-300
    • Ralston, S.H.1    Thieband, D.2    Herrmann, Z.3
  • 85
    • 0038052016 scopus 로고    scopus 로고
    • Novel anti-angiogenic effects of the bisphosphonate compound zoledronic acid, a potent inhibitor of bone resorbtion
    • Mar 24-28; New Orleans (LA)
    • Wood JM, Bonjean K, Ruetz S, et al. Novel anti-angiogenic effects of the bisphosphonate compound zoledronic acid, a potent inhibitor of bone resorbtion [abstract no. 3166]. 92nd Annual Meeting of the American Association for Cancer Research; 2001 Mar 24-28; New Orleans (LA). 42
    • (2001) 92nd Annual Meeting of the American Association for Cancer Research , pp. 42
    • Wood, J.M.1    Bonjean, K.2    Ruetz, S.3
  • 86
    • 0024241270 scopus 로고
    • Antibodies to parathyroid hormone-related protein lower serum calcium in athymic mouse models of malignancy-associated hypercalcemia due to human tumours
    • Kukreja SC, Shevrin DH, Wimbiscus SA, et al. Antibodies to parathyroid hormone-related protein lower serum calcium in athymic mouse models of malignancy-associated hypercalcemia due to human tumours [abstract no. 60612]. J Clin Invest 1988; 82 (5): 1798-802
    • (1988) J Clin Invest , vol.82 , Issue.5 , pp. 1798-1802
    • Kukreja, S.C.1    Shevrin, D.H.2    Wimbiscus, S.A.3
  • 87
    • 0000225984 scopus 로고    scopus 로고
    • Comparison of osteoprotegerin and pamidronate in a murine model of humoral hypercalcemia of malignancy
    • Capparaelli C, Kostenuik PJ, Morony S, et al. Comparison of osteoprotegerin and pamidronate in a murine model of humoral hypercalcemia of malignancy. J Bone Miner Res 1999; 14 Suppl. 1: S163
    • (1999) J Bone Miner Res , vol.14 , Issue.SUPPL. 1
    • Capparaelli, C.1    Kostenuik, P.J.2    Morony, S.3
  • 88
    • 0035024957 scopus 로고    scopus 로고
    • Osteoprotegerin: A physiological and pharmacological inhibitor of bone resorbtion
    • Kostenuik PJ, Shalhoub V. Osteoprotegerin: a physiological and pharmacological inhibitor of bone resorbtion. Curr Pharm Des 2001; 7: 613-35
    • (2001) Curr Pharm Des , vol.7 , pp. 613-635
    • Kostenuik, P.J.1    Shalhoub, V.2
  • 89
    • 0034662629 scopus 로고    scopus 로고
    • The vitamin D analog EB1089 prevents skeletal metastasis and prolongs survival time in nude mice transplanted with human breast cancer cells
    • El Abdaimi K, Dion N, Papavasiliou V, et al. The vitamin D analog EB1089 prevents skeletal metastasis and prolongs survival time in nude mice transplanted with human breast cancer cells. Cancer Res 2000; 60 (16): 4412-8
    • (2000) Cancer Res , vol.60 , Issue.16 , pp. 4412-4418
    • El Abdaimi, K.1    Dion, N.2    Papavasiliou, V.3
  • 90
    • 0027200251 scopus 로고
    • A vitamin D analogue (EB1089) inhibits parathyroid hormone related pepfide production and prevents the development of malignancy-associated hypercalcemia in vivo
    • Haq M, Kremer R, Goltzman D, et al. A vitamin D analogue (EB1089) inhibits parathyroid hormone related pepfide production and prevents the development of malignancy-associated hypercalcemia in vivo. J Clin Invest 1993; 91: 2416-22
    • (1993) J Clin Invest , vol.91 , pp. 2416-2422
    • Haq, M.1    Kremer, R.2    Goltzman, D.3
  • 91
    • 0033565254 scopus 로고    scopus 로고
    • Reversal of hypercalcemia with the vitamin D analogue EB1089 in a human model of squamous cancer
    • El Abdaimi K, Papavasiliou V, Rabbni SA, et al. Reversal of hypercalcemia with the vitamin D analogue EB1089 in a human model of squamous cancer. Cancer Res 1999; 59: 3325-8
    • (1999) Cancer Res , vol.59 , pp. 3325-3328
    • El Abdaimi, K.1    Papavasiliou, V.2    Rabbni, S.A.3
  • 92
    • 0030774564 scopus 로고    scopus 로고
    • Induction ofparathyroid hormone-related peptide by the ras oncogene: Role of ras farnesylation inhibitors as potential therapeutic agents for hypercalcemia malignancy
    • Aklilu F, Park M, Goltzman D, et al. Induction ofparathyroid hormone-related peptide by the ras oncogene: role of ras farnesylation inhibitors as potential therapeutic agents for hypercalcemia malignancy. Cancer Res 1997; 57: 4517-22
    • (1997) Cancer Res , vol.57 , pp. 4517-4522
    • Aklilu, F.1    Park, M.2    Goltzman, D.3
  • 93
    • 10544228130 scopus 로고    scopus 로고
    • Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases
    • Hortobagyi GN, Theriault RL, Porter L, et al. Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. N Engl J Med 1996; 335: 1785-91
    • (1996) N Engl J Med , vol.335 , pp. 1785-1791
    • Hortobagyi, G.N.1    Theriault, R.L.2    Porter, L.3
  • 94
    • 7144223389 scopus 로고    scopus 로고
    • Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate
    • Hortobagyi GN, Theriault RL, Lipton A. et al. Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate. J Clin Oncol. 1998; 16: 2038-44
    • (1998) J Clin Oncol , vol.16 , pp. 2038-2044
    • Hortobagyi, G.N.1    Theriault, R.L.2    Lipton, A.3


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