Asymmetric synthesis of substituted 2-azaspiro[3.5]nonan-1-ones: An enantioselective synthesis of the cholesterol absorption inhibitor (+)-SCH 54016

Journal of Organic Chemistry

Volumn 61, Issue 23, 1996, Pages 8341-8343

  Chen, Lian Yong ^a   Zaks, Aleksey ^a   Chackalamannil, Samuel ^a   Dugar, Sundeep ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILIPEMIC AGENT; SCH 54016; SPIRO COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENANTIOMER; REACTION ANALYSIS; TECHNIQUE;

EID: 0029798970     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo961096b     Document Type: Article

References (23)

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23. The %ee was determined on a Chiralcel OD column (95:5, hexane/2-propanol).