Synthesis of substituted 4(Z)-(methoxyimino)pentyl-1-piperidines as dual NK 1/NK 2 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 4, 2001, Pages 491-494

  Ting, Pauline C ^a   Lee, Joe F ^a   Anthes, John C ^a   Shih, Neng Yang ^a   Piwinski, John J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 [[3,5 BIS(TRIFLUOROMETHYL)PHENYL]METHOXY] 3 (3,4 DICHLOROPHENYL) 4 (METHOXYIMINO)PENTYL 1 PIPERIDINE DERIVATIVE; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ 2 RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ANALYSIS;

PIPERIDINES; RECEPTORS, NEUROKININ-1; RECEPTORS, NEUROKININ-2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035952297     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00702-2     Document Type: Article

References (12)