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11244330597
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note
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f(R) = 43.0 min.
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-
-
-
23
-
-
11244277457
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R-N-Methyl-1-phenylethylamine and (R)-N,N-dimethyl-1-phenylethylamine are much less efficient (2: er 51.5:48.5 and 50:50, respectively)
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R)-N-Methyl-1-phenylethylamine and (R)-N,N-dimethyl-1-phenylethylamine are much less efficient (2: er 51.5:48.5 and 50:50, respectively).
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-
-
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24
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0013030399
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The absolute configuration of 2 was determined by comparison of the optical rotation after radical deiodination of 2 to the known 5-methyl-5-phenyl-dihydrofuran-2-one: Albinati, A.; Bravo, P.; Ganazzoli, F.; Resnati, G.; Viani, F. J. Chem. Soc., Perkin Trans. 1 1986, 1405.
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Albinati, A.1
Bravo, P.2
Ganazzoli, F.3
Resnati, G.4
Viani, F.5
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25
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11244342398
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note
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+ was 1:1, because of the minor selectivities observed they have not been repeated using optimized conditions.
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-
-
-
26
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11244295109
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note
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4). Removal of the solvent in vacuo and purification by column chromatography on silica (pentane:methyl-tert-butyl ether 2:1) afforded 69 mg of (R)-2 (0.23 mmol, 82%) with an er of 27.5:72.5.
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-
-
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27
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11244356940
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The quadruplett of the benzylic proton in 3 was shifted to a higher field, up to a ratio of 1:1, then to lower field
-
The quadruplett of the benzylic proton in 3 was shifted to a higher field, up to a ratio of 1:1, then to lower field.
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-
-
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28
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0001511660
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The formation of a 1:1 complex was found by generating a Job plot by continuous variation of concentration, (a) Job, P. Ann. Chem. 1928, 9, 113. (b) MacCarthy, P. Anal. Chem. 1978, 50, 2165.
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Job, P.1
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29
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4244058697
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The formation of a 1:1 complex was found by generating a Job plot by continuous variation of concentration, (a) Job, P. Ann. Chem. 1928, 9, 113. (b) MacCarthy, P. Anal. Chem. 1978, 50, 2165.
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MacCarthy, P.1
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31
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0034600318
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(b) Littke, A. F.; Dai, C.; Fu, G. C. J. Am. Chem. Soc. 2000, 122, 4020.
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Littke, A.F.1
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Fu, G.C.3
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0031585045
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Gilchrist, T. L.; Kemmitt, P. D.; Germain, A. L. Tetrahedron 1997, 53, 4447.
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Germain, A.L.3
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