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Volumn 30, Issue 4, 2000, Pages 302-310

Subcutaneous adipose tissue expression of tumour necrosis factor-α is not associated with whole body insulin resistance in obese nondiabetic or in type-2 diabetic subjects

Author keywords

Cytokine; Factor ; Hyperinsulinaemic clamp; Insulin resistance; Obesity; Tumour necrosis

Indexed keywords

INSULIN; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

EID: 0006597145     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2000.00625.x     Document Type: Article
Times cited : (70)

References (35)
  • 1
    • 0024405827 scopus 로고
    • The biology of cachectin/TNF-α: A primary mediator of the host response
    • 1 Beutler B, Cerami A. The biology of cachectin/TNF-α: a primary mediator of the host response. Annu Rev Immunol 1989;7:625-55.
    • (1989) Annu Rev Immunol , vol.7 , pp. 625-655
    • Beutler, B.1    Cerami, A.2
  • 2
    • 0026075959 scopus 로고
    • Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans
    • 2 Van der Poll T, Romijn JA, Enden E et al. Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans. Am J Physiol 1991;261:E457-E465.
    • (1991) Am J Physiol , vol.261
    • Van Der Poll, T.1    Romijn, J.A.2    Enden, E.3
  • 3
    • 0026727093 scopus 로고
    • Serum tumor necrosis factor alpha and insulin resistance in gastrointestinal cancer
    • 3 McCall JL, Tuckey JA, Parry BR. Serum tumor necrosis factor alpha and insulin resistance in gastrointestinal cancer. Br J Surg 1992;79:1361-3.
    • (1992) Br J Surg , vol.79 , pp. 1361-1363
    • McCall, J.L.1    Tuckey, J.A.2    Parry, B.R.3
  • 5
    • 0041009626 scopus 로고    scopus 로고
    • Tumor necrosis factor-α acutely inhibits insulin signaling in human adipocytes. Implication of the p80 tumor necrosis factor receptor
    • 5 Liu LS, Spelleken M, Röhrig K, Hauner H, Eckel J. Tumor necrosis factor-α acutely inhibits insulin signaling in human adipocytes. Implication of the p80 tumor necrosis factor receptor. Diabetes 1998;47:515-22.
    • (1998) Diabetes , vol.47 , pp. 515-522
    • Liu, L.S.1    Spelleken, M.2    Röhrig, K.3    Hauner, H.4    Eckel, J.5
  • 6
    • 0028587742 scopus 로고
    • Tumor necrosis factor-α: A key component of the obesity-diabetes link
    • 6 Hotamisligil GS, Spiegelman BM. Tumor necrosis factor-α: a key component of the obesity-diabetes link. Diabetes 1994;43:1271-8.
    • (1994) Diabetes , vol.43 , pp. 1271-1278
    • Hotamisligil, G.S.1    Spiegelman, B.M.2
  • 7
    • 0028825748 scopus 로고
    • Tumor necrosis factor-α induced phosphorylation of insulin receptor substrate-1 (IRS-1)
    • 7 Kanery H, Feinstein R, Papa MZ, Hemi R, Karasik R, Karasik A. Tumor necrosis factor-α induced phosphorylation of insulin receptor substrate-1 (IRS-1). J Biol Chem 1995;270:23780-4.
    • (1995) J Biol Chem , vol.270 , pp. 23780-23784
    • Kanery, H.1    Feinstein, R.2    Papa, M.Z.3    Hemi, R.4    Karasik, R.5    Karasik, A.6
  • 8
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1 mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α and obesity -induced insulin resistance
    • 8 Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1 mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α and obesity -induced insulin resistance. Science 1996;271:665-8.
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 9
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
    • 9 Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 1993;259:87-91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 10
    • 0028830080 scopus 로고
    • The adipocyte: Storage depot or node on the energy information superhighway?
    • 10 Flier JS. The adipocyte: storage depot or node on the energy information superhighway? Cell 1995;80:15-8.
    • (1995) Cell , vol.80 , pp. 15-18
    • Flier, J.S.1
  • 11
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
    • 11 Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 1995;95:2111-9.
    • (1995) J Clin Invest , vol.95 , pp. 2111-2119
    • Kern, P.A.1    Saghizadeh, M.2    Ong, J.M.3    Bosch, R.J.4    Deem, R.5    Simsolo, R.B.6
  • 12
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance
    • 12 Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest 1995;95:2409-15.
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 13
    • 0031026510 scopus 로고    scopus 로고
    • Increased adipose tissue PC-1 protein content, but not tumour necrosis factor-α gene expression, is associated with a reduction of both whole body insulin sensitivity and insulin receptor tyrosine-kinase activity
    • 13 Frittitta L, Youngren JF, Sbraccia P et al. Increased adipose tissue PC-1 protein content, but not tumour necrosis factor-α gene expression, is associated with a reduction of both whole body insulin sensitivity and insulin receptor tyrosine-kinase activity. Diabetologia 1997;40:282-9.
    • (1997) Diabetologia , vol.40 , pp. 282-289
    • Frittitta, L.1    Youngren, J.F.2    Sbraccia, P.3
  • 14
    • 0029906375 scopus 로고    scopus 로고
    • Effects of an engineered human anti-TNFα antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
    • 14 Ofei F, Hurel S, Newkirk J, Sopwith M, Taylor R. Effects of an engineered human anti-TNFα antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes 1996;45:881-5.
    • (1996) Diabetes , vol.45 , pp. 881-885
    • Ofei, F.1    Hurel, S.2    Newkirk, J.3    Sopwith, M.4    Taylor, R.5
  • 15
    • 0030481074 scopus 로고    scopus 로고
    • Circulating TNF-alpha and leptin levels in offspring of NIDDM patients do not correlate to individual insulin sensitivity
    • 15 Kellerer M, Rett K, Renn W, Groop L, Häring HU. Circulating TNF-alpha and leptin levels in offspring of NIDDM patients do not correlate to individual insulin sensitivity. Horm Metab Res 1996;28:737-43.
    • (1996) Horm Metab Res , vol.28 , pp. 737-743
    • Kellerer, M.1    Rett, K.2    Renn, W.3    Groop, L.4    Häring, H.U.5
  • 16
    • 0030978036 scopus 로고    scopus 로고
    • Circulating tumor necrosis factor α is elevated in male but not in female patients with type II diabetes mellitus
    • 16 Pfeiffer A, Janott J, Möhlig M et al. Circulating tumor necrosis factor α is elevated in male but not in female patients with type II diabetes mellitus. Horm Metab Res 1997;29:111-4.
    • (1997) Horm Metab Res , vol.29 , pp. 111-114
    • Pfeiffer, A.1    Janott, J.2    Möhlig, M.3
  • 17
    • 15644362064 scopus 로고    scopus 로고
    • Serum levels of tumor necrosis factor-α are increased in obese patients with noninsulin-dependent diabetes mellitus
    • 17 Katsuki A, Sumida Y, Murashima S et al. Serum levels of tumor necrosis factor-α are increased in obese patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1998;83:859-62.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 859-862
    • Katsuki, A.1    Sumida, Y.2    Murashima, S.3
  • 18
    • 0031838312 scopus 로고    scopus 로고
    • Elevated serum tumour necrosis factor-alpha levels can contribute to the insulin resistance in type II (noninsulin-dependent) diabetes and in obesity
    • 18 Winkler G, Salamon F, Salamon D, Speer G, Simon K, Cseh K. Elevated serum tumour necrosis factor-alpha levels can contribute to the insulin resistance in Type II (noninsulin-dependent) diabetes and in obesity (Letter). Diabetologia 1998;41:860-1.
    • (1998) Diabetologia , vol.41 , pp. 860-861
    • Winkler, G.1    Salamon, F.2    Salamon, D.3    Speer, G.4    Simon, K.5    Cseh, K.6
  • 19
    • 0031867918 scopus 로고    scopus 로고
    • Relation between plasma tumor necrosis factor-α and insulin sensitivity in elderly men with non-insulin-dependent diabetes mellitus
    • 19 Nilsson J, Jovinge S, Niemann A, Reneland R, Lithell H. Relation between plasma tumor necrosis factor-α and insulin sensitivity in elderly men with non-insulin-dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1998;18:1199-202.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1199-1202
    • Nilsson, J.1    Jovinge, S.2    Niemann, A.3    Reneland, R.4    Lithell, H.5
  • 20
    • 0018520840 scopus 로고
    • Glucose clamp technique: A method for quantifying insulin secretion and resistance
    • 20 DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979;237:E214-E223.
    • (1979) Am J Physiol , vol.237
    • DeFronzo, R.A.1    Tobin, J.D.2    Andres, R.3
  • 21
    • 0028954348 scopus 로고
    • Athletes with IDDM exhibit impaired metabolic control and increased lipid utilization with no increase in insulin sensitivity
    • 21 Ebeling P, Tuominen JA, Bourey R, Koranyi L, Koivisto VA. Athletes with IDDM exhibit impaired metabolic control and increased lipid utilization with no increase in insulin sensitivity. Diabetes 1995;44:471-7.
    • (1995) Diabetes , vol.44 , pp. 471-477
    • Ebeling, P.1    Tuominen, J.A.2    Bourey, R.3    Koranyi, L.4    Koivisto, V.A.5
  • 22
    • 1842334456 scopus 로고    scopus 로고
    • Report of the expert committee on the diagnosis and classification of diabetes mellitus
    • 22 The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997;20:1183-97.
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 23
    • 0030055611 scopus 로고    scopus 로고
    • The expression of ob gene is not acutely regulated by insulin and fasting in human abdominal subcutaneous adipose tissue
    • 23 Vidal H, Auboeuf D, De Vos P et al. The expression of ob gene is not acutely regulated by insulin and fasting in human abdominal subcutaneous adipose tissue. J Clin Invest 1996;98:251-5.
    • (1996) J Clin Invest , vol.98 , pp. 251-255
    • Vidal, H.1    Auboeuf, D.2    De Vos, P.3
  • 24
    • 0031568947 scopus 로고    scopus 로고
    • The use of the reverse transcription-competitive polymerase chain reaction to investigate the in vivo regulation of gene expression in small tissue samples
    • 24 Auboeuf D, Vidal H. The use of the reverse transcription-competitive polymerase chain reaction to investigate the in vivo regulation of gene expression in small tissue samples. Anal Biochem 1997;245:141-8.
    • (1997) Anal Biochem , vol.245 , pp. 141-148
    • Auboeuf, D.1    Vidal, H.2
  • 25
    • 0030747895 scopus 로고    scopus 로고
    • Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α in humans: No alteration in adipose tissue of obese and NIDDM patients
    • 25 Auboeuf D, Rieusset J, Fajas L et al. Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-α in humans: No alteration in adipose tissue of obese and NIDDM patients. Diabetes 1997;46:1319-27.
    • (1997) Diabetes , vol.46 , pp. 1319-1327
    • Auboeuf, D.1    Rieusset, J.2    Fajas, L.3
  • 26
    • 0031437096 scopus 로고    scopus 로고
    • Increased uncoupling protein-2 and -3 mRNA expression during fasting in obese and lean humans
    • 26 Millet L, Vidal H, Andreelli F et al. Increased Uncoupling Protein-2 and -3 mRNA expression during fasting in obese and lean humans. J Clin Invest 1997;100:2665-70.
    • (1997) J Clin Invest , vol.100 , pp. 2665-2670
    • Millet, L.1    Vidal, H.2    Andreelli, F.3
  • 27
    • 0021681058 scopus 로고
    • Human tumour necrosis factor: Precursor structure, expression and homology to lymphotoxin
    • 27 Pennica D, Nedwin GE, Hayflick JS et al. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature 1984;312:724-9.
    • (1984) Nature , vol.312 , pp. 724-729
    • Pennica, D.1    Nedwin, G.E.2    Hayflick, J.S.3
  • 28
    • 0026858708 scopus 로고
    • Direct stimulation of cytokines (IL-1β, TNF-α, IL-6, IL-2, IFN-γ and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation
    • 28 De Groote D, Zangerle PF, Gevaert Y et al. Direct stimulation of cytokines (IL-1β, TNF-α, IL-6, IL-2, IFN-γ and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation. Cytokine 1992;4:239-48.
    • (1992) Cytokine , vol.4 , pp. 239-248
    • De Groote, D.1    Zangerle, P.F.2    Gevaert, Y.3
  • 30
    • 0013662373 scopus 로고    scopus 로고
    • Subcutaneous adipose tissue PAI-1 gene expression has a diurnal variation and it correlates with obesity and insulin resistance
    • (Abstract) 1368
    • 30 Koistinen H, Ebeling P, Tuominen JA, Valuer P, Laville M, Koivisto VA et al. Subcutaneous adipose tissue PAI-1 gene expression has a diurnal variation and it correlates with obesity and insulin resistance. Diabetes 1999;48 (Suppl. 1):A313 ((Abstract) 1368).
    • (1999) Diabetes , vol.48 , Issue.SUPPL. 1
    • Koistinen, H.1    Ebeling, P.2    Tuominen, J.A.3    Valuer, P.4    Laville, M.5    Koivisto, V.A.6
  • 31
    • 0024026298 scopus 로고
    • The triumvirate: β-cell, muscle, liver. A collusion responsible for NIDDM
    • 31 DeFronzo RA. The triumvirate: β-cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 1988;37: 667-87.
    • (1988) Diabetes , vol.37 , pp. 667-687
    • DeFronzo, R.A.1
  • 32
    • 0031678588 scopus 로고    scopus 로고
    • Depot-related gene expression in human subcutaneous and omental adipocytes
    • 32 Montague CT, Prins JB, Sanders L et al. Depot-related gene expression in human subcutaneous and omental adipocytes. Diabetes 1998;47:1384-91.
    • (1998) Diabetes , vol.47 , pp. 1384-1391
    • Montague, C.T.1    Prins, J.B.2    Sanders, L.3
  • 33
    • 13344295079 scopus 로고    scopus 로고
    • Serum immunoreactive leptin concentrations in normal-weight and obese humans
    • 33 Considine RV, Sinha MK, Heiman ML et al. Serum immunoreactive leptin concentrations in normal-weight and obese humans. N Engl J Med 1996;334:292-5.
    • (1996) N Engl J Med , vol.334 , pp. 292-295
    • Considine, R.V.1    Sinha, M.K.2    Heiman, M.L.3
  • 35
    • 0030735542 scopus 로고    scopus 로고
    • Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo
    • 35 Mohamed-Ali V, Goodrick S, Rawesh A et al. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo. J Clin Endocrinol Metab 1997;82: 4196-200.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4196-4200
    • Mohamed-Ali, V.1    Goodrick, S.2    Rawesh, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.