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Volumn 40, Issue 2, 2000, Pages 99-107

Ataxic mutant mice with defects in Ca2+ channel α1A subunit gene: Morphological and functional abnormalities in cerebellar cortical neurons

Author keywords

Ataxia; Ca2+ channel; Leaner mouse; Purkinje cells; Rolling mouse Nagoya; Tottering mouse; Tyrosine hydroxylase

Indexed keywords


EID: 0006197783     PISSN: 09143505     EISSN: 17414520     Source Type: Journal    
DOI: 10.1111/j.1741-4520.2000.tb00913.x     Document Type: Review
Times cited : (14)

References (63)
  • 1
    • 0030059611 scopus 로고    scopus 로고
    • Co-localization of tyrosine hydroxylase and Zebrin II immunoreactivities in Purkinje cells of the mutant mice, tottering and tottering/leaner
    • Abbott LC, Isaacs KR, Heckroth JA (1996) Co-localization of tyrosine hydroxylase and Zebrin II immunoreactivities in Purkinje cells of the mutant mice, tottering and tottering/leaner. Neuroscience, 71: 461-475.
    • (1996) Neuroscience , vol.71 , pp. 461-475
    • Abbott, L.C.1    Isaacs, K.R.2    Heckroth, J.A.3
  • 3
    • 0025203440 scopus 로고
    • Neuromodulatory effects of corticotropin releasing factor on cerebellar Purkinje cells: An in vivo study in the cat
    • Bishop GA (1990) Neuromodulatory effects of corticotropin releasing factor on cerebellar Purkinje cells: an in vivo study in the cat. Neuroscience, 39: 251-257.
    • (1990) Neuroscience , vol.39 , pp. 251-257
    • Bishop, G.A.1
  • 4
    • 0026652764 scopus 로고
    • Differential modulation of Purkinje cell activity by enkephalin and corticotropin releasing factor
    • Bishop GA, King JS (1992) Differential modulation of Purkinje cell activity by enkephalin and corticotropin releasing factor. Neuropeptides, 22: 167-174.
    • (1992) Neuropeptides , vol.22 , pp. 167-174
    • Bishop, G.A.1    King, J.S.2
  • 5
    • 0032895055 scopus 로고    scopus 로고
    • L-type calcium channels contribute to the tottering mouse dystonic episodes
    • Campbell DB, Hess EJ (1999) L-type calcium channels contribute to the tottering mouse dystonic episodes. Mol Pharmacol, 55: 23-31.
    • (1999) Mol Pharmacol , vol.55 , pp. 23-31
    • Campbell, D.B.1    Hess, E.J.2
  • 7
    • 0032189427 scopus 로고    scopus 로고
    • Whole-cell and single-channel analysis of P-type calcium currents in cerebellar Purkinje cells of leaner mutant mice
    • Dove LS, Abbott LC, Griffith WH (1998) Whole-cell and single-channel analysis of P-type calcium currents in cerebellar Purkinje cells of leaner mutant mice. J Neurosci, 18: 7687-7699.
    • (1998) J Neurosci , vol.18 , pp. 7687-7699
    • Dove, L.S.1    Abbott, L.C.2    Griffith, W.H.3
  • 8
    • 0031959948 scopus 로고    scopus 로고
    • Ataxia, arrhythmia and ion-channel gene defects
    • Doyle JL, Stubbs L (1998) Ataxia, arrhythmia and ion-channel gene defects. Trends Genet, 14: 92-98.
    • (1998) Trends Genet , vol.14 , pp. 92-98
    • Doyle, J.L.1    Stubbs, L.2
  • 10
    • 0033008050 scopus 로고    scopus 로고
    • L-type calcium channel regulation of abnormal tyrosine hydroxylase expression in cerebella of tottering mice
    • Fureman BE, Campbell DB, Hess EJ (1999) L-type calcium channel regulation of abnormal tyrosine hydroxylase expression in cerebella of tottering mice. Ann N Y Acad Sci, 868: 217-219.
    • (1999) Ann N Y Acad Sci , vol.868 , pp. 217-219
    • Fureman, B.E.1    Campbell, D.B.2    Hess, E.J.3
  • 11
    • 0000150288 scopus 로고
    • Tottering-a neuromuscular mutation in the mouse
    • Green MC, Sidman RL (1962) Tottering-a neuromuscular mutation in the mouse. J Hered, 53: 233-237.
    • (1962) J Hered , vol.53 , pp. 233-237
    • Green, M.C.1    Sidman, R.L.2
  • 12
    • 0030972578 scopus 로고    scopus 로고
    • Peptide localization in the mouse inferior olive
    • Gregg, KV, Bishop GA (1997) Peptide localization in the mouse inferior olive. J Chem Neuroanat, 12: 211-220.
    • (1997) J Chem Neuroanat , vol.12 , pp. 211-220
    • Gregg, K.V.1    Bishop, G.A.2
  • 13
    • 0028841791 scopus 로고
    • Electorophysiology and GABA-immunocytochemistry in the vestibular nuclei of normal (C57BL/6J) and Leaner mutant mice
    • Grüsser-Cornehls U, Luy M, Bäurle J (1995) Electorophysiology and GABA-immunocytochemistry in the vestibular nuclei of normal (C57BL/6J) and Leaner mutant mice. Brain Res, 703: 51-62.
    • (1995) Brain Res , vol.703 , pp. 51-62
    • Grüsser-Cornehls, U.1    Luy, M.2    Bäurle, J.3
  • 14
    • 0020628249 scopus 로고
    • Hyperspiny Purkinje cell, a new neurological mutation in the mouse
    • Guénet JL, Sotelo C, Mariani J (1983) Hyperspiny Purkinje cell, a new neurological mutation in the mouse. J Hered, 74: 105-108.
    • (1983) J Hered , vol.74 , pp. 105-108
    • Guénet, J.L.1    Sotelo, C.2    Mariani, J.3
  • 15
    • 0027978578 scopus 로고
    • Purkinje cell loss from alternating sagittal zones in the cerebellum of leaner mutant mice
    • Heckroth JA, Abbott LC (1994) Purkinje cell loss from alternating sagittal zones in the cerebellum of leaner mutant mice. Brain Res, 658: 93-104.
    • (1994) Brain Res , vol.658 , pp. 93-104
    • Heckroth, J.A.1    Abbott, L.C.2
  • 16
    • 0019949253 scopus 로고
    • Cerebellar cell degeneration in the leaner mutant mouse
    • Herrup K, Wilczynski SL (1982) Cerebellar cell degeneration in the leaner mutant mouse. Neuroscience, 7: 2185-2196.
    • (1982) Neuroscience , vol.7 , pp. 2185-2196
    • Herrup, K.1    Wilczynski, S.L.2
  • 17
    • 0026026842 scopus 로고
    • Tottering and leaner mutations perturb transient developmental expression of tyrosine hydroxylase in embryologically distinct Purkinje cells
    • Hess EJ, Wilson MC (1991) Tottering and leaner mutations perturb transient developmental expression of tyrosine hydroxylase in embryologically distinct Purkinje cells. Neuron, 6: 123-132.
    • (1991) Neuron , vol.6 , pp. 123-132
    • Hess, E.J.1    Wilson, M.C.2
  • 18
    • 0021059199 scopus 로고
    • Effects of disruption of microtubules on translocation of particles and morphology in tissue cultured neurites
    • Horie H, Takenaka T, Kaiho M (1983) Effects of disruption of microtubules on translocation of particles and morphology in tissue cultured neurites. Brain Res, 288: 85-93.
    • (1983) Brain Res , vol.288 , pp. 85-93
    • Horie, H.1    Takenaka, T.2    Kaiho, M.3
  • 19
    • 0027000613 scopus 로고
    • Development of the paramedian lobule of the cerebellum in wild-type and tottering mice
    • Isaacs KR, Abbott LC (1992) Development of the paramedian lobule of the cerebellum in wild-type and tottering mice. Dev Neurosci, 14: 386-393.
    • (1992) Dev Neurosci , vol.14 , pp. 386-393
    • Isaacs, K.R.1    Abbott, L.C.2
  • 20
    • 0028816864 scopus 로고
    • Cerebellar volume decreases in the tottering mouse are specific to the molecular layer
    • Isaacs KR, Abbott LC (1995) Cerebellar volume decreases in the tottering mouse are specific to the molecular layer. Brain Res Bull, 36: 309-314.
    • (1995) Brain Res Bull , vol.36 , pp. 309-314
    • Isaacs, K.R.1    Abbott, L.C.2
  • 22
    • 0025118385 scopus 로고
    • Distribution and brainstem origin of cholecystokinin-like immunoreactivity in the opossum cerebellum
    • King JS, Bishop GA (1990) Distribution and brainstem origin of cholecystokinin-like immunoreactivity in the opossum cerebellum. J Comp Neurol, 298: 373-384.
    • (1990) J Comp Neurol , vol.298 , pp. 373-384
    • King, J.S.1    Bishop, G.A.2
  • 23
    • 0019118826 scopus 로고
    • Noradrenaline metabolism in the brain of rolling mouse Nagoya and the influence of thyrotropin releasing hormone
    • Japanese
    • Konagaya M, Takayanagi T, Muroga T, Adachi K, Sobue I (1980) Noradrenaline metabolism in the brain of rolling mouse Nagoya and the influence of thyrotropin releasing hormone. Clin Neurol, 20: 181-188. (Japanese)
    • (1980) Clin Neurol , vol.20 , pp. 181-188
    • Konagaya, M.1    Takayanagi, T.2    Muroga, T.3    Adachi, K.4    Sobue, I.5
  • 24
    • 0032524625 scopus 로고    scopus 로고
    • Hotfoot mouse mutations affect the 2 glutamate receptor gene and are allelic to Lurcher
    • Lalouette A, Guénet JL, Vriz S (1998) Hotfoot mouse mutations affect the 2 glutamate receptor gene and are allelic to Lurcher. Genomics, 50: 9-13.
    • (1998) Genomics , vol.50 , pp. 9-13
    • Lalouette, A.1    Guénet, J.L.2    Vriz, S.3
  • 26
    • 0019795066 scopus 로고
    • Mutant mouse tottering: selective increase of locus ceruleus axons in a defined single-locus mutation
    • Levitt P, Noebels JL (1981) Mutant mouse tottering: selective increase of locus ceruleus axons in a defined single-locus mutation. Proc Natl Acad Sci USA, 78: 4630-4634.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 4630-4634
    • Levitt, P.1    Noebels, J.L.2
  • 27
    • 0029117733 scopus 로고
    • Inability to restore resting intracellular calcium levels as an early indicator of delayed neuronal cell death
    • Limbrick DD Jr, Churn SB, Sombati S, Delorenzo RJ (1995) Inability to restore resting intracellular calcium levels as an early indicator of delayed neuronal cell death. Brain Res, 690: 145-156.
    • (1995) Brain Res , vol.690 , pp. 145-156
    • Limbrick Jr., D.D.1    Churn, S.B.2    Sombati, S.3    Delorenzo, R.J.4
  • 28
    • 0032526434 scopus 로고    scopus 로고
    • Altered calcium channel currents in Purkinje cells of the neurological mutant mouse leaner
    • Lorenzon NM, Lutz CM, Frankel WN, Beam KG (1998) Altered calcium channel currents in Purkinje cells of the neurological mutant mouse leaner. J Neurosci, 18: 4482-4489.
    • (1998) J Neurosci , vol.18 , pp. 4482-4489
    • Lorenzon, N.M.1    Lutz, C.M.2    Frankel, W.N.3    Beam, K.G.4
  • 29
    • 0027298996 scopus 로고
    • Levels of somatostatin and cholecystokinin in the brain of ataxic mutant mice
    • Matsui K, Masui A, Kato N, Adachi K (1993) Levels of somatostatin and cholecystokinin in the brain of ataxic mutant mice. Life Sci, 53: 333-340.
    • (1993) Life Sci , vol.53 , pp. 333-340
    • Matsui, K.1    Masui, A.2    Kato, N.3    Adachi, K.4
  • 30
    • 0015116941 scopus 로고
    • Three syndromes produced by two mutant genes in the mouse. Clinical, pathological, and ultrastructural bases of tottering, leaner, and heterozygous mice
    • Meier H, MacPike AD (1971) Three syndromes produced by two mutant genes in the mouse. Clinical, pathological, and ultrastructural bases of tottering, leaner, and heterozygous mice. J Hered, 62: 297-302.
    • (1971) J Hered , vol.62 , pp. 297-302
    • Meier, H.1    MacPike, A.D.2
  • 31
    • 0025923115 scopus 로고
    • 2+ homeostasis
    • Miller RJ (1991) The control of neuronal Ca2+ homeostasis. Prog Neurobiol, 37: 255-285.
    • (1991) Prog Neurobiol , vol.37 , pp. 255-285
    • Miller, R.J.1
  • 33
    • 0032890450 scopus 로고    scopus 로고
    • Monoaminergic long term facilitation of GABA-mediated inhibitory transmission at cerebellar synapses
    • Mitoma H, Konishi S (1999) Monoaminergic long term facilitation of GABA-mediated inhibitory transmission at cerebellar synapses. Neuroscience, 88: 871-883.
    • (1999) Neuroscience , vol.88 , pp. 871-883
    • Mitoma, H.1    Konishi, S.2
  • 34
    • 0033118629 scopus 로고    scopus 로고
    • Corticotropin-releasing factor plays a permissive role in cerebellar long-term depression
    • Miyata M, Okada D, Hashimoto K, Kano M, Ito M (1999) Corticotropin- releasing factor plays a permissive role in cerebellar long-term depression. Neuron, 22: 763-775.
    • (1999) Neuron , vol.22 , pp. 763-775
    • Miyata, M.1    Okada, D.2    Hashimoto, K.3    Kano, M.4    Ito, M.5
  • 35
    • 0019497493 scopus 로고
    • Neurotransmitter abnormality in Rolling mouse Nagoya, an ataxic mutant mouse
    • Muramoto O, Kanazawa I, Ando K (1981) Neurotransmitter abnormality in Rolling mouse Nagoya, an ataxic mutant mouse. Brain Res, 215: 295-304.
    • (1981) Brain Res , vol.215 , pp. 295-304
    • Muramoto, O.1    Kanazawa, I.2    Ando, K.3
  • 36
    • 0020057160 scopus 로고
    • Central noradrenaline metabolism in cerebellar ataxic mice
    • Muramoto O, Ando K, Kanazawa I (1982) Central noradrenaline metabolism in cerebellar ataxic mice. Brain Res, 237: 387-395.
    • (1982) Brain Res , vol.237 , pp. 387-395
    • Muramoto, O.1    Ando, K.2    Kanazawa, I.3
  • 37
    • 0031054257 scopus 로고    scopus 로고
    • Tyrosine hydroxylase gene promoter activity is regulated by both cyclic AMP-responsive element and API sites following calcium influx
    • Nagamoto-Combs K, Piech KM, Best JA, Sun B, Tank AW (1997) Tyrosine hydroxylase gene promoter activity is regulated by both cyclic AMP-responsive element and API sites following calcium influx. J Biol Chem, 272: 6051-6058.
    • (1997) J Biol Chem , vol.272 , pp. 6051-6058
    • Nagamoto-Combs, K.1    Piech, K.M.2    Best, J.A.3    Sun, B.4    Tank, A.W.5
  • 38
    • 0030024171 scopus 로고    scopus 로고
    • Promoter elements and second messenger pathways involved in transcriptional activation of tyrosine hydroxylase by ionomycin
    • Nankova B, Hiremagalur B, Menezes A, Zeman R, Sabban E (1996) Promoter elements and second messenger pathways involved in transcriptional activation of tyrosine hydroxylase by ionomycin. Mol Brain Res, 35: 164-172.
    • (1996) Mol Brain Res , vol.35 , pp. 164-172
    • Nankova, B.1    Hiremagalur, B.2    Menezes, A.3    Zeman, R.4    Sabban, E.5
  • 39
    • 0031044123 scopus 로고    scopus 로고
    • Distribution of tyrosine hydroxylase-immunoreactive afferents to the cerebellum differs between species
    • Nelson TE, King JS, Bishop GA (1997) Distribution of tyrosine hydroxylase-immunoreactive afferents to the cerebellum differs between species. J Comp Neurol, 379: 443-454.
    • (1997) J Comp Neurol , vol.379 , pp. 443-454
    • Nelson, T.E.1    King, J.S.2    Bishop, G.A.3
  • 40
    • 0016774926 scopus 로고
    • The cerebellum of rolling mouse Nagoya
    • Japanese
    • Nishimura Y (1975) The cerebellum of rolling mouse Nagoya. Adv Neurol Sci, 19: 670-672. (Japanese)
    • (1975) Adv Neurol Sci , vol.19 , pp. 670-672
    • Nishimura, Y.1
  • 41
    • 0018416478 scopus 로고
    • Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering
    • Noebels JL, Sidman RL (1979) Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering. Science, 204: 1334-1336.
    • (1979) Science , vol.204 , pp. 1334-1336
    • Noebels, J.L.1    Sidman, R.L.2
  • 42
    • 84909753001 scopus 로고
    • The observation of rolling mouse Nagoya (rol), a new neurological mutant, and its maintenance
    • Japanese
    • Oda S (1973) The observation of rolling mouse Nagoya (rol), a new neurological mutant, and its maintenance. Exp Anim, 22: 281-286. (Japanese)
    • (1973) Exp Anim , vol.22 , pp. 281-286
    • Oda, S.1
  • 45
    • 0032893891 scopus 로고    scopus 로고
    • la mice
    • Rhyu IJ, Abbott LC, Walker DB, Sotelo C (1999a) An ultrastructural study of granule cell/Purkinje cell synapses in tottering (tg/tg),leaner (tgla/tgla) and compound heterozygous tottering/leaner (tg/tgla) mice. Neuroscience, 90: 717-728.
    • (1999) Neuroscience , vol.90 , pp. 717-728
    • Rhyu, I.J.1    Abbott, L.C.2    Walker, D.B.3    Sotelo, C.4
  • 46
    • 0344299283 scopus 로고    scopus 로고
    • rol cerebellar Purkinje cells: An ataxic mutant revisited
    • Rhyu IJ, Oda S, Uhm C-S, Kim H, Suh Y-S, Abbott LC (1999b) Morphologic investigation of rolling mouse Nagoya (tgrol/tgrol) cerebellar Purkinje cells: an ataxic mutant revisited. Neurosci Lett, 266: 49-52.
    • (1999) Neurosci Lett , vol.266 , pp. 49-52
    • Rhyu, I.J.1    Oda, S.2    Uhm, C.-S.3    Kim, H.4    Suh, Y.-S.5    Abbott, L.C.6
  • 47
  • 48
    • 0027237602 scopus 로고
    • Distinctive biophysical and pharmacological properties of class A (BI) calcium channel alpha 1 subunit
    • Sather WA, Tanabe T, Zhang JF, Mori Y, Adams ME, Tsien RW (1993) Distinctive biophysical and pharmacological properties of class A (BI) calcium channel alpha 1 subunit. Neuron, 11: 291-303.
    • (1993) Neuron , vol.11 , pp. 291-303
    • Sather, W.A.1    Tanabe, T.2    Zhang, J.F.3    Mori, Y.4    Adams, M.E.5    Tsien, R.W.6
  • 49
    • 0033594796 scopus 로고    scopus 로고
    • Abnormal expression of tyrosine hydroxylase immunoreactivity in cerebellar cortex of ataxic mutant mice
    • Sawada K, Komatsu S, Haga H, Sun X-Z, Hisano S, Fukui Y (1999a) Abnormal expression of tyrosine hydroxylase immunoreactivity in cerebellar cortex of ataxic mutant mice. Brain Res, 829: 107-112.
    • (1999) Brain Res , vol.829 , pp. 107-112
    • Sawada, K.1    Komatsu, S.2    Haga, H.3    Sun, X.-Z.4    Hisano, S.5    Fukui, Y.6
  • 50
    • 0032861945 scopus 로고    scopus 로고
    • Abnormal expression of tyrosine hydroxylase immunoreactivity in Purkinje cells precedes the onset of ataxia in dilute-lethal mice
    • Sawada K, Komatsu S, Haga H, Oda S, Fukui Y (1999b) Abnormal expression of tyrosine hydroxylase immunoreactivity in Purkinje cells precedes the onset of ataxia in dilute-lethal mice. Brain Res, 844: 188-191.
    • (1999) Brain Res , vol.844 , pp. 188-191
    • Sawada, K.1    Komatsu, S.2    Haga, H.3    Oda, S.4    Fukui, Y.5
  • 51
    • 0030048838 scopus 로고    scopus 로고
    • Calcium-dependent interaction of N-type calcium channels with the synaptic core complex
    • Sheng Z-H, Rettig J, Cook T, Catterall WA (1996) Calcium-dependent interaction of N-type calcium channels with the synaptic core complex. Nature, 379: 451-454.
    • (1996) Nature , vol.379 , pp. 451-454
    • Sheng, Z.-H.1    Rettig, J.2    Cook, T.3    Catterall, W.A.4
  • 52
    • 0028595727 scopus 로고
    • Identification of a syntaxin-binding site on N-type calcium channels
    • Sheng Z-H, Rettig J, Takahashi M, Catterall WA (1994) Identification of a syntaxin-binding site on N-type calcium channels. Neuron, 13: 1303-1313.
    • (1994) Neuron , vol.13 , pp. 1303-1313
    • Sheng, Z.-H.1    Rettig, J.2    Takahashi, M.3    Catterall, W.A.4
  • 53
    • 0007637317 scopus 로고
    • Nodding, a new mutant of the mouse with cerebellar abnormalities
    • Sotelo C, Guénet JL (1983) Nodding, a new mutant of the mouse with cerebellar abnormalities. Neurosci Lett, 14: S353.
    • (1983) Neurosci Lett , vol.14
    • Sotelo, C.1    Guénet, J.L.2
  • 56
    • 0028937345 scopus 로고
    • 2+ -channels: Four subtypes of α1- and β-subunits in developing and mature rat brain
    • Tanaka O, Sakagami H, Kondo H (1995) Localization of mRNAs of voltage-dependent Ca2+-channels: four subtypes of α1- and β-subunits in developing and mature rat brain. Mol Brain Res, 30: 1-16.
    • (1995) Mol Brain Res , vol.30 , pp. 1-16
    • Tanaka, O.1    Sakagami, H.2    Kondo, H.3
  • 58
    • 0015019475 scopus 로고
    • Evidence for allelism of leaner and tottering in the mouse
    • Tsuji S, Meier H (1971) Evidence for allelism of leaner and tottering in the mouse. Genet Res Camb, 17: 83-88.
    • (1971) Genet Res Camb , vol.17 , pp. 83-88
    • Tsuji, S.1    Meier, H.2
  • 60
    • 0027081672 scopus 로고
    • Rolling mouse Nagoya as a mutant animal model of basal ganglia dysfunction: determination of absolute rates of local cerebral glucose utilization
    • Yamaguchi T, Kato M, Fukui M, Akazawa K (1992) Rolling mouse Nagoya as a mutant animal model of basal ganglia dysfunction: determination of absolute rates of local cerebral glucose utilization. Brain Res, 589: 38-44.
    • (1992) Brain Res , vol.589 , pp. 38-44
    • Yamaguchi, T.1    Kato, M.2    Fukui, M.3    Akazawa, K.4
  • 61
    • 0018246399 scopus 로고
    • Neurofibrillary pathology: Current status and research perspectives
    • Wisniewski HM, Soifer D (1979) Neurofibrillary pathology: current status and research perspectives. Mech Ageing Dev, 9: 119-142.
    • (1979) Mech Ageing Dev , vol.9 , pp. 119-142
    • Wisniewski, H.M.1    Soifer, D.2
  • 62
    • 0023915936 scopus 로고
    • Inhibition of climbing and mossy fiber input to mouse cerebellar Purkinje cells by cholecystokinin
    • Wood PL, Steel DJ, Kim HS, Petrack B, Altar CA (1988) Inhibition of climbing and mossy fiber input to mouse cerebellar Purkinje cells by cholecystokinin. J Pharmacol Exp Ther, 244: 58-62.
    • (1988) J Pharmacol Exp Ther , vol.244 , pp. 58-62
    • Wood, P.L.1    Steel, D.J.2    Kim, H.S.3    Petrack, B.4    Altar, C.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.