Whole-cell and single-channel analysis of P-type calcium currents in cerebellar Purkinje cells of leaner mutant mice

Journal of Neuroscience

Volumn 18, Issue 19, 1998, Pages 7687-7699

  Dove, Leonard S ^a   Abbott, Louise C ^b   Griffith, William H ^a  

^a TEXAS A M COLLEGE OF MEDICINE   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Calcium channel; Leaner; Mouse; Neurological mutant; Purkinje cell; Single channel

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATAXIA; CALCIUM CURRENT; CEREBELLUM; CHANNEL GATING; CONTROLLED STUDY; FEMALE; GENE MUTATION; MALE; MEMBRANE CONDUCTANCE; MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; STRUCTURE ACTIVITY RELATION;

EID: 0032189427     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-19-07687.1998     Document Type: Article

References (8)

1. Bean BP (1989) Classes of calcium channels in vertebrate cells. Annu Rev Physiol 51:367-384.
2. Berrow NS, Brice NL, Tedder I, Page KM, Dolphin AC (1997) Properties of cloned rat α1A calcium channels transiently expressed in the COS-7 cell line. Eur J Neurosci 9:739-748.
3. Birnbaumer L, Campbell KP, Catterall WA, Harpold MM, Hofmann F, Horne WA, Mori Y, Schwartz A, Snutch TP, Tanabe T, Tsien RW (1994) The naming of voltage-gated calcium channels. Neuron 13:505-506.
4. Mintz IM, Venema VJ, Swiderek KM, Lee TD, Bean BP, Adams ME (1992a) P-type calcium channels blocked by the spider toxin ω-Aga-IVA. Nature 355:827-829.
5. Mintz IM, Adams ME, Bean BP (1992b) P-type calcium channels in rat central and peripheral neurons. Neuron 9:85-95.
6. Moreno H, Rudy B, Llinas R (1997) β subunits influence the biophysical and pharmacological differences between the P- and Q-type calcium currents expressed in a mammalian cell line. Proc Natl Acad Sci USA 94:14042-14047.
7. Mori Y, Friedrich T, Kim M-S, Mikami A, Nakai J, Ruth P, Boss E, Hofmann F, Flockerzi V, Furuichi T, Mikoshiba K, Imoto K, Tanabe T, Numa S (1991) Primary structure and functional expression from complementary DNA of a brain calcium channel. Nature 350:398-402.
8. Mori Y, Mikala G, Varadi G, Kobayashi T, Koch S, Wakamori M, Schwartz A (1996) Molecular pharmacology of voltage-dependent calcium channels. Jpn J Pharmacol 72:83-109.