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Volumn 1, Issue 1, 2002, Pages 46-54

Preweaning enrichment has no lasting effects on adult hippocampal neurogenesis in four-month-old mice

Author keywords

BrdU; Enriched environment; Mouse; Neonatal handling; Progenitor cells; Stem cells

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN SIZE; CELL COUNT; CELL LABELING; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DENTATE GYRUS; ENVIRONMENTAL FACTOR; EXPLORATORY BEHAVIOR; FEMALE; GRANULE CELL; HIPPOCAMPUS; LOCOMOTION; MOUSE; NEWBORN; NONHUMAN; PHYSICAL ACTIVITY; PLASTICITY; POSTNATAL DEVELOPMENT; PREWEANING ENRICHMENT; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STEREOMETRY; STIMULUS RESPONSE; VOLUMETRY; WEANING; ANIMAL; BODY WEIGHT; CYTOLOGY; ENVIRONMENT; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; MOTOR ACTIVITY; NERVE CELL; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; SUCKLING;

EID: 0002838504     PISSN: 16011848     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1601-1848.2001.00009.x     Document Type: Article
Times cited : (37)

References (47)
  • 1
    • 0033812015 scopus 로고    scopus 로고
    • Postnatal handling alters the activation of stress-related neuronal circuitries
    • Abraham, I. & Kovacs, K. (2000) Postnatal handling alters the activation of stress-related neuronal circuitries. Eur J Neurosci 12, 3003-3014.
    • (2000) Eur J Neurosci , vol.12 , pp. 3003-3014
    • Abraham, I.1    Kovacs, K.2
  • 2
    • 0034623304 scopus 로고    scopus 로고
    • Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brain
    • Biebl, M., Cooper, C.M., Winkler, J. & Kuhn, H.G. (2000) Analysis of neurogenesis and programmed cell death reveals a self- renewing capacity in the adult rat brain. Neurosci Lett 291, 17-20.
    • (2000) Neurosci Lett , vol.291 , pp. 17-20
    • Biebl, M.1    Cooper, C.M.2    Winkler, J.3    Kuhn, H.G.4
  • 3
    • 0030167280 scopus 로고    scopus 로고
    • The effects of post-weaning environment, biological dam, and nursing dam on feeding neophobia, open field activity, and learning
    • Bors, D.A. & Forrin, B. (1996) The effects of post-weaning environment, biological dam, and nursing dam on feeding neophobia, open field activity, and learning. Can J Exp Psychol 50, 197-204.
    • (1996) Can J Exp Psychol , vol.50 , pp. 197-204
    • Bors, D.A.1    Forrin, B.2
  • 4
    • 0033205123 scopus 로고    scopus 로고
    • Effects of prenatal exposure to a mild chronic variable stress on body weight, preweaning mortality and rat behavior
    • Cabrera, R.J., Rodriguez-Echandia, E.L., Jatuff, A.S. & Foscolo, M. (1999) Effects of prenatal exposure to a mild chronic variable stress on body weight, preweaning mortality and rat behavior. Braz J Med Biol Res 32, 1229-1237.
    • (1999) Braz J Med Biol Res , vol.32 , pp. 1229-1237
    • Cabrera, R.J.1    Rodriguez-Echandia, E.L.2    Jatuff, A.S.3    Foscolo, M.4
  • 5
    • 0032574785 scopus 로고    scopus 로고
    • Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat
    • Caldji, C, Tannenbaum, B., Sharma, S., Francis, D., Plotsky, P. & Meaney, M.J. (1998) Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat. Proc Natl Acad Sci USA 95, 5335-5340.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5335-5340
    • Caldji, C.1    Tannenbaum, B.2    Sharma, S.3    Francis, D.4    Plotsky, P.5    Meaney, M.J.6
  • 6
    • 0028364703 scopus 로고
    • Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus
    • Cameron, H.A. & Gould, E. (1994) Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience 61, 203-209.
    • (1994) Neuroscience , vol.61 , pp. 203-209
    • Cameron, H.A.1    Gould, E.2
  • 7
    • 0033306418 scopus 로고    scopus 로고
    • Restoring production of hippocampal neurons in old age
    • Cameron, H.A. & McKay, R.D. (1999) Restoring production of hippocampal neurons in old age. Nat Neurosci 2, 894-897.
    • (1999) Nat Neurosci , vol.2 , pp. 894-897
    • Cameron, H.A.1    McKay, R.D.2
  • 8
    • 0023149179 scopus 로고
    • Transfer of effects from environmentally enriched and impoverished female rats to future offspring
    • Dell, P.A. & Rose, F.D. (1987) Transfer of effects from environmentally enriched and impoverished female rats to future offspring. Physiol Behav 39, 187-190.
    • (1987) Physiol Behav , vol.39 , pp. 187-190
    • Dell, P.A.1    Rose, F.D.2
  • 9
    • 0014145640 scopus 로고
    • Increased adrenocortical activity in the neonatal rat following handling
    • Denenberg, V.H., Brumaghim, J.T., Haltmeyer, G.C. & Zarrow, M.X. (1967) Increased adrenocortical activity in the neonatal rat following handling. Endocrinology 81, 1047-1052
    • (1967) Endocrinology , vol.81 , pp. 1047-1052
    • Denenberg, V.H.1    Brumaghim, J.T.2    Haltmeyer, G.C.3    Zarrow, M.X.4
  • 10
    • 0013980227 scopus 로고
    • Comparison of background stimulation and handling as forms of infantile stimulation
    • Denenberg, V.H., Schell, S.F, Karas, G.G. & Haltmeyer, G.C. (1966) Comparison of background stimulation and handling as forms of infantile stimulation. Psychol Rep 19, 943-948.
    • (1966) Psychol Rep , vol.19 , pp. 943-948
    • Denenberg, V.H.1    Schell, S.F.2    Karas, G.G.3    Haltmeyer, G.C.4
  • 11
    • 0016436874 scopus 로고
    • Direct contact with enriched environment is required to alter cerebral weights in rats
    • Ferchmin, P.A. & Bennett, E.L. (1975) Direct contact with enriched environment is required to alter cerebral weights in rats. J Comp Physiol Psychol 88, 360-367.
    • (1975) J Comp Physiol Psychol , vol.88 , pp. 360-367
    • Ferchmin, P.A.1    Bennett, E.L.2
  • 12
    • 0031425147 scopus 로고    scopus 로고
    • Neonatal handling and environmental enrichment effects on emotionality, novelty/reward seeking, and age-related cognitive and hippocampal impairments: Focus on the Roman rat lines
    • Fernandez-Teruel, A., Escorihuela, R.M., Castellano, B., Gonzalez, B. & Tobena, A (1997) Neonatal handling and environmental enrichment effects on emotionality, novelty/reward seeking, and age-related cognitive and hippocampal impairments: focus on the Roman rat lines. Behav Genet 27, 513-526
    • (1997) Behav Genet , vol.27 , pp. 513-526
    • Fernandez-Teruel, A.1    Escorihuela, R.M.2    Castellano, B.3    Gonzalez, B.4    Tobena, A.5
  • 13
    • 0033363319 scopus 로고    scopus 로고
    • Learning enhances adult neurogenesis in the hippoampal formation
    • Gould, E., Beylin, A., Tanapat, P., Reeves, A. & Shors, T.J. (1999) Learning enhances adult neurogenesis in the hippoampal formation. Nat Neurosci 2, 260-265
    • (1999) Nat Neurosci , vol.2 , pp. 260-265
    • Gould, E.1    Beylin, A.2    Tanapat, P.3    Reeves, A.4    Shors, T.J.5
  • 14
    • 0030992982 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation
    • Gould, E., McEwen, B.S., Tanapat, P., Galea, L.A.M. & Fuchs, E. (1997) Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci 17, 2492-2498.
    • (1997) J Neurosci , vol.17 , pp. 2492-2498
    • Gould, E.1    McEwen, B.S.2    Tanapat, P.3    Galea, L.A.M.4    Fuchs, E.5
  • 16
    • 13144265718 scopus 로고    scopus 로고
    • Environmental stimulation of 129/SvJ mice results in increased cell proliferation and neurogenesis in the adult dentate gyrus
    • Kempermann, G, Brandon, E.P. & Gage, F.H. (1998a) Environmental stimulation of 129/SvJ mice results in increased cell proliferation and neurogenesis in the adult dentate gyrus. Curr Biol 8, 939-942.
    • (1998) Curr Biol , vol.8 , pp. 939-942
    • Kempermann, G.1    Brandon, E.P.2    Gage, F.H.3
  • 17
    • 0032972245 scopus 로고    scopus 로고
    • Experience-dependent regulation of adult hippocampal neurogenesis: Effects of long-term stimulation and stimulus withdrawal
    • Kempermann, G. & Gage, F.H. (1999) Experience-dependent regulation of adult hippocampal neurogenesis: effects of long-term stimulation and stimulus withdrawal. Hippocampus 9, 321-332.
    • (1999) Hippocampus , vol.9 , pp. 321-332
    • Kempermann, G.1    Gage, F.H.2
  • 18
    • 0030937293 scopus 로고    scopus 로고
    • More hippocampal neurons in adult mice living in an enriched environment
    • Kempermann, G., Kuhn, H.G. & Gage, F.H. (1997a) More hippocampal neurons in adult mice living in an enriched environment. Nature 386, 493-495.
    • (1997) Nature , vol.386 , pp. 493-495
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 19
    • 0030987612 scopus 로고    scopus 로고
    • Genetic influence on neurogenesis in the dentate gyrus of adult mice
    • Kempermann, G., Kuhn, H.G. & Gage, F.H. (1997b) Genetic influence on neurogenesis in the dentate gyrus of adult mice. Proc Natl Acad Sci USA 94, 10409-10414.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10409-10414
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 20
    • 0032080116 scopus 로고    scopus 로고
    • Experience-induced neurogenesis in the senescent dentate gyrus
    • Kempermann, G., Kuhn, H.G. & Gage, F.H. (1998b) Experience-induced neurogenesis in the senescent dentate gyrus. J Neurosci 18, 3206-3212.
    • (1998) J Neurosci , vol.18 , pp. 3206-3212
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 21
    • 0018175227 scopus 로고
    • Selective Depression of serum growth hormone during maternal deprivation in rat pups
    • Kuhn, C.M., Butler, S.R. & Schanberg, S.M. (1978) Selective Depression of serum growth hormone during maternal deprivation in rat pups. Science 201, 1034-1036.
    • (1978) Science , vol.201 , pp. 1034-1036
    • Kuhn, C.M.1    Butler, S.R.2    Schanberg, S.M.3
  • 22
    • 0016251344 scopus 로고
    • The effects of neonatal tactile stimulation on adult emotional reactivity in BALB-c mice
    • Labarba, R.C., Fernandez, B., White, J.L. & Stewart, A. (1974) The effects of neonatal tactile stimulation on adult emotional reactivity in BALB-c mice. Dev Psychobiol 7, 393-398.
    • (1974) Dev Psychobiol , vol.7 , pp. 393-398
    • Labarba, R.C.1    Fernandez, B.2    White, J.L.3    Stewart, A.4
  • 23
    • 0034718603 scopus 로고    scopus 로고
    • Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus
    • Lemaire, V., Koehl, M., Le Moal, M. & Abrous, D.N. (2000) Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus. Proc Natl Acad Sci USA 97, 11032-11037.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 11032-11037
    • Lemaire, V.1    Koehl, M.2    Le Moal, M.3    Abrous, D.N.4
  • 24
    • 0000852663 scopus 로고
    • Plasma-free corticosteroid response to electric shock in rats stimulated in infancy
    • Levine, S. (1962) Plasma-free corticosteroid response to electric shock in rats stimulated in infancy. Science 135, 795-796.
    • (1962) Science , vol.135 , pp. 795-796
    • Levine, S.1
  • 25
    • 0031595180 scopus 로고    scopus 로고
    • Behavioural profiles of two Wistar rat lines selectively bred for high or low anxiety-related behaviour
    • Liebsch, G., Montkowski, A., Holsboer, F. & Landgraf, R. (1998) Behavioural profiles of two Wistar rat lines selectively bred for high or low anxiety-related behaviour. Behav Brain Res 94, 301-310
    • (1998) Behav Brain Res , vol.94 , pp. 301-310
    • Liebsch, G.1    Montkowski, A.2    Holsboer, F.3    Landgraf, R.4
  • 26
    • 0033952402 scopus 로고    scopus 로고
    • Influence of neonatal rearing conditions on stress-induced adrenocorticotropin responses and norepinepherine release in the hypothalamic paraventricular nucleus
    • Liu, D., Caldji, C, Sharma, S., Plotsky, P.M. & Meaney, M.J. (2000a) Influence of neonatal rearing conditions on stress-induced adrenocorticotropin responses and norepinepherine release in the hypothalamic paraventricular nucleus. J Neuroendocrinol 12, 5-12.
    • (2000) J Neuroendocrinol , vol.12 , pp. 5-12
    • Liu, D.1    Caldji, C.2    Sharma, S.3    Plotsky, P.M.4    Meaney, M.J.5
  • 27
    • 0033926720 scopus 로고    scopus 로고
    • Maternal care, hippocampal synaptogenesis and cognitive development in rats
    • Liu, D., Diorio, J., Day, J.C., Francis, D.D. & Meaney, M.J. (2000b) Maternal care, hippocampal synaptogenesis and cognitive development in rats. Nature Neurosci 3, 799-806.
    • (2000) Nature Neurosci , vol.3 , pp. 799-806
    • Liu, D.1    Diorio, J.2    Day, J.C.3    Francis, D.D.4    Meaney, M.J.5
  • 28
    • 0015145736 scopus 로고
    • The effects of environmental manipulation on the morphology of the neonate rat brain
    • Malkasian, D.R. & Diamond, M.C. (1971) The effects of environmental manipulation on the morphology of the neonate rat brain. Int J Neurosci 2, 161-169.
    • (1971) Int J Neurosci , vol.2 , pp. 161-169
    • Malkasian, D.R.1    Diamond, M.C.2
  • 29
    • 0026010865 scopus 로고
    • Postnatal handling attenuates certain neuroendocrine, anatomical, and cognitive dysfunctions associated with aging in female rats
    • Meaney, M.J., Aitken, D.H., Bhatnagar, S. & Sapolsky, R.M. (1991a) Postnatal handling attenuates certain neuroendocrine, anatomical, and cognitive dysfunctions associated with aging in female rats. Neurobiol Aging 12, 31-38
    • (1991) Neurobiol Aging , vol.12 , pp. 31-38
    • Meaney, M.J.1    Aitken, D.H.2    Bhatnagar, S.3    Sapolsky, R.M.4
  • 30
    • 0023877370 scopus 로고
    • Effect of neonatal handling on age-related impairments associated with the hippocampus
    • Meaney, M.J., Aitken, D.H., van Berkel, C., Bhatnagar, S. & Sapolsky, R.M. (1988) Effect of neonatal handling on age-related impairments associated with the hippocampus. Science 239, 766-768.
    • (1988) Science , vol.239 , pp. 766-768
    • Meaney, M.J.1    Aitken, D.H.2    Van Berkel, C.3    Bhatnagar, S.4    Sapolsky, R.M.5
  • 31
    • 0025833163 scopus 로고
    • The effects of neonatal handling on the development of the adrenocortical response to stress: Implications for neuropathology and cognitive deficits in later life
    • Meaney, M.J., Mitchell, J.B., Aitken, D.H., Bhatnagar, S., Bodnoff, S.R., Iny, L.J. & Sarrieau, A. (1991b) The effects of neonatal handling on the development of the adrenocortical response to stress: implications for neuropathology and cognitive deficits in later life. Psychoneuroendocrinology 16, 85-103.
    • (1991) Psychoneuroendocrinology , vol.16 , pp. 85-103
    • Meaney, M.J.1    Mitchell, J.B.2    Aitken, D.H.3    Bhatnagar, S.4    Bodnoff, S.R.5    Iny, L.J.6    Sarrieau, A.7
  • 32
    • 0033564083 scopus 로고    scopus 로고
    • Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory
    • Nilsson, M., Perflilieva, E., Johansson, U., Orwar, O. & Eriksson, P. (1999) Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory. J Neurobiol 39, 569-578.
    • (1999) J Neurobiol , vol.39 , pp. 569-578
    • Nilsson, M.1    Perflilieva, E.2    Johansson, U.3    Orwar, O.4    Eriksson, P.5
  • 33
    • 0029901232 scopus 로고    scopus 로고
    • Effects of preweaning sensorimotor stimulation on behavioral and neuronal development in motor and visual cortex of the rat
    • Pascual, R. & Figueroa, H. (1996) Effects of preweaning sensorimotor stimulation on behavioral and neuronal development in motor and visual cortex of the rat. Biol Neonate 69, 399-404.
    • (1996) Biol Neonate , vol.69 , pp. 399-404
    • Pascual, R.1    Figueroa, H.2
  • 34
    • 0342711263 scopus 로고    scopus 로고
    • Effects of neonatal stimulation on later cognitive function and hippocampal nerve growth factor
    • Pham, T., Soederstroem, S., Henriksson, B. & Mohammed, A. (1997) Effects of neonatal stimulation on later cognitive function and hippocampal nerve growth factor. Behav Brain Res 86, 113-120.
    • (1997) Behav Brain Res , vol.86 , pp. 113-120
    • Pham, T.1    Soederstroem, S.2    Henriksson, B.3    Mohammed, A.4
  • 36
    • 0014613209 scopus 로고
    • Effects of differential environments on brain weights and enzyme activities in gerbils, rats, and mice
    • Rosenzweig, M.R. & Bennett, E.L. (1969) Effects of differential environments on brain weights and enzyme activities in gerbils, rats, and mice. Dev Psychobiol 2, 87-95.
    • (1969) Dev Psychobiol , vol.2 , pp. 87-95
    • Rosenzweig, M.R.1    Bennett, E.L.2
  • 37
    • 0015454232 scopus 로고
    • The effects of preweaning handling and postweaning housing on behavior and resistence to deprivation induced stress in the rat
    • Schaefer, G. & Darbes, A. (1972) The effects of preweaning handling and postweaning housing on behavior and resistence to deprivation induced stress in the rat. Dev Psychobiol 5, 231-238
    • (1972) Dev Psychobiol , vol.5 , pp. 231-238
    • Schaefer, G.1    Darbes, A.2
  • 38
    • 0014950986 scopus 로고
    • Early experience effects upon cortical dendrites: A proposed model for development
    • Schapiro, S. & Vukovich, K.R. (1970) Early experience effects upon cortical dendrites: a proposed model for development. Science 167, 292-294.
    • (1970) Science , vol.167 , pp. 292-294
    • Schapiro, S.1    Vukovich, K.R.2
  • 39
    • 0345299174 scopus 로고    scopus 로고
    • High versus low reactivity to a novel environment: Behavioural, pharmacological and neurochemical assessments
    • Thiel, C.M., Muller, C.P., Huston, J.P. & Schwarting, R.K. (1999) High versus low reactivity to a novel environment: behavioural, pharmacological and neurochemical assessments. Neuroscience 93, 243-251.
    • (1999) Neuroscience , vol.93 , pp. 243-251
    • Thiel, C.M.1    Muller, C.P.2    Huston, J.P.3    Schwarting, R.K.4
  • 40
    • 0032816671 scopus 로고    scopus 로고
    • Long-term effects of prenatal stress and postnatal handling on age-related glucocorticoid secretion and cognitive performance: A longitudinal study in the rat
    • Vallée, M., Maccari, S., Dellu, F., Simon, H., Le Moal, M. & Mayo, W.(1999) Long-term effects of prenatal stress and postnatal handling on age-related glucocorticoid secretion and cognitive performance: a longitudinal study in the rat Eur J Neurosci 11, 2906-2916.
    • (1999) Eur J Neurosci , vol.11 , pp. 2906-2916
    • Vallée, M.1    Maccari, S.2    Dellu, F.3    Simon, H.4    Le Moal, M.5    Mayo, W.6
  • 41
    • 0033539607 scopus 로고    scopus 로고
    • Running enhances neurogenesis, learning and long-term potentiation in mice
    • Van Praag, H., Christie, B.R., Sejnowski, T.J. & Gage, F.H. (1999a) Running enhances neurogenesis, learning and long-term potentiation in mice. Proc Natl Acad Sci USA 96, 13427-13431.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13427-13431
    • Van Praag, H.1    Christie, B.R.2    Sejnowski, T.J.3    Gage, F.H.4
  • 42
    • 0033360314 scopus 로고    scopus 로고
    • Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
    • Van Praag, H., Kempermann, G. & Gage, F.H. (1999b) Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci 2, 266-270.
    • (1999) Nat Neurosci , vol.2 , pp. 266-270
    • Van Praag, H.1    Kempermann, G.2    Gage, F.H.3
  • 43
    • 0024436033 scopus 로고
    • Effects of preweaning environmental enrichment on basilar dendrites of pyramidal neurons in occipital cortex: A Golgi study
    • Venable, N., Fernandez, V., Diaz, E. & Pinto-Hamuy, T. (1989) Effects of preweaning environmental enrichment on basilar dendrites of pyramidal neurons in occipital cortex: a Golgi study. Brain Res Dev Brain Res 49, 140-144.
    • (1989) Brain Res Dev Brain Res , vol.49 , pp. 140-144
    • Venable, N.1    Fernandez, V.2    Diaz, E.3    Pinto-Hamuy, T.4
  • 44
    • 0027424040 scopus 로고
    • Effects of early experience on behavior and immune response in the rat
    • Von Hoersten, S., Dimitrijevic, M., Markovic, B. & Jankovic, B. (1993) Effects of early experience on behavior and immune response in the rat. Physiol Behav 54, 931-940.
    • (1993) Physiol Behav , vol.54 , pp. 931-940
    • Von Hoersten, S.1    Dimitrijevic, M.2    Markovic, B.3    Jankovic, B.4
  • 45
    • 0024268109 scopus 로고
    • Three-dimensional counting: An accurate and direct method to estimate numbers of cells in sectioned material
    • Williams, R.W. & Rakic, P. (1988) Three-dimensional counting: an accurate and direct method to estimate numbers of cells in sectioned material. J Comp Neurol 278, 344-352.
    • (1988) J Comp Neurol , vol.278 , pp. 344-352
    • Williams, R.W.1    Rakic, P.2
  • 46
    • 0032584142 scopus 로고    scopus 로고
    • Stress facilitates classical conditioning in males, but impairs classical conditioning in females through activational effects of ovarian hormones
    • Wood, G.E. & Shors, T.J. (1998) Stress facilitates classical conditioning in males, but impairs classical conditioning in females through activational effects of ovarian hormones. Proc Natl Acad Sci USA 95, 4066-4071.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4066-4071
    • Wood, G.E.1    Shors, T.J.2
  • 47
    • 0032957382 scopus 로고    scopus 로고
    • Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
    • Young, D., Lawlor, P.A., Leone, P., Dragunow, M. & During, M.J. (1999) Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nat Med 5, 448-453.
    • (1999) Nat Med , vol.5 , pp. 448-453
    • Young, D.1    Lawlor, P.A.2    Leone, P.3    Dragunow, M.4    During, M.J.5


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