메뉴 건너뛰기




Volumn 603, Issue 1, 2000, Pages 2-5

Microwave-mediated palladium-catalyzed asymmetric allylic alkylation; an example of highly selective fast chemistry

Author keywords

Allylic alkylation; Enantioselectivity; Fast chemistry; Microwave chemistry; Palladium catalysis

Indexed keywords


EID: 0001820449     PISSN: 0022328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-328X(00)00023-1     Document Type: Article
Times cited : (30)

References (29)
  • 9
    • 85037469088 scopus 로고    scopus 로고
    • (c) G. Whittaker, http://www.ed.ac.uk/ ∼ ah05/basicintro.html.
    • Whittaker, G.1
  • 25
    • 85037447589 scopus 로고    scopus 로고
    • note
    • The omission of the potassium acetate, reported to be needed for decomposition of BSA, did not alter the outcome of the alkylation after conventional heating, nor after microwave irradiation at power input up to 120 W. At a microwave power of 500 W, the addition of very small amounts of potassium acetate allowed for full conversion using 3a as ligand. An 85% yield was encountered in absence of potassium acetate under otherwise identical conditions. No effect of potassium acetate was observed when using 3b as ligand. The ee values were not affected by the addition of potassium acetate nor were the temperature profiles.
  • 26
    • 0027178644 scopus 로고
    • For a discussion on the possible impact of high heating rates on selectivity in organic chemistry see: D. Stuerga, K. Gonon, M. Lallenant, Tetrahedron, 49 (1993) 6229.
    • (1993) Tetrahedron , vol.49 , pp. 6229
    • Stuerga, D.1    Gonon, K.2    Lallenant, M.3
  • 27
    • 85037468688 scopus 로고    scopus 로고
    • The Microwell 10™ has a power efficiency of ∼ 50% (meaning 250 W power input to the sample at 500 W applied power)
    • The Microwell 10™ has a power efficiency of ∼ 50% (meaning 250 W power input to the sample at 500 W applied power).
  • 29
    • 85037462179 scopus 로고    scopus 로고
    • The catalyst solution could be stored at -18°C for several weeks without loss of catalytic activity. At ambient temperature the catalyst solution slowly decomposed
    • The catalyst solution could be stored at -18°C for several weeks without loss of catalytic activity. At ambient temperature the catalyst solution slowly decomposed.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.