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Volumn 58, Issue 11, 2000, Pages 1095-1099

Memory of chirality: Alkylation of α-amino acid derivatives

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Indexed keywords


EID: 0001700715     PISSN: 00379980     EISSN: None     Source Type: Journal    
DOI: 10.5059/yukigoseikyokaishi.58.1095     Document Type: Article
Times cited : (14)

References (31)
  • 9
    • 0033531681 scopus 로고    scopus 로고
    • Recently, excellent catalytic methods for asymmetric synthesis of α, α-disubtituted α-amino acid derivatives have been developed; for examples, see: (a) Kuwano, R. Ito, Y. J. Am. Chem. Soc. 1999, 121, 3236.
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 3236
    • Kuwano, R.1    Ito, Y.2
  • 16
    • 85046527639 scopus 로고    scopus 로고
    • note
    • 2S, 2) 1 M NaOH, 3) 47% aq HBr.
  • 18
    • 85046528192 scopus 로고    scopus 로고
    • note
    • ≃ of the restricted bond rotation is nearly zero.
  • 19
    • 19444385157 scopus 로고    scopus 로고
    • note
    • The Z- and E-enolate intermediates should afford α-methylated products of the same absolute configuration, since the 2 : 1 geometric mixture of enolates gave the product of 81% ee in 96% yield (Table 3, entry 1).
  • 20
    • 19444378167 scopus 로고    scopus 로고
    • note
    • The 2,3-dihydroxazole ring in the potassium enolate G is supposed to be nearly planar.
  • 21
    • 0043162336 scopus 로고
    • The most stable conformation H of 9d was generated by MCMM search with MM3* force field using MacroModel V6.0: (a) Chang, G.; Guida, W. C.; Still, W. C. J. Am Chem. Soc. 1989, 111, 4379.
    • (1989) J. Am Chem. Soc. , vol.111 , pp. 4379
    • Chang, G.1    Guida, W.C.2    Still, W.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.