DNA damage via intercalation of copper complexes and activation by ascorbate and peroxides: Direct EPR evidence for hydroxyl radical formation and reaction

Journal of the Chemical Society. Perkin Transactions 2

Volumn , Issue 9, 1999, Pages 1891-1895

  Gilbert, Bruce C ^a   Silvester, Stephen ^a   Walton, Paul H ^a   Whitwood, Adrian C ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001639818     PISSN: 03009580     EISSN: None     Source Type: Journal    
DOI: 10.1039/a903403j     Document Type: Article

References (25)

1. S. E. Bryan, D. L. Vizard, D. A. Beary, R. A. LaBiche and K. J. Hardy, Nucleic Acids Res., 1981, 9, 5811.
2. C. D. Lewis and U. Laemmli, Cell. 1982, 29, 171.
3. S. Hu, P. Furst and D. Hamer, New Biol., 1990, 2, 544.
4. N. L. Brown, B. T. O. Lee and S. Silver, Met. Ions Biol. Syst., 1995, 30, 405.
5. C. J. Reed and K. T. Douglas, Biochem. J., 1991, 275, 601.
6. D. S. Sigman, R. Landgraf, D. M. Perrin and L. Pearson, Met. Ions Biol. Syst., 1996, 30, 485.
7. L. Milne, P. Nicotera, S. Orrenius and M. J. Burkitt, Arch. Biochem. Biophys., 1993, 304, 102.
8. W. E. Anthroline, R. Byrnes and D. H. Petering, Copper complexes as Drugs, in Handbook of Metal Ligand Interactions in Biological Fluids; Bioinorganic Chemistry, ed. G. Berthon, Dekker, New York, 1995, vol. 2, p. 1024.
9. J.-I. Ueda, M. Takai, Y. Shimazu and T. Ozawa, Arch. Biochem. Biophys., 1998, 357, 231.
10. G. Scrivens, B. C. Gilbert and T. C. P. Lee, J. Chem. Soc., Perkin Trans. 2, 1995, 955.
11. B. C. Gilbert, S. Silvester and P. H. Walton, J. Chem. Soc., Perkin Trans. 2, 1999, 1115.
12. B. C. Gilbert and S. Silvester, Nukleonika, 1997, 42, 307.
13. B. C. Gilbert, G. Harrington, G. Scrivens and S. Silvester, EPR studies of Fenton-type reactions in copper-peroxide systems, in Free Radicals in Biology and the Environment 49, ed. F. Minisci, NATO ASI Series, Kluwer Academic Publishers, Dordrecht, 1997.
14. J. Z. Pedersen, C. Steinkühler, U. Weser and G. Rotilo, BioMetals, 1996, 9, 3.
15. F. J. Davis, B. C. Gilbert, R. O. C. Norman and M. C. R. Symons, J. Chem. Soc.,Perkin Trans. 2, 1983, 1763.
16. F. E. Mabbs and D. Collison, Electron paramagnetic resonance of d transition metal compounds, Elsevier, London, 1992.
17. W. A. Prütz, J. Biochem. Biophys. Methods, 1996, 32, 125.
18. M. Hirai, K. Shinozuka, H. Sawai and S. Ogawa, Bull. Chem. Soc. Jpn., 1994, 67, 1147
19. B. A. Goodman and J. B. Raynor, Adv. Inorg. Chem. Radiochem., 1977, 13, 136.
20. H. R. Gersmann and J. D. Swalen, J. Chem. Phys., 1962, 36, 3221.
21. J. Foley, S. Tyagi and B. J. Hathaway, J. Chem. Soc., Dalton Trans., 1984, 1.
22. S. Siddiqui and R. E. Shepherd, Inorg. Chem., 1986, 25, 3869.
23. I. Marov, V. K. Belyaeva, E. B. Smirnova and I. F. Dolmanova, Inorg. Chem., 1978, 17, 1667.
24. S. Mahadevan and M. Palaniandavar, Inorg. Chem., 1998, 37, 3927.
25. R. T. Pflaum and W. W. Brandt, J. Am. Chem. Soc., 1955, 77, 2019.