Detection of apoptosis and phagocytosis in vitro in C6 rat glioma cells treated with tiazofurin

Apoptosis

Volumn 3, Issue 5, 1998, Pages 345-352

  Piperski, V ^a   Vracar M ^a   Jokanovic M ^a   Stukalov, P ^b   Rakic L ^a  

^a ICN Yugoslavia   (Yugoslavia)

^b CLINICAL CENTER OF SERBIA   (Serbia)

Author keywords

Apoptosis; Phagocytosis; Rat glioma; Tiazofurin

Indexed keywords

EID: 0001564148     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009677021374     Document Type: Article

References (27)

1. Robins RK. Nucleoside and nucleotide inhibitors of inosine monophosphate (IMP) dehydrogenase as potential antitumor inhibitors. Nucleosides Nucleotides 1982; 1: 35-44.
2. Jayaram HN, Pillwein K, Weber G. Increased nucleoside concentrations in tumors as markers of tiazofurin action. Nucleosides Nucleotides 1986; 5: 503-509.
3. Weber G, Prajda N, Abonyi M, Look KY, Tricot G. Tiazofurin: molecular and clinical action. Anticancer Res 1996; 6: 3313-3322.
4. Tricot G, Jayaram HN, Weber G, Hoffman R. Tiazofurin: biological effects and clinical uses. Int J Cell Cloning 1990; 8: 161-170.
5. Olah E, Csokai B, Prajda N, Kote-Jarai Z, Albert Yeh Y, Weber G. Molecular mechanism in the antiproliferative action of taxol and tiazofurin. Anticancer Res 1996; 16: 2469-2478.
6. Pillwein K, Schuchter K, Ressmann G, et al. Cytotoxicity, differentiating activity and metabolism of tiazofurin in human neuroblastoma cells. Int J Cancer 1993; 55: 92-95.
7. Kiguchi K, Collart FR, Henning-Chubb C, Huberman, E. Induction of cell diferentiation in melanoma cells by inhibitors of IMP-dehydrogenase: altered patterns of IMP-dehydrogenase expression and activity. Cell Growth Differ 1990; 1: 259-270.
8. Vitale M, Zamai L, Falcieri E, et al. IMP dehydrogenase inhibitor, tiazofurin, iduces apoptosis in K562 human erythroleukemia cells. Cytometry 1997; 30: 61-66.
9. Pillwen K, Chiba P, Knoflach A, et al. Purine metabolism of human glioblastoma in vivo. Cancer Res 1990; 50: 1576-1579.
10. Benda P, Lightbody J, Sato G, Levine L, Sweet W. Differentiated rat glial cell strain in tissue culture. Science 1969; 161: 370-371.
11. Jovanovic S, Redzic Z, Markovic I, Rakic L. Transport of tiazofurin, a C6 synthetic analogue, through the rat blood-brain tumor barrier. Proc 11th Cong Neurolog Surg 1763-1766, 1997.
12. Yoshimura S, Sakai H, Takenaka K, et al. Intracellular signal transduction during ceramide-induced apoptosis in cultured glioma cells. Proc 11th Int Cong of Neurolog Surg 1745-1749, 1997.
13. Yasugi E, Yokoyama Y, Seyama Y, Kano K, Hayashi Y, Oshima M. Dolichyl phosphate, a potent inducer of apoptosis in rat glioma C6 cells. Biochem Biophys Res Com 1995; 216: 848-853.
14. Baudet C, Chevalier G, Chassevent A, et al. 1,25-Dihydroxyvitamin D3 induces programmed cell death in a rat glioma cell line. J Neurosci Res 1996; 46: 540-550.
15. Yin D, Kondo S, Barnett GH, Morimura T, Takeuchi J. Tumor necrosis factor-α induces p53-dependent apoptosis in rat glioma cells. Neurosurgery 1995; 37: 758-763.
16. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493-501.
17. Kerr JFR, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-257.
18. Willie AH, Kerr JFR, Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 1980; 68: 251-306.
19. Harmon BV, Takano YS, Winterford CM, Potten CS. Cell death induced by vincristine in the intestinal crypts of mice and in a human Burkitt's lymphoma cell line. Cell Prolif 1992; 25: 523-526.
20. Savill J. Phagocyte recognition of apoptotic cells. Biochem Soc Transact 1996; 24: 1065-1069.
21. Cohen GM, Sun X-M, Snowden RT, Dinsdale D, Slilleter DN. Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem J 1992; 286: 331-334.
22. Parandoosh Z, Rubalcava B, Matsumoto SS, Jolley WB, Robins RK. Changes in diacylglycerol and cyclic GMP during the differentiation of human myeloid leukemia K562 cells. Life Sci 1990; 46: 315-320.
23. Buznikov GA, Malchenko LA, Zvezdina ND, et al. Effects of tiazofurin on devdopment of sea urchin embryos and larvae. Ontogenez (Russian J Dev Biol) 1996; 27: 62-69.
24. Vaux DL, Strasser A The molecular biology of apoptosis. Proc Natl Acad Sci USA 1996; 93: 2239-2244.
25. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241-251.
26. Gotz C, Montenarh M. p53 and its implication in apoptosis (Review). Int J Oncol 1995; 6: 1129-1135.
27. Olah E, Kote Z, Natsumeda Y, et al. Down-regulation of c-myc and c-Ha-ras gene expression by tiazofurin in rat hepatoma cells. Cancer Biochem Biophys 1990; 11: 107-117.