A rapid screen of active site mutants in glycinamide ribonucleotide transformylase

Biochemistry

Volumn 35, Issue 27, 1996, Pages 8855-8862

  Warren, Mark S ^a   Marolewski, Ariane E ^a   Benkovic, Stephen J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; AMINO ACID; ASPARAGINE; ASPARTIC ACID; FOLINIC ACID; HISTIDINE; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; PROTON; RIBONUCLEOTIDE; SERINE; WATER;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE; MUTANT; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ACYLTRANSFERASES; BINDING SITES; CATALYSIS; ESCHERICHIA COLI; GENETIC COMPLEMENTATION TEST; HYDROGEN BONDING; HYDROXYMETHYL AND FORMYL TRANSFERASES; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; PROTEIN ENGINEERING; SELECTION (GENETICS); SEQUENCE ANALYSIS, DNA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030016226     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9528715     Document Type: Article

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