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Cho Sung-Baek, Miyaji F, Kokubo T, Nakanishi K, Soga N, Nakamura T. Apatite-forming ability of silicate ion dissolved from silica gels. J Biomedical Mater Res. 32:1996;375-381 Shows the importance of soluble silica on apatite film formation, relevant to biological behaviour (see reference [6] and Figures 1 and 2).
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Kim H-M, Miyaji F, Kokubo T, Nakamura T. Preparation of bioactive Ti and its alloys via simple chemical surface treatment. J Biomedical Mater Res. 32:1996;409-417 This simple chemical process may solve the problem of interfacial stability of hydroxyapatite coatings.
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2 gel-glasses with large compositional ranges behave as Class A bioactive materials with in vivo bone response similar to melt derived bioactive glass
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2 gel-glasses with large compositional ranges behave as Class A bioactive materials with in vivo bone response similar to melt derived bioactive glass.
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Transactions of the 23rd Annual Meeting of the Society for Biomaterials
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Society for Biomaterials, New Orleans, La, This is the first paper to show that mechanical properties of bone produced by osteoproduction of bioactive gel glasses are equivalent to bioactive melt glasses
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Hoellrich RG, Chamberland DL, Stokes KE, McLoughlin SW, Wheeler DL. In vivo evaluation of sol-gel bioglass. Part II: mechanical compression strength at 4 weeks. Transactions of the 23rd Annual Meeting of the Society for Biomaterials. 1997;Society for Biomaterials, New Orleans, La, This is the first paper to show that mechanical properties of bone produced by osteoproduction of bioactive gel glasses are equivalent to bioactive melt glasses.
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Transactions of the 23rd Annual Meeting of the Society for Biomaterials
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Hoellrich, R.G.1
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Osteogenic differentiation of culture marrow stromal stern cells on the surface of bioactive glass ceramics
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This paper is the latest in a series to identify the biochemical sequences involved in formation of new bone on bioactive surfaces. It identifies the mechanisms for reaction stages 8 and 9 in Figure 1 that is, a bioactive surface, promotes osteoblast differentiation and the promotion is enhanced by formation of a biological apatite layer.
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Ohgushi H, Dohi Y, Yoshikawa T, Tamai S, Tabata S, Okunaga K, Shibuya T. Osteogenic differentiation of culture marrow stromal stern cells on the surface of bioactive glass ceramics. J Biomedical Mater Res. 32:1996;341-348 This paper is the latest in a series to identify the biochemical sequences involved in formation of new bone on bioactive surfaces. It identifies the mechanisms for reaction stages 8 and 9 in Figure 1 that is, a bioactive surface, promotes osteoblast differentiation and the promotion is enhanced by formation of a biological apatite layer.
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The kinetics of adsorption and desorption of proteins and retention of protein conformation from bioactive gels are established here.
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Roux C, Livage J. Antibody-antigen reactions in porous sol-gel matrices. J Sol-Gel Sci Technol. 8:1997;663-666 Antibodies from human sera can diffuse through the pores of a sol-gel matrix and react specifically with immobilised antigens with biological activity equivalent to antigen solutions.
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Pope Edward JA. Bioartificial organs I: silica gel encapsulated pancreatic islets for the treatment of diabetes mellitus. J Sol-Gel Sci Technol. 8:1997;635-639 Maintenance of biological function of living cell colonies is the key to a new generation of artificial organs. This paper shows it is feasible using sol-gel matrices.
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Abe Y, Watanabe M, Nogami M. Phosphorous Research Bulletin. 6:1996;1-356 83 papers including many on the processing, characterisation, computer modeling and in vitro and in vivo behaviour of phosphorous-containing materials. Many Japanese papers not usually available in English.
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