Tuning the free-energy landscape of a WW domain by temperature, mutation, and truncation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 7, 2003, Pages 3948-3953

  Nguyen, Houbi ^a   Jäger, Marcus ^b,c   Moretto, Alessandro ^b   Gruebele, Martin ^a   Kelly, Jeffery W ^b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

sheet; strand; Protien folding mechanism

Indexed keywords

BINDING PROTEIN; FORMIN BINDING PROTEIN 28; TRYPTOPHAN; UNCLASSIFIED DRUG; CARRIER PROTEIN; FORMIN BINDING PROTEIN 28, HUMAN; RECOMBINANT PROTEIN;

ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; ENERGY; KINETICS; LASER; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; SIMULATION; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; GENE DELETION; GENETICS; MOLECULAR CLONING; MOLECULAR GENETICS; MUTAGENESIS; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN SECONDARY STRUCTURE; THERMODYNAMICS;

MUS;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CLONING, MOLECULAR; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SEQUENCE DELETION; THERMODYNAMICS;

EID: 0001071357     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0538054100     Document Type: Article

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