BINOL-Ti-catalyzed synthesis of tertiary homoallylic alcohols: The first catalytic asymmetric allylation of ketones

Organic Letters

Volumn 1, Issue 7, 1999, Pages 1061-1063

  Casolari, Sonia ^a   D'Addario, Daniela ^a   Tagliavini, Emilio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

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[No Author keywords available]

Indexed keywords

EID: 0000946629     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol990858x     Document Type: Article

References (20)

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17. 2 affording propene, tributyltin chloride, and the active BINOL-Ti catalyst. The real nature of such catalyst is under investigation by our group.
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20. 4, concentrated, and purified by flash cromatography to afford 5a in 77% yield and 65% ee. For the reactions promoted by Cat(B), the same procedure was applied using tetraallyltin (3b) (0.048 mL, 0.2 mmol) instead of allyltributyltin.