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Volumn 2, Issue 5, 1997, Pages 442-454

Expression of Bax, Bcl-2, Waf-1, and PCNA gene products in an immortalized human endothelial cell line undergoing p53-mediated apoptosis

Author keywords

Apoptosis; Endothelial; p53

Indexed keywords


EID: 0000534848     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026418010549     Document Type: Article
Times cited : (7)

References (47)
  • 1
    • 0026093164 scopus 로고
    • Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein
    • Martinez J, Georgoff I, Martinez J, Levine AJ. Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Develop 1991; 5: 151-159.
    • (1991) Genes Develop , vol.5 , pp. 151-159
    • Martinez, J.1    Georgoff, I.2    Martinez, J.3    Levine, A.J.4
  • 2
    • 0025086953 scopus 로고
    • p53 functions as a cell cycle control protein in osteosarcomas
    • Diller I, Kassel J, Nelson GE, et al. p53 functions as a cell cycle control protein in osteosarcomas. Mol Cell Biol 1990; 11: 5772-5781.
    • (1990) Mol Cell Biol , vol.11 , pp. 5772-5781
    • Diller, I.1    Kassel, J.2    Nelson, G.E.3
  • 4
    • 0027452415 scopus 로고
    • Wild-type p53 functions as a control protein in the differentiation pathway of the B-cell lineage
    • Alonigrinstein R, Zanbar I, Alboum I, Goldfinger N, Rotter V. Wild-type p53 functions as a control protein in the differentiation pathway of the B-cell lineage. Oncogene 1993; 8: 3297-3305.
    • (1993) Oncogene , vol.8 , pp. 3297-3305
    • Alonigrinstein, R.1    Zanbar, I.2    Alboum, I.3    Goldfinger, N.4    Rotter, V.5
  • 5
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Yin Y, Tainsky MA, Bischoff FZ, Strong LC, Wahl GM. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 1992; 70: 937-948.
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.C.4    Wahl, G.M.5
  • 6
    • 0026801062 scopus 로고
    • Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
    • Livingstone SR, White A, Sprouse J, Livanos E, Jacks T, Tisty TD. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 1992; 70: 923-935.
    • (1992) Cell , vol.70 , pp. 923-935
    • Livingstone, S.R.1    White, A.2    Sprouse, J.3    Livanos, E.4    Jacks, T.5    Tisty, T.D.6
  • 7
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • Dameron KM, Volpert OV, Tainsky MA, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 1994; 265: 1582-1584.
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 9
    • 0027536951 scopus 로고
    • p53-mediated cell death: Relationship to cell cycle control
    • Yonish-Rouach E, Grunwald D, Wilder S, et al. p53-mediated cell death: relationship to cell cycle control. Mol Cell Biol 1993; 13: 1415-1423.
    • (1993) Mol Cell Biol , vol.13 , pp. 1415-1423
    • Yonish-Rouach, E.1    Grunwald, D.2    Wilder, S.3
  • 10
    • 0027251720 scopus 로고
    • Wild-type p53 mediates apoptosis through E1A, which is inhibited by E1B
    • Debbas M, White E. Wild-type p53 mediates apoptosis through E1A, which is inhibited by E1B. Genes Develop 1993; 7: 546-554.
    • (1993) Genes Develop , vol.7 , pp. 546-554
    • Debbas, M.1    White, E.2
  • 11
    • 0027258466 scopus 로고
    • Thymocyte apoptosis induced by p53-dependent and independent pathways
    • Clarke AR, Purdie CA, Harrison DJ, et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 1993; 362: 849-852.
    • (1993) Nature , vol.362 , pp. 849-852
    • Clarke, A.R.1    Purdie, C.A.2    Harrison, D.J.3
  • 12
    • 0028294898 scopus 로고
    • Downregulation of wild-type p53 actively interferes with apoptosis of IL-3 dependent hematopoietic cells following IL-3 withdrawal
    • Gottlieb E, Haffner R, Von Ruden T, Wagner EF, Oren M. Downregulation of wild-type p53 actively interferes with apoptosis of IL-3 dependent hematopoietic cells following IL-3 withdrawal. EMBO J 1994; 13: 1368-1374.
    • (1994) EMBO J , vol.13 , pp. 1368-1374
    • Gottlieb, E.1    Haffner, R.2    Von Ruden, T.3    Wagner, E.F.4    Oren, M.5
  • 13
    • 0028047723 scopus 로고
    • The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
    • Merritt AJ, Potten CS, Kemp CJ, et al. The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res 1994; 54: 614-617.
    • (1994) Cancer Res , vol.54 , pp. 614-617
    • Merritt, A.J.1    Potten, C.S.2    Kemp, C.J.3
  • 14
    • 0027109075 scopus 로고
    • p53, guardian of the human genome
    • Lane DP. p53, guardian of the human genome. Nature 1992; 358: 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 15
  • 16
    • 0027298576 scopus 로고
    • Induction of cellular p53 activity by DNA-damaging agents and growth arrest
    • Zhan Z, Carrier F, Fornac AJ. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol Cell Biol 1993; 13: 4242-4250.
    • (1993) Mol Cell Biol , vol.13 , pp. 4242-4250
    • Zhan, Z.1    Carrier, F.2    Fornac, A.J.3
  • 18
    • 0029985445 scopus 로고    scopus 로고
    • Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells
    • Anthoney DA, McIlwrath AJ, Gallagher WM, Edlin AR, Brown R. Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells. Cancer Res 1996; 56: 1374-1381.
    • (1996) Cancer Res , vol.56 , pp. 1374-1381
    • Anthoney, D.A.1    McIlwrath, A.J.2    Gallagher, W.M.3    Edlin, A.R.4    Brown, R.5
  • 19
    • 8944263468 scopus 로고    scopus 로고
    • Association between cisplatin resistance and mutation of the p53 gene and reduced bax expression in ovarian carcinoma cell systems
    • Perego P, Giarola M, Righetti SC, et al. Association between cisplatin resistance and mutation of the p53 gene and reduced bax expression in ovarian carcinoma cell systems. Cancer Res 1996; 56: 556-562.
    • (1996) Cancer Res , vol.56 , pp. 556-562
    • Perego, P.1    Giarola, M.2    Righetti, S.C.3
  • 20
    • 0029555339 scopus 로고
    • Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53
    • Gjerset RA, Turla ST, Sobol RE, et al. Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53. Mol Carcinogen 1995; 14: 275-285.
    • (1995) Mol Carcinogen , vol.14 , pp. 275-285
    • Gjerset, R.A.1    Turla, S.T.2    Sobol, R.E.3
  • 21
    • 0027931008 scopus 로고
    • Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity
    • McIlwrath AJ, Vasey PA, Ross GM, Brown R. Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity. Cancer Res 1994; 54: 3718-3722.
    • (1994) Cancer Res , vol.54 , pp. 3718-3722
    • McIlwrath, A.J.1    Vasey, P.A.2    Ross, G.M.3    Brown, R.4
  • 22
    • 0028884525 scopus 로고
    • Cancer therapy and p53
    • Lowe SW. Cancer therapy and p53. Curr Opin Oncol 1995; 7: 547-553.
    • (1995) Curr Opin Oncol , vol.7 , pp. 547-553
    • Lowe, S.W.1
  • 23
    • 0025024469 scopus 로고
    • Presence of a potent transcription activating sequence in the p53 protein
    • Fields S, Jang SK. Presence of a potent transcription activating sequence in the p53 protein. Science 1990; 249: 1046-1048.
    • (1990) Science , vol.249 , pp. 1046-1048
    • Fields, S.1    Jang, S.K.2
  • 24
    • 0025193635 scopus 로고
    • Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene
    • Raycroft L, Wu H, Lozano G. Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene. Science 1990; 249: 1049-1051.
    • (1990) Science , vol.249 , pp. 1049-1051
    • Raycroft, L.1    Wu, H.2    Lozano, G.3
  • 25
    • 0026650531 scopus 로고
    • A transcriptionally active DNA-binding site for human p53 protein complexes
    • Funk WD, Pak DJ, Karas RH, Wright WE, Shay JW. A transcriptionally active DNA-binding site for human p53 protein complexes. Mol Cell Biol 1992; 12: 2866-2871.
    • (1992) Mol Cell Biol , vol.12 , pp. 2866-2871
    • Funk, W.D.1    Pak, D.J.2    Karas, R.H.3    Wright, W.E.4    Shay, J.W.5
  • 26
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • El-Deiry WS, Tokino T, Velculescu VE, at al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75: 817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 27
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of Gi cyclin-dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of Gi cyclin-dependent kinases. Cell 1993; 75: 805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 28
    • 0029063745 scopus 로고
    • Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1
    • Luo Y, Hurwitz J, Massague J. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Nature 1995; 375: 159-161.
    • (1995) Nature , vol.375 , pp. 159-161
    • Luo, Y.1    Hurwitz, J.2    Massague, J.3
  • 29
    • 0026496885 scopus 로고
    • A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
    • Kastan MB, Zhan Q, El-Deiry WS, et al. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 1992; 71: 587-597.
    • (1992) Cell , vol.71 , pp. 587-597
    • Kastan, M.B.1    Zhan, Q.2    El-Deiry, W.S.3
  • 30
    • 0028569767 scopus 로고
    • Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen
    • Smith ML, Chen IT, Zhan Q, et al. Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Science 1994; 266: 1376-1380.
    • (1994) Science , vol.266 , pp. 1376-1380
    • Smith, M.L.1    Chen, I.T.2    Zhan, Q.3
  • 31
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Myashita TS, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995; 80: 293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Myashita, T.S.1    Reed, J.C.2
  • 32
    • 0028292480 scopus 로고
    • Identification of a p53-dependent negative response element in the bcl-2 gene
    • Miyashita TS, Harigari M, Hanada M, Reed JC. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res 1994; 54: 3131-3135.
    • (1994) Cancer Res , vol.54 , pp. 3131-3135
    • Miyashita, T.S.1    Harigari, M.2    Hanada, M.3    Reed, J.C.4
  • 33
    • 0028864667 scopus 로고
    • Induction of the growth inhibitor IGF-binding protein 3 by p53
    • Buckbinder L, Talbott R, Velasco-Miguel S, et al. Induction of the growth inhibitor IGF-binding protein 3 by p53. Nature 1995; 377: 646-649.
    • (1995) Nature , vol.377 , pp. 646-649
    • Buckbinder, L.1    Talbott, R.2    Velasco-Miguel, S.3
  • 35
    • 0027138498 scopus 로고
    • Generation and identification of recombinant adenovirus by liposome-mediated transfection and PCR analysis
    • Zhang W-W, Fang X, Branch CD, Mazur W, French BA, Roth JA. Generation and identification of recombinant adenovirus by liposome-mediated transfection and PCR analysis. Biotechiniques 1993; 15: 868-872.
    • (1993) Biotechiniques , vol.15 , pp. 868-872
    • Zhang, W.-W.1    Fang, X.2    Branch, C.D.3    Mazur, W.4    French, B.A.5    Roth, J.A.6
  • 36
    • 0028816815 scopus 로고
    • Cell type-specific regulation of p53 expression in non-small cell lung carcinoma cells
    • Maxwell SA, Zhang W-W. Cell type-specific regulation of p53 expression in non-small cell lung carcinoma cells. Oncol Repts 1995; 2: 81-87.
    • (1995) Oncol Repts , vol.2 , pp. 81-87
    • Maxwell, S.A.1    Zhang, W.-W.2
  • 39
    • 0028868432 scopus 로고
    • Wild-type human p53 transactivates the human proliferating cell nuclear antigen promoter
    • Shivakumar CV, Brown DR, Deb S, Deb SP. Wild-type human p53 transactivates the human proliferating cell nuclear antigen promoter. Mol Cell Biol 1995; 15: 6785-6793.
    • (1995) Mol Cell Biol , vol.15 , pp. 6785-6793
    • Shivakumar, C.V.1    Brown, D.R.2    Deb, S.3    Deb, S.P.4
  • 40
    • 0030034524 scopus 로고    scopus 로고
    • Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53
    • Morris GF, Bischoff JR, Mathews MB. Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53. Proc Natl Acad Sci USA 1996; 93: 895-899.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 895-899
    • Morris, G.F.1    Bischoff, J.R.2    Mathews, M.B.3
  • 41
    • 0028322957 scopus 로고
    • Differential effect of p53 on the promoters of mouse DNA polymerase β gene and proliferating-cell-nuclear-antigen gene
    • Yamaguchi M, Hayashi Y, Matsuoka S, Takahashi T, Matsukage A. Differential effect of p53 on the promoters of mouse DNA polymerase β gene and proliferating-cell-nuclear-antigen gene. Eur J Biochem 1994; 221: 227-237.
    • (1994) Eur J Biochem , vol.221 , pp. 227-237
    • Yamaguchi, M.1    Hayashi, Y.2    Matsuoka, S.3    Takahashi, T.4    Matsukage, A.5
  • 42
    • 0025023637 scopus 로고
    • DNA polymerase δ and PCNA: Actions and interactions
    • Fairman MP. DNA polymerase δ and PCNA: actions and interactions. J. Cell Sci 1990; 95: 1-4.
    • (1990) J. Cell Sci , vol.95 , pp. 1-4
    • Fairman, M.P.1
  • 43
    • 0025328320 scopus 로고
    • Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin
    • Tsurimoto T, Melendy T, Stillman B. Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin Nature 1990; 346: 534-539.
    • (1990) Nature , vol.346 , pp. 534-539
    • Tsurimoto, T.1    Melendy, T.2    Stillman, B.3
  • 44
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltavai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74: 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltavai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 45
    • 0007719984 scopus 로고
    • Molecular basis of human B and T cell neoplasia
    • Klein G, ed. New York, NY (USA): Raven Press
    • Croce CM, Erikson J, Tsujimoto Y, Nowell PC. Molecular basis of human B and T cell neoplasia. In: Klein G, ed. Advances in Viral Oncology. New York, NY (USA): Raven Press, 1987: 35-51.
    • (1987) Advances in Viral Oncology , pp. 35-51
    • Croce, C.M.1    Erikson, J.2    Tsujimoto, Y.3    Nowell, P.C.4
  • 46
    • 0028214472 scopus 로고
    • The Bcl-2 protein: A prognostic indicator strongly related to p53 protein in lymph node negative breast cancer patients
    • Silvestrini R, Veneroni S, Daidone MG, et al. The Bcl-2 protein: a prognostic indicator strongly related to p53 protein in lymph node negative breast cancer patients. JNCI 1994; 86: 499-504.
    • (1994) JNCI , vol.86 , pp. 499-504
    • Silvestrini, R.1    Veneroni, S.2    Daidone, M.G.3
  • 47
    • 0030592926 scopus 로고    scopus 로고
    • Bcl-2 overexpression and smoking history in head and neck cancer
    • Ogden GR. Bcl-2 overexpression and smoking history in head and neck cancer. JNCI 1996; 88: 1864-1865.
    • (1996) JNCI , vol.88 , pp. 1864-1865
    • Ogden, G.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.