Design and synthesis of novel conformationally restricted peptide secondary structure mimetics

Organic Letters

Volumn 2, Issue 3, 2000, Pages 301-302

  Kim, Hwa Ok ^a   Nakanishi, Hiroshi ^a,b   Lee, Min S ^a,b   Kahn, Michael ^a,b  

^a Molecumetics Ltd   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000157071     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol990355r     Document Type: Article

References (11)

1. (a) Kahn, M.; Eguchi, M.; Kim, H.-O. WO98/49168.
2. (b) Peptide Secondary Structure Mimetics. Tetrahedron (Symposia-in-print; no. 50, Kahn, M., Ed.) 1993, 49, 3444.
3. (c) Kahn, M. Synlett 1993, 821.
4. (d) Kim, H.-O.; Kahn, M. Tetrahedron Lett. 1997, 38, 6483.
5. (e) Kim, H.-O.; Lum, C.; Lee, M. S. Tetrahedron Lett. 1997, 38, 4935.
6. (f). Ogbu, C. O.; Qabar, M.N.; Boatman, P. D.; Urban, J.; Meara, J. P.; Ferguson, M. D.; Tulinsky, J.; Lum, C.; Babu, S.; Blaskovich, M. A.; Nakanishi, H.; Ruan, F.; Cao, B.; Minarik, R.; Little, T.; Nelson, S.; Nguyen, M.; Gall, A.; Kahn, M. Bioorganic Med. Chem. Lett. 1998, 8, 2321.
7. (g) Eguchi, M.; Lee, M. S.; Nakanishi, H.; Kahn, M. J. Am. Chem. Soc., in press.
8. Hanessian, S.; McNaughton-Smith, G.; Lombart, H.-G.; Lubell, W. D. Tetrahedron 1997, 53, 12789.
9. Wasserman, H. H.; Ho, W.-B. J. Org. Chem. 1994, 59, 4364.
10. +).
11. R 24.1 and 24.7; 2:1 ratio.