Synthesis and absolute configuration of (1S,8S)-as-hydrindacene-1,8-diol as determined by the circular dichroism exciton chirality method

Tetrahedron Letters

Volumn 46, Issue 1, 2005, Pages 75-78

  Vandyck, Koen ^a   Matthys, Bavo ^a   Van Der Eycken, Johan ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

As hydrindacene 1,8 diol; Chiral ligands; Circular dichroism; Exciton chirality method

Indexed keywords

1,2,3,6,7,8 HEXAHYDROINDACENE 1,8 DIOL; 2 METHYLFURAN; 2,3,6,7 TETRAHYDROINDACENE 1,8 DIONE; 8 HYDROXY 3,6,7,8 TETRAHYDRO 2H INDACEN 1 ONE; ALCOHOL DERIVATIVE; BENZOIC ACID DERIVATIVE; BIS(4 DIMETHYLAMINO)BENZOATE; INDAN DERIVATIVE; LIGAND; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHIRALITY; CIRCULAR DICHROISM; ENANTIOSELECTIVITY; HYDROGENATION; SYNTHESIS;

EID: 9944263490     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.11.028     Document Type: Article

References (16)

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9. 2), 132.3 (CH), 134.6 (C), 156.3 (C), 203.5 (C) ppm
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11. 2), 75.3 (CH), 126.0 (CH), 131.7 (CH), 133.5 (C), 142.2 (C), 144.8 (C), 154.9 (C), 210.3 (C) ppm; HPLC: Chiralcel OD-H column, solvent: n-hexane/EtOH (98:2), flow rate=1 mL/min, T = 35°C, retention times = (8S)-6 =11.5 min, (8R)-6 =12.8 min
12. 2), 75.7 (CH), 124.9 (CH), 141.3 (C), 142.0 (C) ppm
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14. N. Harada, and K. Nakanishi Circular Dichroic Spectroscopy-Exciton Coupling in Organic Stereochemistry 1983 Oxford University Oxford
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16. 4 in MeOH