Pupil assessment in optic nerve disorders

Eye

Volumn 18, Issue 11, 2004, Pages 1175-1181

  Bremner, Fion D ^a  

^a NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Afferent defect; Optic nerve; Perimetry; Pupil; Reflex

Indexed keywords

ACCURACY; ARTICLE; DIAGNOSTIC VALUE; DISEASE SEVERITY; ELECTRODIAGNOSIS; HUMAN; LIGHT; MEDICAL ASSESSMENT; OPTIC NERVE DISEASE; OPTIC NERVE FIBER; PERIMETRY; PHOTOSTIMULATION; PROGNOSIS; PUPIL; PUPIL REFLEX; PUPILLOGRAPHY; SENSITIVITY AND SPECIFICITY; TIME; VISUAL FIELD; VISUAL IMPAIRMENT; VISUAL STIMULATION;

EID: 9944253226     PISSN: 0950222X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.eye.6701560     Document Type: Article

References (85)

1. Thompson HS, Corbett JJ. Asymmetry of pupillomotor input. Eye 1991; 5: 36-39.
2. Hirschberg J. Neuritis retrobulbaris. Zentralbl Prakt Augenheilkd 1884; 8: 185-186.
3. Gunn RM. Functional or hysterical amblyopia. Ophthalmol Rev 1902; 21: 271-280.
4. Kestenbaum A. Clinical Methods of Neuro-ophthalmological Investigation, 1st ed. Grune & Stratton: New York, 1946 pp 281-291.
5. Cox TA. Pupillary escape. Neurology 1992; 42: 1271-1273.
6. Enyedi LB, Dev S, Cox TA. A comparison of the Marcus Gunn and alternating light tests for afferent pupillary defects. Ophthalmology 1998; 105: 871-873.
7. Levatin P. Pupillary escape in disease of the retina or optic nerve. Arch Ophthalmol 1959; 62: 768-779.
8. Thompson HS. Afferent pupillary defects: pupillary findings associated with defects of the afferent limb of the pupil light reflex arc. Am J Ophthalmol 1966; 62: 860-873.
9. Thompson HS. Pupillary signs in the diagnosis of optic nerve disease. Trans Ophthalmol Soc UK 1976; 96: 377-381.
10. Digre KB. Principles and techniques of examination of the pupils, accommodation, and the lacrimal system. In: Miller, Newman (eds). Walsh & Hoyt's Clinical Neuroophthalmology, 5th ed. 1998 p 941.
11. Thompson HS, Corbett JJ, Cox TA. How to measure the relative afferent pupillary defect. Surv Ophthalmol 1981; 26: 39-42.
12. Arnold RW. Quantification of the afferent papillary defect by double polarized filter. Arch Ophthalmol 1990; 108: 1666-1667.
13. Rosenberg ML, Oliva A. The use of crossed polarized filters in the measurement of the relative afferent pupillary defect. Am J Ophthalmol 1990; 110: 62-65.
14. Ramsay A, Williamson TH, Parks S, Keating D. Crossed polarising filters to measure relative afferent pupillary defects: reproducibility, correlation with neutral density filters and use in central retinal vein occlusion. Eye 1995; 9: 624-628.
15. McCormick A, Bhola R, Brown L, Squirrel D, Giles J, Pepper I. Quantifying relative afferent papillary defects using a Sbisa bar. Br J Ophthalmol 2002; 86: 985-987.
16. Thompson HS, Jiang MQ. Letter to the editor. Ophthalmology 1987; 94: 1360-1362.
17. Kawasaki A, Moore P, Kardon RH. Long-term fluctuation of relative afferent pupillary defect in subjects with normal visual function. Am J Ophthalmol 1996; 122: 875-882.
18. Lam BL, Thompson HS. An anisocoria produces a small relative afferent pupillary defect in the eye with the smaller pupil. J Neuro-ophthalmol 1999; 19: 153-159.
19. Lam BL, Thompson HS. A unilateral cataract produces a relative afferent pupillary defect in the contralateral eye. Ophthalmology 1990; 97: 334-338.
20. Stern HJ. A simple method for the early diagnosis of abnormality of the pupillary reaction. Br J Ophthalmol 1944; 28 275-276.
21. Miller SD, Thompson HS. Edge-light pupil cycle time. Br J Ophthalmol 1978; 62: 495-500.
22. Miller SD, Thompson HS. Pupil cycle time in optic neuritis. Am J Ophthalmol 1978; 85: 635-642.
23. Hamilton W, Drewry RD. Edge-light pupil cycle time and optic nerve disease. Ann Ophthalmol 1983; 15: 714-721.
24. Kirkham TH, Coupland SG. Multiple regression analysis of diagnostic predictors in optic nerve disease. Can J Neurol Sci 1981; 8: 67-72.
25. Manor RS, Yassur Y, Ben-Sira I. Pupil cycle time in non-compressive optic neuropathy. Ann Ophthalmol 1982; 14: 546-550.
26. Weinstein JM, Van Gilder JC, Thompson HS. Pupil cycle time in optic nerve compression. Am J Ophthalmol 1980; 89: 263-267.
27. Manor RS, Yassur Y, Ben-Sira I. Pupil cycle time in space-occupying lesions of anterior optic pathways. Ann Ophthalmol 1982; 14: 1030-1031.
28. Howarth PA, Heron G, Whittaker L. The measurement of pupil cycling time. Graefe's Arch Clin Exp Ophthalmol 2000; 238: 826-832.
29. Terdiman J, Smith JD, Stark L. Pupil response to light and electrical stimulation: static and dynamic characteristics. Brain Res 1969; 16: 288-292.
30. Smith JD, Masek GA, Ichinose LY, Watanabe T, Stark L. Single neuron activity in the pupillary system. Brain Res 1970; 24: 219-234.
31. Barlow RB, Snodderly DM, Swadlow HA. Intensity coding in primate visual system. Exp Brain Res 1978; 31: 163-177.
32. Cox TA, Thompson HS, Hayreh SS, Snyder JE. Visual evoked potential and pupillary signs: a comparison in optic nerve disease. Arch Ophthalmol 1982; 100: 1603-1607.
33. Lowenstein O, Loewenfeld fE. Electronic pupillography: a new instrument and some clinical applications. Arch Ophthalmol 1958; 59: 352-363.
34. Fison PN, Garlick DJ, Smith SE. Assessment of unilateral afferent pupillary defects by pupillography. Br J Ophthalmol 1979; 63: 195-199.
35. Harms H. Grundlagen, Methodik und Bedeutung der Pupillenperimetrie fur die Physiologie und Pathologie des Sehorgans. Graefe's Arch Clin Exp Ophthalmol 1949; 149: 1-44.
36. Burke DW, Ogle KN. Comparison of visual and pupillary light thresholds in periphery. Arch Ophthalmol 1964; 71: 400-408.
37. Bresky R, Charles S. Pupillomotor perimetry. Am J Ophthalmol 1969; 66: 108-112.
38. Narasaki S, Kawai K, Kubota S, Noguchi J. Videopupillographic perimetry and its clinical application. Jpn J Ophthalmol 1974; 18: 253-274.
39. Aoyama T. Pupillographic perimetry. Acta Soc Ophthalmol Japan 1975; 79: 1247-1256.
40. Cibis GW, Campos EC, Aulhorn E. Pupillary hemiakinesia in suprageniculate lesions. Arch Ophthalmol 1975; 93: 1322-1327.
41. Hellner KA, Jensen W, Muller-Jensen A. Video-processing pupillography as a method for objective perimetry in pupillary hemiakinesia. Doc Ophthalmol 1977; 14: 221-226.
42. Fankhauser F, Flammer J. Puptrak 1.0: a new semiautomated system for pupillometry with the Octopus perimeter. Doc Ophthalmol 1990; 73: 235-248.
43. Alexandridis E, Krastel H. New equipment for pupillographic perimetry. Neuro-ophthalmology 1990; 10: 331-336.
44. Kardon RH, Aydin-Kirkali P, Thompson HS. Automated pupil perimetry: pupil field mapping in patients and normal subjects. Ophthalmology 1991; 98: 485-496.
45. Yoshitomi T, Matsui T, Tanakadate A, Ishikawa S. Comparison of threshold visual perimetry and objective pupil perimetry in clinical patients. J Neuro-ophthalmol 1999; 19: 89-99.
46. Wilhelm H, Neitzel J, Wilhelm B, Beuel S, Ludtke H, Kretschmann U et al. Pupil perimetry using M-sequence stimulation technique. Invest Ophthalmol Vis Sci 2000; 41: 1229-1238.
47. Bergamin O, Turtschi S, Schotzau A, Hendrickson Ph, Flammer J, Zulauf M et al. Pupil perimetry with the Octopus 1-2-3: first experience. In: RP Mills, & M Wall (eds). Proceedings of the XIth International Perimetric Society Meeting. Kugler Publications: Amsterdam/New York, 1995.
48. Schweitzer NMJ. Threshold measurements on the light reflex of the pupil in the dark adapted eye. Doc Ophthalmol 1956; 10: 1-78.
49. Ellis CJK. The pupillary light reflex in normal subjects. Br J Ophthalmol 1981; 65: 754-759.
50. Kawasaki A, Moore P, Kardon RH. Variability of the relative afferent pupillary defect. Am J Ophthalmol 1995; 120: 622-633.
51. Schmid R, Wilhelm B, Wilhelm H. Pupillomotor campimetry in normals. Neuro-ophthalmology 1999; 23: 7-13.
52. Hong S, Narkiewicz J, Kardon RH. Comparison of pupil perimetry and visual perimetry in normal eyes: decibel sensitivity and variability. Invest Ophthalmol Vis Sci 2001; 42: 957-965.
53. Bullock JD. Relative afferent pupillary defect in the 'better' eye. J Neuro-ophthalmol 1990; 10: 45-51.
54. Thompson HS, Montague P, Cox TA, Corbett JJ. The relationship between visual acuity, pupillary defect and visual field loss. Am J Ophthalmol 1982; 93: 681-688.
55. Brown RH, Zilis JD, Lynch MG, Sanborn GE. The afferent pupillary defect in asymmetric glaucoma. Arch Ophthalmol 1987; 105: 1540.
56. Johnson LN, Hill RA, Bartholomew MJ. Correlation of afferent pupillary defect with visual field loss on automated perimetry. Ophthalmology 1988; 95: 1649-1655.
57. Kardon RH, Haupert CL, Thompson HS. The relationship between static perimetry and the relative afferent pupillary defect. Am J Ophthalmol 1993; 115: 351-356.
58. Lagreze W-DA, Kardon RH. Correlation of relative afferent papillary defect and estimated retinal ganglion cell loss. Graefe's Arch Clin Exp Ophthalmol 1998; 236: 401-404.
59. Stone J, Fukuda Y. Properties of cat retinal ganglion cells: a comparison of W-cells with X- and Y-cells. J Neurophysiol 1974; 37: 722-748.
60. Leventhal AG, Rodieck RW, Dreher B. Retinal ganglion cell classes in the old world monkey: morphology and central projections. Science 1981; 213: 1139-1142.
61. Nakanishi M, Mashima Y, Hiida Y, Suzuki S, Oguchi Y. Two cases of Leber's hereditary optic neuropathy diagnosed as psychogenic visual loss. Ganka (Ophthalmology) 1994; 36: 811-814.
62. Nikoskelainen EK, Huopenen K, Juvonen V, Lamminen T, Nummelin K, Savontaus ML. Ophthalmologic findings in Leber's hereditary optic neuropathy with special reference to mtDNA mutations. Ophthalmology 1996; 103: 504-514.
63. Bynke H, Bynke G, Rosenberg T. Is Leber's hereditary optic neuropathy a retinal disorder? Report of a case. Neuroophthalmology 1996; 16: 115-123.
64. Wakakura M, Yokoe J. Evidence for preserved direct pupil light response in Leber's hereditary optic neuropathy. Br J Ophthalmol 1995; 79: 442-446.
65. Jakobson DM, Stone EM, Miller NR, Pollock SC, Fletcher WA, McNussen PJ. Relative afferent pupil defects in patients with Leber's hereditary optic neuropathy and unilateral visual loss. Am J Ophthalmol 1998; 126: 291-295.
66. Ludtke H, Kriegbaum C, Leo-Kottler B, Wilhelm H. Pupillary light reflexes in patients with Leber's hereditary optic neuropathy. Graefe's Arch Clin Exp Ophthalmol 1999; 237: 207-211.
67. Bremner FD, Shallo-Hoffmann J, Riordan-Eva P, Smith SE. Comparing pupil function with visual function in patients with Leber's hereditary optic neuropathy. Invest Ophthalmol Vis Sci 1999; 40 2528-2534.
68. Bremner FD, Tomlin EA, Shallo-Hoffmann J, Votruba M, Smith SE. The pupil in dominant optic atrophy. Invest Ophthalmol Vis Sci 2001; 42: 675-678.
69. Bremner FD, Tomlin EA, Shallo-Hoffmann J, Smith SE. Poor recovery of the pupil light reflex following acute optic neuritis. Neuro-ophthalmology 2001; 25: 56.
70. Bremner FD, Tomlin EA, Shallo-Hoffmann J, Smith SE. The pupil in optic nerve disease. In: Sharpe JA (ed). 'Neuro-ophthalmology at the beginning of the new millenium'. Medimond Medical Publications: Englewood, NJ, USA, 2000, pp 23-27.
71. Halliday AM, McDonald WI, Mushin J. Delayed visual evoked responses in optic neuritis. Lancet 1972; 1: 982-985.
72. Cox TA, Thompson HS, Hayreh SS, Snyder JE. Visual evoked potential and pupillary signs: a comparison in optic nerve disease. Arch Ophthalmol 1982; 100: 1603-1607.
73. Ellis CJK. The afferent pupillary defect in acute optic neuritis. J Neurol Neurosurg Psychiatry 1979; 42: 1008-1017.
74. Bovino JA, Burton TC. Measurement of the relative afferent pupillary defect in retinal detachment. Am J Ophthalmol 1980; 90 19-21.
75. Folk JC, Thompson HS, Farmer SG, O'Gorman TW, Dreyer RF. Relative afferent pupillary defect in eyes with retinal detachment. Ophthalmic Surg 1987; 18: 757-759.
76. Curcio CA, Allen KA. Topography of ganglion cells in human retina. J Comp Neurol 1990; 300: 5-25.
77. Quigley HA, Miller NR, Green WR. The pattern of optic nerve fiber loss in anterior ischaemic optic neuropathy. Am J Ophthalmol 1985; 100: 769-776.
78. Levin PS, Newman SA, Quigley HA, Miller NR. A clinicopathologic study of optic neuropathies associated with intracranial mass lesions with quantification of remaining axons. Am J Ophthalmol 1983; 95: 295-306.
79. Kerrison JB, Buchanan K, Rosenberg ML, Clark R, Andreason K, Altaro DV et al. Quantification of optic nerve axon loss associated with a relative afferent pupillary defect in the monkey. Arch Ophthalmol 2001; 119: 1333-1341.
80. Rajan MS, Bremner FD, Riordan-Eva P. Pupil perimetry in the diagnosis of functional visual field loss. J Roy Soc Med 2002; 95: 498-500.
81. Thompson H, Watzke R, Weinstein J. Pupillary dysfunction in macular disease. Trans Am Ophthalmol Soc 1980; 78: 311-317.
82. Newsome DA, Milton RC, Gass JDM. Afferent pupillary defect in macular degeneration. Am J Ophthalmol 1981; 92: 396-402.
83. Folk JC, Thompson HS, Han D, Brown CK. Visual function abnormalities in central serous retinopathy. Arch Ophthalmol 1984; 102: 1299-1302.
84. Kawasaki A, Kardon RH. Disorders of the pupil. Neuro-ophthalmology 2001; 14: 149-168.
85. Alford MA, Nerad JA, Carter KD. Predictive value of the initial quantified relative afferent pupillary defect in 19 consecutive patients with traumatic optic neuropathy. Ophthal Plast Reconstr Surg 2001; 17: 323-327.