The screening of extracts from Goniothalamus scortechinii, Aralidium pinnatifidum and Andrographis paniculata for anti-malarial activity using the lactate dehydrogenase assay

Journal of Ethnopharmacology

Volumn 82, Issue 2-3, 2002, Pages 239-242

  Siti Najila, M J ^a   Noor Rain, A ^a   Mohamad Kamel, A G ^b   Syed Zahir, S I ^b   Khozirah, S ^c   Lokman Hakim, S ^a   Zakiah, I ^a   Azizol, A K ^c  

^a INSTITUTE FOR MEDICAL RESEARCH   (Malaysia)

^b UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^c Forest Researh Institute Malaysia   (Malaysia)

Author keywords

In vitro anti malarial activity; Lactate dehydrogenase assay; Medicinal plants; Plasmodium falciparum

Indexed keywords

ANDROGRAPHIS PANICULATA EXTRACT; ARALIDIUM PINNATIFIDUM EXTRACT; CHLOROFORM; CHLOROQUINE; GONIOTHALAMUS SCORTECHINII EXTRACT; LACTATE DEHYDROGENASE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; ENZYME ASSAY; IC 50; IN VITRO STUDY; NONHUMAN; PLASMODIUM FALCIPARUM;

ALDEHYDE OXIDOREDUCTASES; ANDROGRAPHIS; ANIMALS; ANNONACEAE; ANTIMALARIALS; BIOLOGICAL ASSAY; DRUG EVALUATION, PRECLINICAL; HUMANS; PLANT EXTRACTS; PLANT LEAVES; PLANT STEMS; PLASMODIUM FALCIPARUM;

EID: 0036803304     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(02)00183-6     Document Type: Article

References (8)

1. Montgomery R., Eyles D.E. Chloroquine resistant falciaprum malaria in Malaya. Transactions of the Royal Society of Tropical Medicine and Hygiene. 57:1963;409-416.
2. Burkill I.H. A Dictionary of the Economic Products of the Malay Peninsula. 1 and 2:1935;Ministry of Agriculture, Malaysia.
3. Hakim S.L., Sharifah Roohi S.W.A., Zurkunai Y., Noor Rain A., Mansor S.M., Palmer K., Navaratnam V., Mak J.W. Plasmodium falciparum:increased proportion of severe resistance (RII and RIII) to chloroquine and high rate of resistance to sulfadoxine-pyrimethamine in Peninsular Malaysia after two decades. Transactions of the Royal Society of Tropical Medicine and Hygiene. 90:1996;924-927.
4. Makler M.T., Hinrichs D.J. Measurement of the lactate dehydrogenase activity of Plasmodium falciparum as an assessment of parasitaemia. American Journal of Tropical Medicine and Hygiene. 48:(2):1993;205-210.
5. Makler M.T., Ries J.M., Williams J.A., Bancroft J.E., Piper R.C., Gibbins B.L., Hinrichs D.J. Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity. American Journal of Tropical Medicine and Hygiene. 48:(6):1993;739-741.
6. Slamet Trijono, Lim P.K.C., Mak J.W., Storey J., Noor Rain Abdullah. Sensitivity of Malaysian isolates of Plasmodium falciparum to a number of antimalarials using the WHO in vitro micro test. Tropical Biomedicine. 8:1991;85-87.
7. Trager W., Jensen J.B. Human malaria parasites in continuous culture. Science. 193:(4254):1976;673-675.
8. Trager W., Jensen J.B. Plasmodium falciparum in culture: use of outdated erythrocytes and description of the candle jar method. Journal of Parasitology. 63:(5):1977;883-886.