메뉴 건너뛰기




Volumn 2, Issue 3, 1996, Pages 471-475

Initial clinical trial of the retinoid receptor pan agonist 9-cis retinoic acid

Author keywords

[No Author keywords available]

Indexed keywords

ALITRETINOIN; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR AGONIST; UNCLASSIFIED DRUG;

EID: 9044235574     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (67)

References (34)
  • 1
    • 0021249914 scopus 로고
    • Retinoic acid: Biochemistry, pharmacology, toxicology, and therapeutic use
    • Chytil, F. Retinoic acid: Biochemistry, pharmacology, toxicology, and therapeutic use. Pharmacol. Rev., 36: 93S-100S, 1984.
    • (1984) Pharmacol. Rev. , vol.36
    • Chytil, F.1
  • 6
    • 0028197110 scopus 로고
    • Vitamin A receptors
    • Mangelsdorf, D. J. Vitamin A receptors. Nutr. Rev., 52: S32-S44, 1994.
    • (1994) Nutr. Rev. , vol.52
    • Mangelsdorf, D.J.1
  • 7
    • 0025089467 scopus 로고
    • Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17
    • Washington DC
    • Borrow, J., Goddard, A. D., Sheer, D., and Solomon, E. Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17. Science (Washington DC), 249: 1577-1580, 1990.
    • (1990) Science , vol.249 , pp. 1577-1580
    • Borrow, J.1    Goddard, A.D.2    Sheer, D.3    Solomon, E.4
  • 8
    • 0025043959 scopus 로고
    • The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor a gene to a novel transcribed locus
    • de The, J., Chomienne, C., Lannote, M., Degos, L., and Dejean, A. The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor a gene to a novel transcribed locus. Nature (Lond.), 347: 558-561, 1990.
    • (1990) Nature (Lond.) , vol.347 , pp. 558-561
    • De The, J.1    Chomienne, C.2    Lannote, M.3    Degos, L.4    Dejean, A.5
  • 9
    • 0025270737 scopus 로고
    • Nuclear receptor that identifies a novel retinoic acid response pathway
    • Mangelsdorf, D. J., Ong, E. S., Dyck, J. A., and Evans, R. M. Nuclear receptor that identifies a novel retinoic acid response pathway. Nature (Lond.), 345: 224-229, 1990.
    • (1990) Nature (Lond.) , vol.345 , pp. 224-229
    • Mangelsdorf, D.J.1    Ong, E.S.2    Dyck, J.A.3    Evans, R.M.4
  • 13
    • 0028567532 scopus 로고
    • Cancer combination chemotherapy with retinoids: Experimental rationale
    • Baltimore
    • Bollag, W , Majewski, S , and Jablonska, S. Cancer combination chemotherapy with retinoids: experimental rationale. Leukemia (Baltimore), 8: 1453, 1994.
    • (1994) Leukemia , vol.8 , pp. 1453
    • Bollag, W.1    Majewski, S.2    Jablonska, S.3
  • 14
    • 0023766114 scopus 로고
    • Automated determination of 13-cis- and all-trans-retinoic acid, their 4-oxo metabolites and retinol in plasma, amniotic fluid and embryo by reversed-phase high-performance liquid chromatography with a precolumn switching technique
    • Creech-Kraft, J., Echoff, C , Kuhnz, W., Lofberg, B., and Nau, H. Automated determination of 13-cis- and all-trans-retinoic acid, their 4-oxo metabolites and retinol in plasma, amniotic fluid and embryo by reversed-phase high-performance liquid chromatography with a precolumn switching technique. J. Liq. Chromat., 11: 2051-2069, 1988.
    • (1988) J. Liq. Chromat. , vol.11 , pp. 2051-2069
    • Creech-Kraft, J.1    Echoff, C.2    Kuhnz, W.3    Lofberg, B.4    Nau, H.5
  • 17
    • 0027524546 scopus 로고
    • Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans retinoic acid, and its modulation by ketoconazole
    • Rigas, J. R., Francis, P. A, Muindi, J. R. F., Huselton, C., DeGrazia, F., Kris, M. G., Young, C. W., and Warrell, R, P., Jr. Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans retinoic acid, and its modulation by ketoconazole. J. Natl. Cancer Inst., 85: 1921-1926, 1993.
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 1921-1926
    • Rigas, J.R.1    Francis, P.A.2    Muindi, J.R.F.3    Huselton, C.4    DeGrazia, F.5    Kris, M.G.6    Young, C.W.7    Warrell Jr., R.P.8
  • 21
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
    • Keller, H., Dreyer, C., Medin, J., Mahfoudi, A., Ozato, K., and Wahli, W Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc. Natl. Acad. Sci. USA, 90: 2160-2164, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2160-2164
    • Keller, H.1    Dreyer, C.2    Medin, J.3    Mahfoudi, A.4    Ozato, K.5    Wahli, W.6
  • 22
    • 0024557718 scopus 로고
    • Lipid metabolism and retinoid therapy
    • Marsden, J. R. Lipid metabolism and retinoid therapy. Pharmacol. Ther., 40: 55-65, 1989.
    • (1989) Pharmacol. Ther. , vol.40 , pp. 55-65
    • Marsden, J.R.1
  • 23
    • 0026342117 scopus 로고
    • RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements
    • Yu, V. C., Delsert, C., Andersen, B., Holloway, J. M., Devary, O. V., Naar, A. M., Kim, S. Y., Boutin, J. M., Glass, C. K., and Rosenfeld, M. G. RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell, 67: 1251-1266, 1991.
    • (1991) Cell , vol.67 , pp. 1251-1266
    • Yu, V.C.1    Delsert, C.2    Andersen, B.3    Holloway, J.M.4    Devary, O.V.5    Naar, A.M.6    Kim, S.Y.7    Boutin, J.M.8    Glass, C.K.9    Rosenfeld, M.G.10
  • 25
    • 0026736067 scopus 로고
    • Heterodimerization of thyroid hormone (TH) receptor with H-2RIIBP (RXRβ) enhances DNA binding and TH-dependent transcriptional activation
    • Hallenbeck, P. L., Marks, M. S., Lippoldt, R. E., Ozato, K., and Nikodem, V. M. Heterodimerization of thyroid hormone (TH) receptor with H-2RIIBP (RXRβ) enhances DNA binding and TH-dependent transcriptional activation. Proc. Natl. Acad. Sci. USA. 89: 5572-5576, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5572-5576
    • Hallenbeck, P.L.1    Marks, M.S.2    Lippoldt, R.E.3    Ozato, K.4    Nikodem, V.M.5
  • 26
    • 0026536522 scopus 로고
    • Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors
    • Zhang, X. K., Hoffman, B., Tran, P. B. V., Graupner, G., and Pfahl, M. Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature (Lond.), 355: 441-446, 1992.
    • (1992) Nature (Lond.) , vol.355 , pp. 441-446
    • Zhang, X.K.1    Hoffman, B.2    Tran, P.B.V.3    Graupner, G.4    Pfahl, M.5
  • 27
    • 0028194869 scopus 로고
    • Recombinant thyroid hormone receptor and retinoid X receptor stimulate ligand-dependent transcription in vitro
    • Lee, I. J., Driggers, P. H., Medin, J. A., Nikodem, V. M., and Ozato, K. Recombinant thyroid hormone receptor and retinoid X receptor stimulate ligand-dependent transcription in vitro. Proc. Natl. Acad. Sci. USA, 91: 1647-1651, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1647-1651
    • Lee, I.J.1    Driggers, P.H.2    Medin, J.A.3    Nikodem, V.M.4    Ozato, K.5
  • 28
    • 0028782187 scopus 로고
    • The molecular basis of thyroid hormone action
    • Brent, G. A. The molecular basis of thyroid hormone action. N. Engl. J. Med, 331: 847-853, 1994.
    • (1994) N. Engl. J. Med , vol.331 , pp. 847-853
    • Brent, G.A.1
  • 29
    • 0026536835 scopus 로고
    • Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: Implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia
    • Muindi, J., Frankel, S., Miller, W., Jakubowski, A., Scheinberg, D. A., Young, C. W , Dmitrovsky, E., and Warrell, R. P., Jr. Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia. Blood, 79: 299-303, 1992.
    • (1992) Blood , vol.79 , pp. 299-303
    • Muindi, J.1    Frankel, S.2    Miller, W.3    Jakubowski, A.4    Scheinberg, D.A.5    Young, C.W.6    Dmitrovsky, E.7    Warrell Jr., R.P.8
  • 30
    • 0028897374 scopus 로고
    • Pharmacokinetics of 9-cis-retinoic acid in the rhesus monkey
    • Adamson, P. C., Murphy, R. F., Godwin, K. A., Ulm, E. H., and Balis, F. M. Pharmacokinetics of 9-cis-retinoic acid in the rhesus monkey. Cancer Res., 55: 482-485, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 482-485
    • Adamson, P.C.1    Murphy, R.F.2    Godwin, K.A.3    Ulm, E.H.4    Balis, F.M.5
  • 31
    • 0028243129 scopus 로고
    • Differences in the pharmacokinetic properties of orally administered all-trans-retinoic acid and 9-cis-retinoic acid in the plasma of nude mice
    • Achkar, C. C., Bentel, J M., Boylan, J. F., Scher, H. I., Gudas, L. J., and Miller, W. J. Differences in the pharmacokinetic properties of orally administered all-trans-retinoic acid and 9-cis-retinoic acid in the plasma of nude mice. Drug Metab. Dispos., 22: 451-458, 1994.
    • (1994) Drug Metab. Dispos. , vol.22 , pp. 451-458
    • Achkar, C.C.1    Bentel, J.M.2    Boylan, J.F.3    Scher, H.I.4    Gudas, L.J.5    Miller, W.J.6
  • 32
    • 0028212177 scopus 로고
    • Glucuronidation and isomerization of all-trans- and 13- cis-retinoic acid by liver microsomes of phenobarbital or 3-methylcholanthrene-treated rats
    • Sass, J. O., Forster, A , Bock, K. W., and Nau, H. Glucuronidation and isomerization of all-trans- and 13- cis-retinoic acid by liver microsomes of phenobarbital or 3-methylcholanthrene-treated rats. Biochem. Pharmacol., 47: 485-492, 1994.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 485-492
    • Sass, J.O.1    Forster, A.2    Bock, K.W.3    Nau, H.4
  • 34
    • 0028894263 scopus 로고
    • Enhanced efficacy of combinations of retinoic acid- and retinoid X receptor-selective retinoids and α-interferon in inhibition of cervical carcinoma cell proliferation
    • Lotan, R., Dawson, M. I., Zou, C. C., Jong, L., Lotan, D., and Zou, C. P. Enhanced efficacy of combinations of retinoic acid- and retinoid X receptor-selective retinoids and α-interferon in inhibition of cervical carcinoma cell proliferation. Cancer Res., 55: 232-236, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 232-236
    • Lotan, R.1    Dawson, M.I.2    Zou, C.C.3    Jong, L.4    Lotan, D.5    Zou, C.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.