메뉴 건너뛰기




Volumn 11, Issue 5, 1997, Pages 981-986

Lack of dose-response with pancrease MT for the treatment of exocrine pancreatic insufficiency in adults

Author keywords

[No Author keywords available]

Indexed keywords

FECES LIPID; MICROSPHERE; PANCREAS ENZYME; PANCRELIPASE; PLACEBO; TRIACYLGLYCEROL LIPASE;

EID: 9844222492     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.1997.00245.x     Document Type: Article
Times cited : (12)

References (45)
  • 1
    • 0018758927 scopus 로고
    • Medical treatment of pancreatic insufficiency
    • DiMagno EP. Medical treatment of pancreatic insufficiency. Mayo Clin Proc 1979; 54: 435-42.
    • (1979) Mayo Clin Proc , vol.54 , pp. 435-442
    • Dimagno, E.P.1
  • 2
    • 0023001995 scopus 로고
    • Fate of pancreatic enzymes during small intestinal aboral transit in humans
    • Layer P, Go VL, DiMagno EP. Fate of pancreatic enzymes during small intestinal aboral transit in humans. Am J Physiol 1986; 251: G475-80.
    • (1986) Am J Physiol , vol.251
    • Layer, P.1    Go, V.L.2    Dimagno, E.P.3
  • 3
    • 0022574609 scopus 로고
    • Treatment of steatorrhea in chronic pancreatitis
    • Graham DY. Treatment of steatorrhea in chronic pancreatitis. HospPract 1986:21: 125-9.
    • (1986) HospPract , vol.21 , pp. 125-129
    • Graham, D.Y.1
  • 4
    • 0027979296 scopus 로고
    • Enzyme therapy for pancreatic insufficiency: Present status and future needs
    • Lebenthal E, Rolston DD, Holsclaw DS. Enzyme therapy for pancreatic insufficiency: present status and future needs. Pancreas 1994; 9: 1-12.
    • (1994) Pancreas , vol.9 , pp. 1-12
    • Lebenthal, E.1    Rolston, D.D.2    Holsclaw, D.S.3
  • 6
    • 0029088291 scopus 로고
    • Maldigestion associated with exocrine pancreatic insufficiency: Implications of gastrointestinal physiology and properties of enzyme preparations for a cause-related and patient-tailored treatment
    • Bruno MJ, Haverkort EB, Tytgat GN, van Leeuwen DJ. Maldigestion associated with exocrine pancreatic insufficiency: implications of gastrointestinal physiology and properties of enzyme preparations for a cause-related and patient-tailored treatment. Am J Gastroenterol 1995; 90: 1383-93.
    • (1995) Am J Gastroenterol , vol.90 , pp. 1383-1393
    • Bruno, M.J.1    Haverkort, E.B.2    Tytgat, G.N.3    Van Leeuwen, D.J.4
  • 7
    • 0028332006 scopus 로고
    • Clinical pharmacology of pancreatic enzymes in patients with cystic fibrosis and in vitro performance of microencapsulated formulations
    • Kraisinger M, Hochhaus G, Stecenko A, Bowser E, Hendeles L. Clinical pharmacology of pancreatic enzymes in patients with cystic fibrosis and in vitro performance of microencapsulated formulations. J Clin Pharmacol 1994; 34: 158-66.
    • (1994) J Clin Pharmacol , vol.34 , pp. 158-166
    • Kraisinger, M.1    Hochhaus, G.2    Stecenko, A.3    Bowser, E.4    Hendeles, L.5
  • 8
    • 0021676468 scopus 로고
    • Ins and outs of pancreatic enzymes and adjuvant therapies
    • Graham DY. Ins and outs of pancreatic enzymes and adjuvant therapies. J Pediatr Gastroenterol Nutr 1984; 3(Suppl. 1): 120-6.
    • (1984) J Pediatr Gastroenterol Nutr , vol.3 , Issue.1 SUPPL. , pp. 120-126
    • Graham, D.Y.1
  • 9
    • 0025609875 scopus 로고
    • Ranitidine compared with the dimethylprostaglandin E2 analogue enprostil as adjunct to pancreatic enzyme replacement in adult cystic fibrosis
    • Heijerman HG, Lamers CB, Dijkman JH, Bakker W. Ranitidine compared with the dimethylprostaglandin E2 analogue enprostil as adjunct to pancreatic enzyme replacement in adult cystic fibrosis. Scand J Gastroenterol 1990; 178(Suppl.): 2631.
    • (1990) Scand J Gastroenterol , vol.178 , Issue.SUPPL. , pp. 2631
    • Heijerman, H.G.1    Lamers, C.B.2    Dijkman, J.H.3    Bakker, W.4
  • 10
    • 0017734203 scopus 로고
    • Enzyme replacement therapy of exocrine pancreatic insufficiency in man. Relations between in vitro enzyme activities and in vivo potency in commercial pancreatic extracts
    • Graham DY. Enzyme replacement therapy of exocrine pancreatic insufficiency in man. Relations between in vitro enzyme activities and in vivo potency in commercial pancreatic extracts. N Engl J Med 1977; 296: 1314-7.
    • (1977) N Engl J Med , vol.296 , pp. 1314-1317
    • Graham, D.Y.1
  • 11
  • 13
    • 0030022571 scopus 로고    scopus 로고
    • High- Versus low-lipase acid-resistant enzyme preparations in cystic fibrosis: A crossover randomized clinical trial
    • Lancellotti L, Cabrini G, Zanolla L, Mastella G. High- versus low-lipase acid-resistant enzyme preparations in cystic fibrosis: a crossover randomized clinical trial. J Pediatr Gastroenterol Nutr 1996; 22: 73-8.
    • (1996) J Pediatr Gastroenterol Nutr , vol.22 , pp. 73-78
    • Lancellotti, L.1    Cabrini, G.2    Zanolla, L.3    Mastella, G.4
  • 14
    • 0025886099 scopus 로고
    • Effect of pellet size of a pancreas enzyme preparation on duodenal lipolytic activity
    • Kuhnelt P, Mundlos S, Adler G. Effect of pellet size of a pancreas enzyme preparation on duodenal lipolytic activity. Z Gastroenterol 1991:29:417-21.
    • (1991) Z Gastroenterol , vol.29 , pp. 417-421
    • Kuhnelt, P.1    Mundlos, S.2    Adler, G.3
  • 15
    • 0027183314 scopus 로고
    • New methods for assessment of enzyme activity: Do they help to optimize enzyme treatment?
    • Adler G, Mundlos S. Kuhnelt P, Dreyer E. New methods for assessment of enzyme activity: do they help to optimize enzyme treatment? Digestion 1993; 54(Suppl. 2): 3-9.
    • (1993) Digestion , vol.54 , Issue.2 SUPPL. , pp. 3-9
    • Adler, G.1    Mundlos, S.2    Kuhnelt, P.3    Dreyer, E.4
  • 16
    • 0020694246 scopus 로고
    • Comparative evaluation of the therapeutic efficacy of a pH-sensitive enteric coated pancreatic enzyme preparation with conventional pancreatic enzyme therapy in the treatment of exocrine pancreatic insufficiency
    • Dutta SK, Rubin J, Harvey J. Comparative evaluation of the therapeutic efficacy of a pH-sensitive enteric coated pancreatic enzyme preparation with conventional pancreatic enzyme therapy in the treatment of exocrine pancreatic insufficiency. Gastroenterol 1983; 84: 476-82.
    • (1983) Gastroenterol , vol.84 , pp. 476-482
    • Dutta, S.K.1    Rubin, J.2    Harvey, J.3
  • 17
    • 0018722283 scopus 로고
    • An enteric-coated pancreatic enzyme preparation that works
    • Graham DY. An enteric-coated pancreatic enzyme preparation that works. Dig Dis Sei 1979; 24: 906-9.
    • (1979) Dig Dis Sei , vol.24 , pp. 906-909
    • Graham, D.Y.1
  • 18
    • 0020069865 scopus 로고
    • Pancreatic enzyme replacement: The effect of antacids or cimetidine
    • Graham DY. Pancreatic enzyme replacement: the effect of antacids or cimetidine. Dig Dis Sei 1982; 27: 485-90.
    • (1982) Dig Dis Sei , vol.27 , pp. 485-490
    • Graham, D.Y.1
  • 19
    • 0019971120 scopus 로고
    • Mechanism of increase in steatorrhea with calcium and magnesium in exocrine pancreatic insufficiency: An animal model
    • Graham DY, Sackman JVV. Mechanism of increase in steatorrhea with calcium and magnesium in exocrine pancreatic insufficiency: an animal model. Gastroenterol 1982; 83:638-44.
    • (1982) Gastroenterol , vol.83 , pp. 638-644
    • Graham, D.Y.1    Sackman, J.V.V.2
  • 20
    • 0027297656 scopus 로고
    • Fat absorption and gastroenteric pH profile in postsurgical pancreatic insufficiency: Role of the association of H2-rcceptor antagonists with pancreatic enzymes
    • Braga M, Zerbi A, Malesci A, Dal Cin S, Valentin! A, Tacconi M, Erenbourg L, Paganelli M, Di Carlo V. Fat absorption and gastroenteric pH profile in postsurgical pancreatic insufficiency: role of the association of H2-rcceptor antagonists with pancreatic enzymes. Pancreas 1993; 8: 494-8.
    • (1993) Pancreas , vol.8 , pp. 494-498
    • Braga, M.1    Zerbi, A.2    Malesci, A.3    Dal Cin, S.4    Valentin, A.5    Tacconi, M.6    Erenbourg, L.7    Paganelli, M.8    Di Carlo, V.9
  • 21
    • 0023001005 scopus 로고
    • Omeprazole as adjunct to enzyme replacement in severe pancreatic insufficiency
    • Lamers CB, Jansen JB. Omeprazole as adjunct to enzyme replacement in severe pancreatic insufficiency. Br Med J 1986; 293: 994.
    • (1986) Br Med J , vol.293 , pp. 994
    • Lamers, C.B.1    Jansen, J.B.2
  • 22
    • 0023006865 scopus 로고
    • Therapy of pancreatogenic steatorrhoea: Does acid protection of pancreatic enzymes offer any advantage?
    • Lankisch PG, Lembcke B, Goke B, Creutzfeldt W. Therapy of pancreatogenic steatorrhoea: does acid protection of pancreatic enzymes offer any advantage? Z Gastroenterol 1986; 24: 753-7.
    • (1986) Z Gastroenterol , vol.24 , pp. 753-757
    • Lankisch, P.G.1    Lembcke, B.2    Goke, B.3    Creutzfeldt, W.4
  • 23
    • 0019292872 scopus 로고
    • Effectiveness of cimetidine as an adjunct to supplemental pancreatic enzymes in patients with cystic fibrosis
    • Hubbard VS, Dünn GD, Lester LA. Effectiveness of cimetidine as an adjunct to supplemental pancreatic enzymes in patients with cystic fibrosis. Am J Clin Nutr 1980; 33: 2281-6.
    • (1980) Am J Clin Nutr , vol.33 , pp. 2281-2286
    • Hubbard, V.S.1    Dünn, G.D.2    Lester, L.A.3
  • 24
    • 0019209252 scopus 로고
    • Effect of cimetidine and sodium bicarbonate on pancreatic replacement therapy in cystic fibrosis
    • Durie PR, Bell L, Linton W, Corey ML, Forstner GG. Effect of cimetidine and sodium bicarbonate on pancreatic replacement therapy in cystic fibrosis. Gut 1980; 21: 778-86.
    • (1980) Gut , vol.21 , pp. 778-786
    • Durie, P.R.1    Bell, L.2    Linton, W.3    Corey, M.L.4    Forstner, G.G.5
  • 25
    • 0018415148 scopus 로고
    • The effect of cimetidine on maldigestion in cystic fibrosis
    • Cox KL, Isenberg JN, Osher AB, Dooley RR.r The effect of cimetidine on maldigestion in cystic fibrosis. J Pediatr 1979; 94: 488-92.
    • (1979) J Pediatr , vol.94 , pp. 488-492
    • Cox, K.L.1    Isenberg, J.N.2    Osher, A.B.3    Dooley, R.R.4
  • 26
    • 0019404760 scopus 로고
    • Comparative study of varying regimens to improve steatorrhoea and creatorrhoea in cystic fibrosis: Effectiveness of an enteric-coated preparation with and without antacids and cimetidine
    • Gow R, Bradbear R, Francis P, Shepherd R. Comparative study of varying regimens to improve steatorrhoea and creatorrhoea in cystic fibrosis: Effectiveness of an enteric-coated preparation with and without antacids and cimetidine. Lancet 1981; 2: 1071-1.
    • (1981) Lancet , vol.2 , pp. 1071-1071
    • Gow, R.1    Bradbear, R.2    Francis, P.3    Shepherd, R.4
  • 27
    • 0017695992 scopus 로고
    • Comparative effects of antacids, cimetidine and enteric coating on the therapeutic response to oral enzymes in severe pancreatic insufficiency
    • Regan FT, Malagelada JR, DiMagno EP, Glanzman SL, Go VL. Comparative effects of antacids, cimetidine and enteric coating on the therapeutic response to oral enzymes in severe pancreatic insufficiency. N Engl J Med 1977: 297: 854-8.
    • (1977) N Engl J Med , vol.297 , pp. 854-858
    • Regan, F.T.1    Malagelada, J.R.2    Dimagno, E.P.3    Glanzman, S.L.4    Go, V.L.5
  • 28
    • 0027397856 scopus 로고
    • Improvement of fecal fat excretion after addition of omeprazole to pancrease in cystic fibrosis is related to residual exocrine function of the pancreas
    • Heijerman HG, Lamers CB, Bakker W, Dijkman JH. Improvement of fecal fat excretion after addition of omeprazole to pancrease in cystic fibrosis is related to residual exocrine function of the pancreas. Dig Dis Sei 1993; 38: 1-6.
    • (1993) Dig Dis Sei , vol.38 , pp. 1-6
    • Heijerman, H.G.1    Lamers, C.B.2    Bakker, W.3    Dijkman, J.H.4
  • 29
    • 0025963340 scopus 로고
    • Omeprazole enhances the efficacy of pancreatin (pancrease) in cystic fibrosis
    • Heijerman HG, Lamers CB, Bakker W. Omeprazole enhances the efficacy of pancreatin (pancrease) in cystic fibrosis. Ann Intern Med 1991; 114: 200-1.
    • (1991) Ann Intern Med , vol.114 , pp. 200-201
    • Heijerman, H.G.1    Lamers, C.B.2    Bakker, W.3
  • 30
    • 0028292151 scopus 로고
    • Comparative effects of adjuvant cimetidine and omeprazole during pancreatic enzyme replacement therapy
    • Bruno MJ, Rauws EA, Hoek FJ, Tytgat GN. Comparative effects of adjuvant cimetidine and omeprazole during pancreatic enzyme replacement therapy. Dig Dis Sei 1994; 39: 988-92.
    • (1994) Dig Dis Sei , vol.39 , pp. 988-992
    • Bruno, M.J.1    Rauws, E.A.2    Hoek, F.J.3    Tytgat, G.N.4
  • 31
    • 0024590393 scopus 로고
    • Pancreatic enzyme replacement therapy. Importance of gastric acid secretion, H2-antagonists, and enteric coating
    • Marotta F, O'Keefe SJ, Marks IN, Girdwood A, Young G. Pancreatic enzyme replacement therapy. Importance of gastric acid secretion, H2-antagonists, and enteric coating. Dig Dis Sei 1989:34:456-61.
    • (1989) Dig Dis Sei , vol.34 , pp. 456-461
    • Marotta, F.1    O'Keefe, S.J.2    Marks, I.N.3    Girdwood, A.4    Young, G.5
  • 32
    • 0020335238 scopus 로고
    • Does mixing pancreatic enzyme microspheres (Pancrease) with food damage the enteric coating?
    • Sackman JVV, Smith KE, Graham DY. Does mixing pancreatic enzyme microspheres (Pancrease) with food damage the enteric coating? J Pediatr Gastroenterol Nutr 1982; 1: 333-5.
    • (1982) J Pediatr Gastroenterol Nutr , vol.1 , pp. 333-335
    • Sackman, J.V.V.1    Smith, K.E.2    Graham, D.Y.3
  • 33
    • 0029885908 scopus 로고    scopus 로고
    • Pancreatin preparations used in the treatment of cystic fibrosis-lipase content and in vitro release
    • Walters MP, Littlewood JM. Pancreatin preparations used in the treatment of cystic fibrosis-lipase content and in vitro release. Aliment Pharmacol Ther 1996; 10: 433-40.
    • (1996) Aliment Pharmacol Ther , vol.10 , pp. 433-440
    • Walters, M.P.1    Littlewood, J.M.2
  • 34
    • 0025346130 scopus 로고
    • Treatment failure after substitution of generic pancrelipase capsules. Correlation with in vitro lipase activity
    • Hendeles L, Dorf A, Stecenko A, Weinberger M. Treatment failure after substitution of generic pancrelipase capsules. Correlation with in vitro lipase activity. J Am Med Assoc 1990; 263: 2459-61.
    • (1990) J Am Med Assoc , vol.263 , pp. 2459-2461
    • Hendeles, L.1    Dorf, A.2    Stecenko, A.3    Weinberger, M.4
  • 35
    • 0029023003 scopus 로고
    • Stated versus actual lipase activity in pancreatic enzyme supplements: Implications for clinical use
    • O'Hare MM, McMaster C, Dodge JA. Stated versus actual lipase activity in pancreatic enzyme supplements: implications for clinical use. J Pediatr Gastroenterol Nutr 1995; 21: 59-63.
    • (1995) J Pediatr Gastroenterol Nutr , vol.21 , pp. 59-63
    • O'Hare, M.M.1    McMaster, C.2    Dodge, J.A.3
  • 36
    • 0021245082 scopus 로고
    • Proteolytic inactivation of lipase as a possible cause of the uneven results obtained with enzyme substitution in pancreatic insufficiency
    • Pap A, Varro V. Proteolytic inactivation of lipase as a possible cause of the uneven results obtained with enzyme substitution in pancreatic insufficiency. Hepatogastroenterol 1984: 31: 47-50.
    • (1984) Hepatogastroenterol , vol.31 , pp. 47-50
    • Pap, A.1    Varro, V.2
  • 37
    • 0028335979 scopus 로고
    • High strength pancreatic exocrine enzyme capsules associated with colonie strictures in patients with cystic fibrosis: 'more is not necessarily better'
    • Lebenthal E. High strength pancreatic exocrine enzyme capsules associated with colonie strictures in patients with cystic fibrosis: 'more is not necessarily better'. J Pediatr Gastroenterol Nutr 1994; 18: 423-5.
    • (1994) J Pediatr Gastroenterol Nutr , vol.18 , pp. 423-425
    • Lebenthal, E.1
  • 38
    • 0028913042 scopus 로고
    • Ulcerative type of colitis associated with the use of high strength pancreatic enzyme supplements in cystic fibrosis
    • Abiin DS, Ziegler M. Ulcerative type of colitis associated with the use of high strength pancreatic enzyme supplements in cystic fibrosis. Pediatr Radiol 1995:25:113-6.
    • (1995) Pediatr Radiol , vol.25 , pp. 113-116
    • Abiin, D.S.1    Ziegler, M.2
  • 40
  • 42
    • 0028117818 scopus 로고
    • Comparison of a high lipase pancreatic enzyme extract with a regular pancreatin preparation in adult cystic fibrosis patients
    • Can KH, Heijerman HG, Gcus VVP, Bakker W, Lamers CB. Comparison of a high lipase pancreatic enzyme extract with a regular pancreatin preparation in adult cystic fibrosis patients. Aliment Pharmacol Ther 1994; 8: 603-7.
    • (1994) Aliment Pharmacol Ther , vol.8 , pp. 603-607
    • Can, K.H.1    Heijerman, H.G.2    Gcus, V.V.P.3    Bakker, W.4    Lamers, C.B.5
  • 44
    • 0023727658 scopus 로고
    • Critical examination of therapeutic efficacy of a pH-sensitive enteric-coated pancreatic enzyme preparation in treatment of exocrine pancreatic insufficiency secondary to cystic fibrosis
    • Dutta SK, Hubbard VS. Appler M. Critical examination of therapeutic efficacy of a pH-sensitive enteric-coated pancreatic enzyme preparation in treatment of exocrine pancreatic insufficiency secondary to cystic fibrosis. Dig Dis Sei 1988; 33: 1237-44.
    • (1988) Dig Dis Sei , vol.33 , pp. 1237-1244
    • Dutta, S.K.1    Hubbard, V.S.2    Appler, M.3
  • 45
    • 0018362120 scopus 로고
    • Postprandial gastric function in pancreatic insufficiency
    • Regan PT, Malagelada JR, DiMagno EP, Go VL. Postprandial gastric function in pancreatic insufficiency. Gut 1979; 20: 249-54.
    • (1979) Gut , vol.20 , pp. 249-254
    • Regan, P.T.1    Malagelada, J.R.2    Dimagno, E.P.3    Go, V.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.