A role for the androgen receptor in collagen content of the skin

Journal of Investigative Dermatology

Volumn 123, Issue 6, 2004, Pages 1052-1056

  Markova, Marina S ^a   Zeskand, Joseph ^a   McEntee, Benjamin ^a   Rothstein, Jay ^a   Jimenez, Sergio A ^a   Siracusa, Linda D ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Androgen receptor; Collagen; Gender; Hydroxyproline; Mouse; Skin

Indexed keywords

ANDROGEN RECEPTOR; COLLAGEN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PUBERTY; RECEPTOR GENE; REGULATORY MECHANISM; WILD TYPE; X CHROMOSOME LINKAGE;

EID: 9744280477     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2004.23494.x     Document Type: Article

References (32)

1. Chang C, Saltzman A, Yeh S, et al: Androgen receptor: An overview. Crit Rev Eukaryot Gene Expr 5:97-125, 1995
2. Charest NJ, Zhou Z, Lubahn DB, Olsen K, Wilson EM, French FS: A frameshift mutation destabilizes androgen receptor messenger RNA in the tfm mouse. Mol Endocrinol 5:573-581, 1991
3. Christner PJ, Peters J, Hawkins D, Siracusa LD, Jimenez SJ: The tight skin 2 mouse: An animal model of scleroderma displaying cutaneous fibrosis and mononuclear cell infiltration. Arthritis Rheum 38:1791-1798, 1995
4. Dickerson JWT, John PMV: The effect of sex and site on the composition of skin in the rat and mouse. Biochem J 92:364-368, 1964
5. Dunn JF, Wilson JD: Developmental study of androgen responsiveness in the submandibular gland of the mouse. Endocrinology 96:1571-1578, 1975
6. Esterly NB, McKusick VA: Stiff skin syndrome. Pediatrics 47:360-369, 1971
7. Freund JE: Modern Elementary Statistics. Englewood Cliffs, NJ: Prentice-Hall, 1988
8. Gao J, Isaacs JT: Development of an androgen receptor-null model for identifying the initiation site for androgen stimulation of proliferation and suppression of programmed (apoptotic) death of PC-82 human prostate cancer cells. Cancer Res 58:3299-3306, 1998
9. Gaspar M-L, Meo T, Bourgarel P, Guenet J-L, Tosi M: A single base deletion in the Tfm androgen receptor gene creates a short-lived messenger RNA that directs internal translation initiation. Proc Natl Acad USA 88:8606-8610, 1991
10. Gendimenico GJ, Mack VJ, Siock PA, Mezick JA: Topical estrogens: Their effects on connective tissue synthesis in hairless mouse skin. Arch Dermatol Res 294:231-236, 2002
11. Goldstein JL, Wilson JD: Studies on the pathogenesis of the pseudohermatophrodism in the mouse with testicular feminization. J Clin Invest 51:1647-1658, 1972
12. Jablonska S, Schubert H, Kikuchi I: Congenital fascial dystrophy: Stiff skin syndrome - a human counterpart of the tight-skin mouse. J Am Acad Dermatol 21:943-950, 1989
13. Jimenez SA, Hitraya E, Varga J: Pathogenesis of scleroderma. Collagen. Rheum Dis Clin North Am 22:647-674, 1996
14. Jimenez SA, Millan A, Bashey RI: Scleroderma-like alterations in collagen metabolism occurring in the TSK (tight skin) mouse. Arthritis Rheum 27:180-185, 1984
15. Kalluri R: Basement membranes: Structure, assembly and role in tumour angiogenesis. Nature Reviews Cancer 3:422-433, 2003
16. Kivirikko KI, Laitinen O, Prockop DJ: Modifications of specific assay for hydroxyproline in urine. Anal Biochem 19:249-255, 1967
17. Kwan G, Neugarten J, Sherman M, Ding Q, Fotadar U, Lei J, Silbiger S: Effects of sex hormones on mesangial cell proliferation and collagen synthesis. Kidney Int 50:1173-1179, 1996
18. Liang T, Hoyer S, Yu R, Soltani K, Lorincz AL, Hiipakka RA, Liao S: Immunocytochemical localization of androgen receptors in human skin using monoclonal antibodies against the androgen receptor. J Invest Dermatol 100:663-666, 1993
19. Liegibel UM, Sommer U, Boercsoek I, et al: Androgen receptor isoforms AR-A and AR-B display functional differences in cultured human bone cells and genital skin fibroblasts. Steroids 68:1179-1187, 2003
20. Lyon MF, Hawkes SG: X-linked gene for testicular feminization in the mouse. Nature 227:1217-1219, 1970
21. Murphy L, Jeffcoate IA, O'Shaughnessy PJ: Abnormal Leydig cell development at puberty in the androgen-resistant Tfm mouse. Endocrinology 135:1372-1377, 1994
22. Myllyharju J, Kivirikko KI: Collagens and collagen-related diseases. Annals Med 33:7-21, 2001
23. 2 preferentially increase luciferase levels in bone of mice harboring a luciferase transgene controlled by elements of the Pro-α1(I) collagen promoter. Bone 26:27-32, 2000
24. Ottani V, Martini D, Franchi M, Ruggeri A, Raspanti M: Hierarchical structures in fibrillar collagens. Micron 33:587-596, 2002
25. Ottani V, Raspanti M, Ruggeri A: Collagen structure and functional implications. Micron 32:251-260, 2001
26. Ozasa H, Tominaga T, Nishimura T, Takeda T: Evidence for receptor-dependent response to dihydrotestosterone in cultured human fibroblasts. Endokrinologie 77:129-136, 1981
27. Prockop DJ, Underfriend S: A specific method for analysis of hydroxyproline in tissues and urine. Anal Biochem 1:228-239, 1960
28. Raine-Fenning NJ, Brincat MP, Muscat-Baron Y: Skin aging and menopause: Implications for treatment. Am J Clin Dermatol 4:371-378, 2003
29. Silver LM: Mouse Genetics Concepts and Applications. New York: Oxford University Press, 1995
30. Siracusa LD, McGrath R, Ma Q, et al: A tandem duplication within the fibrillin 1 gene is associated with the mouse Tight skin mutation. Genome Res 6:300-313, 1996
31. Tzaphlidou M: Diameter distributions of collagenous tissues in relation to sex. A quantitative ultrastructural study. Micron 32:333-336, 2001
32. Yonehara K, Suzuki M, Yamanouchi K, Nishihara M: Expression analyses of sex steroid-regulated genes in neonatal rat hypothalamus. J Repro Develop 49:547-552, 2003