Observing tumor vascularity noninvasively using magnetic resonance imaging

Image Analysis and Stereology

Volumn 21, Issue 2, 2002, Pages 107-113

  Haacke, Mark E ^a   Herigault, Gwen ^a   Kido, Daniel ^b   Tong, Karen ^b   Obenaus, Andre ^b   Yu, Yingjian ^b   Reichenbach, Juergen R ^c  

^a Magnetic Resonance Imaging Institute for Biomedical Research   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Brain vasculature; Susceptibility weighted images; Tumor identification; Venous system

Indexed keywords

EID: 9744225389     PISSN: 15803139     EISSN: 18545165     Source Type: Journal    
DOI: 10.5566/ias.v21.p107-113     Document Type: Article

References (18)

1. Al-Hallaq HA, River JN, Zamora M, Oikawa H, Karczmar GS (1998). Correlation of magnetic resonance and oxygen microelectrode measurements of carbogen-induced changes in tumor oxygenation. Int J Radiat Oncol Biol Phys 41:151-60.
2. Belliveau JW et al. (1991). Functional mapping of the human visual cortex by magnetic resonance imaging. Science 254:716-9.
3. Bergers G, Javaherian K, Lo KM, Folkman J, Hanahan D (1999). Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science 284:808-12.
4. Carmeliet P et al. (1998). Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 394:485-90.
5. Cheng YCN, Cheng YN, Haacke EM (2001). Predicting BOLD Signal Changes as a Function of Blood Volume Fraction and Resolution. NMR in Biomedicine 14:468-77.
6. Haacke EM, et al. (1997). In vivo measurement of blood oxygen saturation using magnetic resonance imaging: A direct validation of the blood oxygen leveldependent concept in functional brain imaging. Human Brain Mapping 5:341-6.
7. Haacke EM, Lai S, Yablonskiy D, Lin W (1995). In vivo validation of the BOLD mechanism: a review of signal changes in gradient echo functional MRI in the presence of flow. International Journal of Imaging Syst Technology 6:153-63.
8. Jürgen R, Reichenbach JR, Haacke EM (2001). Highresolution BOLD venographic imaging: a window into brain function. NMR in Biomedicine 14:453-67.
9. Lee BC, et al. (1999). MR high-resolution bold oxygenation level-dependent venography of occult (low-flow) vascular leisons. Am J Neuroradiol 20:1239-42.
10. Lin W, et al. (1999). Improving high-resolution MR BOLD venographic imaging using a T1 reducing contrast agent. JMRI 10:118-23.
11. McSheehy MJ et al. (1998). Carbogen breathing increases 5-fluorouracil uptake and cytotoxicity in hypoxic murine RIF-1 tumors: a magnetic resonance study in vivo. Cancer Research 58:1185-94.
12. Ogawa S, Lee T, Kay AR, Tank DW (1990). Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci 87:9868-72.
13. Reichenbach JR et al. (1998). High-resolution venography of the brain using magnetic resonance imaging. Magnetic Resonance Materials in Biology, Physics and Medicine 6:62-9.
14. Reichenbach JR, Barth M, Haacke EM, Klarhöfer M, Kaiser WA, Moser E (2000). High-Resolution MR Venography at 3 Tesla. JCAT 24:949-57.
15. Reichenbach JR, Venkatesan R, Schillinger DJ, Kido DK, Haacke EM (1997). Small vessels in the human brain: MR venography with deoxyhemoglobin as an intrinsic contrast agent. Radiology 204:272-7.
16. Salamon G, Huang YP (1976). Radiologic anatomy of the brain. Berlin: Springer-Verlag.
17. Schad L (2001). Improved target volume characterization in stereotactic treatment planning of brain lesions by using high-resolution BOLD MR-venography. NMR in Biomedicine 14:478-83.
18. Weisskoff RM, Kiihne S (1992). MRI susceptometry: image-based measurement of absolute susceptibility of MR contrast agents and human blood. Magn Reson in Med 24:375-83.