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Volumn 13, Issue 1, 2005, Pages 131-139

The novel pyrimidine and purine derivatives of l-ascorbic acid: Synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation

(10) Gazivoda, Tatjana a Plevnik, Miha b Plavec, Janez b Kraljević, Sandra c Kralj, Marijeta c Pavelić, Krešimir c Balzarini, Jan d Clercq, Erik De d Mintas, Mladen a Raić Malić, Silvana a

a UNIVERSITY OF ZAGREB (Croatia)

b NATIONAL INSTITUTE OF CHEMISTRY (Slovenia)

c RUDER BO KOVI INSTITUTE (Croatia)

d REGA INSTITUTE FOR MEDICAL RESEARCH (Belgium)

Author keywords

Antiviral activity; Apoptosis; Cytostatic activity; E and Z isomers; Pyrimidine and purine derivatives of l ascorbic acid

Indexed keywords

ANTIVIRUS AGENT; ASCORBIC ACID; BENZENE; CYTOSTATIC AGENT; FLUOROURACIL; HYDROXYL GROUP; LACTONE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CULTURE; CELL STRAIN MCF 7; CHEMICAL BOND; CONTROLLED STUDY; CYTOSTASIS; DEBENZYLATION; DERIVATIZATION; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; HYBRID CELL; IC 50; PROTON NUCLEAR MAGNETIC RESONANCE; RING OPENING; SPECTRAL SENSITIVITY; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; T LYMPHOCYTE;

ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; ASCORBIC ACID; CARBON ISOTOPES; CELL LINE, TUMOR; DRUG EVALUATION, PRECLINICAL; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PROTONS; PURINES; PYRIMIDINES; SPECTROPHOTOMETRY, ULTRAVIOLET;

MINK CELL FOCUS-FORMING VIRUS;

EID: 9644307888 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2004.09.052 Document Type: Article

Times cited : (36)

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