Development of a novel chiral spiro ligand bearing oxazoline

Tetrahedron Asymmetry

Volumn 15, Issue 23, 2004, Pages 3693-3697

  Kato, Takahiro ^a   Marubayashi, Kazuyoshi ^a   Takizawa, Shinobu ^a   Sasai, Hiroaki ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL DERIVATIVE; COPPER DERIVATIVE; LIGAND; N BROMOSUCCINIMIDE; OXAZOLINE DERIVATIVE; SPIRO COMPOUND;

ARTICLE; CATALYST; CHEMICAL STRUCTURE; CHIRALITY; COMPLEX FORMATION; CYCLIZATION; ENANTIOMER; ENANTIOSELECTIVITY; PRIORITY JOURNAL; PROCESS DEVELOPMENT; REACTION ANALYSIS; RING CLOSING METATHESIS; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 9644276845     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetasy.2004.09.037     Document Type: Article

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38. 4 and concentrated. The residue was purified by silica gel column chromatography (ethyl acetate/hexane = 1:8) to afford the product in 62% yield with 84% ee. The enantiomeric excess of the products was determined by HPLC analysis using a chiral stationary phase column (Daicel Chiralpak AS, hexane/i-PrOH = 9:1, flow rate = 0.5 mL/min)
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