메뉴 건너뛰기




Volumn 23, Issue 10, 2004, Pages 1625-1637

Synthesis and antiviral evaluation of D4T analogues with a spacer arm between glucidic and base moieties

Author keywords

Glycosylation; HIV; Microwave; Nucleosides; Selective deprotection

Indexed keywords

1 [2 (2',3' DIDEHYDRO 2',3' DIDEOXY BETA DEXTRO RIBOFURANOSYLOXY)ETHYL]THYMINE; 1 [3 (2',3' DIDEHYDRO 2',3' DIDEOXY BETA DEXTRO RIBOFURANOSYLOXY)PROPYL]THYMINE; 1 [4 (2',3' DIDEHYDRO 2',3' DIDEOXY BETA DEXTRO RIBOFURANOSYLOXY)BUTYL]THYMINE; ANTIVIRUS AGENT; CARBOHYDRATE DERIVATIVE; STAVUDINE; UNCLASSIFIED DRUG;

EID: 9644254200     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-200031457     Document Type: Article
Times cited : (7)

References (16)
  • 1
    • 0027435230 scopus 로고
    • The linking chain length in bridged aldehyde-substituted pyridinium dimers modulates a slow reversible binding that affects supercoiling of plasmid DNA
    • Dodin, G.; Kühnel, S.M.; Demersman, P.; Kotzyba, J. The linking chain length in bridged aldehyde-substituted pyridinium dimers modulates a slow reversible binding that affects supercoiling of plasmid DNA. Anticancer Drug Des. 1993, 8 (5), 361-368.
    • (1993) Anticancer Drug Des. , vol.8 , Issue.5 , pp. 361-368
    • Dodin, G.1    Kühnel, S.M.2    Demersman, P.3    Kotzyba, J.4
  • 3
    • 0027462696 scopus 로고
    • Base-modified oligodeoxynucleotides. I. Effect of 5-alkyl, 5-(1-alkenyl) and 5-(1-alkynyl) substitution of the pyrimidines on duplex stability and hydrophobicity
    • Sagi, J.; Smezo, A.; Ebinger, K.; Szabolcs, A.; Sagi, G.; Ruff, E.; Otvos, L. Base-modified oligodeoxynucleotides. I. Effect of 5-alkyl, 5-(1-alkenyl) and 5-(1-alkynyl) substitution of the pyrimidines on duplex stability and hydrophobicity. Tetrahedron Lett. 1993, 34 (13), 2191-2194.
    • (1993) Tetrahedron Lett. , vol.34 , Issue.13 , pp. 2191-2194
    • Sagi, J.1    Smezo, A.2    Ebinger, K.3    Szabolcs, A.4    Sagi, G.5    Ruff, E.6    Otvos, L.7
  • 5
    • 0014422472 scopus 로고
    • Synthetic spectroscopic models related to coenzymes and base pairs. II. Evidence for intramolecular base-base interactions in dinucleotide analogs
    • Browne, D.T.; Eisingerand, F.J.; Leonard, N.J. Synthetic spectroscopic models related to coenzymes and base pairs. II. Evidence for intramolecular base-base interactions in dinucleotide analogs. J. Am. Chem. Soc. 1968, 90 (26), 7302-7323.
    • (1968) J. Am. Chem. Soc. , vol.90 , Issue.26 , pp. 7302-7323
    • Browne, D.T.1    Eisingerand, F.J.2    Leonard, N.J.3
  • 6
    • 0001392010 scopus 로고
    • Search for a simpler synthetic model system for intramolecular 1,3-dipolar cycloaddition to the 5,6-double bond of a pyrimidine nucleoside
    • Sazaki, T.; Minamoto, V.; Susuki, T.; Yamashita, S. Search for a simpler synthetic model system for intramolecular 1,3-dipolar cycloaddition to the 5,6-double bond of a pyrimidine nucleoside. Tetrahedron 1980, 36 (7), 865-870.
    • (1980) Tetrahedron , vol.36 , Issue.7 , pp. 865-870
    • Sazaki, T.1    Minamoto, V.2    Susuki, T.3    Yamashita, S.4
  • 7
    • 0343578816 scopus 로고
    • 5-Alkoxy-methyl-1-hydroxyalkyluracils with potential anti-HIV activity
    • Adbel-Megied, A.E.S.; Motawia, M.S.; Pedersen, E.B.; Nielsen, C.M. 5-Alkoxy-methyl-1-hydroxyalkyluracils with potential anti-HIV activity. Heterocycles 1992, 34 (4), 713-722.
    • (1992) Heterocycles , vol.34 , Issue.4 , pp. 713-722
    • Adbel-Megied, A.E.S.1    Motawia, M.S.2    Pedersen, E.B.3    Nielsen, C.M.4
  • 8
  • 9
    • 0035813242 scopus 로고    scopus 로고
    • A tentative rationalization of microwave effects in organic synthesis according to the reaction medium, and mechanistic considerations
    • Perreux, L.; Loupy, A. A tentative rationalization of microwave effects in organic synthesis according to the reaction medium, and mechanistic considerations. Tetrahedron 2001, 57 (45), 9199-9223.
    • (2001) Tetrahedron , vol.57 , Issue.45 , pp. 9199-9223
    • Perreux, L.1    Loupy, A.2
  • 10
    • 0038867698 scopus 로고    scopus 로고
    • Solvent-free synthesis of decyl D-glycopyranosides under focused microwave irradiation
    • Limousin, C.; Cléophax, J.; Petit, A.; Loupy, A.; Lukacs, G. Solvent-free synthesis of decyl D-glycopyranosides under focused microwave irradiation. J. Carbohydr. Chem. 1997, 16 (3), 327-342.
    • (1997) J. Carbohydr. Chem. , vol.16 , Issue.3 , pp. 327-342
    • Limousin, C.1    Cléophax, J.2    Petit, A.3    Loupy, A.4    Lukacs, G.5
  • 11
    • 7344258577 scopus 로고
    • Preparation of 1,2-trans-glycosides in the presence of stannic chloride
    • Hannessian, S.; Banoub, J. Preparation of 1,2-trans-glycosides in the presence of stannic chloride. Methods Carbohydr. Chem. 1980, 8, 243-245.
    • (1980) Methods Carbohydr. Chem. , vol.8 , pp. 243-245
    • Hannessian, S.1    Banoub, J.2
  • 12
    • 0024554252 scopus 로고
    • General syntheses of 2′,3′-dideoxynucleosides and 2′,3′-didehydro-2′,3′-dideoxynucleosides
    • Chu, C.K.; Bhadti, V.S.; Doboszewski, B. General syntheses of 2′,3′-dideoxynucleosides and 2′,3′-didehydro-2′, 3′-dideoxynucleosides. J. Org. Chem. 1989, 54 (9), 2217-2225.
    • (1989) J. Org. Chem. , vol.54 , Issue.9 , pp. 2217-2225
    • Chu, C.K.1    Bhadti, V.S.2    Doboszewski, B.3
  • 13
    • 0000215322 scopus 로고
    • A mild procedure for the conversion of 1,2-diols to olefins
    • Corey, E.J.; Hopkins, P.B. A mild procedure for the conversion of 1,2-diols to olefins. Tetrahedron Lett. 1982, 23 (19), 1979-1982.
    • (1982) Tetrahedron Lett. , vol.23 , Issue.19 , pp. 1979-1982
    • Corey, E.J.1    Hopkins, P.B.2
  • 14
    • 0028124660 scopus 로고
    • Bicyclic imidazo derivatives, a new class of highly selective inhibitors for the human immunodeficiency virus type I
    • Moog, C.; Wick, A.; Le Ber, P.; Kirn, A.; Aubertin, A.M. Bicyclic imidazo derivatives, a new class of highly selective inhibitors for the human immunodeficiency virus type I. Antivir. Res. 1994, 24 (4), 275-288.
    • (1994) Antivir. Res. , vol.24 , Issue.4 , pp. 275-288
    • Moog, C.1    Wick, A.2    Le Ber, P.3    Kirn, A.4    Aubertin, A.M.5
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mossman, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mossman, T.1
  • 16
    • 0002607770 scopus 로고
    • 50, synergism, antagonism, low-dose risk, receptor binding and enzyme kinetics
    • Elsevier-Biosoft, Elsevier Science Publishers: Cambridge, UK
    • 50, synergism, antagonism, low-dose risk, receptor binding and enzyme kinetics. In Computer Software Apple II Series and IBM-PC and Instruction Manual; Elsevier-Biosoft, Elsevier Science Publishers: Cambridge, UK, 1985; 19-28.
    • (1985) Computer Software Apple II Series and IBM-PC and Instruction Manual , pp. 19-28
    • Chou, J.1    Chou, T.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.