Clonal xenobiotic resistance during pollution-induced toxic injury and hepatocellular carcinogenesis in liver of female flounder (Platichthys flesus (L.))

Acta Histochemica

Volumn 106, Issue 2, 2004, Pages 155-170

  Koehler, Angela ^a   Alpermann, Tilmann ^a   Lauritzen, Bjarne ^a   Van Noorden, Cornelis J F ^b  

^a ALFRED WEGENER INSTITUTE FOR POLAR AND MARINE RESEARCH   (Germany)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Carcinogenesis; CYP450; Elbe; Flatfish; G6PDH; GST; Lysosomes; Multidrug xenobiotic resistance; North Sea; P pg; Pollution

Indexed keywords

BIOLOGICAL ORGANS; CARCINOGENS; CELL CULTURE; CELLS; MEDICAL PROBLEMS; METABOLISM; MUTAGENESIS; TOXICITY; TUMORS; WATER POLLUTION;

CARCIONOGENESIS; CYP450; ELBE; FLATFISH; G6PDH; GST; LYSOSOMES; MULTIDRUG/XENOBIOTIC RESISTANCE; NORTH SEA; P-PG;

CLONING;

CYTOCHROME P450 1A1; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE TRANSFERASE; GLYCOPROTEIN P; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; CARCINOGEN; ENZYME; TUMOR MARKER; XENOBIOTIC AGENT;

ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CANCER GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; EPIGENETICS; FEMALE; FLOUNDER; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; LIVER INJURY; LONG TERM EXPOSURE; LYSOSOME; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; UPREGULATION; XENOBIOTIC METABOLISM; ADAPTATION; ADENOMA; ANIMAL; ANIMAL DISEASE; BASOPHIL; CELL TRANSFORMATION; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ENZYMOLOGY; EOSINOPHIL; FISH DISEASE; GENE EXPRESSION REGULATION; LIVER; LIVER TUMOR; MALE; METABOLISM; PATHOLOGY; SEX DIFFERENCE; WATER POLLUTANT;

MAMMALIA; PLATICHTHYS FLESUS; PLEURONECTIFORMES; PLEURONECTOIDEI;

ADAPTATION, PHYSIOLOGICAL; ADENOMA; ANIMALS; BASOPHILS; CARCINOGENS, ENVIRONMENTAL; CELL TRANSFORMATION, NEOPLASTIC; ENZYMES; EOSINOPHILS; FEMALE; FISH DISEASES; FLOUNDER; GENE EXPRESSION REGULATION, NEOPLASTIC; LIVER; LIVER NEOPLASMS; MALE; SEX FACTORS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION; WATER POLLUTANTS, CHEMICAL; XENOBIOTICS;

EID: 9644253397     PISSN: 00651281     EISSN: 16180372     Source Type: Journal    
DOI: 10.1016/j.acthis.2004.02.002     Document Type: Article

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