The involvement of cytochrome P450 peroxidase in the metabolic bioactivation of cumene hydroperoxide by isolated rat hepatocytes

Chemical Research in Toxicology

Volumn 9, Issue 6, 1996, Pages 924-931

  Reza Anari, M ^a   Khan, Sumsullah ^a   O'Brien, Peter J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CUMENE HYDROPEROXIDE; CYTOCHROME P450 REDUCTASE;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DAMAGE; CYTOTOXICITY; DETOXIFICATION; LIPID PEROXIDATION; LIVER METABOLISM; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALS; BENZENE DERIVATIVES; BIOTRANSFORMATION; CELL MEMBRANE; CHLORZOXAZONE; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DEFEROXAMINE; GLUTATHIONE PEROXIDASE; IMIDAZOLES; LIPID PEROXIDATION; LIVER; MALE; OXIDANTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 9544245931     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx950188d     Document Type: Article

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