Distinct classes of glyoxalase I: Metal specificity of the Yersinia pestis, Pseudomonas aeruginosa and Neisseria meningitidis enzymes

Biochemical Journal

Volumn 384, Issue 1, 2004, Pages 111-117

  Sukdeo, Nicole ^a   Clugston, Susan L ^a,b   Daub, Elisabeth ^a   Honek, John F ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b PFIZER INC   (United States)

Author keywords

Glyoxalase; Lyase; Metal activation; Metalloenzyme; Nickel; Zinc

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; BACTERIA; CATALYSIS; DERIVATIVES; ESCHERICHIA COLI; ESTERS;

GLYOXALASE; METAL ACTIVATION; METAL LIGANDS; METALLOENZYMES;

ENZYMES;

BACTERIAL ENZYME; GLYOXALASE;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ANALYSIS; ENZYME SPECIFICITY; ESCHERICHIA COLI; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PUTIDA; SACCHAROMYCES CEREVISIAE; YERSINIA PESTIS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CADMIUM; CLONING, MOLECULAR; COBALT; DNA, BACTERIAL; ENZYME ACTIVATION; KINETICS; LACTOYLGLUTATHIONE LYASE; MANGANESE; METALS; MOLECULAR SEQUENCE DATA; NEISSERIA MENINGITIDIS; NICKEL; PSEUDOMONAS AERUGINOSA; SEQUENCE ALIGNMENT; YERSINIA PESTIS; ZINC;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; HOMO SAPIENS; NEGIBACTERIA; NEISSERIA MENINGITIDIS; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PUTIDA; SACCHAROMYCES CEREVISIAE; YERSINIA PESTIS;

EID: 9444245016     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041006     Document Type: Article

References (39)

1. Neuberg, C. (1931) The destruction of lactic aldehyde and methylglyoxal by animal organisms. Biochem. Z. 49, 502-506
2. Dakin, H. D. and Dudley, H. W. (1913) An enzyme concerned with the formation of hydroxy acids from ketonic aldehydes. J. Biol. Chem. 14, 155-157
3. Thornalley, P. J. (2003) Glyoxalase I - structure, function and a critical role in the enzymatic defence against glycation. Biochem. Soc. Trans. 31, 1343-1348
4. Becker, K., Rahlfs, S., Nickel, C. and Schirmer, R. H. (2003) Glutathione - functions and metabolism in the malarial parasite Plasmodium falciparum. Biol. Chem. 384, 551-566
5. Rose, I. A. and Nowick, J. S. (2002) Methylglyoxal synthetase, enol-pyruvaldehyde, glutathione and the glyoxalase system. J. Am. Chem. Soc. 124, 13047-13052
6. Creighton, D. J. and Hamilton, D. S. (2001) Brief history of glyoxalase I and what we have learned about metal ion-dependent, enzyme-catalyzed isomerizations. Arch. Biochem. Biophys. 387, 1-10
7. Kalapos, M. P. (1999) On the promine/retine theory of cell division: now and then. Biochim. Biophys. Acta 1426, 1-16
8. Thornalley, P. J. (1998) Glutathione-dependent detoxification of α-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors. Chem. Biol. Interact. 111-112, 137-151
9. Inoue, Y. and Kimura, A. (1995) Methylglyoxal and regulation of its metabolism in microorganisms. Adv. Microb. Physiol. 37, 177-227
10. Racker, E. (1951) The mechanism of action of glyoxalase. J. Biol. Chem. 190, 685-696
11. Mannervik, B. and Ridderstrom, M. (1993) Catalytic and molecular properties of glyoxalase I. Biochem. Soc. Trans. 21, 515-517
12. Bergdoll, M., Eltis, L. D., Cameron, A. D., Dumas, P. and Bolin, J. T. (1998) All in the family: structural and evolutionary relationships among three modular proteins with diverse functions and variable assembly. Protein Sci. 7, 1661-1670
13. Armstrong, R. N. (2000) Mechanistic diversity in a metalloenzyme superfamily. Biochemistry 39, 13625-13632
14. Pakhomova, S., Rife, C. L., Armstrong, R. N. and Newcomer, M. E. (2004) Structure of fosfomycin resistance protein FosA from transposon Tn2921. Protein Sci. 13, 1260-1265
15. +. J. Am. Chem. Soc 124, 11001-11003
16. Martin, T.W., Dauter, Z., Devedjiev, Y., Sheffield, P., Jelen F., He, M., Sherman, D. H., Otlewski, J., Derewenda, Z. S. and Derewenda, U. (2002) Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein. Structure 10, 933-942
17. Ridderstrom, M. and Mannervik, B. (1996) Optimized heterologous expression of the human zinc enzyme glyoxalase I. Biochem. J. 314, 463-467
18. Aronsson, A. C., Marmstal, E. and Mannervik, B. (1978) Glyoxalase I, a zinc metalloenzyme of mammals and yeast. Biochem. Biophys. Res. Commun. 81, 1235-1240
19. Clugston, S. L., Barnard, J. F., Kinach, R., Miedema, D., Ruman, R., Daub, E. and Honek, J. F. (1998) Overproduction and characterization of a dimeric non-zinc glyoxalase I from Escherichia coli: evidence for optimal activation by nickel ions. Biochemistry 37, 8754-8763
20. Chen, F, Wollmer, M. A., Hoerndli, F., Munch, G., Kuhla, B., Rogaev, E. I., Tsolaki, M., Papassotiropoulos, A. and Gotz, J. (2004) Role for glyoxalase I in Alzheimer's disease. Proc. Natl. Acad. Sci. U.S.A. 101, 7687-7692
21. Vander Jagt, D. L. and Hunsaker, L. A. (2003) Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-1, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase. Chem. Biol. Interact. 143-144, 341-351
22. Beard, K. M., Shangari, N., Wu, B. and O'Brien, P. J. (2003) Metabolism, not autoxidation, plays a role in α-oxoaldehyde- and reducing sugar-induced erythrocyte GSH depletion: relevance for diabetes mellitus. Mol. Cell. Biochem. 252, 331-338
23. Iozef, R., Rahlfs, S., Chang, T., Schirmer, H. and Becker, K. (2003) Glyoxalase I of the malarial parasite Plasmodium falciparum: evidence for subunit fusion. FEBS Lett. 554, 284-288
24. Creighton, D. J., Zheng, Z. B., Holewinski, R., Hamilton, D. S. and Eiseman, J. L. (2003) Glyoxalase I inhibitors in cancer chemotherapy. Biochem. Soc. Trans. 31, 1378-1382
25. Ferguson, G. P., Totemeyer, S., MacLean, M. J. and Booth, I. R. (1998) Methylglyoxal production in bacteria: suicide or survival? Arch. Microbiol. 170, 209-218
26. Thornalley, P. J., Strath, M. and Wilson, R. J. (1994) Antimalarial activity in vitro of the glyoxalase I inhibitor diester, S-p- bromobenzylglutathione diethyl ester. Biochem. Pharmacol. 47, 418-420
27. Barnard, J. F., Vander Jagt, D. L. and Honek, J. F. (1994) Small molecule probes of glyoxalase I and glyoxalase II. Biochim. Biophys. Acta 1208, 127-135
28. Saint-Jean, A. P., Phillips, K. R., Creighton, D. J. and Stone, M. J. (1998) Active monomeric and dimeric forms of Pseudomonas putida glyoxalase I: evidence for 3D domain swapping. Biochemistry 37, 10345-10353
29. Clugston, S. L. and Honek, J. F. (2000) Identification of sequences encoding the detoxification metalloisomerase glyoxalase I in microbial genomes from several pathogenic organisms. J. Mol. Evol. 50, 491-495
30. Bier, M., Ostrem, J. and Marquez, R. B. (1993) A new buffering system and its use in electrophoresis and isoelectric focusing. Electrophoresis 14, 1011-1018
31. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
32. Kizil, G., Wilks, K., Wells, D. and Ala'Aldeen, D. A. A. (2000) Detection and characterisation of the genes encoding glyoxalase I and II from Neisseria meningitidis. J. Med. Microbiol. 49, 669-673
33. Sambrook, J, Fritsch, E. F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Plainsview
34. He, M. M., Clugston, S. L., Honek, J. F. and Matthews, B. W. (2000) Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation. Biochemistry 39, 8719-3727
35. Clugston, S. L., Yajima, R. and Honek, J. F. (2004) Investigation of metal binding and activation of Escherichia coli glyoxalase I: kinetic, thermodynamic and mutagenesis studies. Biochem. J. 377, 309-316
36. Davidson, G., Clugston, S. L., Honek, J. F. and Maroney, M. J. (2000) XAS investigation of the nickel active site structure in Escherichia coli glyoxalase I. Inorg. Chem. 39, 2962-2963
37. Stokvis, E., Clugston, S. L., Honek, J. F. and Heck, A. J. (2000) Characterization of glyoxalase I (E. coli)-inhibitor interactions by electrospray time-of-flight mass spectrometry and enzyme kinetic analysis. J. Protein. Chem. 19, 389-397
38. Davidson, G., Clugston, S. L., Honek, J. F. and Maroney, M. J. (2001) An XAS investigation of product and inhibitor complexes of Ni-containing GlxI from Escherichia coli: mechanistic implications. Biochemistry 40, 4569-4582
39. Cameron, A. D., Olin, B., Ridderstrom, M., Mannervik, B. and Jones, T. A. (1997) Crystal structure of human glyoxalase I - evidence for gene duplication and 3D domain swapping. EMBO J. 16, 3386-3395